| scholarly article | Q13442814 |
| P50 | author | Jose M Teixeira | Q41678012 |
| Tomoko Kaneko-Tarui | Q59705835 | ||
| Yoshihiro Tanaka | Q71054126 | ||
| P2093 | author name string | Lihua Zhang | |
| Christopher P Crum | |||
| Pradeep S Tanwar | |||
| P2860 | cites work | LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis | Q24319729 |
| S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway | Q24603083 | ||
| Cellular and molecular mechanisms of fibrosis | Q24648892 | ||
| Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN | Q27335766 | ||
| A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells | Q28204697 | ||
| The AMP-activated protein kinase cascade--a unifying system for energy control | Q28239257 | ||
| The tumor suppressor kinase LKB1: lessons from mouse models | Q37934215 | ||
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| Remodeling of the human endometrial epithelium is regulated by laminin and type IV collagen | Q39894297 | ||
| Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma | Q39986345 | ||
| Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy | Q40040127 | ||
| Disseminated cervical adenoma malignum and bilateral ovarian sex cord tumors with annular tubules associated with Peutz-Jeghers syndrome | Q40755065 | ||
| Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome | Q41022988 | ||
| Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms | Q41982039 | ||
| Adenoma malignum (minimal deviation adenocarcinoma) of the uterine cervix. A clinicopathological and immunohistochemical analysis of 26 cases | Q42499229 | ||
| Activation of mTOR signaling pathway contributes to survival of cervical cancer cells | Q43183757 | ||
| Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. | Q43289515 | ||
| Epithelial-stromal tissue interaction in paramesonephric (Müllerian) epithelial differentiation. | Q43849639 | ||
| Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway. | Q45923710 | ||
| Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. | Q46011005 | ||
| De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine | Q47961996 | ||
| Generation of a conditional disruption of the Tsc2 gene | Q48299820 | ||
| Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas. | Q51716801 | ||
| Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the Mullerian ducts and urogenital sinus during development of the uterus and vagina in mice | Q52309252 | ||
| Epithelioid leiomyosarcoma originating in a hamartomatous polyp from a patient with Peutz-Jeghers syndrome. | Q53544646 | ||
| A case of Peutz-Jeghers syndrome with breast cancer, bilateral sex cord tumor with annular tubules, and adenoma malignum caused by STK11 gene mutation. | Q54706260 | ||
| TGF-?-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system | Q60609528 | ||
| Basement membrane components in normal hyperplastic and neoplastic endometrium | Q68408718 | ||
| Mouse endometrial stromal cells produce basement-membrane components | Q68916672 | ||
| Mucinous lesions of the fallopian tube. A report of seven cases | Q72850960 | ||
| Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium | Q81417028 | ||
| Uterotubal transport disorder in adenomyosis and endometriosis--a cause for infertility | Q83924433 | ||
| The LKB1 tumor suppressor negatively regulates mTOR signaling | Q28272728 | ||
| A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome | Q28307804 | ||
| Requirement of Bmpr1a for Müllerian duct regression during male sexual development | Q28504908 | ||
| Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis | Q28505230 | ||
| Pax-2 controls multiple steps of urogenital development | Q28586799 | ||
| Stromal fibroblasts in cancer initiation and progression | Q29618873 | ||
| TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia | Q29618875 | ||
| Deletion of tuberous sclerosis 1 in somatic cells of the murine reproductive tract causes female infertility | Q30423103 | ||
| Decidual PTEN expression is required for trophoblast invasion in the mouse | Q30429400 | ||
| Dicer is required for female reproductive tract development and fertility in the mouse. | Q30435704 | ||
| Deletion of Dicer in somatic cells of the female reproductive tract causes sterility | Q30438379 | ||
| Somatic LKB1 mutations promote cervical cancer progression | Q33425903 | ||
| Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles | Q33559753 | ||
| Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer | Q33833367 | ||
| Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy | Q33849248 | ||
| From PTEN loss of expression to RICTOR role in smooth muscle differentiation: complex involvement of the mTOR pathway in leiomyosarcomas and pleomorphic sarcomas | Q34232192 | ||
| Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation | Q34527075 | ||
