| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1047817149 |
| P356 | DOI | 10.1186/S40591-015-0038-2 |
| P932 | PMC publication ID | 4452070 |
| P698 | PubMed publication ID | 26056602 |
| P5875 | ResearchGate publication ID | 276317601 |
| P50 | author | Uros Hladnik | Q56418176 |
| Carlo Riccardo Rossi | Q40058555 | ||
| P2093 | author name string | Daniela Segat | |
| Marco Rastrelli | |||
| Maria Vittoria Enzo | |||
| P2860 | cites work | Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation | Q21195230 |
| Familial adenomatous polyposis | Q21202887 | ||
| Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling | Q24290355 | ||
| R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 | Q24292884 | ||
| A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells | Q24310281 | ||
| Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation | Q24310980 | ||
| A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3 | Q24312935 | ||
| Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling | Q24316697 | ||
| Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins | Q24318774 | ||
| Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer | Q24319963 | ||
| Structural basis of the Axin-adenomatous polyposis coli interaction | Q24594194 | ||
| Activity of Sorafenib against desmoid tumor/deep fibromatosis | Q24620775 | ||
| Wnt/beta-catenin signaling: components, mechanisms, and diseases | Q24630938 | ||
| Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin | Q24630980 | ||
| Wnt signal transduction pathways | Q24641814 | ||
| Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex | Q24646858 | ||
| Cellular and molecular mechanisms of fibrosis | Q24648892 | ||
| Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics | Q24685475 | ||
| Wnt/β-catenin signaling and disease | Q26823272 | ||
| Update on desmoid tumors | Q27002396 | ||
| The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin | Q27631714 | ||
| Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex | Q27640372 | ||
| Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling | Q27675070 | ||
| Three-dimensional structure of the armadillo repeat region of beta-catenin | Q27743283 | ||
| A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. | Q27852131 | ||
| Wnt/beta-catenin signaling in development and disease | Q27860784 | ||
| The Wnt signaling pathway in development and disease | Q27861019 | ||
| Immunity, Inflammation, and Cancer | Q27861048 | ||
| LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation | Q45876077 | ||
| Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb | Q47070747 | ||
| WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra. | Q47827483 | ||
| The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles. | Q50748822 | ||
| Nuclear GSK-3β segregation in desmoid-type fibromatosis. | Q51045139 | ||
| A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling. | Q52607835 | ||
| Genotype-phenotype correlations as a guide in the management of familial adenomatous polyposis. | Q54445038 | ||
| Expression profiles of sex steroid receptors in desmoid tumors. | Q54573348 | ||
| IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. | Q54600671 | ||
| Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment. | Q54731292 | ||
| Optimizing Treatment of Desmoid Tumors | Q57741312 | ||
| Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis | Q64378619 | ||
| Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor) | Q73270781 | ||
| Treatment of extra-abdominal desmoid tumors with interferon-alpha with or without tretinoin | Q73388500 | ||
| Retroperitoneal soft tissue sarcoma: an analysis of radiation and surgical treatment | Q79329247 | ||
| SnapShot: Noncanonical Wnt Signaling Pathways | Q80411299 | ||
| Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions | Q80911947 | ||
| Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoid-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient | Q84729727 | ||
| Downregulation of sFRP-2 by epigenetic silencing activates the β-catenin/Wnt signaling pathway in esophageal basaloid squamous cell carcinoma | Q87165581 | ||
| Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism | Q28114789 | ||
| Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway | Q28118992 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin | Q28205993 | ||
| Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway | Q28217024 | ||
| Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors | Q28247928 | ||
| Mechanistic insights from structural studies of beta-catenin and its binding partners | Q28249766 | ||
| LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way | Q28256465 | ||
| beta-catenin destruction complex: insights and questions from a structural perspective | Q28276987 | ||
| Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction | Q28286117 | ||
| Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients | Q28300256 | ||
| Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta | Q28505773 | ||
| Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin | Q28509692 | ||
| Functional domains of axin. Importance of the C terminus as an oligomerization domain | Q28511342 | ||
| Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions | Q28591541 | ||
| Dynamic recruitment of axin by Dishevelled protein assemblies | Q28592772 | ||
| Planar cell polarity signaling: from fly development to human disease | Q28749129 | ||
| Mechanisms of Wnt signaling in development | Q29547537 | ||
| Wnt signalling in stem cells and cancer | Q29547862 | ||
| Towards an integrated view of Wnt signaling in development | Q29615175 | ||
| WNT signalling pathways as therapeutic targets in cancer | Q29615666 | ||
| Proximal events in Wnt signal transduction | Q29616162 | ||
| Wnt signalling and its impact on development and cancer | Q29619273 | ||
| Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus | Q29620188 | ||
| A new member of the frizzled family from Drosophila functions as a Wingless receptor | Q29620189 | ||
| Identification and characterization of the familial adenomatous polyposis coli gene | Q29620382 | ||
| Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP). | Q30422043 | ||
| Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling | Q33258175 | ||
| The oncogenic activation of beta-catenin | Q33540073 | ||
| Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). | Q33636704 | ||
| Desmoid tumor: prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy | Q33718082 | ||
| Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways | Q33808592 | ||
| Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC/French Sarcoma Group phase II trial with a long-term follow-up | Q34023059 | ||
| Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought. | Q34038265 | ||
| beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds | Q34068062 | ||
