T-cell positioning by chemokines in autoimmune skin diseases

scientific article published on 01 May 2019

T-cell positioning by chemokines in autoimmune skin diseases is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/IMR.12762
P932PMC publication ID6553463
P698PubMed publication ID30977191

P50authorJohn E HarrisQ90321378
James P StrassnerQ88596432
P2093author name stringKingsley I Essien
Jillian M Richmond
P2860cites workAn integrated model of alopecia areata biomarkers highlights both TH1 and TH2 upregulationQ89454382
Peripheral Tissue Chemokines: Homeostatic Control of Immune Surveillance T CellsQ90004463
A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivityQ90965765
Mouse Model for Human VitiligoQ91727091
Resident Memory and Recirculating Memory T Cells Cooperate to Maintain Disease in a Mouse Model of VitiligoQ93037335
CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cellsQ22010907
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 responseQ24613860
Identification of human CCR8 as a CCL18 receptorQ24618546
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodelingQ24647357
Cellular and molecular mechanisms of fibrosisQ24648892
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egressQ24650866
Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cellsQ24676386
CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.Q36677670
TSLP in epithelial cell and dendritic cell cross talkQ36819179
From the brain-skin connection: the neuroendocrine-immune misalliance of stress and itchQ36914941
TSLP acts on infiltrating effector T cells to drive allergic skin inflammationQ36954478
Cutting Edge: Chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4 T cells under physiological conditions.Q36955664
CCR6 as a possible therapeutic target in psoriasisQ36980670
Molecular signatures define alopecia areata subtypes and transcriptional biomarkersQ37008476
CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host diseaseQ37065718
Hormonal regulation of B-cell function and systemic lupus erythematosusQ37186307
Reduced skin homing by functional Treg in vitiligoQ37187413
CCR6 is required for IL-23-induced psoriasis-like inflammation in miceQ37286597
CCL22 to Activate Treg Migration and Suppress Depigmentation in VitiligoQ37299737
Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID miceQ37376897
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.Q37468713
Memory regulatory T cells reside in human skinQ37602195
Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in miceQ37700821
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitisQ37709681
Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlatesQ37778645
CXCR3 ligands: redundant, collaborative and antagonistic functionsQ37827339
Harnessing dendritic cells in inflammatory skin diseases.Q37835969
Cockroach induces inflammatory responses through protease-dependent pathwaysQ37885639
The human cutaneous chemokine system.Q38008335
Regulation of cellular processes by interleukin-16 in homeostasis and cancerQ38124813
Chemokine receptors in psoriasisQ38144211
Photosensitivity, apoptosis, and cytokines in the pathogenesis of lupus erythematosus: a critical review.Q38178160
Chemokines and chemokine receptors: positioning cells for host defense and immunityQ38198156
Mechanisms regulating skin immunity and inflammationQ38203783
The origins and functions of dendritic cells and macrophages in the skinQ38214043
The immunopathology of cutaneous lupus erythematosusQ38230698
CCR4 and its ligands: from bench to bedsideQ38236403
Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasisQ38412949
CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiationQ38456783
TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasisQ38647664
Circulating CXCL10 is increased in non-segmental vitiligo, in presence or absence of autoimmune thyroiditis.Q38683576
Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptorQ24683742
Mogamulizumab for the treatment of cutaneous T-cell lymphoma: recent advances and clinical potentialQ26744275
CXCL14 as an emerging immune and inflammatory modulatorQ26770790
Macrophage and Innate Lymphoid Cell Interplay in the Genesis of FibrosisQ26774652
The Beginning of the End: CXCR3 Signaling in Late-Stage Wound HealingQ26830246
Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulationQ27317270
Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc ComplexQ27679932
Pseudoexons and regulatory elements in the genomic sequence of the beta-chemokine, alternative macrophage activation-associated CC-chemokine (AMAC)-1Q28144510
Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophilsQ28205971
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)Q28211911
CCL27-CCR10 interactions regulate T cell-mediated skin inflammationQ28217086
DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27Q28285583
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cellsQ28302789
CCR6 regulates the migration of inflammatory and regulatory T cellsQ28511778
Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1Q28591681
T-Cell Function and Migration — Two Sides of the Same CoinQ29041098
CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptorsQ30432672
Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic miceQ30433217
