NADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells.

scientific article published on May 2012

NADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.1048
P932PMC publication ID3703153
P698PubMed publication ID22290850
P5875ResearchGate publication ID221792259

P50authorNorifumi UraoQ54186237
P2093author name stringMasuko Ushio-Fukai
Tohru Fukai
Ronald D McKinney
P2860cites workLow-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilizationQ24646424
Vanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen speciesQ24720804
Metabolic regulation of hematopoietic stem cells in the hypoxic nicheQ27023590
Circulating endothelial progenitor cells and cardiovascular outcomesQ28271167
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cellsQ28288970
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxiaQ28582257
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stressQ29615562
Matrix metalloproteinases and the regulation of tissue remodellingQ29618747
Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemia.Q31167736
Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrowQ33283654
Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function.Q33649852
Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α ProteinQ34186417
Targeting stem cell niches and trafficking for cardiovascular therapyQ34475689
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic nicheQ36059646
MT1-MMP: a potent modifier of pericellular microenvironment.Q36141763
Bone-marrow haematopoietic-stem-cell nichesQ36402226
The stem cell niches in boneQ36467113
Redox signaling in angiogenesis: role of NADPH oxidaseQ36509981
A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrixQ36647946
Hypoxia-inducible factor 1 (HIF-1) pathwayQ36966537
Uncertainty in the niches that maintain haematopoietic stem cellsQ37103620
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activationQ37353163
The hematopoietic stem cell niche: low in oxygen but a nice place to be.Q37590760
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodellingQ37694105
Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenanceQ37746565
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell NicheQ37777514
The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategiesQ37800633
Regulation of reactive oxygen species in stem cells and cancer stem cells.Q37859337
Reactive oxygen species: are they important for haematopoiesis?Q37867250
Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathwayQ39941633
LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent mannerQ40024594
Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity.Q40424738
Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemiaQ42535142
The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidneyQ42738380
MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilizationQ43172703
Redox regulation of stem and progenitor cellsQ43249901
Hypoxia activates Akt and induces phosphorylation of GSK-3 in PC12 cellsQ43546852
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic nicheQ45870881
Function of oxidative stress in the regulation of hematopoietic stem cell-niche interactionQ46980493
N-acetyl-cysteine decreases the matrix-degrading capacity of macrophage-derived foam cells: new target for antioxidant therapy?Q47924123
Role of the plasma membrane ROS-generating NADPH oxidase in CD34+ progenitor cells preservation by hypoxia.Q50961958
Respiratory burst of neutrophils is not required for stem cell mobilization in miceQ73309653
Angiogenic factors reconstitute hematopoiesis by recruiting stem cells from bone marrow microenvironmentQ73508553
Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen speciesQ79492733
The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditionsQ80476978
P4510describes a project that usesImageJQ1659584
P433issue5
P1104number of pages12
P304page(s)923-934
P577publication date2012-05-01
P1433published inStem CellsQ15724411
P1476titleNADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells
P478volume30

Reverse relations

cites work (P2860)
Q91025226Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells
Q30666915Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function
Q26772290Critical Roles of Reactive Oxygen Species in Age-Related Impairment in Ischemia-Induced Neovascularization by Regulating Stem and Progenitor Cell Function
Q34614391Critical role of endothelial hydrogen peroxide in post-ischemic neovascularization
Q59810180Global Identification of HIF-1α Target Genes in Benzene Poisoning Mouse Bone Marrow Cells
Q36339217Impaired compensation to femoral artery ligation in diet-induced obese mice is primarily mediated via suppression of collateral growth by Nox2 and p47phox
Q34240822Increased antioxidant defense mechanism in human adventitia-derived progenitor cells is associated with therapeutic benefit in ischemia
Q41509350Lysophosphatidic acid rescues bone mesenchymal stem cells from hydrogen peroxide-induced apoptosis
Q36960275Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling
Q35749601Mechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responses
Q37584923Mechanotransduction drives post ischemic revascularization through K(ATP) channel closure and production of reactive oxygen species.
Q61797275Modification of Cardiac Progenitor Cell-Derived Exosomes by miR-322 Provides Protection against Myocardial Infarction through Nox2-Dependent Angiogenesis
Q39433122NADPH Oxidases, Angiogenesis, and Peripheral Artery Disease.
Q35985407NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress
Q46467341Nox2 and Nox4 regulate self-renewal of murine induced-pluripotent stem cells
Q37264003Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling
Q57464711Oxidant Signaling Mediated by Nox2 in Neutrophils Promotes Regenerative Myelopoiesis and Tissue Recovery following Ischemic Damage
Q34097015Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb
Q38206835Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment
Q50457515Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.
Q42547128Redox and metabolic regulation of stem/progenitor cells and their niche
Q26851313Redox regulation of stem/progenitor cells and bone marrow niche
Q38263008Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
Q26825809To breathe or not to breathe: the haematopoietic stem/progenitor cells dilemma

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