| The cadherin-catenin adhesion system in signaling and cancer | Q34124023 | ||
| β-catenin signaling: a novel mediator of fibrosis and potential therapeutic target | Q37925433 | ||
| Tumor promotion via injury- and death-induced inflammation | Q37950602 | ||
| Wnt/beta-catenin signaling: a promising new target for fibrosis diseases. | Q38016472 | ||
| Alternative Wnt pathways and receptors | Q38039332 | ||
| Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies? | Q38151902 | ||
| Genomic insights into WNT/β-catenin signaling | Q38173593 | ||
| Desmoid tumors of the head and neck: a therapeutic challenge | Q38178206 | ||
| Crosstalk between fibroblasts and inflammatory cells | Q38204265 | ||
| Targeting the β-catenin nuclear transport pathway in cancer | Q38211338 | ||
| Anthrax toxin receptor 2a controls mitotic spindle positioning | Q38319622 | ||
| Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target | Q38332803 | ||
| Immunohistochemical and mutational analysis of PDGF and PDGFR in desmoid tumours: is there a role for tyrosine kinase inhibitors in c-kit-negative desmoid tumours? | Q38434898 | ||
| Analysis of TGF-beta protein expression in aggressive fibromatosis (desmoid tumor). | Q38435863 | ||
| Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. | Q38756671 | ||
| Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme | Q38982747 | ||
| Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury. | Q38988284 | ||
| β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency | Q39057098 | ||
| Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway. | Q39087896 | ||
| AXIN genetic analysis in adrenocortical carcinomas updated | Q39133079 | ||
| Functional dissection of phosphorylation of Disheveled in Drosophila | Q39277833 | ||
| Desmoid: the role of local therapy in an era of systemic options. | Q39403331 | ||
| APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC. | Q39526100 | ||
| APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase. | Q39908039 | ||
| Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta | Q39966655 | ||
| DKK1 antagonizes Wnt signaling without promotion of LRP6 internalization and degradation | Q39978358 | ||
| Nuclear GSK-3beta inhibits the canonical Wnt signalling pathway in a beta-catenin phosphorylation-independent manner. | Q40020092 | ||
| Toremifene decreases type I, type II and increases type III receptors in desmoid and fibroma and inhibits TGFbeta1 binding in desmoid fibroblasts. | Q40031675 | ||
| Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. | Q40036004 | ||
| TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations | Q40113599 | ||
| Synthesis and secretion of transforming growth factor-beta1 by human desmoid fibroblast cell line and its modulation by toremifene. | Q40762687 | ||
| Hyperthermic isolated limb perfusion with tumor necrosis factor-alpha and melphalan in advanced soft-tissue sarcomas: histopathological considerations | Q40770055 | ||
| The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. | Q40967633 | ||
| The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization | Q41791636 | ||
| Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway | Q42234880 | ||
| Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. | Q42431545 | ||
| Regulation of β-catenin nuclear dynamics by GSK-3β involves a LEF-1 positive feedback loop | Q42811839 | ||
| Common peroneal nerve palsy following TNF-based isolated limb perfusion for irresectable extremity desmoid tumor | Q43234343 | ||
| Extended follow-up of patients treated with cytotoxic chemotherapy for intra-abdominal desmoid tumors | Q43754908 | ||
| Response of extraabdominal desmoid tumors to therapy with imatinib mesylate | Q44219701 | ||
| Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. | Q34289010 | ||
| An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells | Q34367476 | ||
| The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity | Q34455099 | ||
| The pharmacological treatment of aggressive fibromatosis: a systematic review | Q34530981 | ||
| Wnt signaling pathway pharmacogenetics in non-small cell lung cancer | Q34543360 | ||
| Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors. | Q34597947 | ||
| Multimodality management of desmoid tumors: how important is a negative surgical margin? | Q34601736 | ||
| CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression | Q34627193 | ||
| Signal transduction pathway analysis in desmoid-type fibromatosis: transforming growth factor-β, COX2 and sex steroid receptors | Q34643472 | ||
| The WNT signalling pathway and diabetes mellitus | Q34807472 | ||
| Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma | Q34976628 | ||
| The wound healing process: an overview of the cellular and molecular mechanisms | Q35014036 | ||
| High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. | Q35049311 | ||
| The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling | Q35124049 | ||
| Immunohistochemical analysis of desmoid tumours | Q35588802 | ||
| Can we safely target the WNT pathway? | Q35591995 | ||
| Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity | Q35763147 | ||
| Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis | Q35863725 | ||
| The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled | Q35959511 | ||
| CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling | Q36397808 | ||
| Post-traumatic soft tissue tumors: case report and review of the literature a propos a post-traumatic paraspinal desmoid tumor. | Q36502467 | ||
| LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. | Q36567999 | ||
| Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target | Q36673270 | ||
| Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility | Q36710748 | ||
| Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling. | Q36725106 | ||
| Wnt/beta-catenin signaling in cancer stemness and malignant behavior | Q36738603 | ||
| Planar polarity and tissue morphogenesis | Q36851258 | ||
| Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling | Q36945923 | ||
| Phospho-regulation of Beta-catenin adhesion and signaling functions. | Q36967628 | ||
| Wnt signaling | Q37020455 | ||
| Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila. | Q37146876 | ||
| Selective activation mechanisms of Wnt signaling pathways | Q37390097 | ||
| β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis | Q37634132 | ||
| Wnt signaling and colon carcinogenesis: beyond APC. | Q37864083 | ||
| P304 | page(s) | 1 | |
| P577 | publication date | 2015-01-30 | |
| P1433 | published in | Molecular and cellular therapies | Q27725367 |
| P1476 | title | The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target | |
| P478 | volume | 3 |
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| Q64989078 | Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review. |
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