scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1008382310 |
P356 | DOI | 10.1007/S12016-012-8323-1 |
P698 | PubMed publication ID | 22695942 |
P5875 | ResearchGate publication ID | 225305128 |
P50 | author | M. Eric Gershwin | Q73297886 |
P2093 | author name string | Patrick S C Leung | |
Hajime Tanaka | |||
Christopher L Bowlus | |||
Tom P Kenny | |||
P2860 | cites work | Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 | Q24290619 |
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides | Q24303817 | ||
Senescence of activated stellate cells limits liver fibrosis | Q24621822 | ||
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants | Q24633806 | ||
Liver autoimmunity triggered by microbial activation of natural killer T cells | Q24644772 | ||
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling | Q24647357 | ||
Cellular and molecular mechanisms of fibrosis | Q24648892 | ||
HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases | Q24679388 | ||
Pattern recognition receptors and inflammation | Q27861115 | ||
History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells | Q28190388 | ||
The inhibitory cytokine IL-35 contributes to regulatory T-cell function | Q28258462 | ||
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist | Q28306642 | ||
Liver fibrosis | Q29547449 | ||
Alternative activation of macrophages: mechanism and functions | Q29614350 | ||
Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity | Q29619700 | ||
TLR4 enhances TGF-beta signaling and hepatic fibrosis | Q29620016 | ||
Biology of interleukin-22. | Q30385283 | ||
Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis | Q33214445 | ||
Accelerated and progressive and lethal liver fibrosis in mice that lack interleukin (IL)-10, IL-12p40, and IL-13Rα2. | Q33396838 | ||
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair | Q33565774 | ||
Hepatic stellate cells and the regulation of liver inflammation | Q33799271 | ||
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury | Q33822590 | ||
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response | Q33853821 | ||
Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expression | Q33883569 | ||
Toll-like Receptor 4 and Hepatic Fibrogenesis | Q33905721 | ||
Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis | Q34072530 | ||
Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis | Q34101451 | ||
Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis | Q34116480 | ||
B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis. | Q45957513 | ||
The interleukin-17 pathway is involved in human alcoholic liver disease | Q46141821 | ||
In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset | Q46177088 | ||
Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization | Q46191599 | ||
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer | Q46482007 | ||
Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice | Q46607067 | ||
Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis | Q46714127 | ||
Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3. | Q46742099 | ||
Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis | Q46745228 | ||
AMA production in primary biliary cirrhosis is promoted by the TLR9 ligand CpG and suppressed by potassium channel blockers | Q46872722 | ||
LPS signaling enhances hepatic fibrogenesis caused by experimental cholestasis in mice. | Q46913610 | ||
Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners | Q46939919 | ||
Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC. | Q46974412 | ||
The etiology of liver damage imparts cytokines transforming growth factor beta1 or interleukin-13 as driving forces in fibrogenesis | Q47803510 | ||
Changes in melatonin concentrations during IFN therapy. | Q48736427 | ||
Sustained response to interferon-alpha plus ribavirin therapy for chronic hepatitis C is closely associated with increased dynamism of intrahepatic natural killer and natural killer T cells. | Q50569016 | ||
Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: the serum cytokine profile and peripheral cell population. | Q51757389 | ||
STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. | Q52575315 | ||
Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. | Q53035307 | ||
Impairment of liver regeneration correlates with activated hepatic NKT cells in HBV transgenic mice. | Q53550877 | ||
Hepatic fibrosis 2006: report of the Third AASLD Single Topic Conference. | Q53581215 | ||
Activation of mouse natural killer T cells accelerates liver regeneration after partial hepatectomy. | Q53591552 | ||
Role of TLR9 in hepatic stellate cells and experimental liver fibrosis | Q57083097 | ||
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection | Q59054213 | ||
Angiotensin II induces contraction and proliferation of human hepatic stellate cells | Q61576239 | ||
Granulomas in primary biliary cirrhosis: a prognostic feature | Q70942527 | ||
Isolation of a lipocyte-rich fraction from rat liver nonparenchymal cells | Q72154910 | ||
Primary biliary cirrhosis | Q72331434 | ||
Decrease of CD56(+)T cells and natural killer cells in cirrhotic livers with hepatitis C may be involved in their susceptibility to hepatocellular carcinoma | Q73119472 | ||
Decrease in the prevalence of IL-4-producing CD4+ T cells in patients with advanced stage of primary biliary cirrhosis | Q73292436 | ||
Decreased natural killer cytotoxic activity in chronic alcoholism is associated with alcohol liver disease but not active ethanol consumption | Q73319905 | ||
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells | Q73322874 | ||
Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta | Q73401111 | ||
IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis | Q73869153 | ||
Increased CD1d expression on small bile duct epithelium and epithelioid granuloma in livers in primary biliary cirrhosis | Q77220576 | ||
Chronic ethanol consumption inhibits hepatic natural killer cell activity and accelerates murine cytomegalovirus-induced hepatitis | Q80162138 | ||
Activation-induced cell death of hepatic stellate cells by the innate immune system | Q82529794 | ||
Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing | Q82639999 | ||
Interleukin-15 prevents concanavalin A-induced liver injury in mice via NKT cell-dependent mechanism | Q83856404 | ||
Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis | Q84233203 | ||
