The interplay between transcription and mRNA degradation in Saccharomyces cerevisiae

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The interplay between transcription and mRNA degradation in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15698/MIC2017.07.580
P932PMC publication ID5507684
P698PubMed publication ID28706937

P2093author name stringBiswadip Das
Debasish Sarkar
Subhadeep Das
P2860cites workPhosphorylation and inactivation of Tob contributes to the progression of papillary carcinoma of the thyroidQ81520552
Transcription and mRNA stability: parental guidance suggestedQ83129986
Promoter elements regulate cytoplasmic mRNA decayQ83129997
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signalingQ21145899
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeastQ21146425
Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinasesQ22010949
The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activationQ22011002
Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epitheliumQ24290276
Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathwayQ24290687
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20Q24291673
AU binding proteins recruit the exosome to degrade ARE-containing mRNAsQ24291926
CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylaseQ24292432
The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatasesQ24305331
The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferationQ24314993
A nuclear cap binding protein complex involved in pre-mRNA splicingQ24318104
The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivatorsQ24323052
Interaction of BTG1 and p53-regulated BTG2 gene products with mCaf1, the murine homolog of a component of the yeast CCR4 transcriptional regulatory complexQ24336221
ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous systemQ24336775
The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1Q24337174
Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeastQ24535685
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structuresQ24543188
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expressionQ24548310
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayQ24548948
Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNAQ24551147
The roles of TTP and BRF proteins in regulated mRNA decayQ24633013
Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridizationQ24657378
Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylasesQ24675982
Cytoplasmic foci are sites of mRNA decay in human cellsQ24677437
Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationQ24681334
Ccr4-Not complex: the control freak of eukaryotic cellsQ26823940
Mechanisms of deadenylation-dependent decayQ26829435
Threading the barrel of the RNA exosomeQ26851853
Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localizationQ27301294
Crystal structure of Dcp1p and its functional implications in mRNA decappingQ27643076
Structural Basis of Dcp2 Recognition and Activation by Dcp1Q27649872
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 bindingQ27653675
Exploring the metabolic and genetic control of gene expression on a genomic scaleQ27860705
Lithium toxicity in yeast is due to the inhibition of RNA processing enzymesQ33887852
Role of the essential yeast protein PSU1 in p6anscriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptorsQ33890783
Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decayQ33934924
mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.Q33966181
mRNA export: an assembly line from genes to nuclear poresQ33978326
Coupled evolution of transcription and mRNA degradationQ33979465
Formation of export-competent mRNP: escaping nuclear destructionQ33987252
RNA turnover: unexpected consequences of being tailedQ33989462
Transcriptome kinetics is governed by a genome-wide coupling of mRNA production and degradation: a role for RNA Pol IIQ34023047
On the importance of being co-transcriptionalQ34150533
Assembly and transport of a premessenger RNP particleQ34287429
Nuclear export of RNA.Q34364012
RNA decay modulates gene expression and controls its fidelityQ34364183
Analysis of recombinant yeast decapping enzymeQ34364990
Coactivation of nuclear receptors and myogenic factors induces the major BTG1 influence on muscle differentiationQ34388708
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant roleQ34451316
Accumulation of unstable promoter-associated transcripts upon loss of the nuclear exosome subunit Rrp6p in Saccharomyces cerevisiaeQ34480038
Genetic interactions between Nhp6 and Gcn5 with Mot1 and the Ccr4-Not complex that regulate binding of TATA-binding protein in Saccharomyces cerevisiaeQ34587825
Coupling mRNA synthesis and decayQ34592670
Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAsQ34608970
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophagesQ34979721
Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cellsQ35044194
Early formation of mRNP: license for export or quality control?Q35137961
Coupling transcription, splicing and mRNA exportQ35145838
The interplay of nuclear mRNP assembly, mRNA surveillance and exportQ35147368
Nucleocytoplasmic transport: integrating mRNA production and turnover with export through the nuclear poreQ35732522
The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?Q35805081
Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover.Q35843568
Cell cycle-dependent transcription in yeast: promoters, transcription factors, and transcriptomesQ36101736
Cotranscriptional mRNP assembly: from the DNA to the nuclear poreQ36131482
TREX, SR proteins and export of mRNA.Q36131499
Process or perish: quality control in mRNA biogenesisQ36149583
Dynamic nuclear pore complexes: life on the edge.Q36508009
The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeastQ27929773
Mapping pathways and phenotypes by systematic gene overexpressionQ27930674
Gene expression is circular: factors for mRNA degradation also foster mRNA synthesisQ27930898
PUF proteins bind Pop2p to regulate messenger RNAsQ27930941
Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.Q27930971
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeastQ27931030
Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms.Q27931642
Regulation of Snf1 kinase. Activation requires phosphorylation of threonine 210 by an upstream kinase as well as a distinct step mediated by the Snf4 subunitQ27931918
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymeraseQ27932117
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.Q27932152
The multifunctional Ccr4-Not complex directly promotes transcription elongationQ27933267
The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAsQ27933345
Nucleocytoplasmic shuttling of the Rpb4p and Rpb7p subunits of Saccharomyces cerevisiae RNA polymerase II by two pathwaysQ27933627
Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeastQ27934046
The Rpb4 subunit of RNA polymerase II contributes to cotranscriptional recruitment of 3' processing factorsQ27934138
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complexQ27934144
The yeast POP2 gene encodes a nuclease involved in mRNA deadenylationQ27934881
RNA polymerase II subunits link transcription and mRNA decay to translation.Q27934915
NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilizationQ27935983
Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levelsQ27935989
Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAsQ27936762
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiaeQ27937531
The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiaeQ27937565
Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiaeQ27937817
The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms.Q27937902
The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzymeQ27937948
RNA polymerase II subunit composition, stoichiometry, and phosphorylationQ27938734
The cell-cycle-regulated budding yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle controlQ27938888
Targeting of aberrant mRNAs to cytoplasmic processing bodiesQ27939158
Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II.Q27939580
Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stressQ27939602
Dissociable Rpb4-Rpb7 subassembly of rna polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation.Q27939905
Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator proteinQ27939923
A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAsQ36531857
The control of elongation by the yeast Ccr4-not complexQ36532642
Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiaeQ36563128
The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promotersQ36564000
Snf1-Dependent Transcription Confers Glucose-Induced Decay upon the mRNA ProductQ36574869
Determination of mRNA fate by different RNA polymerase II promotersQ36632883
Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae.Q36670947
Degradation of mRNAs that lack a stop codon: a decade of nonstop progressQ36802258
mRNA stability and cancer: an emerging link?Q36960486
SNF1/AMPK pathways in yeastQ36992466
RNA quality control in eukaryotesQ37005637
CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafterQ37013917
XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Q37092102
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleusQ37144184
Quality control of mRNP in the nucleusQ37194592
NMD: multitasking between mRNA surveillance and modulation of gene expressionQ37325822
Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAsQ37338867
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAsQ37401219
BTG/TOB factors impact deadenylasesQ37455743
The fate of the messenger is pre-determined: a new model for regulation of gene expressionQ37477468
"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactionsQ37620941
Linking gene regulation to mRNA production and export.Q37827981
The eukaryotic RNA exosome: same scaffold but variable catalytic subunitsQ37834909
RNA in piecesQ37899350
The role of KSRP in mRNA decay and microRNA precursor maturationQ37936370
The Ccr4--not complexQ37949473
RNA degradation in Saccharomyces cerevisaeQ38025564
Transcription-associated quality control of mRNP.Q38043828
Structural and functional control of the eukaryotic mRNA decapping machinery.Q38071446
RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes.Q38075754
RNA decay machines: the exosomeQ38077004
Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression.Q38087205
How cells get the message: dynamic assembly and function of mRNA-protein complexesQ38088112
Mechanisms of mRNA exportQ38210592
Multiple pathways are co-regulated by the protein kinase Snf1 and the transcription factors Adr1 and Cat8.Q38355889
Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomesQ38591386
Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBFQ27940237
Robust heat shock induces eIF2alpha-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae.Q27940310
Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancerQ28187810
In search of a function for the TIS21/PC3/BTG1/TOB familyQ28190978
Tob is a negative regulator of activation that is expressed in anergic and quiescent T cellsQ28203889
Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complexQ28203973
The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?Q28206741
Exporting RNA from the nucleus to the cytoplasmQ28245155
RNA-quality control by the exosomeQ28251052
The mammalian anti-proliferative BTG/Tob protein familyQ28258172
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machineryQ28264688
Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tailQ28297786
Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycleQ28305726
Widespread bidirectional promoters are the major source of cryptic transcripts in yeastQ28307664
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcriptsQ28594660
Integrating mRNA processing with transcriptionQ28610124
An extensive network of coupling among gene expression machinesQ29547273
Bidirectional promoters generate pervasive transcription in yeastQ29614766
Progression through the RNA polymerase II CTD cycleQ29614782
Pre-mRNA processing reaches back to transcription and ahead to translationQ29615045
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granulesQ29615265
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decayQ29616054
RNA regulons: coordination of post-transcriptional eventsQ29618919
An essential component of the decapping enzyme required for normal rates of mRNA turnoverQ29620356
RNA-destabilizing factor tristetraprolin negatively regulates NF-kappaB signalingQ30434431
Towards systematic discovery of signaling networks in budding yeast filamentous growth stress response using interventional phosphorylation dataQ30653362
Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiaeQ30845065
Cell-cycle checkpoints that ensure coordination between nuclear and cytoplasmic events in Saccharomyces cerevisiaeQ33179758
Links between mRNA splicing, mRNA quality control, and intellectual disabilityQ33364292
Heat shock response in yeast involves changes in both transcription rates and mRNA stabilitiesQ33833790
DBF2, a cell cycle-regulated protein kinase, is physically and functionally associated with the CCR4 transcriptional regulatory complexQ33887373
Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decappingQ38614772
Viral Nucleases Induce an mRNA Degradation-Transcription Feedback Loop in Mammalian CellsQ38849238
Loss of B-cell translocation gene-2 in estrogen receptor-positive breast carcinoma is associated with tumor grade and overexpression of cyclin d1 proteinQ40254036
Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing.Q40342109
Transcriptional priming of cytoplasmic post-transcriptional regulationQ40645997
Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiaeQ40655338
Widespread promoter-mediated coordination of transcription and mRNA degradationQ40666069
Formation of cytoplasmic heat shock granules in tomato cell cultures and leavesQ40680336
Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processesQ41307665
Lsm1 promotes genomic stability by controlling histone mRNA decayQ41770464
Specific and global regulation of mRNA stability during osmotic stress in Saccharomyces cerevisiae.Q42050768
Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradationQ42236163
A common strategy for host RNA degradation by divergent virusesQ42270342
Cell-cycle regulation of yeast histone mRNA.Q42467119
Tristetraprolin impairs NF-kappaB/p65 nuclear translocationQ42683558
Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinomaQ42805237
CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter contextQ43181834
Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradationQ43243061
Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activityQ44735758
A role for the non-phosphorylated form of yeast Snf1: tolerance to toxic cations and activation of potassium transportQ45218402
Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro.Q46211132
Comparison of features of the RNase activity of 5'-exonuclease-1 and 5'-exonuclease-2 of Saccharomyces cerevisiaeQ50115299
Phosphoproteomic analysis identifies proteins involved in transcription-coupled mRNA decay as targets of Snf1 signaling.Q54339361
Aberrant regulation of messenger RNA 3'-untranslated region in human cancer.Q54753141
Yeast histone genes show dosage compensationQ70152493
Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNAQ72331940
Characterization of NOT5 that encodes a new component of the Not protein complexQ74342700
Recombination and RNA processing: a common strand?Q75292815
Multifunctional deadenylase complexes diversify mRNA controlQ80854891
P433issue7
P921main subjectSaccharomyces cerevisiaeQ719725
P304page(s)212-228
P577publication date2017-07-03
P1433published inMicrobial cell (Graz, Austria)Q56298176
P1476titleThe interplay between transcription and mRNA degradation in Saccharomyces cerevisiae
P478volume4

Reverse relations

cites work (P2860)
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