KHSRP participates in manganese-induced neurotoxicity in rat striatum and PC12 cells

scientific article published on 16 July 2014

KHSRP participates in manganese-induced neurotoxicity in rat striatum and PC12 cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005910981
P356DOI10.1007/S12031-014-0367-7
P698PubMed publication ID25027559

P2093author name stringLingling Yang
Xia Ma
Jingling Han
Chunhua Wan
Jianya Zhao
Junkang Jiang
Shangshi Shi
Xiaoke Nie
P2860cites workThe RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signalingQ21145899
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayQ24548948
Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNAQ24624904
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR.Q24816506
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancerQ28118584
Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signalingQ28222344
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machineryQ28264688
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Involvement of striatal lipid peroxidation and inhibition of calcium influx into brain slices in neurobehavioral alterations in a rat model of short-term oral exposure to manganeseQ46381253
Endoplasmic reticulum stress signaling involvement in manganese-induced nerve cell damage in organotypic brain slice culturesQ47774217
p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.Q48492070
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Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax.Q48921606
Morphological changes and manganese content in the brains of rat pups subjected to subchronic poisoning with manganese chlorideQ51944496
Influence of the route of administration and the chemical form (MnCl 2 , MnO 2 ) on the absorption and cerebral distribution of manganese in ratsQ56834817
Manganese distribution in the brain and neurobehavioral changes following inhalation exposure of rats to three chemical forms of manganeseQ79773910
Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primatesQ28388232
Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAsQ28583467
RNA trafficking and stabilization elements associate with multiple brain proteinsQ28583604
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcriptsQ28594660
Manganese neurotoxicity: lessons learned from longitudinal studies in nonhuman primatesQ33425247
Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.Q33763825
Manganese-induced apoptosis in PC12 cells.Q34802108
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Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cellsQ35489449
Apoptosis Induced by Manganese on Neuronal SK-N-MC Cell Line: Endoplasmic Reticulum (ER) Stress and Mitochondria Dysfunction.Q35649216
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A predominantly nuclear protein affecting cytoplasmic localization of β-actin mRNA in fibroblasts and neuronsQ36324640
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Iron depletion increases manganese uptake and potentiates apoptosis through ER stressQ37164919
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAsQ37401219
Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's diseaseQ37522432
Are there common biochemical and molecular mechanisms controlling manganism and parkisonismQ37598121
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Activation of β-catenin by inhibitors of glycogen synthase kinase-3 ameliorates cisplatin-induced cytotoxicity and pro-inflammatory cytokine expression in HEI-OC1 cellsQ39021752
Anti-inflammatory effects of β-hydroxyisovalerylshikonin in BV2 microglia are mediated through suppression of the PI3K/Akt/NF-kB pathway and activation of the Nrf2/HO-1 pathwayQ39040831
MRI and PET studies of manganese-intoxicated monkeysQ39111403
Presynaptic and postsynaptic striatal dopaminergic function in patients with manganese intoxication: a positron emission tomography studyQ39114810
Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cellsQ39221508
Mitochondrial-mediated apoptosis in neural stem cells exposed to manganese.Q40058186
Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.Q40443410
Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase geneQ40444994
Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.Q40479277
Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741Q40766780
Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degenerationQ42492418
Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by TroloxQ42520354
Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brainQ42525785
Downregulation of the Wnt/β-catenin signaling pathway is involved in manganese-induced neurotoxicity in rat striatum and PC12 cellsQ42707173
Manganese regulates caspase-3 gene promoter activity by inducing Sp1 phosphorylation in PC12 cells.Q42715899
Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivoQ42726155
The case for manganese interaction with mitochondriaQ42779559
Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neuronsQ43685893
Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphateQ44184976
Developmental and regional changes in the neurochemical profile of the rat brain determined by in vivo 1H NMR spectroscopyQ44483762
Anti-apoptotic and pro-apoptotic effect of NEPP11 on manganese-induced apoptosis and JNK pathway activation in PC12 cells.Q45040732
P433issue2
P921main subjectstriatumQ1319792
neurotoxicityQ3338704
toxic encephalopathyQ7830379
P304page(s)454-465
P577publication date2014-07-16
P1433published inJournal of Molecular NeuroscienceQ15708870
P1476titleKHSRP participates in manganese-induced neurotoxicity in rat striatum and PC12 cells
P478volume55

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cites work (P2860)
Q28067566"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"
Q38479949Manganese Is Essential for Neuronal Health
Q37690759Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis
Q52316193Protective effect of vinpocetine against neurotoxicity of manganese in adult male rats
Q36327617Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin

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