Wnt signalling in stem cells and cancer

scientific article (publication date: 14 April 2005)

Wnt signalling in stem cells and cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1029766632
P356DOI10.1038/NATURE03319
P3181OpenCitations bibliographic resource ID141884
P698PubMed publication ID15829953
P5875ResearchGate publication ID7907046

P2093author name stringClevers H
Reya T
P2860cites workOncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemiaQ22010579
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signallingQ24290355
Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2Q24307092
Identification of c-MYC as a target of the APC pathwayQ24310637
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assemblyQ24312910
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cellsQ24314491
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinomaQ24336272
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APCQ24336321
Illegitimate WNT signaling promotes proliferation of multiple myeloma cellsQ24568035
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
Stem cells, cancer, and cancer stem cellsQ27860878
A common human skin tumour is caused by activating mutations in beta-cateninQ28115245
Lessons from hereditary colorectal cancerQ28131788
Regulation of LEF-1/TCF transcription factors by Wnt and other signalsQ28141939
The Hedgehog and Wnt signalling pathways in cancerQ28189485
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skinQ28190343
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulationQ28200070
Wnt activates the Tak1/Nemo-like kinase pathwayQ28244920
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fateQ28287796
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesisQ28506650
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinBQ28508041
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1Q28513432
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanismQ28585177
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migrationQ28587140
Deletion of β-catenin impairs T cell developmentQ28587501
A role for Wnt signalling in self-renewal of haematopoietic stem cellsQ28592213
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4Q28592260
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CMLQ29614278
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitorQ29614622
Osteoblastic cells regulate the haematopoietic stem cell nicheQ29615007
Identification of the haematopoietic stem cell niche and control of the niche sizeQ29615008
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
Regulation of cerebral cortical size by control of cell cycle exit in neural precursorsQ29615158
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skinQ29616492
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient miceQ29618462
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signalingQ29619294
A molecular profile of a hematopoietic stem cell nicheQ30847561
The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cellsQ33199519
Translating stem and progenitor cell biology to the clinic: barriers and opportunitiesQ33846149
Gut instincts: thoughts on intestinal epithelial stem cellsQ33936387
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene winglessQ34166322
A direct measurement of the radiation sensitivity of normal mouse bone marrow cellsQ34249472
Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cellsQ34253556
The multifaceted Paneth cellQ34531936
Designer skin: lineage commitment in postnatal epidermisQ34616032
WNT signaling and lymphocyte developmentQ34619783
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cellsQ34792452
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.Q34870182
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.Q35079614
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.Q35122385
Revisiting the bulgeQ35739842
Wnt signaling in the stem cell nicheQ35838139
Signaling pathways in intestinal development and cancerQ35912854
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic miceQ36294220
Beta-catenin is dispensable for hematopoiesis and lymphopoiesisQ36399011
Use of transgenic mice to infer the biological properties of small intestinal stem cells and to examine the lineage relationships of their descendantsQ37610716
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.Q38343552
Canonical Wnt signals are essential for homeostasis of the intestinal epitheliumQ39895829
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancerQ40664922
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signalingQ40690911
Wnt signaling regulates hemopoiesis through stromal cells.Q40794241
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signalingQ40844523
Stem cells in gastrointestinal epithelium: numbers, characteristics and deathQ40849001
Epithelial cell migration in the intestineQ40950314
The complement of desmosomal plaque proteins in different cell typesQ41491027
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous systemQ44472635
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermisQ44572857
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signalingQ45065876
Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.Q47247972
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumoursQ47764649
AXIN1 mutations but not deletions in cerebellar medulloblastomasQ48399835
Wnt proteins promote neuronal differentiation in neural stem cell culture.Q51725683
Clonal analysis of mouse intestinal epithelial progenitors.Q53940112
An HMG-box-containing T-cell factor required for thymocyte differentiation.Q59058515
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cellsQ75236410
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissueQ79358419
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenanceQ81308407
P433issue7035
P407language of work or nameEnglishQ1860
P921main subjectWnt signaling pathwayQ155769
P304page(s)843-50
P577publication date2005-04-14
P1433published inNatureQ180445
P1476titleWnt signalling in stem cells and cancer
P478volume434

Reverse relations

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Q89519650Changes in the expression of Notch and Wnt signalling molecules in human endometrial cancer
Q33564920Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.
Q34203737Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker
Q33631227Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling
Q42396920Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism
Q30431314Chemical approaches to stem cell biology and therapeutics
Q39236963Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling.
Q82747382Chromatin code, local non-equilibrium dynamics, and the emergence of transcription regulatory programs
Q36988886Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells
Q90707564Chromatin regulation and dynamics in stem cells
Q37579448Chronic exposure of renal stem cells to inorganic arsenic induces a cancer phenotype
Q49344588Circuit Design Features of a Stable Two-Cell System.
Q37467572Cisplatin and TRAIL enhance breast cancer stem cell death
Q64923110Clinical Significance of Transcription Factor 7 (TCF7) as a Prognostic Factor in Gastric Cancer.
Q33669921Clinical Usefulness of Serum CYFRA 21-1 in Patients with Colorectal Cancer
Q38026464Clinical implication of targeting of cancer stem cells
Q48351294Clinical significance of epithelial-to-mesenchymal transition in laryngeal carcinoma: Its role in the different subsites.
Q50955886Clinical significance of lymphoid enhancer-binding factor 1 expression in acute myeloid leukemia.
Q35040935Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients
Q45786900Co-activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer
Q60050019Co-treatment of tumor cells with hyaluronan plus doxorubicin affects endothelial cell behavior independently of VEGF expression
Q36319940Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation
Q41860950Colon Cancer Stem Cells: Bench-to-Bedside-New Therapeutical Approaches in Clinical Oncology for Disease Breakdown.
Q28391219Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture
Q42277641Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy
Q28222785Colorectal cancer prevention: choosing the most effective population strategy using bio-mathematical approaches
Q35597715Colorectal cancer prognosis: is it all mutation, mutation, mutation?
Q37962652Colorectal cancer stem cell: a potential therapeutic target
Q37183760Colorectal carcinogenesis: Review of human and experimental animal studies
Q92173125Combination of the natural compound Periplocin and TRAIL induce esophageal squamous cell carcinoma apoptosis in vitro and in vivo: Implication in anticancer therapy
Q47141878Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis
Q39044438Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction
Q35189046Comparing a discrete and continuum model of the intestinal crypt
Q37215425Comparison of Osteogenesis between Adipose-Derived Mesenchymal Stem Cells and Their Sheets on Poly-ε-Caprolactone/β-Tricalcium Phosphate Composite Scaffolds in Canine Bone Defects
Q36010516Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer
Q33869158Complex interactions between GSK3 and aPKC in Drosophila embryonic epithelial morphogenesis
Q55476361Composite Scaffolds Based on Intestinal Extracellular Matrices and Oxidized Polyvinyl Alcohol: A Preliminary Study for a New Regenerative Approach in Short Bowel Syndrome.
Q34063075Computational analysis of expression of human embryonic stem cell-associated signatures in tumors.
Q50123249Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment.
Q36515815Conditional switches for extracellular matrix patterning in Drosophila melanogaster
Q43167823Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow
Q26785528Connections between cadherin-catenin proteins, spindle misorientation, and cancer
Q55462530Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin.
Q34071276Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations
Q35746042Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors
Q47310367Constructing cellular niche properties by localized presentation of Wnt proteins on synthetic surfaces.
Q64089643Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis
Q52903652Contribution of EVX1 in Aggressiveness of Esophageal Squamous Cell Carcinoma.
Q34541595Contribution of TIP30 to chemoresistance in laryngeal carcinoma
Q37980722Controlling the stem cell compartment and regeneration in vivo: the role of pluripotency pathways
Q37552660Controversies in cancer stem cells: targeting embryonic signaling pathways
Q35543017Convergence of 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A and glycogen synthase kinase-3beta/beta-catenin signaling in corpus luteum progesterone synthesis
Q35906261Cooperation between Wnt and Notch signalling in human breast cancer.
Q39865463Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains
Q39301953Coordinated action of hypoxia-inducible factor-1α and β-catenin in androgen receptor signaling
Q37571557Copy number variation of the APC gene is associated with regulation of bone mineral density
Q42091512Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma.
Q36428279Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
Q52715797Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis.
Q34677454Crosstalk of Oncogenic Signaling Pathways during Epithelial-Mesenchymal Transition
Q36790604Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells
Q27650057Crystal Structure of a Full-Length β-Catenin
Q27677080Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment
Q27674857Crystal structures of the extracellular domain of LRP6 and its complex with DKK1
Q62698534Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling
Q41670781Curcumin reduces mitomycin C resistance in breast cancer stem cells by regulating Bcl-2 family-mediated apoptosis
Q52679071Current Insights into Oral Cancer Epigenetics.
Q39995485Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling
Q38101024Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter
Q36903109DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer.
Q57753463DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene
Q38913352DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis
Q35624893DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo
Q53508275DNA Hypermethylation of SHISA3 in Colorectal Cancer: An Independent Predictor of Poor Prognosis.
Q53830978DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features.
Q37276254DOXIL when combined with Withaferin A (WFA) targets ALDH1 positive cancer stem cells in ovarian cancer
Q24302441Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
Q24329167Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus
Q79777489Darwinian medicine: a case for cancer
Q24657713Dazap2 modulates transcription driven by the Wnt effector TCF-4
Q36927321Declaration of patent applications as financial interests: a survey of practice among authors of papers on molecular biology in Nature
Q39732013Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth
Q35695511Dedifferentiation of patient-derived glioblastoma multiforme cell lines results in a cancer stem cell-like state with mitogen-independent growth
Q30447391Deep tissue fluorescence imaging and in vivo biological applications
Q34700590Defective osteogenic differentiation in the development of osteosarcoma
Q39904972Defensin-immunology in inflammatory bowel disease
Q33891944Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells
Q36251554Defining the molecular nexus of cancer, type 2 diabetes and cardiovascular disease
Q36821221Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.
Q34228323Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading
Q55088439Demyelination in Multiple Sclerosis: Reprogramming Energy Metabolism and Potential PPARγ Agonist Treatment Approaches.
Q52629170Depleting ovarian cancer stem cells with calcitriol.
Q42802134Depletion of tumor suppressor Kank1 induces centrosomal amplification via hyperactivation of RhoA.
Q38588880Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia.
Q40088682Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification
Q36176784Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis.
Q35110734Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).
Q24318750Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
Q36672276Development and differentiation of neural rosettes derived from human embryonic stem cells
Q26781898Development of anticancer agents targeting the Wnt/β-catenin signaling
Q26739045Developmental Drift and the Role of Wnt Signaling in Aging
Q51951704Developmental biology: Our fly cousins' gut.
Q37000634Developmental signaling pathways in brain tumor-derived stem-like cells.
