review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1029766632 |
P356 | DOI | 10.1038/NATURE03319 |
P3181 | OpenCitations bibliographic resource ID | 141884 |
P698 | PubMed publication ID | 15829953 |
P5875 | ResearchGate publication ID | 7907046 |
P2093 | author name string | Clevers H | |
Reya T | |||
P2860 | cites work | Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia | Q22010579 |
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling | Q24290355 | ||
Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2 | Q24307092 | ||
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly | Q24312910 | ||
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells | Q24314491 | ||
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma | Q24336272 | ||
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells | Q24568035 | ||
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
Stem cells, cancer, and cancer stem cells | Q27860878 | ||
A common human skin tumour is caused by activating mutations in beta-catenin | Q28115245 | ||
Lessons from hereditary colorectal cancer | Q28131788 | ||
Regulation of LEF-1/TCF transcription factors by Wnt and other signals | Q28141939 | ||
The Hedgehog and Wnt signalling pathways in cancer | Q28189485 | ||
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin | Q28190343 | ||
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation | Q28200070 | ||
Wnt activates the Tak1/Nemo-like kinase pathway | Q28244920 | ||
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate | Q28287796 | ||
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis | Q28506650 | ||
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB | Q28508041 | ||
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1 | Q28513432 | ||
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism | Q28585177 | ||
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration | Q28587140 | ||
Deletion of β-catenin impairs T cell development | Q28587501 | ||
A role for Wnt signalling in self-renewal of haematopoietic stem cells | Q28592213 | ||
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 | Q28592260 | ||
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML | Q29614278 | ||
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor | Q29614622 | ||
Osteoblastic cells regulate the haematopoietic stem cell niche | Q29615007 | ||
Identification of the haematopoietic stem cell niche and control of the niche size | Q29615008 | ||
Wnt proteins are lipid-modified and can act as stem cell growth factors | Q29615009 | ||
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors | Q29615158 | ||
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin | Q29616492 | ||
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice | Q29618462 | ||
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling | Q29619294 | ||
A molecular profile of a hematopoietic stem cell niche | Q30847561 | ||
The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells | Q33199519 | ||
Translating stem and progenitor cell biology to the clinic: barriers and opportunities | Q33846149 | ||
Gut instincts: thoughts on intestinal epithelial stem cells | Q33936387 | ||
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless | Q34166322 | ||
A direct measurement of the radiation sensitivity of normal mouse bone marrow cells | Q34249472 | ||
Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells | Q34253556 | ||
The multifaceted Paneth cell | Q34531936 | ||
Designer skin: lineage commitment in postnatal epidermis | Q34616032 | ||
WNT signaling and lymphocyte development | Q34619783 | ||
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells | Q34792452 | ||
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. | Q34870182 | ||
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. | Q35079614 | ||
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. | Q35122385 | ||
Revisiting the bulge | Q35739842 | ||
Wnt signaling in the stem cell niche | Q35838139 | ||
Signaling pathways in intestinal development and cancer | Q35912854 | ||
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice | Q36294220 | ||
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis | Q36399011 | ||
Use of transgenic mice to infer the biological properties of small intestinal stem cells and to examine the lineage relationships of their descendants | Q37610716 | ||
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. | Q38343552 | ||
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium | Q39895829 | ||
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer | Q40664922 | ||
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling | Q40690911 | ||
Wnt signaling regulates hemopoiesis through stromal cells. | Q40794241 | ||
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling | Q40844523 | ||
Stem cells in gastrointestinal epithelium: numbers, characteristics and death | Q40849001 | ||
Epithelial cell migration in the intestine | Q40950314 | ||
The complement of desmosomal plaque proteins in different cell types | Q41491027 | ||
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system | Q44472635 | ||
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis | Q44572857 | ||
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling | Q45065876 | ||
Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells. | Q47247972 | ||
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours | Q47764649 | ||
AXIN1 mutations but not deletions in cerebellar medulloblastomas | Q48399835 | ||
Wnt proteins promote neuronal differentiation in neural stem cell culture. | Q51725683 | ||
Clonal analysis of mouse intestinal epithelial progenitors. | Q53940112 | ||
An HMG-box-containing T-cell factor required for thymocyte differentiation. | Q59058515 | ||
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells | Q75236410 | ||
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue | Q79358419 | ||
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance | Q81308407 | ||
P433 | issue | 7035 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Wnt signaling pathway | Q155769 |
P304 | page(s) | 843-50 | |
P577 | publication date | 2005-04-14 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Wnt signalling in stem cells and cancer | |
P478 | volume | 434 |
Q37279574 | "Cancer stem cells"-lessons from Hercules to fight the Hydra |
Q90568982 | (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations |
Q46030038 | 1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/β-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M |
Q36293864 | 2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway |
Q36755060 | 3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). |
Q51623514 | 4.1N is involved in a flotillin-1/β-catenin/Wnt pathway and suppresses cell proliferation and migration in non-small cell lung cancer cell lines. |
Q46023360 | 5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model. |
Q51758439 | A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells. |
Q37213583 | A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin |
Q21284963 | A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver |
Q47578090 | A Multicellular Model of Intestinal Crypt Buckling and Fission |
Q35637029 | A Multiscale Model Evaluates Screening for Neoplasia in Barrett's Esophagus |
Q39155018 | A New View of Pathway-Driven Drug Resistance in Tumor Proliferation |
Q41423837 | A Reciprocal Interaction between β-Catenin and Osterix in Cementogenesis |
Q24310281 | A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells |
Q40163505 | A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein. |
Q57709818 | A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects |
Q34987904 | A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression. |
Q24318611 | A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5) |
Q38123757 | A commentary on iPS cells: potential applications in autologous transplantation, study of illnesses and drug screening |
Q35095530 | A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells |
Q35320560 | A decline in Wnt3a signaling is necessary for mesenchymal stem cells to proceed to replicative senescence |
Q33646860 | A direct protein-protein interaction is involved in the suppression of beta-catenin transcription by retinoid X receptor alpha in colorectal cancer cells |
Q53627022 | A dishevelled-1/Smad1 interaction couples WNT and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells. |
Q47143821 | A framework to find the logic backbone of a biological network. |
Q24644948 | A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer |
Q40181009 | A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways. |
Q36275692 | A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules |
Q52594760 | A multi-arm phase I dose escalating study of an oral NOTCH inhibitor BMS-986115 in patients with advanced solid tumours. |
Q33418420 | A multiple timescale analysis of a mathematical model of the Wnt/beta-catenin signalling pathway |
Q25257330 | A new description of cellular quiescence |
Q34589167 | A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1 |
Q30370900 | A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling. |
Q37571904 | A novel matrine derivate inhibits differentiated human hepatoma cells and hepatic cancer stem-like cells by suppressing PI3K/AKT signaling pathways |
Q41931798 | A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis |
Q89558582 | A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration |
Q58164878 | A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth |
Q90002280 | A positive feedback loop of β-catenin/CCR2 axis promotes regorafenib resistance in colorectal cancer |
Q31031951 | A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker |
Q34360413 | A reaction-diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts |
Q38008209 | A review of spatial computational models for multi-cellular systems, with regard to intestinal crypts and colorectal cancer development |
Q37161227 | A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway |
Q37039541 | A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription |
Q33522055 | A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates |
Q33552287 | A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation |
Q34284702 | A systems biology approach reveals common metastatic pathways in osteosarcoma |
Q33478377 | A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis |
Q34609728 | A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins |
Q27330614 | A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath |
Q37421928 | A van der Waals-like Transition Between Normal and Cancerous Phases in Cell Populations Dynamics of Colorectal Cancer |
Q34532074 | AF10 plays a key role in the survival of uncommitted hematopoietic cells |
Q35581875 | ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways |
Q36095333 | ALEX1 may be a novel biomarker for human cervical squamous cell carcinoma |
Q47149287 | ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis. |
Q28115305 | ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma |
Q37036357 | ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epithelia |
Q91861032 | ASPM promotes prostate cancer stemness and progression by augmenting Wnt-Dvl-3-β-catenin signaling |
Q26738411 | Aberrant Wnt Signaling in Leukemia |
Q39387696 | Aberrant Wnt signaling: a special focus in CNS diseases |
Q37499259 | Aberrant activation of the WNT/β-catenin signaling pathway in lupus nephritis |
Q39238680 | Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells |
Q53161614 | Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice. |
Q64056790 | Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells |
Q36351067 | Activation and Inhibition of The Wnt3A Signaling Pathway in Buffalo (Bubalus bubalis) Embryonic Stem Cells: Effects of WNT3A, Bio and Dkk1 |
Q99417970 | Activation of Wnt signaling by amniotic fluid stem cell-derived extracellular vesicles attenuates intestinal injury in experimental necrotizing enterocolitis |
Q37228472 | Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma |
Q30354724 | Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging. |
Q28580415 | Activation of beta-catenin in the stem cell region of crypts during growth of the small intestine in infant rats |
Q30383554 | Activation of endothelial β-catenin signaling induces heart failure. |
Q34178515 | Activation of the Wnt pathway through Wnt2 promotes metastasis in pancreatic cancer |
Q39261852 | Activation of β-catenin signaling is critical for doxorubicin-induced epithelial-mesenchymal transition in BGC-823 gastric cancer cell line |
Q34211879 | Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse |
Q51340061 | Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation. |
Q34044380 | Active Wnt signaling in response to cardiac injury |
Q39290765 | Adamantinomatous craniopharyngiomas express tumor stem cell markers in cells with activated Wnt signaling: further evidence for the existence of a tumor stem cell niche? |
Q54337186 | Additional chromosomal abnormalities detected by array comparative genomic hybridization in AML. |
Q34100145 | Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium |
Q37341011 | Adhesion proteins meet receptors: a common theme? |
Q35622172 | Adipocyte activation of cancer stem cell signaling in breast cancer |
Q84654667 | Administration of embryonic stem cells generates effective antitumor immunity in mice with minor and heavy tumor load |
Q35783155 | Adrenocortical cells with stem/progenitor cell properties: recent advances |
Q38204976 | Adult neurogenesis and glial oncogenesis: when the process fails. |
Q100945769 | Advances in targeted therapy mainly based on signal pathways for nasopharyngeal carcinoma |
Q37575251 | Aging increases CCN1 expression leading to muscle senescence |
Q27323158 | Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signalling |
Q36065109 | Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation |
Q48240016 | Alcohol Injury Damages Intestinal Stem Cells |
Q35033149 | Alkyloxy carbonyl modified hexapeptides as a high affinity compounds for Wnt5A protein in the treatment of psoriasis. |
Q39956183 | Alpha2beta1 integrin regulates lineage commitment in multipotent human colorectal cancer cells |
Q38287571 | Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts |
Q38743931 | Altered homeostatic regulation of innate and adaptive immunity in lower gastrointestinal tract GVHD pathogenesis |
Q33507522 | Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes |
Q53211105 | Alternative splicing within the Wnt signaling pathway: role in cancer development. |
Q35818227 | An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype |
Q38960008 | An approach to infer putative disease-specific mechanisms using neighboring gene networks |
Q34807998 | An atypical age-specific pattern of hepatocellular carcinoma in Peru: a threat for Andean populations |
Q41322926 | An embryonic system to assess direct and indirect Wnt transcriptional targets |
Q37965746 | An evolving web of signaling networks regulated by Cripto-1. |
Q35829857 | An integrated gene regulatory network controls stem cell proliferation in teeth |
Q36959265 | An integrated, directed mass spectrometric approach for in-depth characterization of complex peptide mixtures |
Q34548844 | An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle |
Q37345126 | An update on the biology of cancer stem cells in breast cancer |
Q57809044 | An update on the role of RANKL-RANK/osteoprotegerin and WNT-ß-catenin signaling pathways in pediatric diseases |
Q37727184 | Analysis of NF-kappaB signaling pathways by proteomic approaches |
Q36845050 | Animal models of GWAS-identified type 2 diabetes genes |
Q50047971 | Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells. |
Q37119310 | Antitumor effect of embryonic stem cells in a non-small cell lung cancer model: antitumor factors and immune responses |
Q40676032 | Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II. |
Q39045827 | Apicidin-resistant HA22T hepatocellular carcinoma cells strongly activated the Wnt/β-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway enhancing cell metastatic effect |
Q34346968 | Apoptosis, stem cells, and tissue regeneration |
Q39095223 | Array analysis for potential biomarker of gemcitabine identification in non-small cell lung cancer cell lines |
Q37304164 | Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands |
Q46014740 | Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence. |
Q51761835 | At the Crossroads Between Neurodegeneration and Cancer: A Review of Overlapping Biology and Its Implications. |
Q39016335 | Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. |
Q41100719 | Autophagy gets in on the regulatory act. |
Q39338968 | Autophagy is active in normal colon mucosa |
Q39678666 | Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation |
Q28274105 | Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network |
Q37283834 | Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling |
Q38613512 | Axin1 up-regulated 1 accelerates stress-induced cardiomyocytes apoptosis through activating Wnt/β-catenin signaling |
Q90456889 | Axin2 overexpression promotes the early epithelial disintegration and fusion of facial prominences during avian lip development |
Q47850510 | Axin2-mTurquoise2: A novel reporter mouse model for the detection of canonical Wnt signalling. |
Q55429255 | B-1 cells and B-1 cell precursors prompt different responses to Wnt signaling. |
Q36453561 | BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties |
Q37084834 | BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling |
Q39583314 | BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells |
Q36446479 | BRCA1 regulates human mammary stem/progenitor cell fate |
Q24298234 | Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation |
Q64926713 | Berberine improves advanced glycation end products‑induced osteogenic differentiation responses in human periodontal ligament stem cells through the canonical Wnt/β‑catenin pathway. |