| Frequency and spectrum of cancers in the Peutz-Jeghers syndrome | Q34567595 | ||
| Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin | Q34627013 | ||
| Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas | Q34631135 | ||
| Adenomyoma of the small intestine: report of two cases and review of the literature | Q35067075 | ||
| Cell-specific conditional deletion of Pten in the uterus results in differential phenotypes | Q35113273 | ||
| Rhebbing up mTOR: New Insights on TSC1 and TSC2, and the Pathogenesis of Tuberous Sclerosis | Q35582348 | ||
| Developmental genetics of the female reproductive tract in mammals | Q35590359 | ||
| Laminin production by human endometrial stromal cells relates to the cyclic and pathologic state of the endometrium. | Q35836285 | ||
| Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature | Q36600890 | ||
| Dicer1 is essential for female fertility and normal development of the female reproductive system. | Q37034864 | ||
| Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice. | Q37318625 | ||
| LKB1; linking cell structure and tumor suppression | Q37333592 | ||
| Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity | Q37342290 | ||
| Primary ovarian adenomyoma in a woman with endometrial polyp: a case report and review of the literature | Q37364502 | ||
| Reconstruction of functionally normal and malignant human breast tissues in mice | Q37415657 | ||
| TGFbeta signalling: a complex web in cancer progression | Q37760038 | ||
| Mouse models of uterine corpus tumors: clinical significance and utility. | Q37761988 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 8 | |
| P921 | main subject | sirolimus | Q32089 |
| endometrial cancer | Q944777 | ||
| P304 | page(s) | e1002906 | |
| P577 | publication date | 2012-08-16 | |
| P1433 | published in | PLOS Genetics | Q1893441 |
| P1476 | title | Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1 | |
| P478 | volume | 8 |
| Q36950142 | Conditional deletion of Tsc1 in the female reproductive tract impedes normal oviductal and uterine function by enhancing mTORC1 signaling in mice |
| Q53718488 | Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development. |
| Q50915797 | Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus. |
| Q36059087 | Do hereditary syndrome-related gynecologic cancers have any specific features? |
| Q50529991 | Epithelial Wnt/βcatenin signalling is essential for epididymal coiling. |
| Q36970483 | Germ cell specific overactivation of WNT/βcatenin signalling has no effect on folliculogenesis but causes fertility defects due to abnormal foetal development |
| Q37269300 | Hereditary gynecological tumors associated with Peutz-Jeghers syndrome (Review) |
| Q30370194 | Hyperplasia and fibrosis in mice with conditional loss of the TSC2 tumor suppressor in Müllerian duct mesenchyme-derived myometria. |
| Q48028203 | In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells |
| Q42653992 | Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis |
| Q39026772 | LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies |
| Q37616060 | Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer. |
| Q41179162 | Loss of LKB1 and p53 synergizes to alter fallopian tube epithelial phenotype and high-grade serous tumorigenesis. |
| Q39967050 | Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity |
| Q37662145 | Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions |
| Q37702500 | Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice |
| Q37367677 | PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas |
| Q37118392 | Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy |
| Q34358845 | Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function |
| Q41677991 | Specific deletion of LKB1/Stk11 in the Müllerian duct mesenchyme drives hyperplasia of the periurethral stroma and tumorigenesis in male mice |
| Q47373003 | Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. |
| Q90245099 | Study of the Association of Phosphatase and Tensin Homolog and p27 Expressions in Endometrial Hyperplasia and Carcinoma |
| Q26801412 | Targeting LKB1 in cancer - exposing and exploiting vulnerabilities |
| Q36510070 | Technical challenges and limitations of current mouse models of ovarian cancer |
| Q58093770 | The Emerging Role of the Microenvironment in Endometrial Cancer |
| Q33569721 | The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice |
| Q58704993 | The uterine epithelial loss of Pten is inefficient to induce endometrial cancer with intact stromal Pten |
| Q92107744 | Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells |
| Q38148147 | Unravelling the connection between metabolism and tumorigenesis through studies of the liver kinase B1 tumour suppressor |
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