Q26766266Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer
Q38824254Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
Q35544524Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
Q39897131Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population
Q48148598Developmentally regulated signaling pathways in glioma invasion.
Q33829495Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer
Q39459014Dickkopf 4 positively regulated by the thyroid hormone receptor suppresses cell invasion in human hepatoma cells
Q64999289Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression.
Q34018958Dickkopf1 regulates fate decision and drives breast cancer stem cells to differentiation: an experimentally supported mathematical model
Q47753175Dietary Regulation of Adult Stem Cells.
Q37728998Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-Regulation
Q35106746Different requirements for Wnt signaling in tongue myogenic subpopulations
Q36652783Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
Q42469771Differential expression of basal microRNAs' patterns in human dental pulp stem cells
Q54294158Differential gene expression of Wnt signaling pathway in benign, premalignant, and malignant human breast epithelial cells.
Q92354388Differential regulation of myc homologs by Wnt/β-Catenin signaling in the early metazoan Hydra
Q50216018Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts.
Q34249028Differentiated epidermal cells regain the ability to regenerate a skin equivalent by increasing the level of β-catenin in the cells
Q52622302Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer.
Q33889275Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept
Q98505940Differentiation of cancer stem cells using synthetic small molecules: toward new therapeutic strategies against therapy resistance
Q50778004Diffusion- and convection-based activation of Wnt/β-catenin signaling in a gradient generating microfluidic chip.
Q34506361Dimethyloxalylglycine prevents bone loss in ovariectomized C57BL/6J mice through enhanced angiogenesis and osteogenesis
Q38989123Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β.
Q34182342Discovering dysfunction of multiple microRNAs cooperation in disease by a conserved microRNA co-expression network
Q58762810Discovery of Potent Disheveled/Dvl Inhibitors Using Virtual Screening Optimized With NMR-Based Docking Performance Index
Q39081836Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection
Q36582366Diseases of Wnt signaling
Q35587229Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas
Q38737124Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia
Q33763825Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.
Q37706466Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway
Q38015669Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments
Q35653963Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia
Q49937490Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors.
Q40219129Distinct nuclear arrangement of active and inactive c-myc genes in control and differentiated colon carcinoma cells
Q38634944Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells.
Q35641656Dormant Wnt-initiated mammary cancer can participate in reconstituting functional mammary glands
Q53589257Down-regulation of Frizzled-7 expression inhibits migration, invasion, and epithelial-mesenchymal transition of cervical cancer cell lines.
Q92803223Down-regulation of SLC35C1 induces colon cancer through over-activating Wnt pathway
Q64057521Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
Q43068054Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway
Q64068495Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma
Q35237732Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines
Q41387605Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
Q39149024Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas
Q97537814Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles
Q37840943Drug discovery approaches to target Wnt signaling in cancer stem cells
Q28473512Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties
Q38012254Drugging Wnt signalling in cancer
Q42651004Dual role of wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila
Q34478110Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls
Q41820010Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea
Q57027256Dynamics of WNT signaling components in the human ovary from development to adulthood
Q40303500Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling
Q37274623Dysregulated molecular networks in head and neck carcinogenesis
Q54334679Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1.
Q33968068E-cadherin acts as a regulator of transcripts associated with a wide range of cellular processes in mouse embryonic stem cells
Q40337889E-cadherin modulates Wnt-dependent transcription in colorectal cancer cells but does not alter Wnt-independent gene expression in fibroblasts
Q39588984EBV-encoded LMP1 increases nuclear β-catenin accumulation and its transcriptional activity in nasopharyngeal carcinoma
Q39698204EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis
Q50992137ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.
Q37520284EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling
Q98224541Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis
Q52011383Ectopic sebaceous gland: a developmental anomaly.
Q46524597Effect of Dietary-Resistant Starch on Inhibition of Colonic Preneoplasia and Wnt Signaling in Azoxymethane-Induced Rodent Models
Q61443707Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes
Q27309004Effect of doxorubicin/pluronic SP1049C on tumorigenicity, aggressiveness, DNA methylation and stem cell markers in murine leukemia
Q35815397Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis
Q52885276Effects of Dietary Resistant Starch on the Wnt Signaling Pathway and Preneoplastic Cells in the Colons of Azoxymethane-Treated Rats.
Q50518034Effects of Wnt/β-catenin signalling on proliferation and differentiation of apical papilla stem cells.
Q45853845Effects of a glycogen synthase kinase-3β inhibitor (LiCl) on c-myc protein in intervertebral disc cells
Q35676086Effects of age and gender on WNT gene expression in human bone marrow stromal cells
Q47744057Effects of genetic variants of the bovine WNT8A gene on nine important growth traits in beef cattle
Q36474269Effects of growth factors and cytokines on osteoblast differentiation.
Q37607632Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals
Q35041516Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling.
Q36485786Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1
Q35948915Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs
Q28272256Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms
Q38013550Embryonic stem cell markers.
Q48189669Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer
Q99406913Emerging Roles of Wnt Ligands in Human Colorectal Cancer
Q36374633Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy
Q33351225En1 and Wnt signaling in midbrain dopaminergic neuronal development
Q36956908Endocytosis: a positive or a negative influence on Wnt signalling?
Q39026766Endometrial Carcinoma: Specific Targeted Pathways.
Q33788010Enhanced cancer stem cell properties of a mitotically quiescent subpopulation of p75NTR-positive cells in esophageal squamous cell carcinoma
Q39231721Enrichment of Oct3/4-positive cells from a human bronchial epithelial cell line
Q52313815Enteric Nervous System Regulation of Intestinal Stem Cell Differentiation and Epithelial Monolayer Function.
Q34551512Enteric bacteria and cancer stem cells
Q38014664EpCAM and its potential role in tumor-initiating cells
Q35086401EpCAM and the biology of hepatic stem/progenitor cells
Q35745241EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy
Q30493364EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
Q40095580Epidermal growth factor inhibits glycogen synthase kinase-3 (GSK-3) and beta-catenin transcription in cultured ARPE-19 cells
Q45388856Epidermal homeostasis and radiation responses in a multiscale tissue modeling framework
Q24654755Epidermal homeostasis: a balancing act of stem cells in the skin
Q38111202Epidermal stem cells in orthopaedic regenerative medicine
Q36528809Epidermal stem cells of the skin
Q35853581Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.
Q37132659Epigenetic gene silencing in the Wnt pathway in breast cancer
Q40200349Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia
Q37858414Epigenetic regulation of aging stem cells
Q37626242Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages
Q34505232Epigenetics of prostate cancer: beyond DNA methylation
Q35960157Epithelial cell adhesion molecule in human hepatocellular carcinoma cell lines: a target of chemoresistence
Q33726440Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells
Q37213607Epithelial morphogenesis and intestinal cancer: new insights in signaling mechanisms
Q37425030Epithelial polarity: interactions between junctions and apical-basal machinery
Q33916933Epithelial repair mechanisms in the lung
Q36690919Epithelial stem cells: turning over new leaves
Q57283456Epithelial-mesenchymal transition and cancer stem cells: at the crossroads of differentiation and dedifferentiation
Q35884866Epithelial-mesenchymal transition in oral squamous cell carcinoma
Q42555042Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon
Q35006301Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal development
Q34006736Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory.
Q36382713Establishment and functioning of intrathymic microenvironments.
Q34335928Estrogen leads to reversible hair cycle retardation through inducing premature catagen and maintaining telogen
Q33358936Estrogens and stem cells in thyroid cancer
Q37395071Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study
Q35082943Evidence for involvement of Wnt signalling in body polarities, cell proliferation, and the neuro-sensory system in an adult ctenophore
Q33829820Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy
Q34690600Evidence for tankyrases as antineoplastic targets in lung cancer.
Q34387784Evidence for the importance of personalized molecular profiling in pancreatic cancer
Q53631163Evidence that the canonical Wnt signalling pathway regulates deer antler regeneration.
Q36209797Exendin-4 Inhibits Hepatic Lipogenesis by Increasing β-Catenin Signaling
Q36000159Exogenous high-mobility group box 1 protein injection improves cardiac function after myocardial infarction: involvement of Wnt signaling activation
Q51422684Exosomes Derived From Hypoxic Colorectal Cancer Cells Promote Angiogenesis Through Wnt4-Induced β-Catenin Signaling in Endothelial Cells.
Q90751055Exosomes Derived from Hypoxic Colorectal Cancer Cells Transfer Wnt4 to Normoxic Cells to Elicit a Prometastatic Phenotype
Q46359599Expression Levels and Localizations of DVL3 and sFRP3 in Glioblastoma
Q28588826Expression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strain
Q43298907Expression of Axin2 indicates a role for canonical Wnt signaling in development of the crown and root during pre- and postnatal tooth development
Q34126349Expression of GPR177 (Wntless/Evi/Sprinter), a highly conserved Wnt-transport protein, in rat tissues, zebrafish embryos, and cultured human cells
Q39692933Expression of Oct4 in HCC and modulation to wnt/β-catenin and TGF-β signal pathways
Q35101935Expression of Reg family proteins in embryonic stem cells and its modulation by Wnt/beta-catenin signaling.
Q44603877Expression of SRY-related HMG Box Transcription Factors (Sox) 2 and 9 in Craniopharyngioma Subtypes and Surrounding Brain Tissue
Q90221130Expression of WNT1 in ameloblastoma and its significance
Q50656448Expression of Wnt5a during development of anorectal malformations in a rat model of prenatal exposure to di(n-butyl) phthalate.
Q43108806Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream
Q44131003Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma.
Q37536514Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck
Q41931949Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1.
Q36817102Expression patterns of Wnt signaling component, secreted frizzled‑related protein 3 in astrocytoma and glioblastoma.
Q39587433Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates.
Q24311824Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells
Q33526036Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
Q28577689Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors
Q33282863Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells
Q58576736FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer
Q89909161FGF9 promotes cisplatin resistance in colorectal cancer via regulation of Wnt/β-catenin signaling pathway
Q92243283FK506 prevented bone loss in streptozotocin-induced diabetic rats via enhancing osteogenesis and inhibiting adipogenesis
Q90576943FRAT1 Enhances the Proliferation and Tumorigenesis of CD133+Nestin+ Glioma Stem Cells In Vitro and In Vivo
Q42436467FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in esophageal squamous cell carcinoma
Q34007808FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.
Q39550398FZD7 has a critical role in cell proliferation in triple negative breast cancer
Q27022335Factors and networks that underpin early hematopoiesis
Q39575199Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation
Q36216463Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation
Q33530092Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.
Q38193721Fat and bone interactions
Q37097913Feedback Regulation in a Cancer Stem Cell Model can Cause an Allee Effect.
Q41124448Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway
Q28484908Fibroblast growth factor receptor-mediated activation of AKT-β-catenin-CBP pathway regulates survival and proliferation of murine hepatoblasts and hepatic tumor initiating stem cells
Q26744082Fibroepithelioma of Pinkus Revisited
Q36348751Filtering transcriptional noise during development: concepts and mechanisms
Q54484446Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.