Q28590588 | Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis |
Q40006362 | Beta-catenin interacts with MyoD and regulates its transcription activity |
Q80622205 | Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells |
Q36193130 | Beta-catenin, cancer, and G proteins: not just for frizzleds anymore |
Q35049230 | Beta-catenin/HuR post-transcriptional machinery governs cancer stem cell features in response to hypoxia |
Q36857760 | Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs |
Q28279788 | Beyond tumorigenesis: cancer stem cells in metastasis |
Q46453183 | Bidirectional Regulation of Mouse Embryonic Stem Cell Proliferation by Nicotine Is Mediated Through Wnt Signaling Pathway |
Q38028240 | Biochemistry of epidermal stem cells |
Q36510510 | Biological principles for ex vivo adult stem cell expansion |
Q34880119 | Biology-oriented synthesis of a natural-product inspired oxepane collection yields a small-molecule activator of the Wnt-pathway |
Q35131282 | Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling |
Q36977544 | Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway |
Q28390867 | Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses |
Q37736204 | Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype |
Q38730840 | Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling |
Q54661267 | Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice. |
Q33778512 | Bone marrow mesenchymal stem cell-derived Wnt5a inhibits leukemia cell progression in vitro via activation of the non-canonical Wnt signaling pathway |
Q33834902 | Bone mass is inversely proportional to Dkk1 levels in mice |
Q34030601 | Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours |
Q38066205 | Bone morphogenetic proteins in craniofacial surgery: current techniques, clinical experiences, and the future of personalized stem cell therapy |
Q36402226 | Bone-marrow haematopoietic-stem-cell niches |
Q41193440 | Brachyury establishes the embryonic mesodermal progenitor niche |
Q80292094 | Brain tumor stem cells |
Q36488721 | Brain tumour stem cells |
Q36740051 | Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells |
Q37300676 | Breast cancer stem cells and tumor suppressor genes |
Q35001086 | Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks |
Q36684373 | Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling |
Q33926141 | CBP/catenin antagonist safely eliminates drug-resistant leukemia-initiating cells |
Q50053330 | CD133 expression and α-fetoprotein levels define novel prognostic subtypes of HBV-associated hepatocellular carcinoma: A long-term follow-up analysis. |
Q37541830 | CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer |
Q36414685 | CDX2 is an amplified lineage-survival oncogene in colorectal cancer |
Q38993980 | CKAP4 inhibited growth and metastasis of hepatocellular carcinoma through regulating EGFR signaling |
Q42230688 | CKAP4 is identified as a receptor for Dickkopf in cancer cells |
Q33974636 | CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder |
Q47938594 | CREPT and p15RS regulate cell proliferation and cycling in chicken DF-1 cells through the Wnt/β-catenin pathway. |
Q34044544 | CREPT/RPRD1B, a recently identified novel protein highly expressed in tumors, enhances the β-catenin·TCF4 transcriptional activity in response to Wnt signaling |
Q34176395 | CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer |
Q27310305 | CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4 |
Q36644748 | CTNNB1, AXIN1 and APC expression analysis of different medulloblastoma variants |
Q33411752 | Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools |
Q38702814 | Cadmium stimulates metastasis-associated phenotype in triple-negative breast cancer cells through integrin and β-catenin signaling |
Q38270188 | Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification |
Q52610754 | Calcium as a signal integrator in developing epithelial tissues. |
Q37659196 | Can colorectal cancer be prevented or treated by oral hormone replacement therapy? |
Q27022017 | Can nanomedicines kill cancer stem cells? |
Q39773200 | Cancer Stem Cells and Pediatric Solid Tumors |
Q90103132 | Cancer Stem Cells and Stem Cell Tumors in Drosophila |
Q38808963 | Cancer Stem Cells: Formidable Allies of Cancer |
Q27024816 | Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment |
Q43251364 | Cancer and aging: the molecular pathways |
Q35756082 | Cancer biology: a new RING to Wnt signaling |
Q55416886 | Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification. |
Q47130831 | Cancer cell-soluble factors reprogram mesenchymal stromal cells to slow cycling, chemoresistant cells with a more stem-like state. |
Q47313086 | Cancer driver G-protein coupled receptor (GPCR) induced β-catenin nuclear localization: the transcriptional junction |
Q42006656 | Cancer stem cell markers in head and neck squamous cell carcinoma. |
Q36608674 | Cancer stem cell phenotype is supported by secretory phospholipase A2 in human lung cancer cells |
Q26779931 | Cancer stem cell targeted therapy: progress amid controversies. |
Q37920789 | Cancer stem cell theory in gastrointestinal malignancies: recent progress and upcoming challenges |
Q41868891 | Cancer stem cell, niche and EGFR decide tumor development and treatment response: A bio-computational simulation study |
Q84976114 | Cancer stem cells |
Q33254002 | Cancer stem cells - new and potentially important targets for the therapy of oral squamous cell carcinoma |
Q37841186 | Cancer stem cells and cancer therapy |
Q37630181 | Cancer stem cells and hepatocellular carcinoma |
Q37114128 | Cancer stem cells and human malignant melanoma |
Q33614696 | Cancer stem cells and their mechanism of chemo-radiation resistance |
Q36698757 | Cancer stem cells and their role in metastasis |
Q34048047 | Cancer stem cells in Helicobacter pylori infection and aging: Implications for gastric carcinogenesis |
Q37634973 | Cancer stem cells in glioma: challenges and opportunities |
Q33349066 | Cancer stem cells in solid tumors: elusive or illusive? |
Q28293535 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions |
Q37913359 | Cancer stem cells in the human mammary gland and regulation of their differentiation by estrogen. |
Q49557760 | Cancer stem cells revisited. |
Q38881450 | Cancer stem cells: progress and challenges in lung cancer |
Q37861207 | Cancer stem cells: the development of new cancer therapeutics. |
Q38967885 | Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition |
Q27307633 | Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis |
Q37209758 | Cancer, stem cells, and oncolytic viruses |
Q37323724 | Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling |
Q36602083 | Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage |
Q51961403 | Canonical WNT/beta-catenin signaling is required for ureteric branching. |
Q51922368 | Canonical Wnt signaling activity during synovial joint development. |
Q39212535 | Canonical Wnt signaling induces a primitive endoderm metastable state in mouse embryonic stem cells |
Q35865003 | Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors |
Q37405722 | Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells |
Q28510525 | Canonical Wnt signaling negatively regulates platelet function |
Q34808697 | Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration |
Q24813918 | Canonical Wnt signaling: high-throughput RNAi widens the path |
Q34974487 | Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells |
Q28510103 | Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance |
Q89782897 | Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/β-catenin Signaling in Human Oral Mucosa Stem Cells |
Q28245461 | Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity |
Q37611657 | Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway |
Q90193154 | Cell Heterogeneity and Phenotypic Plasticity in Metastasis Formation: The Case of Colon Cancer |
Q24294429 | Cell cycle control of wnt receptor activation |
Q35139005 | Cell differentiation along multiple pathways accompanied by changes in histone acetylation status |
Q40630464 | Cell proliferation in cutaneous malignant melanoma: relationship with neoplastic progression |
Q33841725 | Cell-autonomous beta-catenin signaling regulates cortical precursor proliferation |
Q27022532 | Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials |
Q49292906 | Cell-type specific potent Wnt signaling blockade by bispecific antibody. |
Q64990280 | Cellular Interactions in the Intestinal Stem Cell Niche. |
Q28251880 | Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder |
Q37077418 | Cellular quiescence in mammary stem cells and breast tumor stem cells: got testable hypotheses? |
Q28651049 | Cetaceans evolution: insights from the genome sequences of common minke whales |
Q33769672 | Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review). |
Q89519650 | Changes in the expression of Notch and Wnt signalling molecules in human endometrial cancer |
Q33564920 | Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4. |
Q34203737 | Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker |
Q33631227 | Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling |
Q42396920 | Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism |
Q30431314 | Chemical approaches to stem cell biology and therapeutics |
Q39236963 | Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling. |
Q82747382 | Chromatin code, local non-equilibrium dynamics, and the emergence of transcription regulatory programs |
Q36988886 | Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells |
Q90707564 | Chromatin regulation and dynamics in stem cells |
Q37579448 | Chronic exposure of renal stem cells to inorganic arsenic induces a cancer phenotype |
Q49344588 | Circuit Design Features of a Stable Two-Cell System. |
Q37467572 | Cisplatin and TRAIL enhance breast cancer stem cell death |
Q64923110 | Clinical Significance of Transcription Factor 7 (TCF7) as a Prognostic Factor in Gastric Cancer. |
Q33669921 | Clinical Usefulness of Serum CYFRA 21-1 in Patients with Colorectal Cancer |
Q38026464 | Clinical implication of targeting of cancer stem cells |
Q48351294 | Clinical significance of epithelial-to-mesenchymal transition in laryngeal carcinoma: Its role in the different subsites. |
Q50955886 | Clinical significance of lymphoid enhancer-binding factor 1 expression in acute myeloid leukemia. |
Q35040935 | Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients |
Q45786900 | Co-activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer |
Q60050019 | Co-treatment of tumor cells with hyaluronan plus doxorubicin affects endothelial cell behavior independently of VEGF expression |
Q36319940 | Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation |
Q41860950 | Colon Cancer Stem Cells: Bench-to-Bedside-New Therapeutical Approaches in Clinical Oncology for Disease Breakdown. |
Q28391219 | Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture |
Q42277641 | Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy |
Q28222785 | Colorectal cancer prevention: choosing the most effective population strategy using bio-mathematical approaches |
Q35597715 | Colorectal cancer prognosis: is it all mutation, mutation, mutation? |
Q37962652 | Colorectal cancer stem cell: a potential therapeutic target |
Q37183760 | Colorectal carcinogenesis: Review of human and experimental animal studies |
Q92173125 | Combination of the natural compound Periplocin and TRAIL induce esophageal squamous cell carcinoma apoptosis in vitro and in vivo: Implication in anticancer therapy |
Q47141878 | Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis |
Q39044438 | Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction |
Q35189046 | Comparing a discrete and continuum model of the intestinal crypt |
Q37215425 | Comparison of Osteogenesis between Adipose-Derived Mesenchymal Stem Cells and Their Sheets on Poly-ε-Caprolactone/β-Tricalcium Phosphate Composite Scaffolds in Canine Bone Defects |
Q36010516 | Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer |
Q33869158 | Complex interactions between GSK3 and aPKC in Drosophila embryonic epithelial morphogenesis |
Q55476361 | Composite Scaffolds Based on Intestinal Extracellular Matrices and Oxidized Polyvinyl Alcohol: A Preliminary Study for a New Regenerative Approach in Short Bowel Syndrome. |
Q34063075 | Computational analysis of expression of human embryonic stem cell-associated signatures in tumors. |
Q50123249 | Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment. |
Q36515815 | Conditional switches for extracellular matrix patterning in Drosophila melanogaster |
Q43167823 | Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow |
Q26785528 | Connections between cadherin-catenin proteins, spindle misorientation, and cancer |
Q55462530 | Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin. |
Q34071276 | Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations |
Q35746042 | Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors |
Q47310367 | Constructing cellular niche properties by localized presentation of Wnt proteins on synthetic surfaces. |
Q64089643 | Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis |
Q52903652 | Contribution of EVX1 in Aggressiveness of Esophageal Squamous Cell Carcinoma. |
Q34541595 | Contribution of TIP30 to chemoresistance in laryngeal carcinoma |
Q37980722 | Controlling the stem cell compartment and regeneration in vivo: the role of pluripotency pathways |
Q37552660 | Controversies in cancer stem cells: targeting embryonic signaling pathways |
Q35543017 | Convergence of 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A and glycogen synthase kinase-3beta/beta-catenin signaling in corpus luteum progesterone synthesis |
Q35906261 | Cooperation between Wnt and Notch signalling in human breast cancer. |
Q39865463 | Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains |
Q39301953 | Coordinated action of hypoxia-inducible factor-1α and β-catenin in androgen receptor signaling |
Q37571557 | Copy number variation of the APC gene is associated with regulation of bone mineral density |
Q42091512 | Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma. |
Q36428279 | Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors. |
Q52715797 | Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis. |
Q34677454 | Crosstalk of Oncogenic Signaling Pathways during Epithelial-Mesenchymal Transition |
Q36790604 | Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells |
Q27650057 | Crystal Structure of a Full-Length β-Catenin |
Q27677080 | Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment |
Q27674857 | Crystal structures of the extracellular domain of LRP6 and its complex with DKK1 |
Q62698534 | Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling |
Q41670781 | Curcumin reduces mitomycin C resistance in breast cancer stem cells by regulating Bcl-2 family-mediated apoptosis |
Q52679071 | Current Insights into Oral Cancer Epigenetics. |
Q39995485 | Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling |
Q38101024 | Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter |
Q36903109 | DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer. |
Q57753463 | DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene |
Q38913352 | DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis |
Q35624893 | DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo |
Q53508275 | DNA Hypermethylation of SHISA3 in Colorectal Cancer: An Independent Predictor of Poor Prognosis. |
Q53830978 | DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features. |
Q37276254 | DOXIL when combined with Withaferin A (WFA) targets ALDH1 positive cancer stem cells in ovarian cancer |
Q24302441 | Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation |
Q24329167 | Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus |
Q79777489 | Darwinian medicine: a case for cancer |
Q24657713 | Dazap2 modulates transcription driven by the Wnt effector TCF-4 |
Q36927321 | Declaration of patent applications as financial interests: a survey of practice among authors of papers on molecular biology in Nature |
Q39732013 | Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth |
Q35695511 | Dedifferentiation of patient-derived glioblastoma multiforme cell lines results in a cancer stem cell-like state with mitogen-independent growth |
Q30447391 | Deep tissue fluorescence imaging and in vivo biological applications |
Q34700590 | Defective osteogenic differentiation in the development of osteosarcoma |
Q39904972 | Defensin-immunology in inflammatory bowel disease |
Q33891944 | Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells |
Q36251554 | Defining the molecular nexus of cancer, type 2 diabetes and cardiovascular disease |
Q36821221 | Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity. |
Q34228323 | Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading |
Q55088439 | Demyelination in Multiple Sclerosis: Reprogramming Energy Metabolism and Potential PPARγ Agonist Treatment Approaches. |
Q52629170 | Depleting ovarian cancer stem cells with calcitriol. |
Q42802134 | Depletion of tumor suppressor Kank1 induces centrosomal amplification via hyperactivation of RhoA. |
Q38588880 | Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia. |
Q40088682 | Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification |
Q36176784 | Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis. |
Q35110734 | Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD). |
Q24318750 | Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling |
Q36672276 | Development and differentiation of neural rosettes derived from human embryonic stem cells |
Q26781898 | Development of anticancer agents targeting the Wnt/β-catenin signaling |
Q26739045 | Developmental Drift and the Role of Wnt Signaling in Aging |
Q51951704 | Developmental biology: Our fly cousins' gut. |
Q37000634 | Developmental signaling pathways in brain tumor-derived stem-like cells. |
Q26766266 | Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer |
Q38824254 | Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog |
Q35544524 | Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis |
Q39897131 | Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population |
Q48148598 | Developmentally regulated signaling pathways in glioma invasion. |
Q33829495 | Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer |
Q39459014 | Dickkopf 4 positively regulated by the thyroid hormone receptor suppresses cell invasion in human hepatoma cells |
Q64999289 | Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression. |
Q34018958 | Dickkopf1 regulates fate decision and drives breast cancer stem cells to differentiation: an experimentally supported mathematical model |
Q47753175 | Dietary Regulation of Adult Stem Cells. |
Q37728998 | Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-Regulation |
Q35106746 | Different requirements for Wnt signaling in tongue myogenic subpopulations |
Q36652783 | Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells |
Q42469771 | Differential expression of basal microRNAs' patterns in human dental pulp stem cells |
Q54294158 | Differential gene expression of Wnt signaling pathway in benign, premalignant, and malignant human breast epithelial cells. |
Q92354388 | Differential regulation of myc homologs by Wnt/β-Catenin signaling in the early metazoan Hydra |
Q50216018 | Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts. |
Q34249028 | Differentiated epidermal cells regain the ability to regenerate a skin equivalent by increasing the level of β-catenin in the cells |
Q52622302 | Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer. |
Q33889275 | Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept |
Q98505940 | Differentiation of cancer stem cells using synthetic small molecules: toward new therapeutic strategies against therapy resistance |
Q50778004 | Diffusion- and convection-based activation of Wnt/β-catenin signaling in a gradient generating microfluidic chip. |
Q34506361 | Dimethyloxalylglycine prevents bone loss in ovariectomized C57BL/6J mice through enhanced angiogenesis and osteogenesis |
Q38989123 | Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β. |
Q34182342 | Discovering dysfunction of multiple microRNAs cooperation in disease by a conserved microRNA co-expression network |
Q58762810 | Discovery of Potent Disheveled/Dvl Inhibitors Using Virtual Screening Optimized With NMR-Based Docking Performance Index |
Q39081836 | Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection |
Q36582366 | Diseases of Wnt signaling |
Q35587229 | Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas |
Q38737124 | Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia |
Q33763825 | Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA. |
Q37706466 | Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway |
Q38015669 | Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments |
Q35653963 | Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia |
Q49937490 | Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors. |
Q40219129 | Distinct nuclear arrangement of active and inactive c-myc genes in control and differentiated colon carcinoma cells |
Q38634944 | Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells. |
Q35641656 | Dormant Wnt-initiated mammary cancer can participate in reconstituting functional mammary glands |
Q53589257 | Down-regulation of Frizzled-7 expression inhibits migration, invasion, and epithelial-mesenchymal transition of cervical cancer cell lines. |
Q92803223 | Down-regulation of SLC35C1 induces colon cancer through over-activating Wnt pathway |
Q64057521 | Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus |
Q43068054 | Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway |
Q64068495 | Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma |
Q35237732 | Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines |
Q41387605 | Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells |
Q39149024 | Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas |
Q97537814 | Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles |
Q37840943 | Drug discovery approaches to target Wnt signaling in cancer stem cells |
Q28473512 | Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties |
Q38012254 | Drugging Wnt signalling in cancer |
Q42651004 | Dual role of wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila |
Q34478110 | Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls |
Q41820010 | Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea |
Q57027256 | Dynamics of WNT signaling components in the human ovary from development to adulthood |
Q40303500 | Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling |
Q37274623 | Dysregulated molecular networks in head and neck carcinogenesis |
Q54334679 | Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1. |
Q33968068 | E-cadherin acts as a regulator of transcripts associated with a wide range of cellular processes in mouse embryonic stem cells |
Q40337889 | E-cadherin modulates Wnt-dependent transcription in colorectal cancer cells but does not alter Wnt-independent gene expression in fibroblasts |
Q39588984 | EBV-encoded LMP1 increases nuclear β-catenin accumulation and its transcriptional activity in nasopharyngeal carcinoma |
Q39698204 | EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis |
Q50992137 | ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation. |
Q37520284 | EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling |
Q98224541 | Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis |
Q52011383 | Ectopic sebaceous gland: a developmental anomaly. |
Q46524597 | Effect of Dietary-Resistant Starch on Inhibition of Colonic Preneoplasia and Wnt Signaling in Azoxymethane-Induced Rodent Models |
Q61443707 | Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes |
Q27309004 | Effect of doxorubicin/pluronic SP1049C on tumorigenicity, aggressiveness, DNA methylation and stem cell markers in murine leukemia |
Q35815397 | Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis |
Q52885276 | Effects of Dietary Resistant Starch on the Wnt Signaling Pathway and Preneoplastic Cells in the Colons of Azoxymethane-Treated Rats. |
Q50518034 | Effects of Wnt/β-catenin signalling on proliferation and differentiation of apical papilla stem cells. |
Q45853845 | Effects of a glycogen synthase kinase-3β inhibitor (LiCl) on c-myc protein in intervertebral disc cells |
Q35676086 | Effects of age and gender on WNT gene expression in human bone marrow stromal cells |
Q47744057 | Effects of genetic variants of the bovine WNT8A gene on nine important growth traits in beef cattle |
Q36474269 | Effects of growth factors and cytokines on osteoblast differentiation. |
Q37607632 | Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals |
Q35041516 | Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling. |
Q36485786 | Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1 |
Q35948915 | Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs |
Q28272256 | Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms |
Q38013550 | Embryonic stem cell markers. |
Q48189669 | Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer |
Q99406913 | Emerging Roles of Wnt Ligands in Human Colorectal Cancer |
Q36374633 | Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy |
Q33351225 | En1 and Wnt signaling in midbrain dopaminergic neuronal development |
Q36956908 | Endocytosis: a positive or a negative influence on Wnt signalling? |
Q39026766 | Endometrial Carcinoma: Specific Targeted Pathways. |
Q33788010 | Enhanced cancer stem cell properties of a mitotically quiescent subpopulation of p75NTR-positive cells in esophageal squamous cell carcinoma |
Q39231721 | Enrichment of Oct3/4-positive cells from a human bronchial epithelial cell line |
Q52313815 | Enteric Nervous System Regulation of Intestinal Stem Cell Differentiation and Epithelial Monolayer Function. |
Q34551512 | Enteric bacteria and cancer stem cells |
Q38014664 | EpCAM and its potential role in tumor-initiating cells |
Q35086401 | EpCAM and the biology of hepatic stem/progenitor cells |
Q35745241 | EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy |
Q30493364 | EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features |
Q40095580 | Epidermal growth factor inhibits glycogen synthase kinase-3 (GSK-3) and beta-catenin transcription in cultured ARPE-19 cells |
Q45388856 | Epidermal homeostasis and radiation responses in a multiscale tissue modeling framework |
Q24654755 | Epidermal homeostasis: a balancing act of stem cells in the skin |
Q38111202 | Epidermal stem cells in orthopaedic regenerative medicine |
Q36528809 | Epidermal stem cells of the skin |
Q35853581 | Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. |
Q37132659 | Epigenetic gene silencing in the Wnt pathway in breast cancer |
Q40200349 | Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia |
Q37858414 | Epigenetic regulation of aging stem cells |
Q37626242 | Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages |
Q34505232 | Epigenetics of prostate cancer: beyond DNA methylation |
Q35960157 | Epithelial cell adhesion molecule in human hepatocellular carcinoma cell lines: a target of chemoresistence |
Q33726440 | Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells |
Q37213607 | Epithelial morphogenesis and intestinal cancer: new insights in signaling mechanisms |
Q37425030 | Epithelial polarity: interactions between junctions and apical-basal machinery |
Q33916933 | Epithelial repair mechanisms in the lung |
Q36690919 | Epithelial stem cells: turning over new leaves |
Q57283456 | Epithelial-mesenchymal transition and cancer stem cells: at the crossroads of differentiation and dedifferentiation |
Q35884866 | Epithelial-mesenchymal transition in oral squamous cell carcinoma |
Q42555042 | Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon |
Q35006301 | Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal development |
Q34006736 | Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. |
Q36382713 | Establishment and functioning of intrathymic microenvironments. |
Q34335928 | Estrogen leads to reversible hair cycle retardation through inducing premature catagen and maintaining telogen |
Q33358936 | Estrogens and stem cells in thyroid cancer |
Q37395071 | Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study |
Q35082943 | Evidence for involvement of Wnt signalling in body polarities, cell proliferation, and the neuro-sensory system in an adult ctenophore |
Q33829820 | Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy |
Q34690600 | Evidence for tankyrases as antineoplastic targets in lung cancer. |
Q34387784 | Evidence for the importance of personalized molecular profiling in pancreatic cancer |
Q53631163 | Evidence that the canonical Wnt signalling pathway regulates deer antler regeneration. |
Q36209797 | Exendin-4 Inhibits Hepatic Lipogenesis by Increasing β-Catenin Signaling |
Q36000159 | Exogenous high-mobility group box 1 protein injection improves cardiac function after myocardial infarction: involvement of Wnt signaling activation |
Q51422684 | Exosomes Derived From Hypoxic Colorectal Cancer Cells Promote Angiogenesis Through Wnt4-Induced β-Catenin Signaling in Endothelial Cells. |
Q90751055 | Exosomes Derived from Hypoxic Colorectal Cancer Cells Transfer Wnt4 to Normoxic Cells to Elicit a Prometastatic Phenotype |
Q46359599 | Expression Levels and Localizations of DVL3 and sFRP3 in Glioblastoma |
Q28588826 | Expression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strain |
Q43298907 | Expression of Axin2 indicates a role for canonical Wnt signaling in development of the crown and root during pre- and postnatal tooth development |
Q34126349 | Expression of GPR177 (Wntless/Evi/Sprinter), a highly conserved Wnt-transport protein, in rat tissues, zebrafish embryos, and cultured human cells |
Q39692933 | Expression of Oct4 in HCC and modulation to wnt/β-catenin and TGF-β signal pathways |
Q35101935 | Expression of Reg family proteins in embryonic stem cells and its modulation by Wnt/beta-catenin signaling. |
Q44603877 | Expression of SRY-related HMG Box Transcription Factors (Sox) 2 and 9 in Craniopharyngioma Subtypes and Surrounding Brain Tissue |
Q90221130 | Expression of WNT1 in ameloblastoma and its significance |
Q50656448 | Expression of Wnt5a during development of anorectal malformations in a rat model of prenatal exposure to di(n-butyl) phthalate. |
Q43108806 | Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream |
Q44131003 | Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma. |
Q37536514 | Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck |
Q41931949 | Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1. |
Q36817102 | Expression patterns of Wnt signaling component, secreted frizzled‑related protein 3 in astrocytoma and glioblastoma. |
Q39587433 | Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates. |
Q24311824 | Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells |
Q33526036 | Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. |
Q28577689 | Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors |
Q33282863 | Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells |
Q58576736 | FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer |
Q89909161 | FGF9 promotes cisplatin resistance in colorectal cancer via regulation of Wnt/β-catenin signaling pathway |
Q92243283 | FK506 prevented bone loss in streptozotocin-induced diabetic rats via enhancing osteogenesis and inhibiting adipogenesis |
Q90576943 | FRAT1 Enhances the Proliferation and Tumorigenesis of CD133+Nestin+ Glioma Stem Cells In Vitro and In Vivo |
Q42436467 | FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in esophageal squamous cell carcinoma |
Q34007808 | FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway. |
Q39550398 | FZD7 has a critical role in cell proliferation in triple negative breast cancer |
Q27022335 | Factors and networks that underpin early hematopoiesis |
Q39575199 | Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation |
Q36216463 | Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation |
Q33530092 | Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden. |
Q38193721 | Fat and bone interactions |
Q37097913 | Feedback Regulation in a Cancer Stem Cell Model can Cause an Allee Effect. |
Q41124448 | Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway |
Q28484908 | Fibroblast growth factor receptor-mediated activation of AKT-β-catenin-CBP pathway regulates survival and proliferation of murine hepatoblasts and hepatic tumor initiating stem cells |
Q26744082 | Fibroepithelioma of Pinkus Revisited |
Q36348751 | Filtering transcriptional noise during development: concepts and mechanisms |
Q54484446 | Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells. |
Q48607312 | FoxM1 is vital in the Wnt/β-catenin signaling pathogenesis of gliomas. |
Q36059801 | Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors |
Q24337018 | Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability |
Q41817349 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors |
Q39001461 | Frequent hypermethylation of WNT pathway genes in laryngeal squamous cell carcinomas |
Q40081347 | Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas |
Q37297579 | Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer |
Q35086896 | Friend or foe: Endoplasmic reticulum protein 29 (ERp29) in epithelial cancer |
Q37649858 | Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells. |
Q41256855 | Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas. |
Q36545508 | Frizzled-7 promoter is highly active in tumors and promoter-driven Shiga-like toxin I inhibits hepatocellular carcinoma growth |
Q34788226 | Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer. |
Q48093281 | Frizzled7 Antibody-Functionalized Nanoshells Enable Multivalent Binding for Wnt Signaling Inhibition in Triple Negative Breast Cancer Cells. |
Q26849278 | Frizzled7 as an emerging target for cancer therapy |
Q38234418 | From experimental design to functional gene networks: DNA microarray contribution to skin ageing research |
Q38213433 | From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells. |
Q34977317 | From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging. |
Q36964320 | Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer |
Q43006045 | Function following form: functional differentiation of mammary epithelial cells requires laminin-induced polarization of PI3-kinase |
Q37595930 | Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer |
Q37372272 | Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin |
Q24320123 | Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells |
Q64939214 | Functional link between plasma membrane spatiotemporal dynamics, cancer biology, and dietary membrane-altering agents. |
Q28508864 | Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice |
Q37772128 | G-protein coupled receptors in stem cell self-renewal and differentiation. |
Q37200841 | G-protein-coupled receptors and melanoma |
Q35920539 | GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment |
Q37601318 | GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome? |
Q48299832 | GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen |
Q46228676 | GLI1, CTNNB1 and NOTCH1 protein expression in a thymic epithelial malignancy tissue microarray |
Q42453322 | GSK3beta affects apical-basal polarity and cell-cell adhesion by regulating aPKC levels |
Q37596883 | GSK3β activity is essential for senescence-associated heterochromatin foci (SAHF) formation induced by HMGA2 in WI38 cells |
Q36561625 | GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma |
Q35741579 | Galectin-3 augments tumor initiating property and tumorigenicity of lung cancer through interaction with β-catenin |
Q39252635 | Galectin-3 gene silencing inhibits migration and invasion of human tongue cancer cells in vitro via downregulating β-catenin |
Q38714564 | Gankyrin regulates cell signaling network |
Q47661011 | Gankyrin: a novel promising therapeutic target for hepatocellular carcinoma |
Q39292672 | Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer |
Q41894790 | Gene expression of growth signaling pathways is up-regulated in CD133-positive medulloblastoma cells |
