scholarly article | Q13442814 |
retracted paper | Q45182324 |
P50 | author | Paola Briata | Q30089832 |
Roberto Gherzi | Q91623926 | ||
Roberto Gherzi | Q30089833 | ||
Marco Ponassi | Q30089835 | ||
Tina Ruggiero | Q30089837 | ||
P2093 | author name string | Jens S Andersen | |
Ching-Yi Chen | |||
Giorgio Corte | |||
Christoph Moroni | |||
Michele Trabucchi | |||
Khalid S Khabar | |||
P2860 | cites work | AU binding proteins recruit the exosome to degrade ARE-containing mRNAs | Q24291926 |
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding | Q24302401 | ||
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay | Q24316111 | ||
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay | Q24548948 | ||
The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B | Q24558903 | ||
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway | Q24653458 | ||
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. | Q24816506 | ||
ARED 3.0: the large and diverse AU-rich transcriptome. | Q25257878 | ||
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1 | Q28118675 | ||
Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth | Q28187862 | ||
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development | Q28216579 | ||
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery | Q28264688 | ||
Messenger RNA turnover in eukaryotes: pathways and enzymes | Q28298137 | ||
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts | Q28594660 | ||
Role of translocation in the activation and function of protein kinase B | Q28609902 | ||
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) | Q28640016 | ||
The structural basis for 14-3-3:phosphopeptide binding specificity | Q29547190 | ||
Wnt signaling: a common theme in animal development | Q29547527 | ||
Wnt signalling in stem cells and cancer | Q29547862 | ||
HuR and mRNA stability | Q29615185 | ||
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor. | Q54395492 | ||
Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation | Q73787446 | ||
14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking | Q42125847 | ||
Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation | Q42809920 | ||
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway | Q45234630 | ||
Molecular determinants of Akt-induced keratinocyte transformation | Q46772716 | ||
Activation of the Wnt signaling pathway: a molecular mechanism for lithium action | Q48958687 | ||
A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis. | Q52831298 | ||
Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display | Q30776583 | ||
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. | Q34330731 | ||
Protein kinase B/Akt at a glance | Q34474692 | ||
p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts | Q34811464 | ||
Role of Akt/protein kinase B in metabolism. | Q34997136 | ||
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation | Q35193952 | ||
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons | Q35563894 | ||
Advances in protein kinase B signalling: AKTion on multiple fronts | Q35766370 | ||
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. | Q35829153 | ||
Bringing the role of mRNA decay in the control of gene expression into focus | Q35885699 | ||
Recent advances in the protein kinase B signaling pathway | Q36076055 | ||
Control of mRNA stability in eukaryotes | Q36295604 | ||
MAPKAP kinases - MKs - two's company, three's a crowd | Q36371939 | ||
Yin-yang 1 activates the c-myc promoter | Q36827465 | ||
Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt. | Q37593591 | ||
Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. | Q38319485 | ||
Role of the RNA-binding protein HuR in colon carcinogenesis | Q38349167 | ||
Signal transduction through beta-catenin and specification of cell fate during embryogenesis | Q38530598 | ||
Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase | Q39460786 | ||
Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling | Q40279493 | ||
AU-rich elements and alternative splicing in the beta-catenin 3'UTR can influence the human beta-catenin mRNA stability | Q40280621 | ||
Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors | Q40486178 | ||
The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs | Q40613619 | ||
Akt participation in the Wnt signaling pathway through Dishevelled | Q40817549 | ||
Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling | Q40866028 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | RNA-binding proteins | Q3928341 |
P304 | page(s) | e5 | |
P577 | publication date | 2006-12-01 | |
P1433 | published in | PLOS Biology | Q1771695 |
P1476 | title | The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling | |
P478 | volume | 5 |
Q35894762 | 5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats |
Q37014717 | A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells |
Q37749080 | A review of methods to monitor the modulation of mRNA stability: a novel approach to drug discovery and therapeutic intervention |
Q40675814 | A versatile ribosomal protein promoter-based reporter system for selective assessment of RNA stability and post-transcriptional control |
Q28588044 | AS160 modulates aldosterone-stimulated epithelial sodium channel forward trafficking |
Q43127498 | AU-rich elements regulate Drosophila gene expression. |
Q35902641 | Above genetics: lessons from cerebral development in autism |
Q53190419 | Activation of mTORC1 in B Lymphocytes Promotes Osteoclast Formation via Regulation of β-Catenin and RANKL/OPG. |
Q45328178 | Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics |
Q28583125 | Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain |
Q39932300 | Akt phosphorylation of La regulates specific mRNA translation in glial progenitors |
Q39761766 | Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation |
Q28510351 | Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA |
Q37958686 | BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype |
Q30992379 | BRCA1 modulates the expression of hnRNPA2B1 and KHSRP. |
Q39239904 | Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation |
Q46183168 | CD28 signaling in T regulatory precursors requires p56lck and rafts integrity to stabilize the Foxp3 message |
Q34343685 | Complete deletion of Apc results in severe polyposis in mice |
Q35816361 | Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells |
Q34984530 | DEAD box protein DDX1 regulates cytoplasmic localization of KSRP |
Q33817646 | Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation |
Q43251969 | Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts |
Q54648889 | Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin. |
Q33763825 | Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA. |
Q37739651 | Diversity in post-transcriptional control of neutrophil chemoattractant cytokine gene expression |
Q38572889 | Does miRNA-155 Promote Cyclooxygenase-2 Expression in Cancer? |
Q39100118 | Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat. |
Q36751314 | Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins. |
Q42413090 | FasL expression in activated T lymphocytes involves HuR-mediated stabilization |