Q48607312FoxM1 is vital in the Wnt/β-catenin signaling pathogenesis of gliomas.
Q36059801Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors
Q24337018Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability
Q41817349Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors
Q39001461Frequent hypermethylation of WNT pathway genes in laryngeal squamous cell carcinomas
Q40081347Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas
Q37297579Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer
Q35086896Friend or foe: Endoplasmic reticulum protein 29 (ERp29) in epithelial cancer
Q37649858Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells.
Q41256855Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas.
Q36545508Frizzled-7 promoter is highly active in tumors and promoter-driven Shiga-like toxin I inhibits hepatocellular carcinoma growth
Q34788226Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer.
Q48093281Frizzled7 Antibody-Functionalized Nanoshells Enable Multivalent Binding for Wnt Signaling Inhibition in Triple Negative Breast Cancer Cells.
Q26849278Frizzled7 as an emerging target for cancer therapy
Q38234418From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
Q38213433From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.
Q34977317From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging.
Q36964320Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer
Q43006045Function following form: functional differentiation of mammary epithelial cells requires laminin-induced polarization of PI3-kinase
Q37595930Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer
Q37372272Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin
Q24320123Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells
Q64939214Functional link between plasma membrane spatiotemporal dynamics, cancer biology, and dietary membrane-altering agents.
Q28508864Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice
Q37772128G-protein coupled receptors in stem cell self-renewal and differentiation.
Q37200841G-protein-coupled receptors and melanoma
Q35920539GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment
Q37601318GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?
Q48299832GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen
Q46228676GLI1, CTNNB1 and NOTCH1 protein expression in a thymic epithelial malignancy tissue microarray
Q42453322GSK3beta affects apical-basal polarity and cell-cell adhesion by regulating aPKC levels
Q37596883GSK3β activity is essential for senescence-associated heterochromatin foci (SAHF) formation induced by HMGA2 in WI38 cells
Q36561625GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma
Q35741579Galectin-3 augments tumor initiating property and tumorigenicity of lung cancer through interaction with β-catenin
Q39252635Galectin-3 gene silencing inhibits migration and invasion of human tongue cancer cells in vitro via downregulating β-catenin
Q38714564Gankyrin regulates cell signaling network
Q47661011Gankyrin: a novel promising therapeutic target for hepatocellular carcinoma
Q39292672Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer
Q41894790Gene expression of growth signaling pathways is up-regulated in CD133-positive medulloblastoma cells
Q54416904Gene expression patterns in the bone tissue of women with fibrous dysplasia
Q84874923Gene expression profiling in mouse liver infected with Clonorchis sinensis metacercariae
Q28285016Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals
Q21135589Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway
Q36656474Genetic Variants in the Wnt Signaling Pathway Are Not Associated with Survival Outcome of Non-Small Cell Lung Cancer in a Korean Population
Q54458047Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report.
Q35069181Genetic interaction analysis of TCF7L2 for biochemical recurrence after radical prostatectomy in localized prostate cancer.
Q37350419Genetic models of cancer in zebrafish
Q37696169Genetic polymorphisms of Wnt/β-catenin pathway genes are associated with the efficacy and toxicities of radiotherapy in patients with nasopharyngeal carcinoma
Q33705233Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients
Q39286333Genetics of Adrenocortical Development and Tumors
Q37377851Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways
Q33591835Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method
Q36259297Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs
Q39606660Genome-wide screen reveals WNT11, a non-canonical WNT gene, as a direct target of ETS transcription factor ERG.
Q35225219Genome-wide sequence and functional analysis of early replicating DNA in normal human fibroblasts
Q44255021Genomic compartmentalization of gene families encoding core components of metazoan signaling systems
Q68691877Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis.
Q37699112Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs.
Q37127231Getting to the stem of chronic myeloid leukaemia
Q38118310Ghost cells: A journey in the dark….
Q38043203Ghrelin O-acyltransferase assays and inhibition
Q91639231Ginsenoside Rh2 activates α-catenin phosphorylation to inhibit lung cancer cell proliferation and invasion
Q55358019Glioblastoma-targeted CD4+ CAR T cells mediate superior antitumor activity.
Q37752381Glioma stem cell signaling: therapeutic opportunities and challenges
Q61451737Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods
Q39395261Global methylation profiling to identify epigenetic signature of gallbladder cancer and gallstone disease.
Q34050208Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor
Q24307581Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation
Q41481540Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling
Q33710200Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death
Q38945181Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth.
Q43105986Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging
Q37698255Gradients in planarian regeneration and homeostasis
Q28478455Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells
Q41432008Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming
Q42440768Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation
Q64260986HDAC I inhibitor regulates RUNX2 transactivation through canonical and non-canonical Wnt signaling in aortic valvular interstitial cells
Q33976964HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.
Q24337920HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies
Q35919080HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis
Q39018737HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice
Q37362117HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer
Q64912081HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations.
Q39514539HSulf-1 inhibits cell proliferation and invasion in human gastric cancer
Q99607499Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling
Q54154094Healing efficacy of fracture-targeted GSK3β inhibitor-loaded micelles for improved fracture repair.
Q35070272Heat shock proteins in breast cancer progression--a suitable case for treatment?
Q36596124HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.
Q57615464Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
Q41814485Hematopoietic stem cell development requires transient Wnt/β-catenin activity
Q37708991Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase
Q50859715Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.
Q38788971Hepatic cancer stem cell marker granulin-epithelin precursor and β-catenin expression associate with recurrence in hepatocellular carcinoma
Q60920093Hepatitis C virus core protein modulates several signaling pathways involved in hepatocellular carcinoma
Q50490409Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon.
Q36244287High Dickkopf-1 expression is associated with poor prognosis in patients with advanced urothelial carcinoma.
Q37225362High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid
Q41876961High Levels of Canonical Wnt Signaling Lead to Loss of Stemness and Increased Differentiation in Hematopoietic Stem Cells
Q45770808High levels of β-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway
Q38608910High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells
Q35049311High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A.
Q41696798High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars.
Q37457650Homeobox protein VentX induces p53-independent apoptosis in cancer cells
Q37014671Host-microbe interaction: mechanisms of defensin deficiency in Crohn's disease.
Q24305517Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements
Q35147451Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells
Q40299676Human sebaceous tumors harbor inactivating mutations in LEF1.
Q60953217Hypermethylated and its clinical significance in colorectal cancer
Q58583093Hypermethylation of Secreted Frizzled Related Protein 1 gene promoter in different astrocytoma grades
Q44041187Hypervascular hepatocellular carcinomas showing hyperintensity on hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance imaging: a possible subtype with mature hepatocyte nature.
Q38609714Hypoxia stimulates neural stem cell proliferation by increasing HIF‑1α expression and activating Wnt/β-catenin signaling
Q39564222Hypoxia-induced β-catenin downregulation involves p53-dependent activation of Siah-1.
Q37629893Hypoxia-inducible factors in stem cells and cancer
Q33670820Hypoxic tumor microenvironment and cancer cell differentiation
Q38659248ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
Q36916291IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer
Q39030617ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.
Q35973324Id2 deletion attenuates Apc-deficient ileal tumor formation
Q44756074Identification and validation that up-expression of HOXA13 is a novel independent prognostic marker of a worse outcome in gastric cancer based on immunohistochemistry
Q28548040Identification of New Candidate Genes and Chemicals Related to Esophageal Cancer Using a Hybrid Interaction Network of Chemicals and Proteins
Q39637431Identification of carbonic anhydrase 9 as a contributor to pingyangmycin-induced drug resistance in human tongue cancer cells
Q51608321Identification of carcinogenic potential-associated molecular mechanisms in CD133(+) A549 cells based on microRNA profiles.
Q30481751Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS
Q33735853Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo
Q34977426Identification of novel mutations by exome sequencing in African American colorectal cancer patients
Q33412050Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening
Q55530715Identification of proteins with potential osteogenic activity present in the water-soluble matrix proteins from Crassostrea gigas nacre using a proteomic approach.
Q28131701Identification of stem cells in small intestine and colon by marker gene Lgr5
Q34168146Identification of transcription factors regulating CTNNAL1 expression in human bronchial epithelial cells
Q36173081Identifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach
Q30481466Imaging hematopoietic precursor division in real time
Q38225580Imaging, genetic testing, and biomarker assessment of follicular cell-derived thyroid cancer
Q91897107Immunoexpression of LGR4 and Β-Catenin in Gastric Cancer and Normal Gastric Mucosa
Q90004966Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend
Q92768544Immunometabolism: A new target for improving cancer immunotherapy
Q36799983Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics
Q93080888Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors
Q35773743Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology
Q34062409Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells
Q30392749In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1
Q37305066In search of adrenocortical stem and progenitor cells
Q28076101In vitro models of cancer stem cells and clinical applications
Q36934236In vitro organoid culture of primary mouse colon tumors
Q36837034In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model
Q49095061In vivo tracing of canonical Wnt signaling in Xenopus tadpoles by means of an inducible transgenic reporter tool.
Q45268115Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway
Q37260274Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients
Q35105262Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans
Q47743734Increased expression of TBX2 is a novel independent prognostic biomarker of a worse outcome in colorectal cancer patients after curative surgery and a potential therapeutic target
Q33792932Increased expression of colonic Wnt9A through Sp1-mediated transcriptional effects involving arylsulfatase B, chondroitin 4-sulfate, and galectin-3
Q34802543Increased levels of β-catenin, LEF-1, and HPA-1 correlate with poor prognosis for acral melanoma with negative BRAF and NRAS mutation in BRAF exons 11 and 15 and NRAS exons 1 and 2.
Q36139562Increased nuclear β-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia
Q48895485Increased β-catenin/Tcf signaling in pilocytic astrocytomas: a comparative study to distinguish pilocytic astrocytomas from low-grade diffuse astrocytomas.
Q37407662Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.
Q34326719Indirect effects of Wnt3a/β-catenin signalling support mouse spermatogonial stem cells in vitro
Q53077914Indole-3-Carbinol Promotes Goblet-Cell Differentiation Regulating Wnt and Notch Signaling Pathways AhR-Dependently.
Q50802085Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.
Q39532407Induction of Wnt/β-catenin signaling in mouse mesenchymal stem cells is associated with activation of the p130 and E2f4 and formation of the p130/Gsk3β/β-catenin complex
Q35628160Induction of cancer cell death by isoflavone: the role of multiple signaling pathways
Q35082180Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis
Q64110671Infection in Chronic Inflammation and Gastrointestinal Cancer
Q38246263Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage
Q42469909Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells
Q57091284Inhibition of GSK3 and MEK induced cancer stem cell generation via the Wnt and MEK signaling pathways
Q35995911Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D.
