IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo

scientific article published on 31 October 2006

IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2006-05-021600
P698PubMed publication ID17077330
P5875ResearchGate publication ID6719889

P50authorManfred KopfQ45733155
Nicola L HarrisQ54269369
P2093author name stringBenjamin J Marsland
Anja Fröhlich
Martin R Hodge
Ivo Sonderegger
Michael Kurrer
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)2023-2031
P577publication date2006-10-31
P1433published inBloodQ885070
P1476titleIL-21 receptor signaling is integral to the development of Th2 effector responses in vivo
P478volume109

Reverse relations

cites work (P2860)
Q34727436A nonredundant role for IL-21 receptor signaling in plasma cell differentiation and protective type 2 immunity against gastrointestinal helminth infection
Q34243351A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
Q30276530Advances of the interleukin-21 signaling pathway in immunity and angiogenesis
Q34643444Altered effector CD4+ T cell function in IL-21R-/- CD4+ T cell-mediated graft-versus-host disease
Q37721788Alternatively Activated Macrophages Revisited: New Insights into the Regulation of Immunity, Inflammation and Metabolic Function following Parasite Infection
Q36911886Alternatively activated macrophages in helminth infections
Q34135558Averting inflammation by targeting the cytokine environment
Q24648892Cellular and molecular mechanisms of fibrosis
Q33743673Characterisation of effector mechanisms at the host:parasite interface during the immune response to tissue-dwelling intestinal nematode parasites
Q33993393Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.
Q34305867Combined multivariate and pathway analyses show that allergen-induced gene expression changes in CD4+ T cells are reversed by glucocorticoids
Q39743937Cultivation of Heligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products
Q36970182Cytokine receptors and hematopoietic differentiation
Q37977126Direct and indirect regulatory mechanisms in TH17 cell differentiation and functions
Q35207997Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria
Q40468936Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation.
Q33387434Elevated interleukin-21 correlated to Th17 and Th1 cells in patients with immune thrombocytopenia
Q36389926Endosomal Toll-like receptors in clinically overt and silent autoimmunity
Q91720874Eosinophils and Macrophages within the Th2-Induced Granuloma: Balancing Killing and Healing in a Tight Space
Q34547617Exclusion of IL-21 in the pathogenesis of OVA-induced asthma in mice.
Q46022940Expansion of regulatory T cells from umbilical cord blood and adult peripheral blood CD4(+)CD25 (+) T cells.
Q64230023Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines
Q42372038Grail controls Th2 cell development by targeting STAT6 for degradation
Q47774368IL-17 and related cytokines involved in systemic sclerosis: Perspectives
Q41691958IL-21 Modulates Activation of NKT Cells in Patients with Stage IV Malignant Melanoma
Q36304913IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells
Q46546464IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo
Q38889721IL-21 and T Cell Differentiation: Consider the Context
Q41206789IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma
Q36112397IL-21 is critical for GVHD in a mouse model
Q24644925IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
Q52641602IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner.
Q41973852IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells
Q64953106IL-21 receptor signaling is essential for control of hepatocellular carcinoma growth and immunological memory for tumor challenge.
Q33851806IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses
Q83692712IL-21 reduces immediate hypersensitivity reactions in mouse skin by suppressing mast cell activation or IgE production
Q34733589IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.
Q37397323IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection.
Q37193419IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice
Q64107780IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to
Q37036021IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.
Q24309586Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease
Q37923560Immune modulation and modulators in Heligmosomoides polygyrus infection.
Q28276729Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus
Q28307203Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection
Q92190807Interleukin (IL)-21 in Inflammation and Immunity During Parasitic Diseases
Q36803809Interleukin 21: a cytokine/cytokine receptor system that has come of age
Q38206058Interleukin-21: a double-edged sword with therapeutic potential
Q34388287Interleukin-21: a multifunctional regulator of immunity to infections
Q34002864Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus
Q37129666Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities
Q34408137Kinetics of T helper subsets and associated cytokines correlate well with the clinical activity of graft-versus-host disease
Q36307488Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice
Q37296295Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
Q57232562Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages
Q37621244New insights into the differentiation and function of T follicular helper cells.
Q28388425Pulmonary fibrosis: pathogenesis, etiology and regulation
Q37371070Regulation of helminth-induced Th2 responses by thymic stromal lymphopoietin
Q36232198Regulation of inflammation by interleukin-4: a review of "alternatives"
Q49332756Role of genetics in peripheral arterial disease outcomes; significance of limb-salvage quantitative locus-1 genes.
Q92538835T Follicular Helper Cell Subsets and the Associated Cytokine IL-21 in the Pathogenesis and Therapy of Asthma
Q24645365T follicular helper cells differentiate from Th2 cells in response to helminth antigens
Q81681394T helper cell differentiation: IL-21 and T helper cell differentiation: Jack of all trades?
Q38042721Targeting interleukins to treat severe asthma
Q40561266The Transcription Factor AP4 Mediates Resolution of Chronic Viral Infection through Amplification of Germinal Center B Cell Responses.
Q36897846The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer
Q86415886The capacity of Th2 lymphocytes to deliver B-cell help requires expression of the transcription factor STAT3
Q38197621The emerging role of interleukin-21 in allergic diseases (Review).
Q36879974The multifaceted role of CD4(+) T cells in CD8(+) T cell memory
Q39459081The regulation of gut mucosal IgA B-cell responses: recent developments
Q90079316To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections
Q36265092Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype
Q34303377Transcriptome patterns from primary cutaneous Leishmania braziliensis infections associate with eventual development of mucosal disease in humans
Q37633356Whole blood assay and visceral leishmaniasis: Challenges and promises

Search more.