The protective effect of bee venom on fibrosis causing inflammatory diseases

scientific article

The protective effect of bee venom on fibrosis causing inflammatory diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/TOXINS7114758
P932PMC publication ID4663532
P698PubMed publication ID26580653

P50authorSok Cheon PakQ93060235
P2093author name stringKwan-Kyu Park
Woo-Ram Lee
P2860cites workAn atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endotheliumQ72068963
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Acupoint stimulation using bee venom attenuates formalin-induced pain behavior and spinal cord fos expression in ratsQ73224199
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A phase I study of the safety of honeybee venom extract as a possible treatment for patients with progressive forms of multiple sclerosisQ82851865
The molecular mechanism of bee venom phospholipase A2 inactivation by bolinaquinoneQ83278382
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Alcoholic liver disease: pathogenesis and new therapeutic targetsQ27690220
Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signalingQ28198809
Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compoundsQ28305475
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damageQ28506534
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Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
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The synergistic action of melittin and phospholipase A2 with lipid membranes: development of linear dichroism for membrane-insertion kinetics.Q33645822
Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currentsQ33701513
Atherosclerosis is an inflammatory diseaseQ33762068
Molecular mechanisms in intimal hyperplasiaQ33843561
The transcription factor NF-kappa B and the regulation of vascular cell functionQ34080327
Arterial endothelial dysfunction in baboons fed a high-cholesterol, high-fat dietQ34131613
The evolving role of Propionibacterium acnes in acneQ34397443
Emerging drugs for the treatment of acneQ34452033
Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responsesQ34456905
Modulation of the activity of secretory phospholipase A2 by antimicrobial peptidesQ34735131
Antiatherosclerotic effects of calcium channel blockersQ34759414
Melittin suppresses HIF-1α/VEGF expression through inhibition of ERK and mTOR/p70S6K pathway in human cervical carcinoma cellsQ34919916
Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanismsQ35034329
Protective effects of melittin on transforming growth factor-β1 injury to hepatocytes via anti-apoptotic mechanismQ39483563
The protective effect of bee venom against ethanol-induced hepatic injury via regulation of the mitochondria-related apoptotic pathwayQ39731077
Bee venom protects hepatocytes from tumor necrosis factor-alpha and actinomycin D.Q39733434
Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expressionQ39750850
Effect of bee venom on transforming growth factor-beta1-treated hepatocytesQ39751793
Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways.Q39804494
Induction of proinflammatory cytokines by a soluble factor of Propionibacterium acnes: implications for chronic inflammatory acne.Q39822745
Antitumor action and immune activation through cooperation of bee venom secretory phospholipase A2 and phosphatidylinositol-(3,4)-bisphosphate.Q40314980
Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunitQ40495126
Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) studyQ40873641
Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesisQ42726347
Bee Venom Reduces Atherosclerotic Lesion Formation via Anti-Inflammatory MechanismQ42828040
Bee Venom Inhibits Hepatic Fibrosis Through Suppression of Pro-Fibrogenic Cytokine ExpressionQ42915317
Tetrandrine attenuates lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized miceQ43207166
Inhibitory effects of bee venom on Propionibacterium acnes-induced inflammatory skin disease in an animal modelQ43477133
Cytokine expression in three mouse models of experimental hepatitisQ44145437
Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53.Q44315303
Programmed cellular death and atherogenesis: from molecular mechanisms to clinical aspectsQ44493591
Magnolol induces apoptosis in vascular smooth muscleQ44536455
The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic controlQ44545480
Effect of stent coating alone on in vitro vascular smooth muscle cell proliferation and apoptosisQ44639133
Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studiesQ44727519
Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout miceQ45042448
Water soluble fraction (<10 kDa) from bee venom reduces visceral pain behavior through spinal alpha 2-adrenergic activity in miceQ45225539
Protective effects of a polysaccharide from Hizikia fusiformis against ethanol toxicity in ratsQ46233119
Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient miceQ46432117
Mao (Ephedra sinica Stapf) protects against D-galactosamine and lipopolysaccharide-induced hepatic failureQ46792657
Melittin-induced membrane permeability: a nonosmotic mechanism of cell deathQ46920502