Q37024249Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma
Q35538822Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells
Q34429613Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells
Q37058912Inhibition of Wnt Signaling by Silymarin in Human Colorectal Cancer Cells
Q43042100Inhibition of Wnt signaling and cancer stem cells
Q35090349Inhibition of adipocytogenesis by canonical WNT signaling in human mesenchymal stem cells
Q33560729Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth
Q50157930Inhibition of miR-155, a therapeutic target for breast cancer, prevented in cancer stem cell formation.
Q48017617Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy.
Q99711034Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer
Q34481563Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling
Q44036647Inhibitory effect and mechanism of mesenchymal stem cells on liver cancer cells
Q50949314Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis.
Q37786633Innate antimicrobial immunity in inflammatory bowel diseases
Q42755826Inorganic polyphosphate promotes cyclin D1 synthesis through activation of mTOR/Wnt/β-catenin signaling in endothelial cells
Q33735255Input of microenvironmental regulation on colorectal cancer: role of the CCN family
Q35229856Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation
Q36732647Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation.
Q47343843Integrating expression-related SNPs into genome-wide gene- and pathway-based analyses identified novel lung cancer susceptibility genes.
Q35126460Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer
Q28084948Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma
Q41458214Integrative analysis of cancer-related signaling pathways
Q99207517Integrin-alpha-6+ Candidate stem cells are responsible for whole body regeneration in the invertebrate chordate Botrylloides diegensis
Q28283184Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia
Q24302002Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence
Q34239769Interactions between cancer stem cells and their niche govern metastatic colonization
Q33673605Intercellular transfer of proteins as identified by stable isotope labeling of amino acids in cell culture
Q30500268Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells
Q30434589Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells
Q62556688Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging
Q37083757Intestinal iron homeostasis and colon tumorigenesis
Q35085948Intestinal stem cells and stem cell-based therapy for intestinal diseases
Q34943574Intranodal palisaded myofibroblastoma: another mesenchymal neoplasm with CTNNB1 (β-catenin gene) mutations: clinicopathologic, immunohistochemical, and molecular genetic study of 18 cases
Q34796316Intratracheal instillation of high dose adenoviral vectors is sufficient to induce lung injury and fibrosis in mice
Q52653031Investigating a multigene prognostic assay based on significant pathways for Luminal A breast cancer through gene expression profile analysis.
Q98289965Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway
Q42735854Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia?
Q34625269Isolation and characterization of a population of stem-like progenitor cells from an atypical meningioma.
Q39055537Isolation, identification, and characterization of cancer stem cells: A review
Q26822956Keeping Wnt signalosome in check by vesicular traffic
Q37426789Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
Q47927511Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells
Q24299779Knocking down Wnt9a mRNA levels increases cellular proliferation
Q36579803Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival
Q35269425Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine
Q34375332LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
Q24329083LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element
Q35001290LEF1 identifies androgen-independent epithelium in the developing prostate
Q24313620LEF1 in androgen-independent prostate cancer: regulation of androgen receptor expression, prostate cancer growth, and invasion
Q24606839LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling
Q33740256LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy
Q38878616LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells
Q37249025Lack of Muc1-regulated beta-catenin stability results in aberrant expansion of CD11b+Gr1+ myeloid-derived suppressor cells from the bone marrow
Q37304378Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer
Q34751569Large scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells
Q30499308Lentivirus-mediated Wnt11 gene transfer enhances Cardiomyogenic differentiation of skeletal muscle-derived stem cells
Q30514843Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling
Q37904866Lessons from common markers of tumor-initiating cells in solid cancers
Q38118817Leukemia stem cells: Old concepts and new perspectives
Q36030989Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future Directions
Q34677521LgR5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett's esophagus?
Q92260940Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy
Q33767534Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis
Q53447869Lgr5 marks cycling, yet long-lived, hair follicle stem cells.
Q93004983Lgr6: From Stemness to Cancer Progression
Q85036285Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis
Q36496001Limbal stem cells, a review of their identification and culture for clinical use.
Q46488088Lineage-specific evolution of cnidarian Wnt ligands.
Q24301672Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)
Q34143422Linking cell signaling and the epigenetic machinery
Q24541453Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin
Q38640136Lipoprotein Receptor-related Protein 6 Signaling is Necessary for Vasculogenic Differentiation of Human Dental Pulp Stem Cells
Q33359570Liposomal packaging generates Wnt protein with in vivo biological activity
Q58776006Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway
Q33523529Lithium chloride regulates the proliferation of stem-like cells in retinoblastoma cell lines: a potential role for the canonical Wnt signaling pathway.
Q42795961Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases
Q37015746Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin
Q91822543Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of β-catenin/TCF/LEF signalling
Q38931957Liver metastatic disease: new concepts and biomarker panels to improve individual outcomes
Q37358938Liver stem cells and hepatocellular carcinoma
Q46224632Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice
Q79671125Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy
Q34577033Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes
Q43271997Long-term exposure to various types of dietary fat modulates acrylamide-induced preneoplastic lesions of colon mucosa through Wnt/beta-catenin signaling in rats
Q28579732Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats
Q83396650Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis
Q43099080Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis.
Q37208778Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype
Q35872096Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis
Q35042805Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice
Q36488720Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
Q34408171Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors
Q39859295Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy.
Q40521041Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Q34328494Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling
Q37629583Lung cancer stem cells: Molecular features and therapeutic targets
Q37718455Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia
Q91272463Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway
Q58700996Lysophosphatidic acid enhances breast cancer cells-mediated osteoclastogenesis
Q33786774Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling
Q24616764Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression
Q34277630MENA is a transcriptional target of the Wnt/beta-catenin pathway
Q39279697MMP7 is a target of the tumour-associated antigen EpCAM.
Q35879924MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells
Q52727524MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.
Q84039307Macrophage migration inhibitory factor is a direct target of HBP1-mediated transcriptional repression that is overexpressed in prostate cancer
Q36457006Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways
Q37818162Malignant melanoma: from cell kinetics to micrometastases
Q37130864Mammalian Nemo-like kinase enhances β-catenin-TCF transcription activity in human osteosarcoma and neuroblastoma cells.
Q35050344Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis
Q34574786Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells
Q37427798Management of the human mucosal defensive barrier: evidence for glycan legislation
Q37331003Mapping key features of transcriptional regulatory circuitry in embryonic stem cells.
Q46307051Mapping normal and cancer cell signalling networks: towards single-cell proteomics
Q51701356Mathematical modelling and experiments for the proliferation and differentiation of Drosophila intestinal stem cells I.
Q92537708Matrix Gla Protein Promotes the Bone Formation by Up-Regulating Wnt/β-Catenin Signaling Pathway
Q38412794Maturation of cortical bone suppresses periosteal osteoprogenitor proliferation in a paracrine manner
Q64955692Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer.
Q38088654Mechanisms of RAS/β-catenin interactions
Q36467836Mechanisms of disease: from stem cells to colorectal cancer.
Q30575713Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype
Q52569557Mediator is a transducer of Wnt/beta-catenin signaling.
Q51052629Melatonin Inhibits Neural Cell Apoptosis and Promotes Locomotor Recovery via Activation of the Wnt/β-Catenin Signaling Pathway After Spinal Cord Injury.
Q38197694Melatonin regulates mesenchymal stem cell differentiation: a review.
Q90588984Melatonin reverses nasopharyngeal carcinoma cisplatin chemoresistance by inhibiting the Wnt/β-catenin signaling pathway
Q48761731Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.
Q38650682Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5
Q34480237Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells
Q36296784Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling
Q36414996Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
Q42271898Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH.
Q34178502Methylated CpG site count of dapper homolog 1 (DACT1) promoter prediction the poor survival of gastric cancer
Q39254311Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome
Q35974424Methylation-mediated molecular dysregulation in clinical oral malignancy
Q37548379Methylprednisolone promotes recovery of neurological function after spinal cord injury: association with Wnt/β-catenin signaling pathway activation.
Q36014206Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression
Q37190321MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer
Q39393414MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling
Q35119958MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation
Q58698448MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loop
Q92276968MiR-509-5p improves the proliferative and invasive abilities of papillary thyroid carcinoma cells by inhibiting SFRP1
Q35172664MicroRNA MiR-199a-5p regulates smooth muscle cell proliferation and morphology by targeting WNT2 signaling pathway
Q26771792MicroRNA Regulation of Human Breast Cancer Stem Cells
Q90312107MicroRNA in Pancreatic Cancer: From Biology to Therapeutic Potential
Q38850617MicroRNA in pancreatic cancer
Q38696912MicroRNA-139-5p inhibits bladder cancer proliferation and self-renewal by targeting the Bmi1 oncogene
Q53504882MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7.
Q38804358MicroRNA-340 inhibits the migration, invasion, and metastasis of breast cancer cells by targeting Wnt pathway.
Q37317467MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway
Q35476764Microarray analysis of human adipose-derived stem cells in three-dimensional collagen culture: osteogenesis inhibits bone morphogenic protein and Wnt signaling pathways, and cyclic tensile strain causes upregulation of proinflammatory cytokine regul
Q38770592Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots.
Q36761864Microbial dysbiosis and colon carcinogenesis: could colon cancer be considered a bacteria-related disease?
Q37439314Microenvironmental independence associated with tumor progression
Q37890251Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
Q24653781Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11
Q43065072Minimizing the risk of cancer: tissue architecture and cellular replication limits
Q28730326Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice
Q27021818Mitotic and mitogenic Wnt signalling
Q36486600Mitotic spindle (DIS)orientation and DISease: cause or consequence?
Q33924425Modeling cell-cell interactions in regulating multiple myeloma initiating cell fate.
Q49805610Modeling the Role of Wnt Signaling in Human and Drosophila Stem Cells.
Q34032714Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts
Q48269479Models of human adamantinomatous craniopharyngioma tissue: Steps toward an effective adjuvant treatment.
Q37609953Modular Cre/lox system and genetic therapeutics for colorectal cancer
Q34405122Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity
Q34432431Modulating the stem cell niche for tissue regeneration
Q28079530Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer
Q35345488Modulation of canonical Wnt signaling by the extracellular matrix component biglycan
Q34707660Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila.
Q39800983Modulation of the tumor suppressor protein alpha-catenin by ischemic microenvironment.
Q37004224Molecular Genetics of Colorectal Cancer: An Overview
Q41446090Molecular Mechanism of β-Catenin Signaling Pathway Inactivation in ETV1-Positive Prostate Cancers
Q36501328Molecular basis for the tissue specificity of β-catenin oncogenesis.
Q33756006Molecular biology of liver cancer stem cells
Q36836733Molecular dissection of microsatellite instable colorectal cancer
Q21284820Molecular functions of thyroid hormones and their clinical significance in liver-related diseases
Q37962744Molecular mediators of mesenchymal stem cell biology
Q37763635Molecular pathways to CML stem cells
Q33422792Molecular profiling of conjunctival epithelial side-population stem cells: atypical cell surface markers and sources of a slow-cycling phenotype
Q34770823Molecular profiling predicts the existence of two functionally distinct classes of ovarian cancer stroma
Q37711271Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells
Q37176648Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy
Q33455595Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer
Q28749074Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathways
Q27311697Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells
Q38616107Moonlighting proteins in cancer.