Q54416904 | Gene expression patterns in the bone tissue of women with fibrous dysplasia |
Q84874923 | Gene expression profiling in mouse liver infected with Clonorchis sinensis metacercariae |
Q28285016 | Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals |
Q21135589 | Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway |
Q36656474 | Genetic Variants in the Wnt Signaling Pathway Are Not Associated with Survival Outcome of Non-Small Cell Lung Cancer in a Korean Population |
Q54458047 | Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report. |
Q35069181 | Genetic interaction analysis of TCF7L2 for biochemical recurrence after radical prostatectomy in localized prostate cancer. |
Q37350419 | Genetic models of cancer in zebrafish |
Q37696169 | Genetic polymorphisms of Wnt/β-catenin pathway genes are associated with the efficacy and toxicities of radiotherapy in patients with nasopharyngeal carcinoma |
Q33705233 | Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients |
Q39286333 | Genetics of Adrenocortical Development and Tumors |
Q37377851 | Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways |
Q33591835 | Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method |
Q36259297 | Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs |
Q39606660 | Genome-wide screen reveals WNT11, a non-canonical WNT gene, as a direct target of ETS transcription factor ERG. |
Q35225219 | Genome-wide sequence and functional analysis of early replicating DNA in normal human fibroblasts |
Q44255021 | Genomic compartmentalization of gene families encoding core components of metazoan signaling systems |
Q68691877 | Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis. |
Q37699112 | Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs. |
Q37127231 | Getting to the stem of chronic myeloid leukaemia |
Q38118310 | Ghost cells: A journey in the dark…. |
Q38043203 | Ghrelin O-acyltransferase assays and inhibition |
Q91639231 | Ginsenoside Rh2 activates α-catenin phosphorylation to inhibit lung cancer cell proliferation and invasion |
Q55358019 | Glioblastoma-targeted CD4+ CAR T cells mediate superior antitumor activity. |
Q37752381 | Glioma stem cell signaling: therapeutic opportunities and challenges |
Q61451737 | Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods |
Q39395261 | Global methylation profiling to identify epigenetic signature of gallbladder cancer and gallstone disease. |
Q34050208 | Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor |
Q24307581 | Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation |
Q41481540 | Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling |
Q33710200 | Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death |
Q38945181 | Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth. |
Q43105986 | Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging |
Q37698255 | Gradients in planarian regeneration and homeostasis |
Q28478455 | Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells |
Q41432008 | Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming |
Q42440768 | Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation |
Q64260986 | HDAC I inhibitor regulates RUNX2 transactivation through canonical and non-canonical Wnt signaling in aortic valvular interstitial cells |
Q33976964 | HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound. |
Q24337920 | HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies |
Q35919080 | HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis |
Q39018737 | HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice |
Q37362117 | HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer |
Q64912081 | HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations. |
Q39514539 | HSulf-1 inhibits cell proliferation and invasion in human gastric cancer |
Q99607499 | Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling |
Q54154094 | Healing efficacy of fracture-targeted GSK3β inhibitor-loaded micelles for improved fracture repair. |
Q35070272 | Heat shock proteins in breast cancer progression--a suitable case for treatment? |
Q36596124 | HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction. |
Q57615464 | Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation |
Q41814485 | Hematopoietic stem cell development requires transient Wnt/β-catenin activity |
Q37708991 | Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase |
Q50859715 | Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells. |
Q38788971 | Hepatic cancer stem cell marker granulin-epithelin precursor and β-catenin expression associate with recurrence in hepatocellular carcinoma |
Q60920093 | Hepatitis C virus core protein modulates several signaling pathways involved in hepatocellular carcinoma |
Q50490409 | Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon. |
Q36244287 | High Dickkopf-1 expression is associated with poor prognosis in patients with advanced urothelial carcinoma. |
Q37225362 | High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid |
Q41876961 | High Levels of Canonical Wnt Signaling Lead to Loss of Stemness and Increased Differentiation in Hematopoietic Stem Cells |
Q45770808 | High levels of β-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway |
Q38608910 | High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells |
Q35049311 | High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. |
Q41696798 | High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars. |
Q37457650 | Homeobox protein VentX induces p53-independent apoptosis in cancer cells |
Q37014671 | Host-microbe interaction: mechanisms of defensin deficiency in Crohn's disease. |
Q24305517 | Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements |
Q35147451 | Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells |
Q40299676 | Human sebaceous tumors harbor inactivating mutations in LEF1. |
Q60953217 | Hypermethylated and its clinical significance in colorectal cancer |
Q58583093 | Hypermethylation of Secreted Frizzled Related Protein 1 gene promoter in different astrocytoma grades |
Q44041187 | Hypervascular hepatocellular carcinomas showing hyperintensity on hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance imaging: a possible subtype with mature hepatocyte nature. |
Q38609714 | Hypoxia stimulates neural stem cell proliferation by increasing HIF‑1α expression and activating Wnt/β-catenin signaling |
Q39564222 | Hypoxia-induced β-catenin downregulation involves p53-dependent activation of Siah-1. |
Q37629893 | Hypoxia-inducible factors in stem cells and cancer |
Q33670820 | Hypoxic tumor microenvironment and cancer cell differentiation |
Q38659248 | ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection |
Q36916291 | IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer |
Q39030617 | ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw. |
Q35973324 | Id2 deletion attenuates Apc-deficient ileal tumor formation |
Q44756074 | Identification and validation that up-expression of HOXA13 is a novel independent prognostic marker of a worse outcome in gastric cancer based on immunohistochemistry |
Q28548040 | Identification of New Candidate Genes and Chemicals Related to Esophageal Cancer Using a Hybrid Interaction Network of Chemicals and Proteins |
Q39637431 | Identification of carbonic anhydrase 9 as a contributor to pingyangmycin-induced drug resistance in human tongue cancer cells |
Q51608321 | Identification of carcinogenic potential-associated molecular mechanisms in CD133(+) A549 cells based on microRNA profiles. |
Q30481751 | Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS |
Q33735853 | Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo |
Q34977426 | Identification of novel mutations by exome sequencing in African American colorectal cancer patients |
Q33412050 | Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening |
Q55530715 | Identification of proteins with potential osteogenic activity present in the water-soluble matrix proteins from Crassostrea gigas nacre using a proteomic approach. |
Q28131701 | Identification of stem cells in small intestine and colon by marker gene Lgr5 |
Q34168146 | Identification of transcription factors regulating CTNNAL1 expression in human bronchial epithelial cells |
Q36173081 | Identifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach |
Q30481466 | Imaging hematopoietic precursor division in real time |
Q38225580 | Imaging, genetic testing, and biomarker assessment of follicular cell-derived thyroid cancer |
Q91897107 | Immunoexpression of LGR4 and Β-Catenin in Gastric Cancer and Normal Gastric Mucosa |
Q90004966 | Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend |
Q92768544 | Immunometabolism: A new target for improving cancer immunotherapy |
Q36799983 | Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics |
Q93080888 | Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors |
Q35773743 | Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology |
Q34062409 | Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells |
Q30392749 | In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1 |
Q37305066 | In search of adrenocortical stem and progenitor cells |
Q28076101 | In vitro models of cancer stem cells and clinical applications |
Q36934236 | In vitro organoid culture of primary mouse colon tumors |
Q36837034 | In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model |
Q49095061 | In vivo tracing of canonical Wnt signaling in Xenopus tadpoles by means of an inducible transgenic reporter tool. |
Q45268115 | Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway |
Q37260274 | Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients |
Q35105262 | Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans |
Q47743734 | Increased expression of TBX2 is a novel independent prognostic biomarker of a worse outcome in colorectal cancer patients after curative surgery and a potential therapeutic target |
Q33792932 | Increased expression of colonic Wnt9A through Sp1-mediated transcriptional effects involving arylsulfatase B, chondroitin 4-sulfate, and galectin-3 |
Q34802543 | Increased levels of β-catenin, LEF-1, and HPA-1 correlate with poor prognosis for acral melanoma with negative BRAF and NRAS mutation in BRAF exons 11 and 15 and NRAS exons 1 and 2. |
Q36139562 | Increased nuclear β-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia |
Q48895485 | Increased β-catenin/Tcf signaling in pilocytic astrocytomas: a comparative study to distinguish pilocytic astrocytomas from low-grade diffuse astrocytomas. |
Q37407662 | Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis. |
Q34326719 | Indirect effects of Wnt3a/β-catenin signalling support mouse spermatogonial stem cells in vitro |
Q53077914 | Indole-3-Carbinol Promotes Goblet-Cell Differentiation Regulating Wnt and Notch Signaling Pathways AhR-Dependently. |
Q50802085 | Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice. |
Q39532407 | Induction of Wnt/β-catenin signaling in mouse mesenchymal stem cells is associated with activation of the p130 and E2f4 and formation of the p130/Gsk3β/β-catenin complex |
Q35628160 | Induction of cancer cell death by isoflavone: the role of multiple signaling pathways |
Q35082180 | Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis |
Q64110671 | Infection in Chronic Inflammation and Gastrointestinal Cancer |
Q38246263 | Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage |
Q42469909 | Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells |
Q57091284 | Inhibition of GSK3 and MEK induced cancer stem cell generation via the Wnt and MEK signaling pathways |
Q35995911 | Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D. |
Q37024249 | Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma |
Q35538822 | Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells |
Q34429613 | Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells |
Q37058912 | Inhibition of Wnt Signaling by Silymarin in Human Colorectal Cancer Cells |
Q43042100 | Inhibition of Wnt signaling and cancer stem cells |
Q35090349 | Inhibition of adipocytogenesis by canonical WNT signaling in human mesenchymal stem cells |
Q33560729 | Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth |
Q50157930 | Inhibition of miR-155, a therapeutic target for breast cancer, prevented in cancer stem cell formation. |
Q48017617 | Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy. |
Q99711034 | Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer |
Q34481563 | Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling |
Q44036647 | Inhibitory effect and mechanism of mesenchymal stem cells on liver cancer cells |
Q50949314 | Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. |
Q37786633 | Innate antimicrobial immunity in inflammatory bowel diseases |
Q42755826 | Inorganic polyphosphate promotes cyclin D1 synthesis through activation of mTOR/Wnt/β-catenin signaling in endothelial cells |
Q33735255 | Input of microenvironmental regulation on colorectal cancer: role of the CCN family |
Q35229856 | Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation |
Q36732647 | Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation. |
Q47343843 | Integrating expression-related SNPs into genome-wide gene- and pathway-based analyses identified novel lung cancer susceptibility genes. |
Q35126460 | Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer |
Q28084948 | Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma |
Q41458214 | Integrative analysis of cancer-related signaling pathways |
Q99207517 | Integrin-alpha-6+ Candidate stem cells are responsible for whole body regeneration in the invertebrate chordate Botrylloides diegensis |
Q28283184 | Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia |
Q24302002 | Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence |
Q34239769 | Interactions between cancer stem cells and their niche govern metastatic colonization |
Q33673605 | Intercellular transfer of proteins as identified by stable isotope labeling of amino acids in cell culture |
Q30500268 | Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells |
Q30434589 | Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells |
Q62556688 | Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging |
Q37083757 | Intestinal iron homeostasis and colon tumorigenesis |
Q35085948 | Intestinal stem cells and stem cell-based therapy for intestinal diseases |
Q34943574 | Intranodal palisaded myofibroblastoma: another mesenchymal neoplasm with CTNNB1 (β-catenin gene) mutations: clinicopathologic, immunohistochemical, and molecular genetic study of 18 cases |
Q34796316 | Intratracheal instillation of high dose adenoviral vectors is sufficient to induce lung injury and fibrosis in mice |
Q52653031 | Investigating a multigene prognostic assay based on significant pathways for Luminal A breast cancer through gene expression profile analysis. |
Q98289965 | Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway |
Q42735854 | Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia? |
Q34625269 | Isolation and characterization of a population of stem-like progenitor cells from an atypical meningioma. |
Q39055537 | Isolation, identification, and characterization of cancer stem cells: A review |
Q26822956 | Keeping Wnt signalosome in check by vesicular traffic |
Q37426789 | Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis |
Q47927511 | Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells |
Q24299779 | Knocking down Wnt9a mRNA levels increases cellular proliferation |
Q36579803 | Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival |
Q35269425 | Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine |
Q34375332 | LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer |
Q24329083 | LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element |
Q35001290 | LEF1 identifies androgen-independent epithelium in the developing prostate |
Q24313620 | LEF1 in androgen-independent prostate cancer: regulation of androgen receptor expression, prostate cancer growth, and invasion |
Q24606839 | LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling |
Q33740256 | LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy |
Q38878616 | LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells |
Q37249025 | Lack of Muc1-regulated beta-catenin stability results in aberrant expansion of CD11b+Gr1+ myeloid-derived suppressor cells from the bone marrow |
Q37304378 | Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer |
Q34751569 | Large scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells |
Q30499308 | Lentivirus-mediated Wnt11 gene transfer enhances Cardiomyogenic differentiation of skeletal muscle-derived stem cells |
Q30514843 | Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling |
Q37904866 | Lessons from common markers of tumor-initiating cells in solid cancers |
Q38118817 | Leukemia stem cells: Old concepts and new perspectives |
Q36030989 | Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future Directions |
Q34677521 | LgR5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett's esophagus? |
Q92260940 | Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy |
Q33767534 | Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis |
Q53447869 | Lgr5 marks cycling, yet long-lived, hair follicle stem cells. |
Q93004983 | Lgr6: From Stemness to Cancer Progression |
Q85036285 | Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis |
Q36496001 | Limbal stem cells, a review of their identification and culture for clinical use. |
Q46488088 | Lineage-specific evolution of cnidarian Wnt ligands. |
Q24301672 | Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom) |
Q34143422 | Linking cell signaling and the epigenetic machinery |
Q24541453 | Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin |
Q38640136 | Lipoprotein Receptor-related Protein 6 Signaling is Necessary for Vasculogenic Differentiation of Human Dental Pulp Stem Cells |
Q33359570 | Liposomal packaging generates Wnt protein with in vivo biological activity |
Q58776006 | Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway |
Q33523529 | Lithium chloride regulates the proliferation of stem-like cells in retinoblastoma cell lines: a potential role for the canonical Wnt signaling pathway. |
