Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling

scientific article published on 12 June 2013

Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1155/2013/928315
P932PMC publication ID3694547
P698PubMed publication ID23840100
P5875ResearchGate publication ID248384769

P2093author name stringLi Zhang
Feng Yang
Jianhua Zhu
Min Jin
Qingzhong Xiao
Qishan Chen
P2860cites workDifferential expression and activity of matrix metalloproteinases during flow-modulated vein graft remodelingQ47689201
IL-17 stimulates migration of carotid artery vascular smooth muscle cells in an MMP-9 dependent manner via p38 MAPK and ERK1/2-dependent NF-kappaB and AP-1 activationQ47912230
Expression of membrane-type matrix metalloproteinase in rabbit neointimal tissue and its correlation with matrix-metalloproteinase-2 activationQ48040095
Mobilization of CD34-positive bone marrow-derived cells after coronary stent implantation: impact on restenosisQ24294832
Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phaseQ24318760
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene familyQ24557562
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligandQ24644662
Collagenolytic activity in amphibian tissues: a tissue culture assayQ24648397
Effect of lumican on the migration of human mesenchymal stem cells and endothelial progenitor cells: involvement of matrix metalloproteinase-14Q27333560
A perivascular origin for mesenchymal stem cells in multiple human organsQ28131808
Matrix metalloproteinases: fold and function of their catalytic domainsQ28241713
FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcriptionQ28566755
Induction of matrix metalloproteinase-2 enhances systemic arterial contraction after hypoxiaQ28569035
Interleukin-lβ induces migration of rat arterial smooth muscle cells through a mechanism involving increased matrix metalloproteinase-2 activityQ28576629
The role of the matrix metalloproteinases during in vitro vessel formationQ28611471
Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9Q28616929
Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1Q29347013
Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanismQ29347072
Molecular mechanisms and clinical applications of angiogenesisQ29547314
Molecular regulation of vessel maturationQ29614540
Angiogenesis in health and diseaseQ29614541
Basic and therapeutic aspects of angiogenesisQ29615219
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistryQ29618605
The many roles of chemokines and chemokine receptors in inflammationQ29618880
How matrix metalloproteinases regulate cell behaviorQ29620360
Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cellsQ30441514
Functional interplay between endothelial nitric oxide synthase and membrane type 1 matrix metalloproteinase in migrating endothelial cellsQ30480215
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matricesQ30488978
Mechanisms underlying the impairment of ischemia-induced neovascularization in matrix metalloproteinase 2-deficient miceQ33275480
Cleavage and functional loss of human apolipoprotein E by digestion of matrix metalloproteinase-14.Q33355065
Matrix metalloproteinase-9 is essential for ischemia-induced neovascularization by modulating bone marrow-derived endothelial progenitor cellsQ33450208
An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculatureQ33751487
MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosisQ33906860
LRP: role in vascular wall integrity and protection from atherosclerosisQ34190034
Roles of PDGF in animal developmentQ34227429
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cellsQ34257800
Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions.Q50489152
MMP-2 Mediates Angiotensin II–Induced Hypertension Under the Transcriptional Control of MMP-7 and TACEQ50554929
Systemic sclerosis fibroblasts inhibit in vitro angiogenesis by MMP-12-dependent cleavage of the endothelial cell urokinase receptor.Q51143587
Elevated matrix metalloproteinase expression after stent implantation is associated with restenosis.Q51312971
Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling.Q52548108
Selective gene silencing of either MMP-2 or MMP-9 inhibits invasion of human saphenous vein smooth muscle cells.Q52855250
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.Q53606830
A proteomic approach to identify substrates of matrix metalloproteinase-14 in human plasma.Q53633793
Important role of the angiotensin II pathway in producing matrix metalloproteinase-9 in human thoracic aortic aneurysms.Q54459017
MT1-MMP promotes vascular smooth muscle dedifferentiation through LRP1 processing.Q54782284
Phagocytic NADPH Oxidase-Dependent Superoxide Production Stimulates Matrix Metalloproteinase-9Q59623212
Opposite effects of high glucose on MMP-2 and TIMP-2 in human endothelial cellsQ60595341
Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertensionQ61895228
Matrix Metalloproteinase (MMP)-3 Activates MMP-9 Mediated Vascular Smooth Muscle Cell Migration and Neointima Formation in MiceQ63915756
Inhibition of matrix metalloproteinase-9 reduces in vitro invasion and angiogenesis in human microvascular endothelial cellsQ64379249
Crucial role of membrane type 1 matrix metalloproteinase (MT1- MMP) in RhoA/Rac1-dependent signaling pathways in thrombin- stimulated endothelial cellsQ64379708
The genomic response of tumor cells to hypoxia and reoxygenation. Differential activation of transcription factors AP-1 and NF-kappa BQ70824259
Transmural pressure induces matrix-degrading activity in porcine arteries ex vivoQ73188770
Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid arteryQ73254515
Remodeling of carotid artery is associated with increased expression of matrix metalloproteinases in mouse blood flow cessation modelQ73265468
The role of protein-tyrosine phosphorylation and gelatinase production in the migration and proliferation of smooth muscle cellsQ73515090
Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasiaQ73854485
Increased expression of membrane-type matrix metalloproteinase and preferential localization of matrix metalloproteinase-2 to the neointima of balloon-injured rat carotid arteriesQ74093557
Reduced angiogenesis and tumor progression in gelatinase A-deficient miceQ74309789
Characterization of the role of the "MT-loop": an eight-amino acid insertion specific to progelatinase A (MMP2) activating membrane-type matrix metalloproteinasesQ74509484
MT1-MMP, but not secreted MMPs, influences the migration of human microvascular endothelial cells in 3-dimensional collagen gelsQ74720760
MMP-7 (matrilysin) accelerated growth of human umbilical vein endothelial cellsQ77542083
Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injuryQ78460679