Q24646903More than one way to skin . .
Q36830707Morphogens, morphostats, microarchitecture and malignancy
Q28475186Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.
Q47622665Msi2 plays a carcinogenic role in esophageal squamous cell carcinoma via regulation of the Wnt/β-catenin and Hedgehog signaling pathways
Q26752365Multiple myeloma cancer stem cells
Q35666438Musashi-2 promotes hepatitis Bvirus related hepatocellular carcinoma progression via the Wnt/β-catenin pathway.
Q34720637Mutated beta-catenin evades a microRNA-dependent regulatory loop
Q36447416Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.
Q28281731Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours
Q100958900Mutations and mechanisms of WNT pathway tumour suppressors in cancer
Q38694695Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells.
Q39170190Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells.
Q38246241Myeloma bone disease: pathogenesis, current treatments and future targets
Q50753352Myocardial structural protein expression in umbilical cord blood mesenchymal stem cells after myogenic induction.
Q34659995N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment
Q40009083NF-kappaB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells
Q37149896NKX6.3 Is a Transcription Factor for Wnt/β-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression
Q28477683Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin
Q38270098Nanomedicine strategies for hematological malignancies: what is next?
Q58708009Nanomedicines reveal how PBOV1 promotes hepatocellular carcinoma for effective gene therapy
Q36217643Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin
Q34999115Nanosecond pulsed electric field inhibits cancer growth followed by alteration in expressions of NF-κB and Wnt/β-catenin signaling molecules
Q42632502Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers
Q94481776Negative binomial additive model for RNA-Seq data analysis
Q80033357Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling
Q54265665Neuroblastoma
Q35837998Neuroprotective effect of rapamycin on spinal cord injury via activation of the Wnt/β-catenin signaling pathway
Q48588244New Advances and Challenges of Targeting Cancer Stem Cells.
Q33639180New Therapeutics Targeting Colon Cancer Stem Cells
Q37215989New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.
Q24680988New molecularly targeted therapies for lung cancer
Q39018424New perspectives for prostate cancer treatment: in vitro inhibition of LNCaP and PC3 cell proliferation by amnion-derived mesenchymal stromal cells conditioned media
Q36519041New therapies for hepatocellular carcinoma.
Q64951391Next Viable Routes to Targeting Pancreatic Cancer Stemness: Learning from Clinical Setbacks.
Q39587242Niche-less maintenance of HSCs by 2i
Q33500353No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer
Q37627063Nodal promotes the self-renewal of human colon cancer stem cells via an autocrine manner through Smad2/3 signaling pathway
Q42378466Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage
Q39454318Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage.
Q38189361Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation
Q39110080Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
Q41398559Non-thermal Plasma Causes p53-Dependent Apoptosis in Human Colon Carcinoma Cells.
Q31090776Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer
Q35821670Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche
Q28585201Noncanonical Wnt signaling promotes apoptosis in thymocyte development
Q38940107Noncanonical Wnt5a-Ca(2+) -NFAT signaling axis in pesticide induced bone marrow aplasia mouse model: A study to explore the novel mechanism of pesticide toxicity
Q36474886Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia
Q36480684Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses
Q37237414Notch and wingless signaling cooperate in regulation of dendritic cell differentiation
Q47220353Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression
Q37169972Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition
Q52670911Notch synergizes with axin to regulate the activity of armadillo in Drosophila.
Q52574734Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.
Q53317867Notch1 expression in colorectal carcinoma determines tumor differentiation status.
Q51979665Novel Robinow syndrome causing mutations in the proximal region of the frizzled-like domain of ROR2 are retained in the endoplasmic reticulum.
Q24676528Novel c-MYC target genes mediate differential effects on cell proliferation and migration
Q38114502Novel drug discovery opportunities for colorectal cancer
Q40176341Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway.
Q37738484Novel insights into the development of T-cell acute lymphoblastic leukemia.
Q35902006Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development
Q33343446Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
Q37198168Novel strategies targeting cancer stem cells through phytochemicals and their analogs
Q34289576Novel targets for prostate cancer chemoprevention
Q34940971Novel therapeutic strategies for targeting liver cancer stem cells
Q64964513Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs.
Q46047714Nuclear expression and gain-of-function β-catenin mutation in glomangiopericytoma (sinonasal-type hemangiopericytoma): insight into pathogenesis and a diagnostic marker.
Q87036473Nuclear expression of β-catenin predicts the efficacy of meloxicam treatment for patients with sporadic desmoid tumors
Q35831988Nuclear lamins: key regulators of nuclear structure and activities
Q24315870Nuclear signalling by tumour-associated antigen EpCAM
Q35684848Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation
Q39146122Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.
Q37279704Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology.
Q27026694Nutritional regulation of stem and progenitor cells in Drosophila
Q33913190O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41.
Q35129302O2 regulates stem cells through Wnt/β-catenin signalling.
Q34211306Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling
Q38705603Oct4 induces EMT through LEF1/β-catenin dependent WNT signaling pathway in hepatocellular carcinoma
Q48273193Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells.
Q34424883Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer.
Q35889072Oncogenesis and cancer stem cells: current opinions and future directions
Q35066337Oncogenesis and induced pluripotency - commonalities of signalling pathways
Q36043468Oncogenicity of the developmental transcription factor Sox9.
Q28576842Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons
Q81573645Opinion: the origin of the cancer stem cell: current controversies and new insights
Q42092681Opposite spectrum of activity of canonical Wnt signaling in the osteogenic context of undifferentiated and differentiated mesenchymal cells: implications for tissue engineering
Q47330933Oral Cancer Stem Cells Microenvironment.
Q21090715Organized emergence of multiple-generations of teeth in snakes is dysregulated by activation of Wnt/beta-catenin signalling
Q56556302Oridonin inhibits growth and induces apoptosis of human neurocytoma cells via the Wnt/β-catenin pathway
Q37861635Origin and maintenance of the intestinal cancer stem cell
Q36677501Original CIN: reviewing roles for APC in chromosome instability
Q36803600Osteosarcoma development and stem cell differentiation
Q37415611Ovarian cancer update: lessons from morphology, molecules, and mice
Q45989150Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.
Q36413067Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer.
Q37954295Overcoming multidrug resistance in human cancer cells by natural compounds
Q90465703Overexpression of HDAC6 suppresses tumor cell proliferation and metastasis by inhibition of the canonical Wnt/β-catenin signaling pathway in hepatocellular carcinoma
Q36334142Overexpression of HOXB7 is associated with a poor prognosis in patients with gastric cancer
Q36986217Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway
Q55690589Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus.
Q33791918Overexpression of Wnt5a promotes angiogenesis in NSCLC.
Q83729519Overexpression of nuclear NHERF1 in advanced colorectal cancer: association with hypoxic microenvironment and tumor invasive phenotype
Q36733465Oxygen sensing and redox signaling: the role of thioredoxin in embryonic development and cardiac diseases
Q42098686PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression
Q44554105PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers.
Q24654901PCAF acetylates {beta}-catenin and improves its stability
Q35107382PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing
Q64236663PIK3CD induces cell growth and invasion by activating AKT/GSK-3β/β-catenin signaling in colorectal cancer
Q24615768PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas
Q52352270PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Q38168831PP2A-Mediated Anticancer Therapy
Q91560799Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis
Q37952082Pancreatic cancer stem cell biology and its therapeutic implications
Q26741215Pancreatic cancer stem cell markers and exosomes - the incentive push
Q38516947Pancreatic cancer stem cells.
Q38180221Pancreatic gene variants potentially associated with dipeptidyl peptidase-4 inhibitor treatment response in Type 2 diabetes
Q51459248Paper-based microreactor array for rapid screening of cell signaling cascades.
Q37240573Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth
Q41088460Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation
Q35157066Parameter-free methods distinguish Wnt pathway models and guide design of experiments
Q37595673Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
Q38428260Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells
Q36644898Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy
Q64056913Penfluridol overcomes paclitaxel resistance in metastatic breast cancer
Q52625208Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.
Q24650730Ph+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cells
Q35619694Pharmacologic induction of CD8+ T cell memory: better living through chemistry
Q34892759Pharmacophore modeling, 3D-QSAR and DFT studies of IWR small-molecule inhibitors of Wnt response
Q38816754Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines
Q34091635Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis
Q36752069Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts
Q98513563Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
Q38023557Physiological functions of GPx2 and its role in inflammation-triggered carcinogenesis
Q35001181Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma
Q97568858Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells
Q37452373Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice.
Q38293612Pivotal role of pervasive neoplastic and stromal cells reprogramming in circulating tumor cells dissemination and metastatic colonization.
Q36924388Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling
Q38988584Plumbagin and Its Role in Chronic Diseases
Q42051646Plumbagin exhibits an anti-proliferative effect in human osteosarcoma cells by downregulating FHL2 and interfering with Wnt/β-catenin signalling
Q37122739Pluripotency and nuclear reprogramming
Q42259647Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity
Q37629613Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer
Q29619697Polycomb silencers control cell fate, development and cancer
Q36342403Polymer-drug conjugates for intracellar molecule-targeted photoinduced inactivation of protein and growth inhibition of cancer cells
Q37591364Ponatinib efficiently kills imatinib-resistant chronic eosinophilic leukemia cells harboring gatekeeper mutant T674I FIP1L1-PDGFRα: roles of Mcl-1 and β-catenin.
Q36775710Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552
Q57291734Posters
Q64118291Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling
Q35540034Potential of Mesenchymal Stem Cell based application in Cancer
Q42700663Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype
Q39122669Prdm5 suppresses Apc(Min)-driven intestinal adenomas and regulates monoacylglycerol lipase expression.
Q36989548Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.
Q35702897Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome.
Q36698501Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors
Q55038918Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer.
Q36482223Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation
Q35261950Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway
Q35130563Primary small cell carcinoma of the esophagus: clinicopathological study of 44 cases
Q37469714Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells
Q35324807Prognostic parameters for the primary care of melanoma patients: what is really risky in melanoma?
Q39635505Prognostic value of Wnt inhibitory factor-1 expression in hepatocellular carcinoma that is independent of gene methylation.
Q34976602Programming CD8+ T cells for effective immunotherapy.
Q38078312Progress in the reprogramming of somatic cells
Q35210449Prokineticin 1 induces Dickkopf 1 expression and regulates cell proliferation and decidualization in the human endometrium
Q91291212Propofol suppresses proliferation and migration of papillary thyroid cancer cells by down-regulation of lncRNA ANRIL
Q38020001Prorenin receptor regulates more than the renin-angiotensin system
Q34885515Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization
Q57138061Prostate cancer stem cells
Q34000532Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK).
Q24298111Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex
Q38826163Protein-Specific Imaging of O-GlcNAcylation in Single Cells.
Q33237312Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis.
Q39491823Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations.