Q42795961 | Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases |
Q37015746 | Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin |
Q91822543 | Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of β-catenin/TCF/LEF signalling |
Q38931957 | Liver metastatic disease: new concepts and biomarker panels to improve individual outcomes |
Q37358938 | Liver stem cells and hepatocellular carcinoma |
Q46224632 | Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice |
Q79671125 | Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy |
Q34577033 | Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes |
Q43271997 | Long-term exposure to various types of dietary fat modulates acrylamide-induced preneoplastic lesions of colon mucosa through Wnt/beta-catenin signaling in rats |
Q28579732 | Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats |
Q83396650 | Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis |
Q43099080 | Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis. |
Q37208778 | Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype |
Q35872096 | Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis |
Q35042805 | Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice |
Q36488720 | Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo |
Q34408171 | Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors |
Q39859295 | Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy. |
Q40521041 | Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. |
Q34328494 | Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling |
Q37629583 | Lung cancer stem cells: Molecular features and therapeutic targets |
Q37718455 | Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia |
Q91272463 | Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway |
Q58700996 | Lysophosphatidic acid enhances breast cancer cells-mediated osteoclastogenesis |
Q33786774 | Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling |
Q24616764 | Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression |
Q34277630 | MENA is a transcriptional target of the Wnt/beta-catenin pathway |
Q39279697 | MMP7 is a target of the tumour-associated antigen EpCAM. |
Q35879924 | MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells |
Q52727524 | MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state. |
Q84039307 | Macrophage migration inhibitory factor is a direct target of HBP1-mediated transcriptional repression that is overexpressed in prostate cancer |
Q36457006 | Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways |
Q37818162 | Malignant melanoma: from cell kinetics to micrometastases |
Q37130864 | Mammalian Nemo-like kinase enhances β-catenin-TCF transcription activity in human osteosarcoma and neuroblastoma cells. |
Q35050344 | Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis |
Q34574786 | Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells |
Q37427798 | Management of the human mucosal defensive barrier: evidence for glycan legislation |
Q37331003 | Mapping key features of transcriptional regulatory circuitry in embryonic stem cells. |
Q46307051 | Mapping normal and cancer cell signalling networks: towards single-cell proteomics |
Q51701356 | Mathematical modelling and experiments for the proliferation and differentiation of Drosophila intestinal stem cells I. |
Q92537708 | Matrix Gla Protein Promotes the Bone Formation by Up-Regulating Wnt/β-Catenin Signaling Pathway |
Q38412794 | Maturation of cortical bone suppresses periosteal osteoprogenitor proliferation in a paracrine manner |
Q64955692 | Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer. |
Q38088654 | Mechanisms of RAS/β-catenin interactions |
Q36467836 | Mechanisms of disease: from stem cells to colorectal cancer. |
Q30575713 | Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype |
Q52569557 | Mediator is a transducer of Wnt/beta-catenin signaling. |
Q51052629 | Melatonin Inhibits Neural Cell Apoptosis and Promotes Locomotor Recovery via Activation of the Wnt/β-Catenin Signaling Pathway After Spinal Cord Injury. |
Q38197694 | Melatonin regulates mesenchymal stem cell differentiation: a review. |
Q90588984 | Melatonin reverses nasopharyngeal carcinoma cisplatin chemoresistance by inhibiting the Wnt/β-catenin signaling pathway |
Q48761731 | Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos. |
Q38650682 | Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5 |
Q34480237 | Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells |
Q36296784 | Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling |
Q36414996 | Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization |
Q42271898 | Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH. |
Q34178502 | Methylated CpG site count of dapper homolog 1 (DACT1) promoter prediction the poor survival of gastric cancer |
Q39254311 | Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome |
Q35974424 | Methylation-mediated molecular dysregulation in clinical oral malignancy |
Q37548379 | Methylprednisolone promotes recovery of neurological function after spinal cord injury: association with Wnt/β-catenin signaling pathway activation. |
Q36014206 | Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression |
Q37190321 | MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer |
Q39393414 | MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling |
Q35119958 | MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation |
Q58698448 | MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loop |
Q92276968 | MiR-509-5p improves the proliferative and invasive abilities of papillary thyroid carcinoma cells by inhibiting SFRP1 |
Q35172664 | MicroRNA MiR-199a-5p regulates smooth muscle cell proliferation and morphology by targeting WNT2 signaling pathway |
Q26771792 | MicroRNA Regulation of Human Breast Cancer Stem Cells |
Q90312107 | MicroRNA in Pancreatic Cancer: From Biology to Therapeutic Potential |
Q38850617 | MicroRNA in pancreatic cancer |
Q38696912 | MicroRNA-139-5p inhibits bladder cancer proliferation and self-renewal by targeting the Bmi1 oncogene |
Q53504882 | MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7. |
Q38804358 | MicroRNA-340 inhibits the migration, invasion, and metastasis of breast cancer cells by targeting Wnt pathway. |
Q37317467 | MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway |
Q35476764 | Microarray analysis of human adipose-derived stem cells in three-dimensional collagen culture: osteogenesis inhibits bone morphogenic protein and Wnt signaling pathways, and cyclic tensile strain causes upregulation of proinflammatory cytokine regul |
Q38770592 | Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots. |
Q36761864 | Microbial dysbiosis and colon carcinogenesis: could colon cancer be considered a bacteria-related disease? |
Q37439314 | Microenvironmental independence associated with tumor progression |
Q37890251 | Microenvironmental regulation of stem cells in intestinal homeostasis and cancer |
Q24653781 | Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11 |
Q43065072 | Minimizing the risk of cancer: tissue architecture and cellular replication limits |
Q28730326 | Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice |
Q27021818 | Mitotic and mitogenic Wnt signalling |
Q36486600 | Mitotic spindle (DIS)orientation and DISease: cause or consequence? |
Q33924425 | Modeling cell-cell interactions in regulating multiple myeloma initiating cell fate. |
Q49805610 | Modeling the Role of Wnt Signaling in Human and Drosophila Stem Cells. |
Q34032714 | Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts |
Q48269479 | Models of human adamantinomatous craniopharyngioma tissue: Steps toward an effective adjuvant treatment. |
Q37609953 | Modular Cre/lox system and genetic therapeutics for colorectal cancer |
Q34405122 | Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity |
Q34432431 | Modulating the stem cell niche for tissue regeneration |
Q28079530 | Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer |
Q35345488 | Modulation of canonical Wnt signaling by the extracellular matrix component biglycan |
Q34707660 | Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila. |
Q39800983 | Modulation of the tumor suppressor protein alpha-catenin by ischemic microenvironment. |
Q37004224 | Molecular Genetics of Colorectal Cancer: An Overview |
Q41446090 | Molecular Mechanism of β-Catenin Signaling Pathway Inactivation in ETV1-Positive Prostate Cancers |
Q36501328 | Molecular basis for the tissue specificity of β-catenin oncogenesis. |
Q33756006 | Molecular biology of liver cancer stem cells |
Q36836733 | Molecular dissection of microsatellite instable colorectal cancer |
Q21284820 | Molecular functions of thyroid hormones and their clinical significance in liver-related diseases |
Q37962744 | Molecular mediators of mesenchymal stem cell biology |
Q37763635 | Molecular pathways to CML stem cells |
Q33422792 | Molecular profiling of conjunctival epithelial side-population stem cells: atypical cell surface markers and sources of a slow-cycling phenotype |
Q34770823 | Molecular profiling predicts the existence of two functionally distinct classes of ovarian cancer stroma |
Q37711271 | Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells |
Q37176648 | Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy |
Q33455595 | Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer |
Q28749074 | Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathways |
Q27311697 | Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells |
Q38616107 | Moonlighting proteins in cancer. |
Q24646903 | More than one way to skin . . |
Q36830707 | Morphogens, morphostats, microarchitecture and malignancy |
Q28475186 | Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. |
Q47622665 | Msi2 plays a carcinogenic role in esophageal squamous cell carcinoma via regulation of the Wnt/β-catenin and Hedgehog signaling pathways |
Q26752365 | Multiple myeloma cancer stem cells |
Q35666438 | Musashi-2 promotes hepatitis Bvirus related hepatocellular carcinoma progression via the Wnt/β-catenin pathway. |
Q34720637 | Mutated beta-catenin evades a microRNA-dependent regulatory loop |
Q36447416 | Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A. |
Q28281731 | Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours |
Q100958900 | Mutations and mechanisms of WNT pathway tumour suppressors in cancer |
Q38694695 | Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells. |
Q39170190 | Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells. |
Q38246241 | Myeloma bone disease: pathogenesis, current treatments and future targets |
Q50753352 | Myocardial structural protein expression in umbilical cord blood mesenchymal stem cells after myogenic induction. |
Q34659995 | N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment |
Q40009083 | NF-kappaB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells |
Q37149896 | NKX6.3 Is a Transcription Factor for Wnt/β-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression |
Q28477683 | Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin |
Q38270098 | Nanomedicine strategies for hematological malignancies: what is next? |
Q58708009 | Nanomedicines reveal how PBOV1 promotes hepatocellular carcinoma for effective gene therapy |
Q36217643 | Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin |
Q34999115 | Nanosecond pulsed electric field inhibits cancer growth followed by alteration in expressions of NF-κB and Wnt/β-catenin signaling molecules |
Q42632502 | Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers |
Q94481776 | Negative binomial additive model for RNA-Seq data analysis |
Q80033357 | Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling |
Q54265665 | Neuroblastoma |
Q35837998 | Neuroprotective effect of rapamycin on spinal cord injury via activation of the Wnt/β-catenin signaling pathway |
Q48588244 | New Advances and Challenges of Targeting Cancer Stem Cells. |
Q33639180 | New Therapeutics Targeting Colon Cancer Stem Cells |
Q37215989 | New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential. |
Q24680988 | New molecularly targeted therapies for lung cancer |
Q39018424 | New perspectives for prostate cancer treatment: in vitro inhibition of LNCaP and PC3 cell proliferation by amnion-derived mesenchymal stromal cells conditioned media |
Q36519041 | New therapies for hepatocellular carcinoma. |
Q64951391 | Next Viable Routes to Targeting Pancreatic Cancer Stemness: Learning from Clinical Setbacks. |
Q39587242 | Niche-less maintenance of HSCs by 2i |
Q33500353 | No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer |
Q37627063 | Nodal promotes the self-renewal of human colon cancer stem cells via an autocrine manner through Smad2/3 signaling pathway |
Q42378466 | Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage |
Q39454318 | Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage. |
Q38189361 | Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation |
Q39110080 | Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes |
Q41398559 | Non-thermal Plasma Causes p53-Dependent Apoptosis in Human Colon Carcinoma Cells. |
Q31090776 | Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer |
Q35821670 | Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche |
Q28585201 | Noncanonical Wnt signaling promotes apoptosis in thymocyte development |
Q38940107 | Noncanonical Wnt5a-Ca(2+) -NFAT signaling axis in pesticide induced bone marrow aplasia mouse model: A study to explore the novel mechanism of pesticide toxicity |
Q36474886 | Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia |
Q36480684 | Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses |
Q37237414 | Notch and wingless signaling cooperate in regulation of dendritic cell differentiation |
Q47220353 | Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression |
Q37169972 | Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition |
Q52670911 | Notch synergizes with axin to regulate the activity of armadillo in Drosophila. |
Q52574734 | Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. |
Q53317867 | Notch1 expression in colorectal carcinoma determines tumor differentiation status. |
Q51979665 | Novel Robinow syndrome causing mutations in the proximal region of the frizzled-like domain of ROR2 are retained in the endoplasmic reticulum. |
Q24676528 | Novel c-MYC target genes mediate differential effects on cell proliferation and migration |
Q38114502 | Novel drug discovery opportunities for colorectal cancer |
Q40176341 | Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway. |
Q37738484 | Novel insights into the development of T-cell acute lymphoblastic leukemia. |
Q35902006 | Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development |
Q33343446 | Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. |
Q37198168 | Novel strategies targeting cancer stem cells through phytochemicals and their analogs |
Q34289576 | Novel targets for prostate cancer chemoprevention |
Q34940971 | Novel therapeutic strategies for targeting liver cancer stem cells |
Q64964513 | Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs. |
Q46047714 | Nuclear expression and gain-of-function β-catenin mutation in glomangiopericytoma (sinonasal-type hemangiopericytoma): insight into pathogenesis and a diagnostic marker. |
Q87036473 | Nuclear expression of β-catenin predicts the efficacy of meloxicam treatment for patients with sporadic desmoid tumors |
Q35831988 | Nuclear lamins: key regulators of nuclear structure and activities |
Q24315870 | Nuclear signalling by tumour-associated antigen EpCAM |
Q35684848 | Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation |
Q39146122 | Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis. |
Q37279704 | Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology. |
Q27026694 | Nutritional regulation of stem and progenitor cells in Drosophila |
Q33913190 | O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. |
Q35129302 | O2 regulates stem cells through Wnt/β-catenin signalling. |
Q34211306 | Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling |
Q38705603 | Oct4 induces EMT through LEF1/β-catenin dependent WNT signaling pathway in hepatocellular carcinoma |
Q48273193 | Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells. |
Q34424883 | Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. |
Q35889072 | Oncogenesis and cancer stem cells: current opinions and future directions |
Q35066337 | Oncogenesis and induced pluripotency - commonalities of signalling pathways |
Q36043468 | Oncogenicity of the developmental transcription factor Sox9. |
Q28576842 | Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons |
Q81573645 | Opinion: the origin of the cancer stem cell: current controversies and new insights |
Q42092681 | Opposite spectrum of activity of canonical Wnt signaling in the osteogenic context of undifferentiated and differentiated mesenchymal cells: implications for tissue engineering |
Q47330933 | Oral Cancer Stem Cells Microenvironment. |
Q21090715 | Organized emergence of multiple-generations of teeth in snakes is dysregulated by activation of Wnt/beta-catenin signalling |
Q56556302 | Oridonin inhibits growth and induces apoptosis of human neurocytoma cells via the Wnt/β-catenin pathway |
Q37861635 | Origin and maintenance of the intestinal cancer stem cell |
Q36677501 | Original CIN: reviewing roles for APC in chromosome instability |
Q36803600 | Osteosarcoma development and stem cell differentiation |
Q37415611 | Ovarian cancer update: lessons from morphology, molecules, and mice |
Q45989150 | Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells. |
Q36413067 | Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer. |
Q37954295 | Overcoming multidrug resistance in human cancer cells by natural compounds |
Q90465703 | Overexpression of HDAC6 suppresses tumor cell proliferation and metastasis by inhibition of the canonical Wnt/β-catenin signaling pathway in hepatocellular carcinoma |
Q36334142 | Overexpression of HOXB7 is associated with a poor prognosis in patients with gastric cancer |