Involvement of integrins, MAPK, and NF-kappaB in regulation of the shear stress-induced MMP-9 expression in endothelial cellsQ79437916
Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesisQ80845141
Hypoxia of endothelial cells leads to MMP-2-dependent survival and deathQ81321980
MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferationQ82284786
Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatinQ82915890
Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertensionQ83538631
Matrix metalloproteinase 2 and tissue inhibitors of metalloproteinases regulate human aortic smooth muscle cell migration during in vitro agingQ83978407
Modulation of the angiogenic phenotype of normal and systemic sclerosis endothelial cells by gain-loss of function of pentraxin 3 and matrix metalloproteinase 12Q84309344
Activation of matrix metalloproteinase-9 is associated with mobilization of bone marrow-derived cells after coronary stent implantationQ84963515
Effects of matrix metalloproteinase-1 on the myogenic differentiation of bone marrow-derived mesenchymal stem cells in vitroQ85239941
An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivoQ86434879
Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration.Q38294069
NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-IIQ39124068
Role of MT1-MMP in estrogen-mediated cellular processes of intimal hyperplasiaQ39726291
Early increased MT1-MMP expression and late MMP-2 and MMP-9 activity during Angiotensin II induced aneurysm formationQ39756130
A role of matrix metalloproteinase-8 in atherosclerosisQ40000765
Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenationQ40736944
The emerging concept of vascular remodelingQ40740827
Apolipoprotein E inhibition of vascular smooth muscle cell proliferation but not the inhibition of migration is mediated through activation of inducible nitric oxide synthaseQ40887026
Activation mechanisms of matrix metalloproteinases.Q41482018
Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9.Q42186142
Regulation of vascular smooth muscle cell expression and function of matrix metalloproteinases is mediated by estrogen and progesterone exposureQ42442551
Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularizationQ42741392
Different activation forms of MMP-2 oppositely affect the fate of endothelial cellsQ43195169
Homocysteine modulates the proteolytic potential of human arterial smooth muscle cells through a reactive oxygen species dependant mechanismQ43269924
Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stressQ43649151
Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodelingQ43670946
Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotypeQ43975299
MMP-3 (5A/6A) polymorphism does not influence human smooth muscle cell invasionQ44231162
Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen SpeciesQ44443254
Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins.Q44456620
High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes.Q44474834
Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A.Q44511121
Matrix Metalloproteinase-2 and −9 Differentially Regulate Smooth Muscle Cell Migration and Cell-Mediated Collagen OrganizationQ44612994
Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cellsQ44631572
Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.Q44995477
Angiotensin II induces MMP-2 in a p47phox-dependent mannerQ45238311
Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertensionQ46106295
Estrogen deficiency-induced alterations of vascular MMP-2, MT1-MMP, and TIMP-2 in ovariectomized rats.Q46235331
Chronic hypoxia accelerates the progression of atherosclerosis in apolipoprotein E-knockout miceQ46938472
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.Q34542211
Adult bone marrow stem cells for cell and gene therapies: implications for greater use.Q34669002
Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinasesQ35056901
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young ratsQ35085406
Pulsatile ex vivo perfusion of human saphenous vein grafts under controlled pressure conditions increases MMP-2 expressionQ35141088
Mechanisms of cardiovascular remodeling in hyperhomocysteinemiaQ35173832
Matrix metalloproteinases as modulators of inflammation and innate immunityQ35852281
Bone marrow stromal cells stimulate an angiogenic program that requires endothelial MT1-MMP.Q35918685
Chemokines in the pathogenesis of vascular diseaseQ35932790
Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular diseaseQ36009930
Influence of matrix metalloproteinase genotype on cardiovascular disease susceptibility and outcome.Q36240875
Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substratesQ36305029
Smoking, metalloproteinases, and vascular diseaseQ36336918
MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.Q36402867
Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular diseaseQ36477722
Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cellsQ36508733
Role of matrix metalloproteinase-8 in atherosclerosisQ36567357
Angiogenesis and chronic inflammation: cause or consequence?Q36801097
Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishmentQ36943114
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veinsQ36953739
NADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells.Q36987722
Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesisQ37061090
Matrix metalloproteinase-1 promotes muscle cell migration and differentiationQ37071885
Hypoxia and placental remodelling.Q37082653
Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in miceQ37100777
Oxidative stress and the development of diabetic retinopathy: contributory role of matrix metalloproteinase-2.Q37195371
Inhibition of smooth muscle cell migration and neointima formation in vein grafts by overexpression of matrix metalloproteinase-3.Q37276960
Inflammatory cytokines in vascular dysfunction and vascular diseaseQ37315106
Inflammation, growth factors, and pulmonary vascular remodelingQ37531255
Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.Q37561940
Emerging biology of vascular wall progenitor cells in health and diseaseQ37614679
Hypoxia-driven angiogenesis: role of tip cells and extracellular matrix scaffolding.Q37716522
Matrix metalloproteinase inhibition therapy for vascular diseasesQ37983293
Inflammatory mechanisms in atherosclerosis: the impact of matrix metalloproteinases.Q38004039
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectenzymeQ8047
P304page(s)928315
P577publication date2013-06-12
P1433published inMediators of InflammationQ2144494
P1476titleMatrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling
P478volume2013