Q26738712Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer
Q28510950Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
Q33925855Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia
Q37411863Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling
Q28476367Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling
Q33281138Qualitative networks: a symbolic approach to analyze biological signaling networks
Q35815971Quantitative Differences in Nuclear β-catenin and TCF Pattern Embryonic Cells in C. elegans
Q39836950Quantitative Phosphoproteomic Study Reveals that Protein Kinase A Regulates Neural Stem Cell Differentiation Through Phosphorylation of Catenin Beta-1 and Glycogen Synthase Kinase 3β.
Q59793350Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device
Q41886588Quercetin Confers Tumoricidal Activity Through Multipathway Mechanisms in A N-Methylnitrosourea Rat Model of Colon Cancer
Q37799253Quiescent, slow-cycling stem cell populations in cancer: a review of the evidence and discussion of significance
Q58572053R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells
Q91993511RCC2 promotes breast cancer progression through regulation of Wnt signaling and inducing EMT
Q33380402REST regulates distinct transcriptional networks in embryonic and neural stem cells
Q49456346RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1.
Q50054622RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance.
Q34628925RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.
Q36637143RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer
Q58695635Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness
Q35791224Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.
Q36629426Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells
Q43788473Radiofrequency ablation for dysplasia in Barrett's esophagus restores β-catenin activation within esophageal progenitor cells.
Q81113722Ratio of Wnt3a to BMP4 doses is critical to their synergistic effects on proliferation of differentiating mouse embryonic stem cells
Q89026179Re-Evaluating E-Cadherin and β-Catenin: A Pan-Cancer Proteomic Approach with an Emphasis on Breast Cancer
Q37271085Real-Time Analysis of Endogenous Wnt Signalling in 3D Mesenchymal Stromal Cells.
Q26797285Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models
Q35459525Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers
Q37197074Recent advances in cardiovascular regenerative medicine: the induced pluripotent stem cell era.
Q33730375Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies
Q33514162Recent data in adrenocortical tumorigenesis
Q37310063Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications
Q34507622Receptor heterodimerization as a novel mechanism for the regulation of Wnt/β-catenin signaling
Q92001056Receptor subtype discrimination using extensive shape complementary designed interfaces
Q33618799Reciprocal control of lncRNA-BCAT1 and β-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer
Q57279171Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4
Q34324645Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Q33884823Red Deer Antler Extract Accelerates Hair Growth by Stimulating Expression of Insulin-like Growth Factor I in Full-thickness Wound Healing Rat Model.
Q37699347Redox regulation of Wnt signalling via nucleoredoxin
Q35550094Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell-like phenotype
Q39134073Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules
Q63407739Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor
Q38852157Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.
Q64068191Regulation of Wnt Singaling Pathway by Poly (ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Lung Cancer in Mice Induced by Benzo(a)pyrene Inhalation Exposure
Q34576629Regulation of bone mass by Wnt signaling
Q37208020Regulation of dendritic cell differentiation in bone marrow during emergency myelopoiesis
Q38225994Regulation of hematopoietic and leukemic stem cells by the immune system.
Q38864687Regulation of metastasis of bladder cancer cells through the WNT signaling pathway
Q21284160Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells
Q35171019Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt.
Q26853096Regulation of ovarian cancer stem cells or tumor-initiating cells
Q37371602Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl
Q36972353Regulation of protumorigenic pathways by insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis
Q37707515Regulation of stem cell function by protein ubiquitylation
Q36288064Regulation of the adrenocortical stem cell niche: implications for disease
Q36229240Repression of BCL-6 is required for the formation of human memory B cells in vitro
Q41502015Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene
Q37343986Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells
Q35412202Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Q36742802Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers
Q30426494Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines
Q34418424Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
Q42377913Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.
Q42781875Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine
Q35837893Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway
Q37360869Retinoid signaling in control of progenitor cell differentiation during mouse development
Q36284219Retracted: Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation
Q39125214Review on the role of the human Polyomavirus JC in the development of tumors.
Q89658859Revisiting the Roles of Pro-Metastatic EpCAM in Cancer
Q37471296Rho GTPases in hematopoietic stem cell functions
Q33532622Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner
Q37012033Road for understanding cancer stem cells: model cell lines
Q57470592Role of AhR in Regulating Cancer Stem Cell-like Characteristics in Choriocarcinoma
Q43122590Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail.
Q34033323Role of Cripto-1 in stem cell maintenance and malignant progression
Q35804641Role of GAC63 in transcriptional activation mediated by beta-catenin
Q34055747Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme
Q51903398Role of Lef1 in sustaining self-renewal in mouse embryonic stem cells.
Q34697373Role of Notch and its oncogenic signaling crosstalk in breast cancer
Q92702508Role of Secreted Frizzled-Related Protein 1 in Early Mammary Gland Tumorigenesis and Its Regulation in Breast Microenvironment
Q39012183Role of Wnt5a in the Pathogenesis of Inflammatory Diseases.
Q24320028Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: regulation of lymphoid enhancer-binding factor 1
Q34259112Role of liver stem cells in hepatocarcinogenesis
Q28076798Role of nanotechnology and gene delivery systems in TRAIL-based therapies
Q38014421Role of the wnt pathway in thyroid cancer
Q37027389Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling.
Q34566517Roles of Wnt/β-catenin signaling in retinal neuron-like differentiation of bone marrow mesenchymal stem cells from nonobese diabetic mice
Q33695152Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
Q53348663Roots and stems: stem cells in cancer.
Q33385660Runx expression is mitogenic and mutually linked to Wnt activity in blastula-stage sea urchin embryos
Q89230444Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity
Q34659163Rutin mediated targeting of signaling machinery in cancer cells.
Q47747424SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis
Q24685799SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice
Q35939318SEL1L, an UPR response protein, a potential marker of colonic cell transformation
Q35097426SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway
Q28240835SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress
Q92433227SOX12 promotes the growth of multiple myeloma cells by enhancing Wnt/β-catenin signaling
Q42379103SOX15 regulates proliferation and migration of endometrial cancer cells
Q37689061SOX17 is a tumor suppressor in endometrial cancer
Q42969109SOX9 Is Highly Expressed in Nonampullary Duodenal Adenoma and Adenocarcinoma in Humans
Q42404921SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.
Q53224289SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans.
Q37041810STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation.
Q36195433Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133(+) human colorectal cancer cells
Q90190759Salinomycin-Loaded Iron Oxide Nanoparticles for Glioblastoma Therapy
Q39432450Salinomycin: a new cancer drug candidate
Q26853644Salinomycin: a novel anti-cancer agent with known anti-coccidial activities
Q33693378Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway
Q89681983Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway
Q36295027Sca-1 knockout impairs myocardial and cardiac progenitor cell function
Q47561285Scarless wound healing: Transitioning from fetal research to regenerative healing
Q33703825Secreted frizzled-related protein 4: an angiogenesis inhibitor.
Q42040756Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Q39098971Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen
Q36040176Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage
Q61809837Self-antigen MASH2 combined with the AS15 immunostimulant induces tumor protection in colorectal cancer mouse models
Q33847891Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target
Q35374106Serum vitamin D levels of patients with oral squamous cell carcinoma (OSCC) and expression of vitamin D receptor in oral precancerous lesions and OSCC.
Q24632319Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.
Q26864979Sheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transition
Q40262786Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
Q37159360Signal transduction and transcriptional regulation during mesenchymal cell differentiation.
Q36081663Signaling circuitries controlling stem cell fate: to be or not to be.
Q37535695Signaling involved in hair follicle morphogenesis and development
Q34688315Signaling pathways in cancer and embryonic stem cells
Q92015158Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β‑catenin signaling pathway
Q36871666Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex
Q35661951Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.
Q38980557Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals
Q34604921Similar regulatory logic in Ciona intestinalis for two Wnt pathway modulators, ROR and SFRP-1/5.
Q37481066Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus.
Q37384938Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β-catenin signaling pathway after spinal cord injury
Q61961170Skeletal Stem Cell Niche of the Bone Marrow
Q37354085Skeletal metastasis: treatments, mouse models, and the Wnt signaling
Q37580273Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers
Q45999803Small Molecules Inspired by the Natural Product Withanolides as Potent Inhibitors of Wnt Signaling.
Q39376795Small molecule antibody targeting HLA class I inhibits myeloma cancer stem cells by repressing pluripotency-associated transcription factors
Q41664279Small molecule induces Wnt asymmetry in cancer
Q34817365Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic
Q24305423Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo
Q45071326Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer
Q29616163Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Q35076609Small molecules for cell reprogramming and heart repair: progress and perspective
Q38867041Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
Q36897356Small-molecule modulators of Hh and Wnt signaling pathways
Q37184855Sol narae (Sona) is a Drosophila ADAMTS involved in Wg signaling
Q51897323Some dynamic aspects of hematopoietic stem cells.
Q33947311Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium
Q39385532Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression.
Q55051527Sost Deficiency does not Alter Bone's Lacunar or Vascular Porosity in Mice.
Q64087639Sost Haploinsufficiency Provokes Peracute Lethal Cardiac Tamponade without Rescuing the Osteopenia in a Mouse Model of Excess Glucocorticoids
Q42476158Spatially defined Dsh–Lgl interaction contributes to directional tissue morphogenesis
Q37034716Stabilization of beta-catenin induces pancreas tumor formation
Q36994927Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells.
Q45349682Static magnetic fields promote osteoblastic/cementoblastic differentiation in osteoblasts, cementoblasts, and periodontal ligament cells.
Q28076017Stem cell dynamics and pretumor progression in the intestinal tract
Q36837256Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells.
Q36547723Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.
Q38586627Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy
Q38084129Stem cells and cancer stem-like cells in endocrine tissues
Q35084713Stem cells and female reproduction
Q38160452Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements.
Q36943344Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective.
Q37777341Stem cells in colon cancer. A new era in cancer theory begins
Q36117797Stem cells in melanoma development
Q37633655Stem cells in the pituitary gland: A burgeoning field
Q37936212Stem cells, quiescence and rectal carcinoma: an unexplored relationship and potential therapeutic target.
Q33572252Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.
Q27675072Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6
Q24618445Structural basis of Wnt recognition by Frizzled
Q35166834Structural studies of human Naked2: a biologically active intrinsically unstructured protein
Q39875693Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells
Q41963881Structure-activity relationship studies of small-molecule inhibitors of Wnt response
Q36381984Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled
Q37694627Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing
Q33974251Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice
Q39277545Suppression of GSK3β by ERK mediates lipopolysaccharide induced cell migration in macrophage through β-catenin signaling
Q54551098Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer.
Q28298718Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1
Q37205875Suppression of colon carcinogenesis by targeting Notch signaling
Q47272524Suppression of corneal neovascularization by curcumin via inhibition of Wnt/β-catenin pathway activation
Q39998770Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model
Q38936660Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro
Q37186425Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis
Q53303425Survivin expression in colorectal carcinomas: correlations with clinicopathological parameters and survival.
Q35034585Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer?
