Modulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e

scientific article

Modulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2009.264
P932PMC publication ID2839443
P698PubMed publication ID19935781
P5875ResearchGate publication ID40029084

P2093author name stringChristian Mueller
Terence R Flotte
Qiushi Tang
Allison Keeler
Sofia Braag
Timothy Menz
P2860cites workIL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1Q24290462
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivoQ28213431
A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processesQ28247742
Interleukin-13: central mediator of allergic asthmaQ28291712
Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for AtopyQ28296979
The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse modelQ33381294
Activated mast cells produce interleukin 13.Q36364660
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune responseQ36370595
IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligandQ36696547
A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine productionQ37012219
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapyQ37364038
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin productionQ40849898
IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma.Q40981505
Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humansQ42476540
Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosisQ44434322
Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR geneQ45399177
Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice.Q54621653
Purified human peripheral blood basophils release interleukin-13 and preformed interleukin-4 following immunological activationQ61960815
Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTRQ71661844
Interleukin-2 secretion by human B lymphocytes occurs as a late event and requires additional stimulation after CD40 cross-linkingQ71696205
Interleukin-13 and interleukin-4 are coexpressed in atopic asthmaQ71747952
IL-4 induces human B cell maturation and IgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo treatment with an IL-4/IL-13 receptor antagonistQ71829402
IL-10 and IL-13 as B cell growth and differentiation factorsQ72088630
The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activationQ74195817
Increased expression of Interleukin-13 but not Interleukin-4 in cystic fibrosis patientsQ80819694
P433issue3
P304page(s)511-518
P577publication date2009-11-24
P1433published inMolecular TherapyQ15762400
P1476titleModulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e
P478volume18

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cites work (P2860)
Q36251378Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma.
Q42176534Dynamic role of epithelium-derived cytokines in asthma
Q35750626Liposome-based polymer complex as a novel adjuvant: enhancement of specific antibody production and isotype switch

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