Exclusive expression of transmembrane TNF-alpha in mice reduces the inflammatory response in early lipid lesions of aortic sinusQ47955721
Adenovirus-encoded hammerhead ribozyme to Bcl-2 inhibits neointimal hyperplasia and induces vascular smooth muscle cell apoptosis.Q52538480
Structural and functional behavior of biologically active monomeric melittin.Q52572816
The protective role of hydrogen-rich saline in experimental liver injury in mice.Q52605852
Protective effect of melittin on inflammation and apoptosis in acute liver failure.Q53405958
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.Q53547282
Apamin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppressions of activated Akt and Erk signaling pathway.Q53595539
[C3 spinal cord ependymoma C03].Q55464331
Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell deathQ63303664
Bee venom phospholipase A2 protects against acetaminophen-induced acute liver injury by modulating regulatory T cells and IL-10 in miceQ35493627
D-galactosamine lethality model: scope and limitationsQ35806029
Anti-fibrotic effect of natural toxin bee venom on animal model of unilateral ureteral obstructionQ35808540
Expression of intercellular adhesion molecule-1 in atherosclerotic plaquesQ35830615
The Protective Effect of Apamin on LPS/Fat-Induced Atherosclerotic MiceQ35975443
Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis painQ36001934
Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implicationsQ36304061
Inflammation and atherosclerosis: novel insights into plaque formation and destabilizationQ36495025
Melittin: a membrane-active peptide with diverse functions.Q36670624
Mechanisms of vascular smooth muscle cell migrationQ36761041
Expression of tumor necrosis factor receptor-1 in arterial wall cells promotes atherosclerosisQ36848859
Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodelingQ36960275
Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosisQ37036076
Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitroQ37067058
Effect of honey bee venom on lewis rats with experimental allergic encephalomyelitis, a model for multiple sclerosisQ37320181
Epithelial-to-mesenchymal transitions in the liverQ37456459
Control of cell proliferation in atherosclerosis: insights from animal models and human studies.Q37630073
Bee venom in cancer therapyQ37959814
Regulation of TGF-β family signalling by ubiquitination and deubiquitinationQ38155982
HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs).Q38341138
Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparanQ38401839
Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expressionQ38459028
Bee venom phospholipase A2 prevents prion peptide induced-cell death in neuronal cellsQ38472872
Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expressionQ38511574
ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathwayQ38518281
Effects of bee venom against Propionibacterium acnes-induced inflammation in human keratinocytes and monocytesQ38887450
Apamin inhibits hepatic fibrosis through suppression of transforming growth factor β1-induced hepatocyte epithelial-mesenchymal transitionQ38989999
Protective effects of melittin on tumor necrosis factor-α induced hepatic damage through suppression of apoptotic pathway and nuclear factor-kappa B activationQ38990626
Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells.Q39011047
The protective effects of melittin on Propionibacterium acnes-induced inflammatory responses in vitro and in vivoQ39027281
Mechanism of interleukin-1β-induced proliferation in rat hepatic stellate cells from different levels of signal transductionQ39102557
Polyphenon-60 displays a therapeutic effect on acne by suppression of TLR2 and IL-8 expression via down-regulating the ERK1/2 pathwayQ39333793
Apamin inhibits THP-1-derived macrophage apoptosis via mitochondria-related apoptotic pathwayQ39358095
Melittin inhibits atherosclerosis in LPS/high-fat treated mice through atheroprotective actionsQ39456435
P275copyright licenseCreative Commons AttributionQ6905323
P433issue11
P921main subjectanti-inflammatory agentQ581996
venomQ3386847
P304page(s)4758-4772
P577publication date2015-11-16
P1433published inToxinsQ15724569
P1476titleThe protective effect of bee venom on fibrosis causing inflammatory diseases
P478volume7

Reverse relations

cites work (P2860)
Q42362242An Introduction to the Toxins Special Issue on "Bee and Wasp Venoms: Biological Characteristics and Therapeutic Application".
Q33598806Apamin suppresses biliary fibrosis and activation of hepatic stellate cells
Q60961629Bee venom acupuncture for circumscribed morphea in a patient with systemic sclerosis: A case report
Q28554831In Vitro and In Vivo Anti-Allergic and Anti-Inflammatory Effects of eBV, a Newly Developed Derivative of Bee Venom, through Modulation of IRF3 Signaling Pathway in a Carrageenan-Induced Edema Model
Q64094995Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni
Q38656223Insects: an underrepresented resource for the discovery of biologically active natural products
Q47113708The Effects of Melittin and Apamin on Airborne Fungi-Induced Chemical Mediator and Extracellular Matrix Production from Nasal Polyp Fibroblasts

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