Q39009114Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/β-catenin pathways
Q30352525Synthesis of sydnone substituted Biginelli derivatives as hyaluronidase inhibitors.
Q34061158Synthetic, non-saccharide, glycosaminoglycan mimetics selectively target colon cancer stem cells.
Q28085367Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma
Q39733618TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling
Q34125637TBX2 and TBX3: the special value for anticancer drug targets.
Q34119730TCF-3, 4 protein expression correlates with beta-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers
Q26742019TCF/LEF Transcription Factors: An Update from the Internet Resources
Q90178576TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer
Q38950688TCF7 is suppressed by the androgen receptor via microRNA-1-mediated downregulation and is involved in the development of resistance to androgen deprivation in prostate cancer
Q37030861TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3
Q28589957TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver
Q89737194TFRC promotes epithelial ovarian cancer cell proliferation and metastasis via up-regulation of AXIN2 expression
Q34819515TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells
Q48132057TGF-β1-induced CK17 enhances cancer stem cell-like properties rather than EMT in promoting cervical cancer metastasis via the ERK1/2-MZF1 signaling pathway
Q37195207TGFbeta promotes Wnt expression during cataract development
Q35941309TLR4 Activation Promotes Bone Marrow MSC Proliferation and Osteogenic Differentiation via Wnt3a and Wnt5a Signaling
Q38739472TNF-alpha and Notch signaling regulates the expression of HOXB4 and GATA3 during early T lymphopoiesis
Q91522152TNIK signaling imprints CD8+ T cell memory formation early after priming
Q39434911TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy
Q92617776TREX1 suppression imparts cancer-stem-cell-like characteristics to CD133- osteosarcoma cells through the activation of E2F4 signaling
Q52725560TROY is a promising prognostic biomarker in patients with colorectal cancer.
Q38767082Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway
Q90887447Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts
Q42081151Targeted Therapy of Breast Cancer - New Insights and Perspectives
Q24632740Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling
Q34101433Targeted therapies for adrenocortical carcinoma: IGF and beyond
Q35802983Targeted therapy against cancer stem cells
Q37619860Targeting BET bromodomain proteins in solid tumors
Q64070902Targeting HOX/PBX dimer formation as a potential therapeutic option in esophageal squamous cell carcinoma
Q37622949Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer
Q37100742Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling
Q49544368Targeting Stemness: Implications for Precision Medicine in Breast Cancer.
Q26774623Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment
Q37820099Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
Q26783590Targeting cancer stem cells by using the nanoparticles
Q37975244Targeting embryonic signaling pathways in cancer therapy
Q26766395Targeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?
Q26775961Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy
Q36478661Targeting stem cells in brain tumors
Q39400127Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics
Q50696441Targeting the Wnt pathway in zebrafish as a screening method to identify novel therapeutic compounds.
Q35778231Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.
Q34153051Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers
Q84592877Tcf proteins are deeply rooted in skin
Q28591794Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia
Q28587342Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
Q38139289Telomerase and its extracurricular activities.
Q24615809Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
Q24310084Telomerase modulates Wnt signalling by association with target gene chromatin
Q89120729Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
Q36285737Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria
Q37846533Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
Q38983964Temporal perturbation of the Wnt signaling pathway in the control of cell reprogramming is modulated by TCF1.
Q90115372The (pro)renin receptor: a novel biomarker and potential therapeutic target for various cancers
Q40309718The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes
Q39071403The Cellular Origin and Evolution of Breast Cancer
Q36514299The Current and Future Therapies for Human Osteosarcoma
Q24310085The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin
Q37134198The Emerging Picture of Human Breast Cancer as a Stem Cell-based Disease.
Q64286848The FZD7-TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma
Q37005651The FoxO transcription factors and metabolic regulation
Q35849783The Functional SNPs in the 5' Regulatory Region of the Porcine PPARD Gene Have Significant Association with Fat Deposition Traits
Q55483353The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer.
Q77049440The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling
Q33855576The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells
Q21145899The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling
Q35464851The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation
Q39417818The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma
Q90394601The Role of Polycomb Repressive Complex in Malignant Peripheral Nerve Sheath Tumor
Q38202820The Role of Tricho-Rhino-Phalangeal Syndrome (TRPS) 1 in Apoptosis during Embryonic Development and Tumor Progression
Q49804881The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor.
Q49593660The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets.
Q41510704The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.
Q26749450The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells
Q37543996The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells
Q34577694The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells.
Q28507014The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development
Q50949116The Wnt inhibitor secreted Frizzled-Related Protein 1 (sFRP1) promotes human Th17 differentiation.
Q35085317The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence
Q39432100The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
Q34688333The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion.
Q28589724The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis
Q38698293The Wnt/β-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation
Q34670501The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target.
Q37928570The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer
Q37215096The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer
Q33316388The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens
Q35849968The anti-obesity effects of a tuna peptide on 3T3-L1 adipocytes are mediated by the inhibition of the expression of lipogenic and adipogenic genes and by the activation of the Wnt/β-catenin signaling pathway
Q28274002The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation
Q33412512The atonal proneural transcription factor links differentiation and tumor formation in Drosophila
Q34284208The balance between two isoforms of LEF-1 regulates colon carcinoma growth
Q42006583The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner
Q33987011The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development
Q38006769The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells
Q37351482The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.
Q39924925The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression
Q37954461The biology of head and neck cancer stem cells
Q37013896The c-myc promoter: still MysterY and challenge
Q36854372The cancer stem cell paradigm: a new understanding of tumor development and treatment
Q36293300The canonical Wg signaling modulates Bsk-mediated cell death in Drosophila
Q36916471The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis
Q36535617The canonical Wnt signalling pathway and its APC partner in colon cancer development
Q38175297The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells.
Q54354272The changes of stemness biomarkers expression in human adipose-derived stem cells during long-term manipulation.
Q38197098The colon cancer stem cell microenvironment holds keys to future cancer therapy
Q36977621The complex pathways of Wnt 5a in cancer progression
Q38059785The complex world of WNT receptor signalling
Q37977006The contribution of bone to whole-organism physiology
Q36672152The contribution of epidermal stem cells to skin cancer
Q39090367The cross-regulation between SOX15 and Wnt signaling pathway
Q35566484The crossroads between cancer stem cells and aging.
Q24623318The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice
Q35394164The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes
Q36842360The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
Q37551261The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells
Q34310378The epigenetics of epithelial-mesenchymal plasticity in cancer
Q36515479The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
Q37285682The first propeller domain of LRP6 regulates sensitivity to DKK1.
Q37035383The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology
Q38608775The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma
Q38569328The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell
Q38045265The hitchhikers guide to cancer stem cell theory: markers, pathways and therapy.
Q36797661The implications of small stem cell niche sizes and the distribution of fitness effects of new mutations in aging and tumorigenesis
Q39372971The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
Q26751224The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets
Q36545318The metastasis suppressor, NDRG1, inhibits "stemness" of colorectal cancer via down-regulation of nuclear β-catenin and CD44.
Q38644651The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
Q37189432The molecular genetics of medulloblastoma: an assessment of new therapeutic targets
Q36231787The molecular repertoire of the 'almighty' stem cell
Q40560744The next new target in leukemia: The embryonic stem cell gene SALL4.
Q26849444The niche under siege: novel targets for metastasis therapy
Q59098615The not-so-odd couple
Q37317534The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance
Q34489510The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas
Q35348787The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling
Q59548470The pathogenic role of Notch activation in podocytes
Q36790737The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues.
Q38202202The potential of targeting Wnt/β-catenin in colon cancer
Q24319976The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling
Q38304775The recovery process of mice tracheal epithelium injured by 5-FU and its microarray analysis
Q33630327The repressive effect of miR-148a on Wnt/β-catenin signaling involved in Glabridin-induced anti-angiogenesis in human breast cancer cells
Q39028181The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer
Q37365676The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells
Q37610703The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells.
Q44669927The role of Pygopus 2 in rat glioma cell growth
Q28468370The role of T‑box genes in the tumorigenesis and progression of cancer (Review)
Q38216639The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance
Q37029666The role of matrix metalloproteinases in stromal/epithelial interactions in the gut.
Q24613730The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer
Q37858470The role of p63 in cancer, stem cells and cancer stem cells.
Q36292780The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt
Q37139152The role of thyroid hormone signaling in the prevention of digestive system cancers
Q51945868The roles of Wnt antagonists Dkk1 and sFRP4 during adipogenesis of human adipose tissue-derived mesenchymal stem cells.
Q34018084The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity
Q21560986The spatial distribution of LGR5+ cells correlates with gastric cancer progression
Q42803494The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled
Q37810502The tissue-specific stem cell as a target for chemoprevention
Q36072943The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer
Q53055743The tumor suppressor APC differentially regulates multiple β-catenins through the function of axin and CKIα during C. elegans asymmetric stem cell divisions.
Q39097606The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3β activity in cell growth of esophageal carcinoma
Q38210024The ubiquitin-conjugating system: multiple roles in viral replication and infection
Q36596696The vitamin D receptor as a therapeutic target
Q37138638The vitamin D receptor in cancer
Q38068918The way Wnt works: components and mechanism.
Q37615918Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma
Q36833275Therapeutic targeting of the p53 pathway in cancer stem cells.
Q38416280Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques
Q24295448Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity
Q34674947Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche
Q36099445Threonine 393 of beta-catenin regulates interaction with Axin
Q36771868Tie-2 regulates the stemness and metastatic properties of prostate cancer cells.
Q27010086Tissue engineering: from research to dental clinics
Q52365303Tissue transglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche.
Q36296335Tissue-specific tumorigenesis: context matters
Q37282291Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer
Q24314891Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains
Q89810253Tracing tumorigenesis in a solid tumor model at single-cell resolution
Q90352947Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma
Q41697916Transcription factor TCF4 maintains the properties of human corneal epithelial stem cells
Q37982837Transcription factor network regulating CD(+)CD8(+) thymocyte survival
Q60922665Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells
Q36570605Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer
Q34875987Transcriptomic portrait of human Mesenchymal Stromal/Stem Cells isolated from bone marrow and placenta
Q38904274Transgenic expression of a canonical Wnt inhibitor, kallistatin, is associated with decreased circulating CD19+ B lymphocytes in the peripheral blood
Q54360289Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype.
Q34205345Treatment of glioblastoma multiforme using a combination of small interfering RNA targeting epidermal growth factor receptor and β-catenin.
Q36616513Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth
Q33823652Tumor inhibition by sodium selenite is associated with activation of c-Jun NH2-terminal kinase 1 and suppression of beta-catenin signaling
Q39425138Tumor microenvironment and noncoding RNAs as co-drivers of epithelial-mesenchymal transition and cancer metastasis.
Q42502782Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling
Q35914643Tumor suppressor function of RUNX3 in breast cancer
Q49494144Tumor-infiltrating lymphocytes are associated with β-catenin overexpression in breast cancer.