A recent perspective on alcohol, immunity, and host defense. | Q37209327 | ||
Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases | Q37326768 | ||
Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis | Q37346066 | ||
Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice | Q37358583 | ||
IL-22: a critical mediator in mucosal host defense | Q37393834 | ||
In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha | Q37403094 | ||
Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride | Q37411006 | ||
Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice | Q37438364 | ||
Hepatic lipocytes: the principal collagen-producing cells of normal rat liver | Q37558514 | ||
Pathogenesis of liver fibrosis | Q37809079 | ||
Role of IL-17 and Th17 cells in liver diseases | Q37825436 | ||
Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis) | Q39859200 | ||
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. | Q40092383 | ||
Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection | Q40495332 | ||
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation | Q40560155 | ||
Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis | Q40668665 | ||
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis. | Q40681279 | ||
Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: implication for a pathogenetic role in alcoholic liver fibrogenesis | Q41228197 | ||
Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis | Q42473784 | ||
Collagen synthesis by human liver (myo)fibroblasts in culture: evidence for a regulatory role of IL-1 beta, IL-4, TGF beta and IFN gamma | Q42513635 | ||
Searching for miR-acles in cardiac fibrosis | Q42560291 | ||
Silencing a killer among us: ethanol impairs immune surveillance of activated stellate cells by natural killer cells | Q43164489 | ||
Biliary cirrhosis in a child with inherited interleukin-12 deficiency | Q43437620 | ||
The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis | Q43785645 | ||
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells | Q43991749 | ||
Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis | Q44047059 | ||
A comparison of fibrosis progression in chronic liver diseases | Q44314885 | ||
Role of Vα 14 NKT cells in the development of impaired liver regeneration in vivo | Q44632301 | ||
Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption | Q44887156 | ||
Accumulating CD57 + CD3 + natural killer T cells are related to intrahepatic bile duct lesions in primary biliary cirrhosis | Q45011633 | ||
Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats | Q45212257 | ||
IL-22 and non-ELR-CXC chemokine expression in chronic hepatitis B virus-infected liver | Q45363028 | ||
Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure | Q45396169 | ||
Production of profibrotic cytokines by invariant NKT cells characterizes cirrhosis progression in chronic viral hepatitis | Q45876518 | ||
IL-17 expression is correlated with hepatitis B‑related liver diseases and fibrosis. | Q45909221 | ||
Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis. | Q45952178 | ||
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3 | Q34163926 | ||
Deaths: final data for 2008. | Q34342648 | ||
Cellular pathophysiology of portal hypertension and prospects for management with gene therapy | Q34374972 | ||
Hepatic blood flow regulation by stellate cells in normal and injured liver | Q34391359 | ||
Hepatic stellate cell behavior during resolution of liver injury | Q34391401 | ||
Transforming growth factor beta and the liver | Q34419491 | ||
Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayer | Q34559156 | ||
Gamma-interferon inhibits collagen synthesis in vivo in the mouse | Q34568345 | ||
Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid | Q34650472 | ||
B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis | Q34669460 | ||
B cell depletion therapy exacerbates murine primary biliary cirrhosis | Q34678839 | ||
PDGF and signal transduction in hepatic stellate cells | Q34754831 | ||
Innate immunity and primary biliary cirrhosis: activated invariant natural killer T cells exacerbate murine autoimmune cholangitis and fibrosis | Q34790985 | ||
Characterization of HCV-specific CD4+Th17 immunity in recurrent hepatitis C-induced liver allograft fibrosis. | Q34795394 | ||
Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis | Q34802178 | ||
Suppression of innate immunity (natural killer cell/interferon-γ) in the advanced stages of liver fibrosis in mice | Q34816420 | ||
Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis | Q35249154 | ||
Hepatic IL-17 responses in human and murine primary biliary cirrhosis | Q35575733 | ||
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ | Q35649446 | ||
Liver fibrosis: from the bench to clinical targets | Q35759110 | ||
Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C. | Q35760543 | ||
Targeted treatments for cirrhosis | Q35911123 | ||
Mechanisms of liver fibrosis | Q36247948 | ||
Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation | Q36291657 | ||
Renal fibrosis: new insights into the pathogenesis and therapeutics | Q36366487 | ||
Toll-like receptor signaling in the liver | Q36477368 | ||
Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses | Q36591648 | ||
Resolving fibrosis in the diseased liver: translating the scientific promise to the clinic. | Q36655445 | ||
Critical contribution of liver natural killer T cells to a murine model of hepatitis | Q36979591 | ||
Liver: An organ with predominant innate immunity | Q37048206 | ||
Interleukin-35: odd one out or part of the family? | Q37073886 | ||
Toll-like receptor signaling in liver regeneration, fibrosis and carcinogenesis | Q37125483 | ||
CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease | Q37155727 | ||
P433 | issue | 3 | |
P921 | main subject | immunology | Q101929 |
P304 | page(s) | 220-229 | |
P577 | publication date | 2012-12-01 | |
P1433 | published in | Clinical Reviews in Allergy & Immunology | Q1932354 |
P1476 | title | Immunological orchestration of liver fibrosis | |
P478 | volume | 43 |
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Q41900346 | Circulating levels of a collagen type v propeptide fragment in a carbon tetrachloride reversible model of liver fibrosis |
Q38565478 | Epigenetics and Primary Biliary Cirrhosis: a Comprehensive Review and Implications for Autoimmunity |
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