Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration.

scientific article published on 05 December 2001

Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109124200
P698PubMed publication ID11739389

P50authorDebi SwertfegerQ71702455
P2093author name stringGuojun Bu
David Y Hui
P2860cites workApolipoprotein E and atherosclerosisQ33959445
Lipoprotein binding and endosomal itinerary of the low density lipoprotein receptor-related protein in rat liverQ34322965
Inhibition of Ca2+ accumulation in mitogen-activated lymphocytes: role of membrane-bound plasma lipoproteinsQ36402608
Identification of a lymphocyte surface receptor for low density lipoprotein inhibitor, an immunoregulatory species of normal human serum low density lipoproteinQ40152561
Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cellsQ40819741
Apolipoprotein E inhibition of vascular smooth muscle cell proliferation but not the inhibition of migration is mediated through activation of inducible nitric oxide synthaseQ40887026
A minimally lipidated form of cell-derived apolipoprotein E exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteinsQ41056322
Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related proteinQ41150323
Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA.Q42622076
Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitroQ45081026
The mouse low density lipoprotein receptor gene: cDNA sequence and exon-intron structureQ48127965
Perlecan mediates the antiproliferative effect of apolipoprotein E on smooth muscle cells. An underlying mechanism for the modulation of smooth muscle cell growth?Q54069183
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transductionQ22254170
Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular diseaseQ24312335
Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phaseQ24318760
Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptorQ24564351
Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteinsQ24609758
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Morpholino antisense oligomers: design, preparation, and propertiesQ28243074
Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonistQ28286186
Apolipoprotein E: cholesterol transport protein with expanding role in cell biologyQ28294791
Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasiaQ28379241
Evolution of the apolipoprotein E receptor 2 gene by exon lossQ28513255
Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectinQ30470527
Apolipoprotein E: a cholesterol transport protein with lipid transport-independent cell signaling propertiesQ32068720
Lipoprotein receptors in the liver. Control signals for plasma cholesterol trafficQ33822165
Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell lineQ33848287
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
lipoproteinQ28350
P1104number of pages6
P304page(s)4141-4146
P577publication date2001-12-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleLow density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration
P478volume277

Reverse relations

cites work (P2860)
Q36749726Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice
Q50150331Apolipoprotein E Gene Polymorphism and Subclinical Carotid Atherosclerosis: The Northern Manhattan Study
Q35662397Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway
Q55416365Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation.
Q44511121Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A.
Q34537514Apolipoprotein E inhibition of vascular hyperplasia and neointima formation requires inducible nitric oxide synthase
Q35919265Apolipoprotein E-induced cell signaling in the vessel wall
Q92970082Apoproteins E, A-I, and SAA in Macrophage Pathobiology Related to Atherogenesis
Q34443186Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability
Q52109257Coaxing the LDL receptor family into the fold.
Q35181677Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling
Q51794142Environmental enrichment counteracts Alzheimer's neurovascular dysfunction in TgCRND8 mice.
Q40611910Essential role of the low density lipoprotein receptor-related protein in vascular smooth muscle cell migration
Q59792122Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells
Q34192711LDL Receptor‐Related Proteins in Neurodevelopment
Q37216064LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies
Q24307377LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration
Q36540227LRP-1 silencing prevents malignant cell invasion despite increased pericellular proteolytic activities
Q28508492LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation
Q36486210Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family
Q64086638Low Density Receptor-Related Protein 1 Interactions With the Extracellular Matrix: More Than Meets the Eye
Q38355997Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts.
Q40449433Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta).
Q36535157Low-density lipoprotein receptor-related protein (LRP)-mediated clearance of activated blood coagulation co-factors and proteases: clearance mechanism or regulation?
Q36960275Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling
Q36825335Metabolic Dysfunction in Pulmonary Arterial Hypertension
Q36130930Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models
Q28570390Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae
Q42813779Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function
Q42590363Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation
Q24644020Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain
Q42541410Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells
Q44570731Testing the role of apoA-I, HDL, and cholesterol efflux in the atheroprotective action of low-level apoE expression
Q37331185The P2Y2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells
Q24305980The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway
Q40582221The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.
Q30308805The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces
Q40571781The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.

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