Q37774865Tumor-initiating and -propagating cells: cells that we would like to identify and control
Q37606286Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
Q36324925Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity
Q40084609Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis
Q35193091Two Natural ent-kauranoids as Novel Wnt Signaling Inhibitors
Q39830811Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells
Q34978471Type I interferons link viral infection to enhanced epithelial turnover and repair.
Q93131971USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation
Q36601000Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
Q37520106Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection
Q35079346Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing
Q36907405Understanding and targeting cancer stem cells: therapeutic implications and challenges
Q47069994Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo
Q53089167Unravelling cancer stem cell potential.
Q36558594Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions
Q36580511Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin
Q92254375Upregulation of non-canonical Wnt ligands and oxidative glucose metabolism in NASH induced by methionine-choline deficient diet
Q38222159Using proteomics to unravel the mysterious steps of the HBV-life-cycle
Q47732691Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response
Q36889627Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers
Q35096327Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer
Q35879070Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases
Q30179397VentX trans-activates p53 and p16ink4a to regulate cellular senescence
Q46250945Verrucarin J inhibits ovarian cancer and targets cancer stem cells
Q33999763Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer.
Q38899864WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1.
Q34591481WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors
Q84914069WITHDRAWN: Molecular Characteristics of Bone Marrow Mesenchymal Stem Cells: An Appealing Source for Regenerative Medicine
Q38456692WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis
Q92422653WNT Signaling in Disease
Q39049231WNT Signaling in Lung Aging and Disease.
Q41074649WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
Q33917543WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling
Q37277156WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth
Q38660744WNT signaling in glioblastoma and therapeutic opportunities
Q37212748WNT signalling in the immune system: WNT is spreading its wings
Q42498835WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production
Q37798975Wg signaling in Drosophila heart development as a pioneering model
Q26825780What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway
Q47801457What do polymorphisms tell us about the mechanisms of COPD?
Q35195877Whole-exome sequencing of endometriosis identifies frequent alterations in genes involved in cell adhesion and chromatin-remodeling complexes
Q37866140Wilms tumor--a renal stem cell malignancy?
Q42200637Wingless signaling induces widespread chromatin remodeling of target loci.
Q41771195Wingless/Wnt signal transduction requires distinct initiation and amplification steps that both depend on Arrow/LRP.
Q28543359Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells
Q53568356Wls promotes the proliferation of breast cancer cells via Wnt signaling.
Q92315665Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children
Q64229171Wnt Signaling Pathway Linked to Intestinal Regeneration via Evolutionary Patterns and Gene Expression in the Sea Cucumber
Q90382654Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis
Q39306017Wnt Signaling in Normal and Malignant Stem Cells
Q90721202Wnt Signaling in Ovarian Cancer Stemness, EMT, and Therapy Resistance
Q51766147Wnt Signalling in Intestinal Stem Cells: Lessons from Mice and Flies.
Q30360502Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.
Q34232635Wnt activation is implicated in glioblastoma radioresistance
Q35192737Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.
Q33267354Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer
Q92177011Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells
Q47901236Wnt and frizzled expression during regeneration of internal organs in the holothurian Eupentacta fraudatrix
Q33248385Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis
Q33280730Wnt expression in the adult rat subventricular zone after stroke
Q33614955Wnt gene expression in human trabecular meshwork cells.
Q34393633Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia
Q35642680Wnt ligands regulate Tkv expression to constrain Dpp activity in the Drosophila ovarian stem cell niche
Q35101885Wnt modulates MCL1 to control cell survival in triple negative breast cancer
Q37026623Wnt modulating agents inhibit human cytomegalovirus replication
Q34976628Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
Q39298930Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line
Q34323825Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
Q50648164Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis.
Q39709638Wnt proteins promote bone regeneration
Q37305230Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells
Q36430885Wnt signal transduction and the formation of the myocardium
Q24641814Wnt signal transduction pathways
Q35132203Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans
Q37864083Wnt signaling and colon carcinogenesis: beyond APC.
Q36702732Wnt signaling and human diseases: what are the therapeutic implications?
Q34293036Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development
Q34262857Wnt signaling in cancer
Q51518956Wnt signaling in cancer.
Q33360705Wnt signaling in dendritic cells: its role in regulation of immunity and tolerance
Q34541487Wnt signaling in estrogen-induced lactotroph proliferation.
Q91643281Wnt signaling in liver disease: emerging trends from a bibliometric perspective
Q38219832Wnt signaling in osteosarcoma
Q33274270Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures
Q25257722Wnt signaling induces epithelial differentiation during cutaneous wound healing
Q37198555Wnt signaling inhibits CTL memory programming
Q53221750Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells.
Q34892024Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation
Q37376243Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord.
Q42546329Wnt signaling mediates pathological vascular growth in proliferative retinopathy
Q33850074Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment
Q48274790Wnt signaling pathway regulates differentiation of chicken embryonic stem cells into spermatogonial stem cells via Wnt5a.
Q34578573Wnt signaling promotes regeneration in the retina of adult mammals.
Q28741624Wnt signaling promotes reprogramming of somatic cells to pluripotency
Q35138570Wnt signaling regulates hepatic metabolism
Q24337717Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
Q24646716Wnt signaling, lgr5, and stem cells in the intestine and skin
Q42566173Wnt signaling, stem cells, and cancer of the gastrointestinal tract
Q37539422Wnt signalling and cancer stem cells.
Q22000774Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours
Q38055435Wnt signalling in kidney diseases: dual roles in renal injury and repair
Q25256712Wnt signalling in lung development and diseases
Q42321100Wnt signalling is a bi-directional vulnerability of cancer cells
Q90192464Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells
Q38874181Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment.
Q38221361Wnt-Notch signalling crosstalk in development and disease.
Q37362237Wnt-induced proteolytic targeting
Q30581875Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer
Q37287025Wnt-signaling and senescence: A tug of war in early neoplasia?
Q28077396Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches
Q34006063Wnt/beta-catenin inhibits dental pulp stem cell differentiation.
Q21195874Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma
Q40020289Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis
Q46160238Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure
Q34959673Wnt/catenin signaling in adult stem cell physiology and disease
Q35640118Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer
Q64119442Wnt/β-Catenin Pathway Is Involved in Cadmium-Induced Inhibition of Osteoblast Differentiation of Bone Marrow Mesenchymal Stem Cells
Q57478274Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs
Q50435067Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor.
Q37132716Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.
Q26823272Wnt/β-catenin signaling and disease
Q38609596Wnt/β-catenin signaling in bone marrow niche.
Q37878387Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming
Q46344011Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production
Q33945336Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway
Q42495424Wnt/β-catenin signaling is critical for dedifferentiation of aged epidermal cells in vivo and in vitro
Q46241724Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway
Q39278906Wnt/β-catenin signaling pathway upregulates c-Myc expression to promote cell proliferation of P19 teratocarcinoma cells
Q38807957Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.
Q24338743Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells
Q35887244Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
Q34637692Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells
Q34765411Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells.
Q39095813Wnt16 is involved in intramembranous ossification and suppresses osteoblast differentiation through the Wnt/β-catenin pathway
Q42156387Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain
Q90136497Wnt3a protein overexpression predicts worse overall survival in laryngeal squamous cell carcinoma
Q40062995Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells
Q53292749Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins.
Q33366930Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation
Q36058721Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.
Q33604792Wnt5a Signaling in Normal and Cancer Stem Cells
Q36002416Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation
Q28590609Wnt5a inhibits the proliferation and melanogenesis of melanocytes
Q41890684Wnt5a knock-out mouse as a new model of anorectal malformation
Q44956652Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice
Q39030481Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial-mesenchymal transition
Q35256323Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence
Q42706277Wnt5a/β-catenin signaling drives calcium-induced differentiation of human primary keratinocytes
Q47158860Wnt6 influences the viability of mouse embryonic palatal mesenchymal cells via the β-catenin pathway
Q24329073Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
Q39306487Wnts Are Expressed in the Ependymal Region of the Adult Spinal Cord
Q36672661Wnts as ligands: processing, secretion and reception
Q38172119Wnts in adult brain: from synaptic plasticity to cognitive deficiencies
Q38833977Wogonoside inhibits angiogenesis in breast cancer via suppressing Wnt/β-catenin pathway
Q38219611Wound infections and healing: are they contributing factors for carcinogenesis?
Q33526741Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction.
Q37985651Xenopus: an ideal system for chemical genetics.
Q24292724Yes and PI3K bind CD95 to signal invasion of glioblastoma
Q89634242Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation
Q53283058[Non-serrated precursor lesions of colorectal tumours].
Q54587716[Signaling and metabolic predispositions linked to the colorectal cancer].
Q53280241[The utilization and limitation of CD133 epitopes in lung cancer stem cells research].
Q33844856beta-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia
Q28276987beta-catenin destruction complex: insights and questions from a structural perspective
Q36645589dFoxO promotes Wingless signaling in Drosophila
Q92998611dTcf/Pangolin suppresses growth and tumor formation in Drosophila
Q57116044is a novel oncogenic prognostic biomarker in human glioblastoma
Q34129574mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Q34529305miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway
Q49265258miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a.
Q34299316miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling
Q53553780miR-29a modulates tumor necrosis factor-α-induced osteogenic inhibition by targeting Wnt antagonists.
Q38360083miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway
Q61802785miR-600 inhibits lung cancer via downregulating the expression of METTL3
Q38742731miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7.
Q35793683miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/β-catenin signalling pathway
Q42034071p53 in the CNS: Perspectives on Development, Stem Cells, and Cancer
Q34285194sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair
Q34283057ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling
Q36351212α-Catulin marks the invasion front of squamous cell carcinoma and is important for tumor cell metastasis
Q34028517α-catenin. A tumor suppressor beyond adherens junctions
Q47110007β-Catenin Accumulation Is Associated With Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-Renewal
Q41644202β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells.
Q37991708β-Catenin Signalling in Glioblastoma Multiforme and Glioma-Initiating Cells
Q38796204β-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma
Q35058248β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells
Q87418047β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer
Q34961818β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors
Q39454255β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway
Q54117203β-arrestin2 Affects Cardiac Progenitor Cell Survival through Cell Mobility and Tube Formation in Severe Hypoxia.
Q39345531β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer
Q34353437β-catenin contributes to lung tumor development induced by EGFR mutations
Q34730103β-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells
Q42315542β-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients
Q37634132β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis
Q52633614β-catenin is required in odontoblasts for tooth root formation.
Q34265458β-catenin knockdown enhances the effects of fluorouracil in the breast cancer cell line MDA-MB-468.
Q42976183β-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network
Q35096982β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells
Q39016072β-catenin regulates NF-κB activity via TNFRSF19 in colorectal cancer cells
Q36706395β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases
Q26821842β-catenin/TCF-1 pathway in T cell development and differentiation
Q35012043β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma
Q35083197βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin

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