Q30480964 | Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets |
Q38062295 | Functional and molecular insights into KSRP function in mRNA decay |
Q34675049 | Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells |
Q34601079 | H19 long noncoding RNA controls the mRNA decay promoting function of KSRP. |
Q42421191 | HnRNP A1 tethers KSRP to an exon splicing silencer that inhibits an erythroid-specific splicing event in PU.1-induced erythroleukemia |
Q38342449 | IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA. |
Q33694001 | IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence |
Q28222344 | Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling |
Q38797458 | Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA. |
Q55052910 | Identification of autoantigens in pediatric opsoclonus-myoclonus syndrome. |
Q33399670 | Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements |
Q47433840 | Inflammation-regulated mRNA stability and the progression of vascular inflammatory diseases. |
Q37560020 | Inflammation: cytokines and RNA-based regulation |
Q41458214 | Integrative analysis of cancer-related signaling pathways |
Q39941914 | Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules. |
Q38675443 | Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism |
Q30496858 | Intracellular localization and interaction of mRNA binding proteins as detected by FRET |
Q36144919 | KH domains with impaired nucleic acid binding as a tool for functional analysis |
Q42697394 | KH-type splicing regulatory protein is a new component of chromatoid body |
Q42704822 | KHSRP participates in manganese-induced neurotoxicity in rat striatum and PC12 cells |
Q89496313 | KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer |
Q84557073 | KSRP Promotes the Maturation of a Group of miRNA Precuresors |
Q50295847 | KSRP binds AU-rich element in 3' UTR of mRNA |
Q38213168 | KSRP controls pleiotropic cellular functions |
Q35014217 | KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression. |
Q46061449 | KSRP promotes the maturation of a group of miRNA precursors. |
Q39332374 | Knockdown of hMex-3A by small RNA interference suppresses cell proliferation and migration in human gastric cancer cells |
Q34979721 | LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages |
Q21563369 | Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP |
Q39074804 | Lysophosphatidic acid activates β-catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19-7 cells |
Q28564755 | Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs |
Q26823168 | Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions |
Q39934586 | NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis. |
Q37940393 | Networks controlling mRNA decay in the immune system. |
Q36802838 | Nuclear HuR accumulation through phosphorylation by Cdk1 |
Q37103971 | Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma |
Q46843731 | Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis |
Q52695010 | P38 activation induces the dissociation of tristetraprolin from Argonaute 2 to increase ARE-mRNA stabilization. |
Q39480671 | PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis |
Q39096070 | Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated BST-2/tetherin regulation |
Q36960953 | Phosphorylated HuR shuttles in cycles |
Q34485096 | Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment |
Q27653675 | Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding |
Q51306606 | Post-Translational Modifications and RNA-Binding Proteins. |
Q34065213 | Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements |
Q37113415 | Post-transcriptional control of cytokine production |
Q90456271 | Post-transcriptional mechanisms regulating parathyroid hormone gene expression in secondary hyperparathyroidism |
Q42103783 | Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection |
Q37051346 | Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence |
Q35667581 | Posttranscriptional regulation of miRNAs in the DNA damage response |
Q34281170 | PreImplantation factor promotes neuroprotection by targeting microRNA let-7 |
Q50295849 | Protein Kinase B (AKT) phosphorylates KSRP |
Q38216092 | Protein folding dynamics in the cell |
Q39485236 | Proteomic analysis of 1α,25-dihydroxyvitamin D3 action on human colon cancer cells reveals a link to splicing regulation. |
Q87687655 | RNA-binding protein-mediated post-transcriptional controls of gene expression: integration of molecular mechanisms at the 3' end of mRNAs? |
Q41998210 | RNA-binding proteins as a point of convergence of the PI3K and p38 MAPK pathways |
Q36776927 | Rapid transit in the immune cells: the role of mRNA turnover regulation. |
Q36983557 | Regulated unfolding of proteins in signaling |
Q53083286 | Regulation of ARE-mRNA Stability by Cellular Signaling: Implications for Human Cancer. |
Q27023916 | Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1 |
Q36647195 | Reprogramming of the microRNA transcriptome mediates resistance to rapamycin |
Q43173072 | Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling |
Q26860434 | Role of KSRP in control of type I interferon and cytokine expression |
Q36870110 | SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis |
Q35142761 | Signaling-mediated regulation of MicroRNA processing |
Q45093146 | Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury |
Q35213072 | Structural basis for regulation of RNA-binding proteins by phosphorylation |
Q33704980 | Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR. |
Q35043572 | The ATM kinase induces microRNA biogenesis in the DNA damage response. |
Q28118107 | The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2 |
Q37401219 | The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs |
Q34143021 | The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer. |
Q34024670 | The exozyme model: a continuum of functionally distinct complexes. |
Q52887347 | The far-upstream element-binding protein 2 is correlated with proliferation and doxorubicin resistance in human breast cancer cell lines. |
Q39434281 | The interplay between transcription and mRNA degradation in Saccharomyces cerevisiae |
Q28573676 | The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels |
Q39796772 | The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism. |
Q35095098 | The ribonome: a dominant force in co-ordinating gene expression |
Q37936370 | The role of KSRP in mRNA decay and microRNA precursor maturation |
Q37492933 | The role of mammalian ribonucleases (RNases) in cancer |
Q27644470 | The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation |
Q39144733 | Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of the BCR, TLRs and FcγR. |
Q37940420 | Turnover of AU-rich-containing mRNAs during stress: a matter of survival. |
Q34654416 | Understanding the somitogenesis clock: what's missing? |
Q38076192 | Wnt/β-catenin signalling: from plasma membrane to nucleus |
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Q39653613 | mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling |
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