NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II

scientific article published on 30 September 2011

NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E10-12-0971
P932PMC publication ID3216667
P698PubMed publication ID21965295

P50authorAgnes GörlachQ97309728
P2093author name stringMaximilian Burger
John Hess
Isabel Diebold
Andreas Petry
P2860cites workStress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylaseQ24310456
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardinQ24311484
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologuesQ24532085
Is urotensin-II the new endothelin?Q24672927
Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-kappaB pathwayQ28270955
The FoxO codeQ28275268
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB siteQ28286400
FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcriptionQ28566755
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 proteinQ28577209
Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cellsQ28582797
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3aQ28592736
FoxO3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosisQ33604706
MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI StudyQ33820443
The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1.Q33907086
Matrix metalloproteinases: they're not just for matrix anymore!Q34360566
Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cellsQ34379685
Forkhead transcription factor FOXO3a is a negative regulator of angiogenic immediate early gene CYR61, leading to inhibition of vascular smooth muscle cell proliferation and neointimal hyperplasiaQ34603743
FoxOs at the crossroads of cellular metabolism, differentiation, and transformationQ35770614
Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular diseaseQ36477722
Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a.Q36755423
Dynamic FoxO transcription factorsQ36889897
Urotensin-II and cardiovascular remodelingQ36995672
FoxO proteins: cunning concepts and considerations for the cardiovascular systemQ37195595
FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases.Q37334058
Matrix metalloproteinases in atherothrombosis.Q37708600
Role of urotensin II in health and diseaseQ37737495
Forkhead homeobox type O transcription factors in the responses to oxidative stressQ37771334
Structural basis for DNA recognition by FOXO proteinsQ37819155
The complex biology of FOXO.Q37858545
FOXO3 modulates endothelial gene expression and function by classical and alternative mechanismsQ38346760
NOX2 and NOX4 mediate proliferative response in endothelial cells.Q40229689
JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.Q40398942
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.Q40493379
Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularizationQ42130997
Urotensin II is raised in children with congenital heart diseaseQ42833174
Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinaseQ43633744
Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen SpeciesQ44443254
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genesQ46402217
Critical role of Mst1 in vascular remodeling after injury.Q46551613
Increased plasma urotensin-II levels are associated with diabetic retinopathy and carotid atherosclerosis in Type 2 diabetesQ46703588
Forkhead factor, FOXO3a, induces apoptosis of endothelial cells through activation of matrix metalloproteinases.Q52583886
Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia.Q53670501
Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertensionQ61895228
Ca(2+)-dependent Cl(-) channels in mouse and rabbit aortic smooth muscle cells: regulation by intracellular Ca(2+) and NOQ73188696
Factor Xa releases matrix metalloproteinase-2 (MMP-2) from human vascular smooth muscle cells and stimulates the conversion of pro-MMP-2 to MMP-2: role of MMP-2 in factor Xa-induced DNA synthesis and matrix invasionQ74211090
Isolation of vascular smooth muscle cells from a single murine aortaQ78675064
Urotensin-II in the lung: a matter for vascular remodelling and pulmonary hypertension?Q79828440
Human urotensin II modulates collagen synthesis and the expression of MMP-1 in human endothelial cellsQ80908840
From worm to human: bioinformatics approaches to identify FOXO target genesQ81176620
Deciphering the "matrix" in pulmonary vascular remodellingQ81702646
Increased plasma levels of endothelin-1 and urotensin-II in patients with coronary heart diseaseQ83912518
P4510describes a project that usesImageJQ1659584
P433issue22
P304page(s)4424-4434
P577publication date2011-09-30
P1433published inMolecular Biology of the CellQ2338259
P1476titleNOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II
P478volume22

Reverse relations

cites work (P2860)
Q89697823Early Programming of Adult Systemic Essential Hypertension
Q39178512Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells
Q39385262FOXO transcription factors at the interface of metabolism and cancer
Q50077490FOXO3a (Forkhead Transcription Factor O Subfamily Member 3a) Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13).
Q35559300Fad104, a positive regulator of adipocyte differentiation, suppresses invasion and metastasis of melanoma cells by inhibition of STAT3 activity
Q57823589Increasing autophagy does not affect neurogenic muscle atrophy
Q91259885Matrix metalloproteinases in pro-atherosclerotic arterial remodeling
Q36960275Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling
Q38596162NADPH oxidases-do they play a role in TRPC regulation under hypoxia?
Q36218362Oxidative Stress Induces Mouse Follicular Granulosa Cells Apoptosis via JNK/FoxO1 Pathway
Q58073566Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a ‘mixed matrix’
Q37334463Polymerase delta interacting protein 2 sustains vascular structure and function.
Q34097015Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb
Q36587602Reactive oxygen species in vascular formation and development
Q64060576Regulation of Smooth Muscle Cell Proliferation by NADPH Oxidases in Pulmonary Hypertension
Q33599835The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features
Q39195350The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system
Q28085161The role of oxidative stress and autophagy in atherosclerosis
Q35014906Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway
Q50796108Urotensin II receptor antagonism confers vasoprotective effects in diabetes associated atherosclerosis: studies in humans and in a mouse model of diabetes.
Q89338823p47phox-Dependent Reactive Oxygen Species Stimulate Nuclear Translocation of the FoxO1 Transcription Factor During Metabolic Inhibition in Cardiomyoblasts

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