Visualizing CD4 T-cell migration into inflamed skin and its inhibition by CCR4/CCR10 blockades using in vivo imaging modelQ30498155
Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.Q30528857
Sensing and alarm function of resident memory CD8⁺ T cellsQ30539038
Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathwaysQ30543898
Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccineQ30585157
CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human SkinQ33390838
Lack of CXC chemokine receptor 3 signaling leads to hypertrophic and hypercellular scarringQ33745172
Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasisQ33760897
Alopecia areata, stress and psychiatric disorders: a reviewQ33770351
CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligoQ33864128
Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesisQ33941199
Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.Q33970584
A mechanism for the initiation of allergen-induced T helper type 2 responsesQ34010133
Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.Q34024439
The role of TNF inhibitors in psoriasis therapy: new implications for associated comorbiditiesQ34076431
Sensing the outside world: TSLP regulates barrier immunity.Q34076759
Two Phase 3 Trials of Dupilumab versus Placebo in Atopic DermatitisQ47651802
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones.Q47748712
Thymus- and activation-regulated chemokine (TARC/CCL17) induces a Th2-dominated inflammatory reaction on intradermal injection in miceQ47759791
Repigmentation in vitiligo using the Janus kinase inhibitor tofacitinib may require concomitant light exposure.Q47929993
IL-15 Complexes Induce Migration of Resting Memory CD8 T Cells into Mucosal TissuesQ47944236
Systemic symptoms in the progression of cutaneous to systemic lupus erythematosusQ48361989
Secukinumab: a review of the anti-IL-17A biologic for the treatment of psoriasis.Q49985388
Vitiligo Skin Is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3.Q50014282
CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin.Q50088147
Minimally invasive skin tape strip RNA sequencing identifies novel characteristics of the type 2-high atopic dermatitis disease endotype.Q50138116
RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo.Q50149925
Epigallocatechin-3-gallate (EGCG) Suppresses the Trafficking of Lymphocytes to Epidermal Melanocytes via Inhibition of JAK2: Its Implication for Vitiligo Treatment.Q50246489
Preferential migration of T regulatory cells induced by IL-16.Q50658836
Differing requirements for CCR4, E-selectin, and α4β1 for the migration of memory CD4 and activated T cells to dermal inflammation.Q50952121
Transcriptional and Cytokine Profiles Identify CXCL9 as a Biomarker of Disease Activity in Morphea.Q51031439
Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib.Q51066393
Decreased regulatory T-cells and CD4(+) /CD8(+) ratio correlate with disease onset and progression in patients with generalized vitiligo.Q51075988
CXCR3 Depleting Antibodies Prevent and Reverse Vitiligo in Mice.Q51167268
Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease.Q51448115
Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial.Q51637913
Structure and Distribution of an Unrecognized Interstitium in Human Tissues.Q51731097
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.Q51983318
The vast majority of CLA+ T cells are resident in normal skin.Q51984006
CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells.Q51995031
FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to nonlymphoid tissue homing receptors in secondary lymphoid tissues.Q51998740
Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.Q52587547
Percutaneous application of peptidoglycan from Staphylococcus aureus induces infiltration of CCR4+ cells into mouse skin.Q52616118
CCR4 Is Critically Involved in Skin Allergic Inflammation of BALB/c Mice.Q52728536
Correlation between serum IL-16 and atopic dermatitis.Q53128421
Use of a Canine Model of Atopic Dermatitis to Investigate the Efficacy of a CCR4 Antagonist in Allergen-Induced Skin Inflammation in a Randomized Study.Q53174921
Biomarkers of alopecia areata disease activity and response to corticosteroid treatment.Q53246365
Association between serum IL-16 levels and the degree of sensitization in patients with atopic dermatitis.Q53257944
Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures.Q53318728
Distinctive Treg associated CCR4-CCL22 expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris.Q53461072
Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib.Q53662237
Interferon-gamma-deficient mice are resistant to the development of alopecia areata.Q53766814
Topical Ruxolitinib for the Treatment of Alopecia Universalis.Q54229292
Crosstalk between TGF-β1 and CXCR3 signaling during urethral fibrosis.Q54346484
CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes.Q54434490
Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.Q54439509
Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis.Q54459614
Association between IL16 gene polymorphisms and susceptibility to alopecia areata in the Korean population.Q54469372
JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.Q54513818
Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.Q54664588