Q36986217 | Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway |
Q55690589 | Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus. |
Q33791918 | Overexpression of Wnt5a promotes angiogenesis in NSCLC. |
Q83729519 | Overexpression of nuclear NHERF1 in advanced colorectal cancer: association with hypoxic microenvironment and tumor invasive phenotype |
Q36733465 | Oxygen sensing and redox signaling: the role of thioredoxin in embryonic development and cardiac diseases |
Q42098686 | PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression |
Q44554105 | PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers. |
Q24654901 | PCAF acetylates {beta}-catenin and improves its stability |
Q35107382 | PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing |
Q64236663 | PIK3CD induces cell growth and invasion by activating AKT/GSK-3β/β-catenin signaling in colorectal cancer |
Q24615768 | PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas |
Q52352270 | PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells. |
Q38168831 | PP2A-Mediated Anticancer Therapy |
Q91560799 | Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis |
Q37952082 | Pancreatic cancer stem cell biology and its therapeutic implications |
Q26741215 | Pancreatic cancer stem cell markers and exosomes - the incentive push |
Q38516947 | Pancreatic cancer stem cells. |
Q38180221 | Pancreatic gene variants potentially associated with dipeptidyl peptidase-4 inhibitor treatment response in Type 2 diabetes |
Q51459248 | Paper-based microreactor array for rapid screening of cell signaling cascades. |
Q37240573 | Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth |
Q41088460 | Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation |
Q35157066 | Parameter-free methods distinguish Wnt pathway models and guide design of experiments |
Q37595673 | Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling |
Q38428260 | Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells |
Q36644898 | Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy |
Q64056913 | Penfluridol overcomes paclitaxel resistance in metastatic breast cancer |
Q52625208 | Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation. |
Q24650730 | Ph+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cells |
Q35619694 | Pharmacologic induction of CD8+ T cell memory: better living through chemistry |
Q34892759 | Pharmacophore modeling, 3D-QSAR and DFT studies of IWR small-molecule inhibitors of Wnt response |
Q38816754 | Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines |
Q34091635 | Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis |
Q36752069 | Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts |
Q98513563 | Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes |
Q38023557 | Physiological functions of GPx2 and its role in inflammation-triggered carcinogenesis |
Q35001181 | Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma |
Q97568858 | Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells |
Q37452373 | Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice. |
Q38293612 | Pivotal role of pervasive neoplastic and stromal cells reprogramming in circulating tumor cells dissemination and metastatic colonization. |
Q36924388 | Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling |
Q38988584 | Plumbagin and Its Role in Chronic Diseases |
Q42051646 | Plumbagin exhibits an anti-proliferative effect in human osteosarcoma cells by downregulating FHL2 and interfering with Wnt/β-catenin signalling |
Q37122739 | Pluripotency and nuclear reprogramming |
Q42259647 | Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity |
Q37629613 | Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer |
Q29619697 | Polycomb silencers control cell fate, development and cancer |
Q36342403 | Polymer-drug conjugates for intracellar molecule-targeted photoinduced inactivation of protein and growth inhibition of cancer cells |
Q37591364 | Ponatinib efficiently kills imatinib-resistant chronic eosinophilic leukemia cells harboring gatekeeper mutant T674I FIP1L1-PDGFRα: roles of Mcl-1 and β-catenin. |
Q36775710 | Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552 |
Q57291734 | Posters |
Q64118291 | Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling |
Q35540034 | Potential of Mesenchymal Stem Cell based application in Cancer |
Q42700663 | Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype |
Q39122669 | Prdm5 suppresses Apc(Min)-driven intestinal adenomas and regulates monoacylglycerol lipase expression. |
Q36989548 | Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. |
Q35702897 | Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome. |
Q36698501 | Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors |
Q55038918 | Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer. |
Q36482223 | Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation |
Q35261950 | Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway |
Q35130563 | Primary small cell carcinoma of the esophagus: clinicopathological study of 44 cases |
Q37469714 | Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells |
Q35324807 | Prognostic parameters for the primary care of melanoma patients: what is really risky in melanoma? |
Q39635505 | Prognostic value of Wnt inhibitory factor-1 expression in hepatocellular carcinoma that is independent of gene methylation. |
Q34976602 | Programming CD8+ T cells for effective immunotherapy. |
Q38078312 | Progress in the reprogramming of somatic cells |
Q35210449 | Prokineticin 1 induces Dickkopf 1 expression and regulates cell proliferation and decidualization in the human endometrium |
Q91291212 | Propofol suppresses proliferation and migration of papillary thyroid cancer cells by down-regulation of lncRNA ANRIL |
Q38020001 | Prorenin receptor regulates more than the renin-angiotensin system |
Q34885515 | Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization |
Q57138061 | Prostate cancer stem cells |
Q34000532 | Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK). |
Q24298111 | Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex |
Q38826163 | Protein-Specific Imaging of O-GlcNAcylation in Single Cells. |
Q33237312 | Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis. |
Q39491823 | Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations. |
Q26738712 | Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer |
Q28510950 | Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context |
Q33925855 | Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia |
Q37411863 | Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling |
Q28476367 | Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling |
Q33281138 | Qualitative networks: a symbolic approach to analyze biological signaling networks |
Q35815971 | Quantitative Differences in Nuclear β-catenin and TCF Pattern Embryonic Cells in C. elegans |
Q39836950 | Quantitative Phosphoproteomic Study Reveals that Protein Kinase A Regulates Neural Stem Cell Differentiation Through Phosphorylation of Catenin Beta-1 and Glycogen Synthase Kinase 3β. |
Q59793350 | Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device |
Q41886588 | Quercetin Confers Tumoricidal Activity Through Multipathway Mechanisms in A N-Methylnitrosourea Rat Model of Colon Cancer |
Q37799253 | Quiescent, slow-cycling stem cell populations in cancer: a review of the evidence and discussion of significance |
Q58572053 | R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells |
Q91993511 | RCC2 promotes breast cancer progression through regulation of Wnt signaling and inducing EMT |
Q33380402 | REST regulates distinct transcriptional networks in embryonic and neural stem cells |
Q49456346 | RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1. |
Q50054622 | RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance. |
Q34628925 | RHOA inactivation enhances Wnt signalling and promotes colorectal cancer. |
Q36637143 | RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer |
Q58695635 | Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness |
Q35791224 | Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. |
Q36629426 | Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells |
Q43788473 | Radiofrequency ablation for dysplasia in Barrett's esophagus restores β-catenin activation within esophageal progenitor cells. |
Q81113722 | Ratio of Wnt3a to BMP4 doses is critical to their synergistic effects on proliferation of differentiating mouse embryonic stem cells |
Q89026179 | Re-Evaluating E-Cadherin and β-Catenin: A Pan-Cancer Proteomic Approach with an Emphasis on Breast Cancer |
Q37271085 | Real-Time Analysis of Endogenous Wnt Signalling in 3D Mesenchymal Stromal Cells. |
Q26797285 | Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models |
Q35459525 | Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers |
Q37197074 | Recent advances in cardiovascular regenerative medicine: the induced pluripotent stem cell era. |
Q33730375 | Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies |
Q33514162 | Recent data in adrenocortical tumorigenesis |
Q37310063 | Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications |
Q34507622 | Receptor heterodimerization as a novel mechanism for the regulation of Wnt/β-catenin signaling |
Q92001056 | Receptor subtype discrimination using extensive shape complementary designed interfaces |
Q33618799 | Reciprocal control of lncRNA-BCAT1 and β-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer |
Q57279171 | Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4 |
Q34324645 | Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. |
Q33884823 | Red Deer Antler Extract Accelerates Hair Growth by Stimulating Expression of Insulin-like Growth Factor I in Full-thickness Wound Healing Rat Model. |
Q37699347 | Redox regulation of Wnt signalling via nucleoredoxin |
Q35550094 | Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell-like phenotype |
Q39134073 | Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules |
Q63407739 | Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor |
Q38852157 | Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins. |
Q64068191 | Regulation of Wnt Singaling Pathway by Poly (ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Lung Cancer in Mice Induced by Benzo(a)pyrene Inhalation Exposure |
Q34576629 | Regulation of bone mass by Wnt signaling |
Q37208020 | Regulation of dendritic cell differentiation in bone marrow during emergency myelopoiesis |
Q38225994 | Regulation of hematopoietic and leukemic stem cells by the immune system. |
Q38864687 | Regulation of metastasis of bladder cancer cells through the WNT signaling pathway |
Q21284160 | Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells |
Q35171019 | Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt. |
Q26853096 | Regulation of ovarian cancer stem cells or tumor-initiating cells |
Q37371602 | Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl |
Q36972353 | Regulation of protumorigenic pathways by insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis |
Q37707515 | Regulation of stem cell function by protein ubiquitylation |
Q36288064 | Regulation of the adrenocortical stem cell niche: implications for disease |
Q36229240 | Repression of BCL-6 is required for the formation of human memory B cells in vitro |
Q41502015 | Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene |
Q37343986 | Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells |
Q35412202 | Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR. |
Q36742802 | Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers |
Q30426494 | Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines |
Q34418424 | Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer |
Q42377913 | Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia. |
Q42781875 | Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine |
Q35837893 | Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway |
Q37360869 | Retinoid signaling in control of progenitor cell differentiation during mouse development |
Q36284219 | Retracted: Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation |
Q39125214 | Review on the role of the human Polyomavirus JC in the development of tumors. |
Q89658859 | Revisiting the Roles of Pro-Metastatic EpCAM in Cancer |
Q37471296 | Rho GTPases in hematopoietic stem cell functions |
Q33532622 | Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner |
Q37012033 | Road for understanding cancer stem cells: model cell lines |
Q57470592 | Role of AhR in Regulating Cancer Stem Cell-like Characteristics in Choriocarcinoma |
Q43122590 | Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail. |
Q34033323 | Role of Cripto-1 in stem cell maintenance and malignant progression |
Q35804641 | Role of GAC63 in transcriptional activation mediated by beta-catenin |
Q34055747 | Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme |
Q51903398 | Role of Lef1 in sustaining self-renewal in mouse embryonic stem cells. |
Q34697373 | Role of Notch and its oncogenic signaling crosstalk in breast cancer |
Q92702508 | Role of Secreted Frizzled-Related Protein 1 in Early Mammary Gland Tumorigenesis and Its Regulation in Breast Microenvironment |
Q39012183 | Role of Wnt5a in the Pathogenesis of Inflammatory Diseases. |
Q24320028 | Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: regulation of lymphoid enhancer-binding factor 1 |
Q34259112 | Role of liver stem cells in hepatocarcinogenesis |
Q28076798 | Role of nanotechnology and gene delivery systems in TRAIL-based therapies |
Q38014421 | Role of the wnt pathway in thyroid cancer |
Q37027389 | Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling. |
Q34566517 | Roles of Wnt/β-catenin signaling in retinal neuron-like differentiation of bone marrow mesenchymal stem cells from nonobese diabetic mice |
Q33695152 | Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment |
Q53348663 | Roots and stems: stem cells in cancer. |
Q33385660 | Runx expression is mitogenic and mutually linked to Wnt activity in blastula-stage sea urchin embryos |
Q89230444 | Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity |
Q34659163 | Rutin mediated targeting of signaling machinery in cancer cells. |
Q47747424 | SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis |
Q24685799 | SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice |
Q35939318 | SEL1L, an UPR response protein, a potential marker of colonic cell transformation |
Q35097426 | SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway |
Q28240835 | SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress |
Q92433227 | SOX12 promotes the growth of multiple myeloma cells by enhancing Wnt/β-catenin signaling |
Q42379103 | SOX15 regulates proliferation and migration of endometrial cancer cells |
Q37689061 | SOX17 is a tumor suppressor in endometrial cancer |
Q42969109 | SOX9 Is Highly Expressed in Nonampullary Duodenal Adenoma and Adenocarcinoma in Humans |
Q42404921 | SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma. |
Q53224289 | SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans. |
Q37041810 | STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation. |
Q36195433 | Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133(+) human colorectal cancer cells |
Q90190759 | Salinomycin-Loaded Iron Oxide Nanoparticles for Glioblastoma Therapy |
Q39432450 | Salinomycin: a new cancer drug candidate |
Q26853644 | Salinomycin: a novel anti-cancer agent with known anti-coccidial activities |
Q33693378 | Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway |
Q89681983 | Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway |
Q36295027 | Sca-1 knockout impairs myocardial and cardiac progenitor cell function |
Q47561285 | Scarless wound healing: Transitioning from fetal research to regenerative healing |
Q33703825 | Secreted frizzled-related protein 4: an angiogenesis inhibitor. |
Q42040756 | Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass. |
Q39098971 | Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen |
Q36040176 | Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage |
Q61809837 | Self-antigen MASH2 combined with the AS15 immunostimulant induces tumor protection in colorectal cancer mouse models |
Q33847891 | Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target |
Q35374106 | Serum vitamin D levels of patients with oral squamous cell carcinoma (OSCC) and expression of vitamin D receptor in oral precancerous lesions and OSCC. |
Q24632319 | Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members. |
Q26864979 | Sheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transition |
Q40262786 | Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties |
Q37159360 | Signal transduction and transcriptional regulation during mesenchymal cell differentiation. |
Q36081663 | Signaling circuitries controlling stem cell fate: to be or not to be. |
Q37535695 | Signaling involved in hair follicle morphogenesis and development |
Q34688315 | Signaling pathways in cancer and embryonic stem cells |
Q92015158 | Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β‑catenin signaling pathway |
Q36871666 | Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex |
Q35661951 | Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. |
Q38980557 | Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals |
Q34604921 | Similar regulatory logic in Ciona intestinalis for two Wnt pathway modulators, ROR and SFRP-1/5. |
Q37481066 | Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus. |
Q37384938 | Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β-catenin signaling pathway after spinal cord injury |
Q61961170 | Skeletal Stem Cell Niche of the Bone Marrow |
Q37354085 | Skeletal metastasis: treatments, mouse models, and the Wnt signaling |
Q37580273 | Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers |
Q45999803 | Small Molecules Inspired by the Natural Product Withanolides as Potent Inhibitors of Wnt Signaling. |
Q39376795 | Small molecule antibody targeting HLA class I inhibits myeloma cancer stem cells by repressing pluripotency-associated transcription factors |
Q41664279 | Small molecule induces Wnt asymmetry in cancer |
