Management of fibrosis: the mesenchymal stromal cells breakthrough

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Management of fibrosis: the mesenchymal stromal cells breakthrough is …
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scholarly articleQ13442814

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P356DOI10.1155/2014/340257
P3181OpenCitations bibliographic resource ID1262160
P932PMC publication ID4123563
P698PubMed publication ID25132856
P5875ResearchGate publication ID265337128

P50authorAlain ChapelQ57090355
P2093author name stringMarc Benderitter
Radia Tamarat
Benoît Usunier
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Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanismsQ47248012
Global gene expression profiles reveal an increase in mRNA levels of collagens, MMPs, and TIMPs in late radiation enteritisQ47392212
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Cardiac fibrosis and cellular hypertrophy decrease the degree of reverse remodeling and improvement in cardiac function during left ventricular assist.Q53339381
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Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.Q54473910
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Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patientsQ83414034
A novel therapeutic regimen for hepatic fibrosis using the combination of mesenchymal stem cells and baicalinQ83579117
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed ratsQ83963300
Melatonin treatment improves adipose-derived mesenchymal stem cell therapy for acute lung ischemia-reperfusion injuryQ85315225
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Endothelial-to-mesenchymal transition contributes to cardiac fibrosisQ29620566
Human mesenchymal stem cells modulate B-cell functionsQ29620705
Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.Q31095344
Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidneyQ33333234
Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosisQ33683193
Transplanted human amniotic membrane-derived mesenchymal stem cells ameliorate carbon tetrachloride-induced liver cirrhosis in mouseQ33822241
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.Q33924416
Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidneyQ33995109
Renoprotective properties of pirfenidone in subtotally nephrectomized ratsQ34087790
Nucleic Acid recognition by metal complexes of bleomycinQ34105633
Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiationQ34116215
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trialsQ34469147
Arterially transplanted mesenchymal stem cells in a mouse reversible unilateral ureteral obstruction model: in vivo bioluminescence imaging and effects on renal fibrosisQ34722231
Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide synthase.Q34761461
HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are AntifibroticQ34804461
Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reactionQ35038567
Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological ModelQ35112180
Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis.Q35124912
Autologous transplantation of adipose-derived mesenchymal stem cells markedly reduced acute ischemia-reperfusion lung injury in a rodent modelQ35161538
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effectsQ35168236
Cardiac remodelling in end stage heart failure: upregulation of matrix metalloproteinase (MMP) irrespective of the underlying disease, and evidence for a direct inhibitory effect of ACE inhibitors on MMP.Q35580538
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseasesQ35649473
Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.Q35840642
The biology of the myofibroblastQ36058077
Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosisQ36165804
Adipose derived mesenchymal stem cells transplantation via portal vein improves microcirculation and ameliorates liver fibrosis induced by CCl4 in ratsQ36226666
Relevance of matrix metalloproteinases and their inhibitors after myocardial infarction: a temporal and spatial windowQ36344710
A review of current and novel therapies for idiopathic pulmonary fibrosisQ36542274
Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trialQ36603453
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionQ36634299
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosisQ36648004
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-betaQ36663630
Mesenchymal stem cell delivery into rat infarcted myocardium using a porous polysaccharide-based scaffold: a quantitative comparison with endocardial injectionQ36765397
Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in miceQ36794471
Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I studyQ36861751
Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosisQ36981313
Murine models of pulmonary fibrosis.Q36997546
Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-β1 signalingQ37064631
How do mesenchymal stromal cells suppress T cells?Q37121074
Repeated autologous bone marrow-derived mesenchymal stem cell injections improve radiation-induced proctitis in pigsQ37255064
Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury.Q37257183
New insights for pelvic radiation disease treatment: Multipotent stromal cell is a promise mainstay treatment for the restoration of abdominopelvic severe chronic damages induced by radiotherapyQ37266540
Growth factors and cytokines in wound healingQ37364066
Intestinal fibrosis in IBD--a dynamic, multifactorial processQ37433780
Therapeutic use of stem cell transplantation for cell replacement or cytoprotective effect of microvesicle released from mesenchymal stem cellQ37604825
Evaluating pancreatitis in primary care: a population-based cohort studyQ37725828
Translation of stem cell therapy for neurological diseasesQ37783805
Mesenchymal stem cells: mechanisms of inflammationQ37809081
Strategies for anti-fibrotic therapiesQ38069742
Hepatocyte growth factor is an attractive target for the treatment of pulmonary fibrosisQ38088776
Gastro-intestinal autoimmunity: preclinical experiences and successful therapy of fistulizing bowel diseases and gut Graft versus host disease by mesenchymal stromal cells.Q38096939
Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.Q38302488
Reduction of fibrosis in dibutyltin dichloride-induced chronic pancreatitis using rat umbilical mesenchymal stem cells from Wharton's jellyQ39327403
Suppression of carbon tetrachloride-induced liver fibrosis by transplantation of a clonal mesenchymal stem cell line derived from rat bone marrowQ39846145
The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosisQ39984252
Therapeutic effects of bone marrow-derived mesenchymal stem cells engraftment on bleomycin-induced lung injury in ratsQ40075896
Interactions between human mesenchymal stem cells and natural killer cellsQ40385365
Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymesQ40734989
Mesenchymal stem cell therapy prevents interstitial fibrosis and tubular atrophy in a rat kidney allograft modelQ41255321
Arterially Delivered Mesenchymal Stem Cells Prevent Obstruction-Induced Renal FibrosisQ41418374
Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosisQ41690993
Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantationQ42095796
Effect of mesenchymal stem cells on Doxorubicin-induced fibrosisQ42217160
CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cellsQ42437301
Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesisQ42513510
Human mesenchymal stem cells provide protection against radiation-induced liver injury by antioxidative process, vasculature protection, hepatocyte differentiation, and trophic effects.Q42793902
Mesenchymal stem cell infusion therapy in a carbon tetrachloride-induced liver fibrosis model affects matrix metalloproteinase expression.Q43152962
Mesenchymal Stem Cells Home to Sites of Injury and InflammationQ43198512
Allogeneic transplantation of fetal membrane-derived mesenchymal stem cell sheets increases neovascularization and improves cardiac function after myocardial infarction in ratsQ44288499
Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in miceQ44981280
The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2.Q45167503
Reduction of postischemic immune inflammatory response: an effective strategy for attenuating chronic allograft nephropathyQ45235006
Mesenchymal stem cells facilitate recovery from chemically induced liver damage and decrease liver fibrosisQ45400930
Evaluation of polyelectrolyte complex-based scaffolds for mesenchymal stem cell therapy in cardiac ischemia treatment.Q45890702
Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial.Q46004819
Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injuryQ46073081
Mesenchymal stem cell transplantation attenuates cardiac fibrosis associated with isoproterenol-induced global heart failureQ46376455
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)340257
P577publication date2014-07-14
P1433published inStem Cells InternationalQ26842114
P1476titleManagement of fibrosis: the mesenchymal stromal cells breakthrough
P478volume2014

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