Treatment of generalized deep morphea and eosinophilic fasciitis with the Janus kinase inhibitor tofacitinib.Q55519143
Alopecia AreataQ56286428
CCR5-dependent regulatory T cell migration mediates fungal survival and severe immunosuppressionQ56900772
Systemic and local characterization of regulatory T cells in a chronic fungal infection in humansQ56901852
CC Chemokine Ligand 18, An Atopic Dermatitis-Associated and Dendritic Cell-Derived Chemokine, Is Regulated by Staphylococcal Products and Allergen ExposureQ56966131
Substance P as an Immunomodulatory Neuropeptide in a Mouse Model for Autoimmune Hair Loss (Alopecia Areata)Q56990592
Type I interferon signature in the initiation of the immune response in vitiligoQ56996562
Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and ProgressionQ38718909
Cutaneous Lupus Erythematosus: An Update on Pathogenesis, Diagnosis and TreatmentQ38731631
Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes.Q38732156
Clinical phenotypes and endophenotypes of atopic dermatitis: Where are we, and where should we go?Q38733185
Understanding autoimmunity of vitiligo and alopecia areataQ38837287
Cutaneous lupus erythematosus: updates on pathogenesis and associations with systemic lupusQ38857518
Drug-induced cutaneous lupus erythematosus: 88 new cases.Q38995512
Skin-derived TSLP systemically expands regulatory T cellsQ38996948
JAK inhibitors in dermatology: The promise of a new drug classQ39111032
Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients.Q39212867
Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnesQ39253844
Overexpression of CXCL16 in lesional psoriatic skinQ39533961
CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia AreataQ39604573
A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligationQ39737420
Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic ItchQ40058426
Increased expression of CXCR3 and its ligands in patients with vitiligo and CXCL10 as a potential clinical marker for vitiligoQ40072169
Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skinQ40158221
Elevated homocysteine levels in suction-induced blister fluid of active vitiligo lesionsQ40200413
Baricitinib versus Placebo or Adalimumab in Rheumatoid ArthritisQ40332185
The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and HomeostasisQ40414812
Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice.Q40425124
Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?Q40506697
Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2.Q40533463
Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 functionQ40554316
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewingQ40598102
CCR4 in human allergen-induced late responses in the skin and lungQ40718567
Baricitinib in Patients with Refractory Rheumatoid ArthritisQ40735626
Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4Q40794919
A randomized phase 2b trial of baricitinib, an oral Janus kinase (JAK) 1/JAK2 inhibitor, in patients with moderate-to-severe psoriasis.Q40821601
Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissuesQ40911505
Renbok phenomenon and contact sensitization in a patient with alopecia universalisQ41171805
The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasisQ41620801
T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert.Q41717756
Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of sclerodermaQ41789272
Mogamulizumab for relapsed adult T-cell leukemia-lymphoma: Updated follow-up analysis of phase I and II studiesQ41932624
Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissueQ42048427
A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skinQ42145851
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.Q42259563
In three types of interface dermatitis, different patterns of expression of intercellular adhesion molecule-1 (ICAM-1) indicate different triggers of diseaseQ42480631
Cytokine mRNA levels in Alopecia areata before and after treatment with the contact allergen diphenylcyclopropenoneQ42492052
Autocrine regulation of re-epithelialization after wounding by chemokine receptors CCR1, CCR10, CXCR1, CXCR2, and CXCR3.Q42493138
Differential expression of CXCR3 targeting chemokines CXCL10, CXCL9, and CXCL11 in different types of skin inflammationQ42509243
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cellsQ42767760
SFRP2/DPP4 and FMO1/LSP1 define major fibroblast populations in human skinQ42778321
Chemotactic signaling and beyond: link between interleukin-16 and axonal degeneration in multiple sclerosisQ43099559
Interaction between CX3CL1 and CX3CR1 regulates vasculitis induced by immune complex depositionQ43630149
Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupusQ43699034
CXCR3 deficiency prolongs Th1-type contact hypersensitivityQ43806136
House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.Q44172242
Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.Q44479151
Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinibQ44868185
Delayed reepithelialization and basement membrane regeneration after wounding in mice lacking CXCR3.Q34083641
Anti-angiogenic effects of epigallocatechin-3-gallate in human skinQ34104237
CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.Q34156849
Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergenQ34161524
