Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications

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Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/NCPGASTHEP0055
P698PubMed publication ID16265071
P5875ResearchGate publication ID7502634

P2093author name stringScott L Friedman
P2860cites workEpithelial-mesenchymal transition and its implications for fibrosisQ24302042
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNRQ24551041
Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C.Q50584684
A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.Q50785680
Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cellsQ61763067
Apoptosis of T cells in the hepatic fibrotic tissue of the rat: a possible inducing role of hepatic myofibroblast-like cellsQ73175887
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cellsQ73322874
Is liver fibrosis reversible?Q73427092
History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cellsQ28190388
Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cellsQ28378160
Foxf1 +/- mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injuryQ28504652
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosisQ28582038
Nonalcoholic fatty liver diseaseQ29619354
Leptin induces increased α2(I) collagen gene expression in cultured rat hepatic stellate cellsQ31139462
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injuryQ33822590
Chemokines in liver inflammation and fibrosisQ33960600
Matrix as a modulator of hepatic fibrogenesisQ34391368
Cytokine receptors and signaling in hepatic stellate cellsQ34391388
Role of malondialdehyde-acetaldehyde adducts in liver injuryQ34528016
Transcriptional regulation of hepatic stellate cell activationQ34637612
Redox regulation of cytokine expression in Kupffer cellsQ35019103
Hepatic fibrosis: from bench to bedsideQ35020812
Vascular mediators in the injured liverQ35033793
Genetic polymorphisms and the progression of liver fibrosis: a critical appraisalQ35071658
Cirrhosis reversal: a duel between dogma and mythQ35749911
Liver fibrosis: from the bench to clinical targetsQ35759110
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosisQ36524368
Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responsesQ36591648
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat.Q38289678
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.Q39632325
Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasisQ40668665
Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factorsQ40679552
Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.Q40723449
Peroxisome proliferator-activated receptors and hepatic stellate cell activationQ41758990
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesisQ41933963
Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosisQ42600836
Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cellsQ42982855
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosisQ43858122
Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat liversQ43878352
The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.Q43910951
Leptin is essential for the hepatic fibrogenic response to chronic liver injuryQ44071052
Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15.Q44231634
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.Q44269271
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.Q44307079
Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migrationQ44493296
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectinQ44729228
Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoidsQ44749282
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linkingQ44929886
Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytesQ45054700
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomicsQ47580647
A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosisQ47839389
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)98-105
P577publication date2004-12-01
P1433published inNature Reviews Gastroenterology & HepatologyQ2108255
P1476titleMechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications
P478volume1

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