Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice

scientific article published on 19 April 2010

Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1017/S003118201000003X
P698PubMed publication ID20398436

P2093author name stringJing Li
Wei Wei
Jun Peng
Qingli Luo
Jilong Shen
Huiqin Wen
Zhengrong Zhong
Xiaoyue Li
P2860cites workInterleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell functionQ24563054
Cellular and molecular mechanisms of fibrosisQ24648892
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responsesQ28115227
A distinct role for interleukin-13 in Th2-cell-mediated immune responsesQ74344715
The cell biology of liver fibrogenesis - an imbalance of proliferation, growth arrest and apoptosis of myofibroblastsQ74531821
Isolation and culture of rat hepatic stellate cellsQ77295691
Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritisQ80041591
Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in ratsQ80489937
Cytokine profile associated with human chronic schistosomiasis mansoniQ80866898
Depolarizing neuromuscular blocking action induced by electropharmacological coupling in the combined effect of paeoniflorin and glycyrrhizinQ93579214
IL-13 effector functionsQ28180348
Effects of total glucosides of peony on immunological hepatic fibrosis in ratsQ33213710
Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA.Q33240148
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory responseQ33853821
Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infectionQ34146893
Cytokine production associated with periportal fibrosis during chronic schistosomiasis mansoni in humansQ34334214
IL-13 receptors and signaling pathways: An evolving webQ35110741
Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expressionQ35632241
Tyrosine kinase inhibitors: a new approach for asthmaQ35692069
Schistosomiasis: implications for world travelers and healthcare providersQ36173878
Immunopathology of schistosomiasisQ36220509
Mechanisms of liver fibrosisQ36247948
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune responseQ36370595
SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesisQ36402678
SOCS proteins, cytokine signalling and immune regulationQ36831668
Expression of SOCS-1 in the liver tissues of chronic hepatitis B and its clinical significanceQ37189619
Cytokine secretion profile associated with periportal fibrosis in S. mansoni-infected Egyptian patientsQ39506882
Antiproliferative activity of aucubin is through cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cellsQ39989490
Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosisQ40187466
Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cellsQ40444779
IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation siteQ40614129
Decoy receptors in the regulation of T helper cell type 2 responsesQ42944812
The collagenolytic effects of the traditional Chinese medicine preparation, Han-Dan-Gan-Le, contribute to reversal of chemical-induced liver fibrosis in ratsQ44292671
P-selectin suppresses hepatic inflammation and fibrosis in mice by regulating interferon gamma and the IL-13 decoy receptorQ44785863
The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in ratsQ44792621
Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblastsQ44991625
Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast-like synoviocytes of collagen induced arthritic ratsQ46372047
Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonolQ46617193
A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophagesQ46685405
The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac modelQ46709192
Effects and mechanisms of crude astragalosides fraction on liver fibrosis in ratsQ46731038
A contributory role for activated hepatic stellate cells in the dynamics of Schistosoma japonicum egg-induced fibrosis.Q50647561
Paeoniflorin inhibits TGF-beta1-mediated collagen production by Schistosoma japonicum soluble egg antigen in vitro.Q50996137
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis.Q52543547
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals.Q52669715
Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis.Q54564697
Hepatic stellate cells in human schistosomiasis mansoni: A comparative immunohistochemical study with liver cirrhosisQ56797183
Th2 Cytokines Are Associated with Persistent Hepatic Fibrosis in HumanSchistosoma japonicumInfectionQ58812311
Implication de l'interleukine 13 et de son récepteur dans la sclérodermie systémiqueQ58852329
Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosisQ64376742
Blocking effects of blended paeoniflorin or its related compounds with glycyrrhizin on neuromuscular junctions in frog and mouseQ70739275
[Pharmacological studies on herb paeony root. II. Anti-inflammatory effect, inhibitory effect on gastric juice secretion, preventive effect on stress ulcer, antidiuretic effect of paeoniflorin and combined effects with licorice component Fm 100]Q71339023
An improved method for the purification of stellate cells from rat liver with dichloromethylene diphosphate (CL2MDP)Q73584331
P433issue8
P921main subjectschistosomiasisQ221159
P304page(s)1213-1225
P577publication date2010-04-19
P1433published inParasitologyQ15753259
P1476titlePaeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice
P478volume137

Reverse relations

cites work (P2860)
Q38859767A Pharmacological Review of Bioactive Constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch
Q35741426An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum.
Q26741501Assessment of the Therapeutic Effect of Total Glucosides of Peony for Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analysis
Q92236563Efficacy and safety of total glucosides of paeony combined with methotrexate and leflunomide for active rheumatoid arthritis: a meta-analysis
Q48245143Identification of bioactive compounds in Shaoyao-Gancao decoction using β2-adrenoceptor affinity chromatography.
Q39619367Inflammatory cytokines IFN-γ, IL-4, IL-13 and TNF-α alterations in schistosomiasis: a meta-analysis
Q45424887Paeoniflorin acts as a liver X receptor agonist
Q54570243Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages.
Q35885340Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration
Q36955213Paeoniflorin protects diabetic mice against myocardial ischemic injury via the transient receptor potential vanilloid 1/calcitonin gene-related peptide pathway
Q35494410Potent natural products and herbal medicines for treating liver fibrosis
Q36022175The Inhibition of Mast Cell Activation of Radix Paeoniae alba Extraction Identified by TCRP Based and Conventional Cell Function Assay Systems
Q64235907The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6'-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases

Search more.