Homing and cellular traffic in lymph nodesQ34282818
Global activation of CD8+ cytotoxic T lymphocytes correlates with an impairment in regulatory T cells in patients with generalized vitiligoQ34287499
The role of substance P in inflammatory diseaseQ34343982
An early reduction in Treg cells correlates with enhanced local inflammation in cutaneous leishmaniasis in CCR6-deficient miceQ34427121
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.Q34433867
Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cellsQ34444540
Tofacitinib Citrate for the Treatment of Vitiligo: A Pathogenesis-Directed TherapyQ34482156
Local immune response in skin of generalized vitiligo patients. Destruction of melanocytes is associated with the prominent presence of CLA+ T cells at the perilesional siteQ34510273
Chemokines and the tissue-specific migration of lymphocytesQ34515703
Proton pump inhibitor-induced subacute cutaneous lupus erythematosusQ34516486
Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers.Q34523843
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areataQ34541893
Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata.Q34541899
Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesisQ34616359
T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cellsQ34626234
The IL-21 receptor augments Th2 effector function and alternative macrophage activationQ34682153
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokinesQ34762409
Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.Q34966662
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.Q35006074
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalitiesQ35084580
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.Q35132544
Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responsesQ35184456
Alopecia areata: treatment of today and tomorrowQ35190527
Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.Q35586076
Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosisQ35620315
Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance.Q35773559
Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor BaricitinibQ35800753
Small Molecule CXCR3 AntagonistsQ35831696
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host diseaseQ35848458
CXCR3 Signaling Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Controlling the Parenchymal Distribution of Effector and Regulatory T Cells in the Central Nervous SystemQ57209761
Association of allergic contact dermatitis with a promoter polymorphism in the IL16 geneQ57338189
Punch Grafting versus Suction Blister Epidermal Grafting in the Treatment of Stable Lip VitiligoQ58623428
Cutting Edge: Expression of Chemokine Receptor CXCR1 on Human Effector CD8+ T CellsQ58755839
Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligoQ59356549
Simultaneous improvement of alopecia universalis and atopic dermatitis in a patient treated with a JAK inhibitorQ60843768
Melanocytes in psoriasis: convicted culprit or bullied bystander?Q64973006
Modulation of growth and differentiation in normal human keratinocytes by transforming growth factor-betaQ68556740
Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical studyQ71038378
Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitisQ71829930
Alopecia areata in aging C3H/HeJ miceQ72001887
Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patientsQ72037404
Lesional expression of interferon-gamma in atopic eczemaQ72665549
The effect of hormonal changes on cutaneous disease in lupus erythematosusQ72919038
Role of cytotoxic T cells in chronic alopecia areataQ73322016
"Lymphoid" chemokine messenger RNA expression by epithelial cells in the chronic inflammatory lesion of the salivary glands of Sjögren's syndrome patients: possible participation in lymphoid structure formationQ73565836
Increased basic fibroblast growth factor levels in serum and blister fluid from patients with vitiligoQ73598017
The human hair follicle immune system: cellular composition and immune privilegeQ73789525
Airway remodeling is absent in CCR1-/- mice during chronic fungal allergic airway diseaseQ74027234
Modified technique of suction blistering for epidermal grafting in vitiligoQ77734510
Gene expression in bronchoalveolar lavage cells from scleroderma patientsQ77995648
Levels of soluble interleukin-2 receptor in the sera and skin tissue fluids of patients with vitiligoQ78195032
Chemokine responses distinguish chemical-induced allergic from irritant skin inflammation: memory T cells make the differenceQ79872393
CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuliQ79951348
Fucosyltransferase VII-positive, skin-homing T cells in the blood and skin lesions of atopic dermatitis patientsQ80172728
Maintenance of hair follicle immune privilege is linked to prevention of NK cell attackQ80413604
The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsetsQ80832474
Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis modelQ81009296
Interleukin-16 in patients with alopecia areataQ81198812
Alopecia areata induced in C3H/HeJ mice by interferon-gamma: evidence for loss of immune privilegeQ81283837
Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosusQ81349191
CXCL16 and CXCR6 are upregulated in psoriasis and mediate cutaneous recruitment of human CD8+ T cellsQ82661651