Q34817365 | Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic |
Q24305423 | Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo |
Q45071326 | Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer |
Q29616163 | Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer |
Q35076609 | Small molecules for cell reprogramming and heart repair: progress and perspective |
Q38867041 | Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia |
Q36897356 | Small-molecule modulators of Hh and Wnt signaling pathways |
Q37184855 | Sol narae (Sona) is a Drosophila ADAMTS involved in Wg signaling |
Q51897323 | Some dynamic aspects of hematopoietic stem cells. |
Q33947311 | Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium |
Q39385532 | Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression. |
Q55051527 | Sost Deficiency does not Alter Bone's Lacunar or Vascular Porosity in Mice. |
Q64087639 | Sost Haploinsufficiency Provokes Peracute Lethal Cardiac Tamponade without Rescuing the Osteopenia in a Mouse Model of Excess Glucocorticoids |
Q42476158 | Spatially defined Dsh–Lgl interaction contributes to directional tissue morphogenesis |
Q37034716 | Stabilization of beta-catenin induces pancreas tumor formation |
Q36994927 | Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. |
Q45349682 | Static magnetic fields promote osteoblastic/cementoblastic differentiation in osteoblasts, cementoblasts, and periodontal ligament cells. |
Q28076017 | Stem cell dynamics and pretumor progression in the intestinal tract |
Q36837256 | Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells. |
Q36547723 | Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors. |
Q38586627 | Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy |
Q38084129 | Stem cells and cancer stem-like cells in endocrine tissues |
Q35084713 | Stem cells and female reproduction |
Q38160452 | Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements. |
Q36943344 | Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective. |
Q37777341 | Stem cells in colon cancer. A new era in cancer theory begins |
Q36117797 | Stem cells in melanoma development |
Q37633655 | Stem cells in the pituitary gland: A burgeoning field |
Q37936212 | Stem cells, quiescence and rectal carcinoma: an unexplored relationship and potential therapeutic target. |
Q33572252 | Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment. |
Q27675072 | Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6 |
Q24618445 | Structural basis of Wnt recognition by Frizzled |
Q35166834 | Structural studies of human Naked2: a biologically active intrinsically unstructured protein |
Q39875693 | Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells |
Q41963881 | Structure-activity relationship studies of small-molecule inhibitors of Wnt response |
Q36381984 | Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled |
Q37694627 | Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing |
Q33974251 | Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice |
Q39277545 | Suppression of GSK3β by ERK mediates lipopolysaccharide induced cell migration in macrophage through β-catenin signaling |
Q54551098 | Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer. |
Q28298718 | Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1 |
Q37205875 | Suppression of colon carcinogenesis by targeting Notch signaling |
Q47272524 | Suppression of corneal neovascularization by curcumin via inhibition of Wnt/β-catenin pathway activation |
Q39998770 | Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model |
Q38936660 | Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro |
Q37186425 | Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis |
Q53303425 | Survivin expression in colorectal carcinomas: correlations with clinicopathological parameters and survival. |
Q35034585 | Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer? |
Q39009114 | Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/β-catenin pathways |
Q30352525 | Synthesis of sydnone substituted Biginelli derivatives as hyaluronidase inhibitors. |
Q34061158 | Synthetic, non-saccharide, glycosaminoglycan mimetics selectively target colon cancer stem cells. |
Q28085367 | Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma |
Q39733618 | TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling |
Q34125637 | TBX2 and TBX3: the special value for anticancer drug targets. |
Q34119730 | TCF-3, 4 protein expression correlates with beta-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers |
Q26742019 | TCF/LEF Transcription Factors: An Update from the Internet Resources |
Q90178576 | TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer |
Q38950688 | TCF7 is suppressed by the androgen receptor via microRNA-1-mediated downregulation and is involved in the development of resistance to androgen deprivation in prostate cancer |
Q37030861 | TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3 |
Q28589957 | TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver |
Q89737194 | TFRC promotes epithelial ovarian cancer cell proliferation and metastasis via up-regulation of AXIN2 expression |
Q34819515 | TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells |
Q48132057 | TGF-β1-induced CK17 enhances cancer stem cell-like properties rather than EMT in promoting cervical cancer metastasis via the ERK1/2-MZF1 signaling pathway |
Q37195207 | TGFbeta promotes Wnt expression during cataract development |
Q35941309 | TLR4 Activation Promotes Bone Marrow MSC Proliferation and Osteogenic Differentiation via Wnt3a and Wnt5a Signaling |
Q38739472 | TNF-alpha and Notch signaling regulates the expression of HOXB4 and GATA3 during early T lymphopoiesis |
Q91522152 | TNIK signaling imprints CD8+ T cell memory formation early after priming |
Q39434911 | TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy |
Q92617776 | TREX1 suppression imparts cancer-stem-cell-like characteristics to CD133- osteosarcoma cells through the activation of E2F4 signaling |
Q52725560 | TROY is a promising prognostic biomarker in patients with colorectal cancer. |
Q38767082 | Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway |
Q90887447 | Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts |
Q42081151 | Targeted Therapy of Breast Cancer - New Insights and Perspectives |
Q24632740 | Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling |
Q34101433 | Targeted therapies for adrenocortical carcinoma: IGF and beyond |
Q35802983 | Targeted therapy against cancer stem cells |
Q37619860 | Targeting BET bromodomain proteins in solid tumors |
Q64070902 | Targeting HOX/PBX dimer formation as a potential therapeutic option in esophageal squamous cell carcinoma |
Q37622949 | Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer |
Q37100742 | Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling |
Q49544368 | Targeting Stemness: Implications for Precision Medicine in Breast Cancer. |
Q26774623 | Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment |
Q37820099 | Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways |
Q26783590 | Targeting cancer stem cells by using the nanoparticles |
Q37975244 | Targeting embryonic signaling pathways in cancer therapy |
Q26766395 | Targeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia? |
Q26775961 | Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy |
Q36478661 | Targeting stem cells in brain tumors |
Q39400127 | Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics |
Q50696441 | Targeting the Wnt pathway in zebrafish as a screening method to identify novel therapeutic compounds. |
Q35778231 | Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma. |
Q34153051 | Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers |
Q84592877 | Tcf proteins are deeply rooted in skin |
Q28591794 | Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia |
Q28587342 | Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells |
Q38139289 | Telomerase and its extracurricular activities. |
Q24615809 | Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer |
Q24310084 | Telomerase modulates Wnt signalling by association with target gene chromatin |
Q89120729 | Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells |
Q36285737 | Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria |
Q37846533 | Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins |
Q38983964 | Temporal perturbation of the Wnt signaling pathway in the control of cell reprogramming is modulated by TCF1. |
Q90115372 | The (pro)renin receptor: a novel biomarker and potential therapeutic target for various cancers |
Q40309718 | The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes |
Q39071403 | The Cellular Origin and Evolution of Breast Cancer |
Q36514299 | The Current and Future Therapies for Human Osteosarcoma |
Q24310085 | The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin |
Q37134198 | The Emerging Picture of Human Breast Cancer as a Stem Cell-based Disease. |
Q64286848 | The FZD7-TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma |
Q37005651 | The FoxO transcription factors and metabolic regulation |
Q35849783 | The Functional SNPs in the 5' Regulatory Region of the Porcine PPARD Gene Have Significant Association with Fat Deposition Traits |
Q55483353 | The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer. |
Q77049440 | The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling |
Q33855576 | The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells |
Q21145899 | The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling |
Q35464851 | The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation |
Q39417818 | The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma |
Q90394601 | The Role of Polycomb Repressive Complex in Malignant Peripheral Nerve Sheath Tumor |
Q38202820 | The Role of Tricho-Rhino-Phalangeal Syndrome (TRPS) 1 in Apoptosis during Embryonic Development and Tumor Progression |
Q49804881 | The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor. |
Q49593660 | The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets. |
Q41510704 | The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. |
Q26749450 | The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells |
Q37543996 | The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells |
Q34577694 | The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells. |
Q28507014 | The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development |
Q50949116 | The Wnt inhibitor secreted Frizzled-Related Protein 1 (sFRP1) promotes human Th17 differentiation. |
Q35085317 | The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence |
Q39432100 | The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis |
Q34688333 | The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion. |
Q28589724 | The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis |
Q38698293 | The Wnt/β-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation |
Q34670501 | The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target. |
Q37928570 | The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer |
Q37215096 | The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer |
Q33316388 | The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens |
Q35849968 | The anti-obesity effects of a tuna peptide on 3T3-L1 adipocytes are mediated by the inhibition of the expression of lipogenic and adipogenic genes and by the activation of the Wnt/β-catenin signaling pathway |
Q28274002 | The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation |
Q33412512 | The atonal proneural transcription factor links differentiation and tumor formation in Drosophila |
Q34284208 | The balance between two isoforms of LEF-1 regulates colon carcinoma growth |
Q42006583 | The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner |
Q33987011 | The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development |
Q38006769 | The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells |
Q37351482 | The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation. |
Q39924925 | The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression |
Q37954461 | The biology of head and neck cancer stem cells |
Q37013896 | The c-myc promoter: still MysterY and challenge |
Q36854372 | The cancer stem cell paradigm: a new understanding of tumor development and treatment |
Q36293300 | The canonical Wg signaling modulates Bsk-mediated cell death in Drosophila |
Q36916471 | The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis |
Q36535617 | The canonical Wnt signalling pathway and its APC partner in colon cancer development |
Q38175297 | The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells. |
Q54354272 | The changes of stemness biomarkers expression in human adipose-derived stem cells during long-term manipulation. |
Q38197098 | The colon cancer stem cell microenvironment holds keys to future cancer therapy |
Q36977621 | The complex pathways of Wnt 5a in cancer progression |
Q38059785 | The complex world of WNT receptor signalling |
Q37977006 | The contribution of bone to whole-organism physiology |
Q36672152 | The contribution of epidermal stem cells to skin cancer |
Q39090367 | The cross-regulation between SOX15 and Wnt signaling pathway |
Q35566484 | The crossroads between cancer stem cells and aging. |
Q24623318 | The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice |
Q35394164 | The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes |
Q36842360 | The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia. |
Q37551261 | The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells |
Q34310378 | The epigenetics of epithelial-mesenchymal plasticity in cancer |
Q36515479 | The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies |
Q37285682 | The first propeller domain of LRP6 regulates sensitivity to DKK1. |
Q37035383 | The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology |
Q38608775 | The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma |
Q38569328 | The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell |
Q38045265 | The hitchhikers guide to cancer stem cell theory: markers, pathways and therapy. |
Q36797661 | The implications of small stem cell niche sizes and the distribution of fitness effects of new mutations in aging and tumorigenesis |
Q39372971 | The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). |
Q26751224 | The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets |
Q36545318 | The metastasis suppressor, NDRG1, inhibits "stemness" of colorectal cancer via down-regulation of nuclear β-catenin and CD44. |
Q38644651 | The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells |
Q37189432 | The molecular genetics of medulloblastoma: an assessment of new therapeutic targets |
Q36231787 | The molecular repertoire of the 'almighty' stem cell |
Q40560744 | The next new target in leukemia: The embryonic stem cell gene SALL4. |
Q26849444 | The niche under siege: novel targets for metastasis therapy |
Q59098615 | The not-so-odd couple |
Q37317534 | The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance |
Q34489510 | The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas |
Q35348787 | The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling |
Q59548470 | The pathogenic role of Notch activation in podocytes |
Q36790737 | The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues. |
Q38202202 | The potential of targeting Wnt/β-catenin in colon cancer |
Q24319976 | The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling |
Q38304775 | The recovery process of mice tracheal epithelium injured by 5-FU and its microarray analysis |
Q33630327 | The repressive effect of miR-148a on Wnt/β-catenin signaling involved in Glabridin-induced anti-angiogenesis in human breast cancer cells |
Q39028181 | The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer |
Q37365676 | The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells |
Q37610703 | The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells. |
Q44669927 | The role of Pygopus 2 in rat glioma cell growth |
Q28468370 | The role of T‑box genes in the tumorigenesis and progression of cancer (Review) |
Q38216639 | The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance |
Q37029666 | The role of matrix metalloproteinases in stromal/epithelial interactions in the gut. |
Q24613730 | The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer |
Q37858470 | The role of p63 in cancer, stem cells and cancer stem cells. |
Q36292780 | The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt |
Q37139152 | The role of thyroid hormone signaling in the prevention of digestive system cancers |
Q51945868 | The roles of Wnt antagonists Dkk1 and sFRP4 during adipogenesis of human adipose tissue-derived mesenchymal stem cells. |
Q34018084 | The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity |
Q21560986 | The spatial distribution of LGR5+ cells correlates with gastric cancer progression |
Q42803494 | The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled |
Q37810502 | The tissue-specific stem cell as a target for chemoprevention |
Q36072943 | The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer |
Q53055743 | The tumor suppressor APC differentially regulates multiple β-catenins through the function of axin and CKIα during C. elegans asymmetric stem cell divisions. |
Q39097606 | The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3β activity in cell growth of esophageal carcinoma |
Q38210024 | The ubiquitin-conjugating system: multiple roles in viral replication and infection |
Q36596696 | The vitamin D receptor as a therapeutic target |
Q37138638 | The vitamin D receptor in cancer |
Q38068918 | The way Wnt works: components and mechanism. |
Q37615918 | Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma |
Q36833275 | Therapeutic targeting of the p53 pathway in cancer stem cells. |
Q38416280 | Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques |
Q24295448 | Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity |
Q34674947 | Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche |
Q36099445 | Threonine 393 of beta-catenin regulates interaction with Axin |