CCL18 is expressed in patients with bullous pemphigoid and parallels disease courseQ83140582
Investigation of the inflammatory mechanisms in alopecia areataQ83207634
Type 1 interferon signature in the scalp lesions of alopecia areataQ83932317
Serum CXCL16 concentrations correlate with the extent of skin sclerosis in patients with systemic sclerosisQ84236518
CXCL10 produced from hair follicles induces Th1 and Tc1 cell infiltration in the acute phase of alopecia areata followed by sustained Tc1 accumulation in the chronic phaseQ85891593
Atopic dermatitisQ86174273
Serum thymus and activation-regulated chemokine as disease activity and response biomarker in alopecia areataQ86489325
Promoter demethylation contributes to TSLP overexpression in skin lesions of patients with atopic dermatitisQ86954617
Understanding how cutaneous lupus erythematosus progresses to systemic lupus erythematosusQ87194335
Dupilumab treatment in adults with moderate-to-severe atopic dermatitisQ87371931
Stratum corneum profiles of inflammatory mediators in patch test reactions to common contact allergens and sodium lauryl sulfateQ87768981
Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itchQ88562137
JAK-STAT signaling pathway inhibition: a role for treatment of discoid lupus erythematosus and dermatomyositisQ89004946
Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammationQ89060748
Regulatory T cells in autoimmune diseaseQ89171054
TSLP produced by keratinocytes promotes allergen sensitization through skin and thereby triggers atopic march in miceQ44998295
Human T cells that are able to produce IL-17 express the chemokine receptor CCR6.Q45054355
Dermal clusters of mature dendritic cells and T cells are associated with the CCL20/CCR6 chemokine system in chronic psoriasisQ45847335
Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascadeQ45897140
Induction of eosinophil- and Th2-attracting epidermal chemokines and cutaneous late-phase reaction in tape-stripped skin.Q45950978
Suction blistering the lesional skin of vitiligo patients reveals useful biomarkers of disease activityQ46312769
The role of interleukin-16 in murine contact hypersensitivityQ46419639
Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickelQ46685847
CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli.Q46760246
CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivityQ46839201
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leakQ46861210
Expression of chemokine receptor CCR4 and its ligands (CCL17 and CCL22) in murine contact hypersensitivityQ46871487
Sensory TRP channels contribute differentially to skin inflammation and persistent itch.Q47132169
Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10.Q47324915
Role of chemokines and the corresponding receptors in vitiligo: A pilot studyQ47426230
Cytokine modulation of atopic itchQ89211309
Melanocyte antigen triggers autoimmunity in human psoriasisQ35856465
Lymphocytes, neuropeptides, and genes involved in alopecia areataQ35916135
Increased expression of Cxcr3 and its ligands, Cxcl9 and Cxcl10, during the development of alopecia areata in the mouse.Q35962329
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophagesQ36021832
JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin DiseasesQ36155239
Nociceptive Sensory Fibers Drive Interleukin-23 Production from CD301b+ Dermal Dendritic Cells and Drive Protective Cutaneous ImmunityQ36165375
Assessment of Interleukin 16 Serum Levels and Skin Expression in Psoriasis Patients in Correlation with Clinical Severity of the Disease.Q36176403
Targeting chemokine receptor CCR4 in adult T-cell leukemia-lymphoma and other T-cell lymphomasQ36183430
Probing the effects of stress mediators on the human hair follicle: substance P holds central positionQ36202856
Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory diseaseQ36229433
Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes.Q36241951
IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T CellsQ36304913
Neuroimmunoendocrine circuitry of the 'brain-skin connection'.Q36306022
Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profilesQ36307704
Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal SkinQ36323325
CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skinQ36370073
How are T(H)2-type immune responses initiated and amplified?Q36394985
A skin-selective homing mechanism for human immune surveillance T cellsQ36399490
Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skinQ36402793
A vaccine strategy that protects against genital herpes by establishing local memory T cellsQ36403540
Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA).Q36479531
The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine designQ36547207
Not-so-sweet sixteen: the role of IL-16 in infectious and immune-mediated inflammatory diseasesQ36553595
P433issue1
P921main subjectskin diseaseQ949302
P304page(s)186-204
P577publication date2019-05-01
P1433published inImmunological ReviewsQ15724582
P1476titleT-cell positioning by chemokines in autoimmune skin diseases
P478volume289

Reverse relations

Q97588865Development and characterization of novel mouse monoclonal antibodies against chicken chemokine CC motif ligand 4cites workP2860

Search more.