Q36771868 | Tie-2 regulates the stemness and metastatic properties of prostate cancer cells. |
Q27010086 | Tissue engineering: from research to dental clinics |
Q52365303 | Tissue transglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche. |
Q36296335 | Tissue-specific tumorigenesis: context matters |
Q37282291 | Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer |
Q24314891 | Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains |
Q89810253 | Tracing tumorigenesis in a solid tumor model at single-cell resolution |
Q90352947 | Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma |
Q41697916 | Transcription factor TCF4 maintains the properties of human corneal epithelial stem cells |
Q37982837 | Transcription factor network regulating CD(+)CD8(+) thymocyte survival |
Q60922665 | Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells |
Q36570605 | Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer |
Q34875987 | Transcriptomic portrait of human Mesenchymal Stromal/Stem Cells isolated from bone marrow and placenta |
Q38904274 | Transgenic expression of a canonical Wnt inhibitor, kallistatin, is associated with decreased circulating CD19+ B lymphocytes in the peripheral blood |
Q54360289 | Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype. |
Q34205345 | Treatment of glioblastoma multiforme using a combination of small interfering RNA targeting epidermal growth factor receptor and β-catenin. |
Q36616513 | Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth |
Q33823652 | Tumor inhibition by sodium selenite is associated with activation of c-Jun NH2-terminal kinase 1 and suppression of beta-catenin signaling |
Q39425138 | Tumor microenvironment and noncoding RNAs as co-drivers of epithelial-mesenchymal transition and cancer metastasis. |
Q42502782 | Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling |
Q35914643 | Tumor suppressor function of RUNX3 in breast cancer |
Q49494144 | Tumor-infiltrating lymphocytes are associated with β-catenin overexpression in breast cancer. |
Q37774865 | Tumor-initiating and -propagating cells: cells that we would like to identify and control |
Q37606286 | Tumour-initiating cells: challenges and opportunities for anticancer drug discovery |
Q36324925 | Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity |
Q40084609 | Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis |
Q35193091 | Two Natural ent-kauranoids as Novel Wnt Signaling Inhibitors |
Q39830811 | Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells |
Q34978471 | Type I interferons link viral infection to enhanced epithelial turnover and repair. |
Q93131971 | USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation |
Q36601000 | Ubiquitin and ubiquitin-like proteins in cancer pathogenesis |
Q37520106 | Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection |
Q35079346 | Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing |
Q36907405 | Understanding and targeting cancer stem cells: therapeutic implications and challenges |
Q47069994 | Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo |
Q53089167 | Unravelling cancer stem cell potential. |
Q36558594 | Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions |
Q36580511 | Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin |
Q92254375 | Upregulation of non-canonical Wnt ligands and oxidative glucose metabolism in NASH induced by methionine-choline deficient diet |
Q38222159 | Using proteomics to unravel the mysterious steps of the HBV-life-cycle |
Q47732691 | Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response |
Q36889627 | Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers |
Q35096327 | Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer |
Q35879070 | Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases |
Q30179397 | VentX trans-activates p53 and p16ink4a to regulate cellular senescence |
Q46250945 | Verrucarin J inhibits ovarian cancer and targets cancer stem cells |
Q33999763 | Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer. |
Q38899864 | WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1. |
Q34591481 | WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors |
Q84914069 | WITHDRAWN: Molecular Characteristics of Bone Marrow Mesenchymal Stem Cells: An Appealing Source for Regenerative Medicine |
Q38456692 | WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis |
Q92422653 | WNT Signaling in Disease |
Q39049231 | WNT Signaling in Lung Aging and Disease. |
Q41074649 | WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death |
Q33917543 | WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling |
Q37277156 | WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth |
Q38660744 | WNT signaling in glioblastoma and therapeutic opportunities |
Q37212748 | WNT signalling in the immune system: WNT is spreading its wings |
Q42498835 | WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production |
Q37798975 | Wg signaling in Drosophila heart development as a pioneering model |
Q26825780 | What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway |
Q47801457 | What do polymorphisms tell us about the mechanisms of COPD? |
Q35195877 | Whole-exome sequencing of endometriosis identifies frequent alterations in genes involved in cell adhesion and chromatin-remodeling complexes |
Q37866140 | Wilms tumor--a renal stem cell malignancy? |
Q42200637 | Wingless signaling induces widespread chromatin remodeling of target loci. |
Q41771195 | Wingless/Wnt signal transduction requires distinct initiation and amplification steps that both depend on Arrow/LRP. |
Q28543359 | Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells |
Q53568356 | Wls promotes the proliferation of breast cancer cells via Wnt signaling. |
Q92315665 | Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children |
Q64229171 | Wnt Signaling Pathway Linked to Intestinal Regeneration via Evolutionary Patterns and Gene Expression in the Sea Cucumber |
Q90382654 | Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis |
Q39306017 | Wnt Signaling in Normal and Malignant Stem Cells |
Q90721202 | Wnt Signaling in Ovarian Cancer Stemness, EMT, and Therapy Resistance |
Q51766147 | Wnt Signalling in Intestinal Stem Cells: Lessons from Mice and Flies. |
Q30360502 | Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea. |
Q34232635 | Wnt activation is implicated in glioblastoma radioresistance |
Q35192737 | Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage. |
Q33267354 | Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer |
Q92177011 | Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells |
Q47901236 | Wnt and frizzled expression during regeneration of internal organs in the holothurian Eupentacta fraudatrix |
Q33248385 | Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis |
Q33280730 | Wnt expression in the adult rat subventricular zone after stroke |
Q33614955 | Wnt gene expression in human trabecular meshwork cells. |
Q34393633 | Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia |
Q35642680 | Wnt ligands regulate Tkv expression to constrain Dpp activity in the Drosophila ovarian stem cell niche |
Q35101885 | Wnt modulates MCL1 to control cell survival in triple negative breast cancer |
Q37026623 | Wnt modulating agents inhibit human cytomegalovirus replication |
Q34976628 | Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma |
Q39298930 | Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line |
Q34323825 | Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors |
Q50648164 | Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis. |
Q39709638 | Wnt proteins promote bone regeneration |
Q37305230 | Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells |
Q36430885 | Wnt signal transduction and the formation of the myocardium |
Q24641814 | Wnt signal transduction pathways |
Q35132203 | Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans |
Q37864083 | Wnt signaling and colon carcinogenesis: beyond APC. |
Q36702732 | Wnt signaling and human diseases: what are the therapeutic implications? |
Q34293036 | Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development |
Q34262857 | Wnt signaling in cancer |
Q51518956 | Wnt signaling in cancer. |
Q33360705 | Wnt signaling in dendritic cells: its role in regulation of immunity and tolerance |
Q34541487 | Wnt signaling in estrogen-induced lactotroph proliferation. |
Q91643281 | Wnt signaling in liver disease: emerging trends from a bibliometric perspective |
Q38219832 | Wnt signaling in osteosarcoma |
Q33274270 | Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures |
Q25257722 | Wnt signaling induces epithelial differentiation during cutaneous wound healing |
Q37198555 | Wnt signaling inhibits CTL memory programming |
Q53221750 | Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells. |
Q34892024 | Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation |
Q37376243 | Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. |
Q42546329 | Wnt signaling mediates pathological vascular growth in proliferative retinopathy |
Q33850074 | Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment |
Q48274790 | Wnt signaling pathway regulates differentiation of chicken embryonic stem cells into spermatogonial stem cells via Wnt5a. |
Q34578573 | Wnt signaling promotes regeneration in the retina of adult mammals. |
Q28741624 | Wnt signaling promotes reprogramming of somatic cells to pluripotency |
Q35138570 | Wnt signaling regulates hepatic metabolism |
Q24337717 | Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex |
Q24646716 | Wnt signaling, lgr5, and stem cells in the intestine and skin |
Q42566173 | Wnt signaling, stem cells, and cancer of the gastrointestinal tract |
Q37539422 | Wnt signalling and cancer stem cells. |
Q22000774 | Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours |
Q38055435 | Wnt signalling in kidney diseases: dual roles in renal injury and repair |
Q25256712 | Wnt signalling in lung development and diseases |
Q42321100 | Wnt signalling is a bi-directional vulnerability of cancer cells |
Q90192464 | Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells |
Q38874181 | Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. |
Q38221361 | Wnt-Notch signalling crosstalk in development and disease. |
Q37362237 | Wnt-induced proteolytic targeting |
Q30581875 | Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer |
Q37287025 | Wnt-signaling and senescence: A tug of war in early neoplasia? |
Q28077396 | Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches |
Q34006063 | Wnt/beta-catenin inhibits dental pulp stem cell differentiation. |
Q21195874 | Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma |
Q40020289 | Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis |
Q46160238 | Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure |
Q34959673 | Wnt/catenin signaling in adult stem cell physiology and disease |
Q35640118 | Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer |
Q64119442 | Wnt/β-Catenin Pathway Is Involved in Cadmium-Induced Inhibition of Osteoblast Differentiation of Bone Marrow Mesenchymal Stem Cells |
Q57478274 | Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs |
Q50435067 | Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor. |
Q37132716 | Wnt/β-catenin Signaling in Normal and Cancer Stem Cells. |
Q26823272 | Wnt/β-catenin signaling and disease |
Q38609596 | Wnt/β-catenin signaling in bone marrow niche. |
Q37878387 | Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming |
Q46344011 | Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production |
Q33945336 | Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway |
Q42495424 | Wnt/β-catenin signaling is critical for dedifferentiation of aged epidermal cells in vivo and in vitro |
Q46241724 | Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway |
Q39278906 | Wnt/β-catenin signaling pathway upregulates c-Myc expression to promote cell proliferation of P19 teratocarcinoma cells |
Q38807957 | Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance. |
Q24338743 | Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells |
Q35887244 | Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled |
Q34637692 | Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells |
Q34765411 | Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells. |
Q39095813 | Wnt16 is involved in intramembranous ossification and suppresses osteoblast differentiation through the Wnt/β-catenin pathway |
Q42156387 | Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain |
Q90136497 | Wnt3a protein overexpression predicts worse overall survival in laryngeal squamous cell carcinoma |
Q40062995 | Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells |
Q53292749 | Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins. |
Q33366930 | Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation |
Q36058721 | Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2. |
Q33604792 | Wnt5a Signaling in Normal and Cancer Stem Cells |
Q36002416 | Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation |
Q28590609 | Wnt5a inhibits the proliferation and melanogenesis of melanocytes |
Q41890684 | Wnt5a knock-out mouse as a new model of anorectal malformation |
Q44956652 | Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice |
Q39030481 | Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial-mesenchymal transition |
Q35256323 | Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence |
Q42706277 | Wnt5a/β-catenin signaling drives calcium-induced differentiation of human primary keratinocytes |
Q47158860 | Wnt6 influences the viability of mouse embryonic palatal mesenchymal cells via the β-catenin pathway |
Q24329073 | Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells |
Q39306487 | Wnts Are Expressed in the Ependymal Region of the Adult Spinal Cord |
Q36672661 | Wnts as ligands: processing, secretion and reception |
Q38172119 | Wnts in adult brain: from synaptic plasticity to cognitive deficiencies |
Q38833977 | Wogonoside inhibits angiogenesis in breast cancer via suppressing Wnt/β-catenin pathway |
Q38219611 | Wound infections and healing: are they contributing factors for carcinogenesis? |
Q33526741 | Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. |
Q37985651 | Xenopus: an ideal system for chemical genetics. |
Q24292724 | Yes and PI3K bind CD95 to signal invasion of glioblastoma |
Q89634242 | Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation |
Q53283058 | [Non-serrated precursor lesions of colorectal tumours]. |
Q54587716 | [Signaling and metabolic predispositions linked to the colorectal cancer]. |
Q53280241 | [The utilization and limitation of CD133 epitopes in lung cancer stem cells research]. |
Q33844856 | beta-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia |
Q28276987 | beta-catenin destruction complex: insights and questions from a structural perspective |
Q36645589 | dFoxO promotes Wingless signaling in Drosophila |
Q92998611 | dTcf/Pangolin suppresses growth and tumor formation in Drosophila |
Q57116044 | is a novel oncogenic prognostic biomarker in human glioblastoma |
Q34129574 | mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. |
Q34529305 | miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway |
Q49265258 | miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a. |
Q34299316 | miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling |
Q53553780 | miR-29a modulates tumor necrosis factor-α-induced osteogenic inhibition by targeting Wnt antagonists. |
Q38360083 | miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway |
Q61802785 | miR-600 inhibits lung cancer via downregulating the expression of METTL3 |
Q38742731 | miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7. |
Q35793683 | miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/β-catenin signalling pathway |
Q42034071 | p53 in the CNS: Perspectives on Development, Stem Cells, and Cancer |
Q34285194 | sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair |
Q34283057 | ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling |
Q36351212 | α-Catulin marks the invasion front of squamous cell carcinoma and is important for tumor cell metastasis |
Q34028517 | α-catenin. A tumor suppressor beyond adherens junctions |
Q47110007 | β-Catenin Accumulation Is Associated With Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-Renewal |
Q41644202 | β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells. |
Q37991708 | β-Catenin Signalling in Glioblastoma Multiforme and Glioma-Initiating Cells |
Q38796204 | β-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma |
Q35058248 | β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells |
Q87418047 | β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer |
Q34961818 | β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors |
Q39454255 | β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway |
Q54117203 | β-arrestin2 Affects Cardiac Progenitor Cell Survival through Cell Mobility and Tube Formation in Severe Hypoxia. |
Q39345531 | β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer |
Q34353437 | β-catenin contributes to lung tumor development induced by EGFR mutations |
Q34730103 | β-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells |
Q42315542 | β-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients |
Q37634132 | β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis |
Q52633614 | β-catenin is required in odontoblasts for tooth root formation. |
Q34265458 | β-catenin knockdown enhances the effects of fluorouracil in the breast cancer cell line MDA-MB-468. |
Q42976183 | β-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network |
Q35096982 | β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells |
Q39016072 | β-catenin regulates NF-κB activity via TNFRSF19 in colorectal cancer cells |
Q36706395 | β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases |
Q26821842 | β-catenin/TCF-1 pathway in T cell development and differentiation |
Q35012043 | β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma |
Q35083197 | βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin |
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