Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.

scientific article published on 23 July 2009

Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.BBAMCR.2009.07.004
P698PubMed publication ID19631700
P5875ResearchGate publication ID26694870

P50authorCarlos López OtínQ2919877
Alicia R FolguerasQ56879250
Sandra CabreraQ80803973
P2093author name stringMiriam Fanjul-Fernández
P2860cites workThe consensus coding sequences of human breast and colorectal cancersQ27861035
Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-κB SignalingQ56648795
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)3-19
P577publication date2009-07-23
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleMatrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models
P478volume1803

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cites work (P2860)
Q38202093A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging
Q34796034A glimpse of matrix metalloproteinases in diabetic nephropathy
Q38893256A new front in cell invasion: The invadopodial membrane
Q41565401A novel mechanism of latency in matrix metalloproteinases
Q47252258A significant association exists between receptor tyrosine kinase-like orphan receptor 2 gene variants and the OPG/RANKL ratio in human plasma
Q39541274Absence of Thy-1 results in TGF-β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblasts
Q28082608Airway Remodeling in Chronic Obstructive Pulmonary Disease and Asthma: the Role of Matrix Metalloproteinase-9
Q40948096Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging.
Q55405947Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia.
Q95856998Association of matrix metalloproteinases 3 and 9 single nucleotide polymorphisms with breast cancer risk: A case-control study
Q35321883BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection
Q35755517CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis
Q42453418Calcifying Cystic Odontogenic Tumour: immunohistochemical expression of matrix metalloproteinases, their inhibitors (TIMPs and RECK) and inducer (EMMPRIN).
Q50109671Cancer Susceptibility Models in Protease-Deficient Mice
Q92503815Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling
Q51696474Cardioprotective effect of novel sulphonamides-1,3,5-triazine conjugates against ischaemic-reperfusion injury via selective inhibition of MMP-9.
Q36921347Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize.
Q91577811Cellular Mechanisms of Aortic Aneurysm Formation
Q28752317Comparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals
Q54974391Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix.
Q64249883Curcumin and Intestinal Inflammatory Diseases: Molecular Mechanisms of Protection
Q48297033Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma
Q43237233Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase
Q53063777Delayed skin wound repair in proline-rich protein tyrosine kinase 2 knockout mice.
Q89964334Destroy to Rebuild: The Connection Between Bone Tissue Remodeling and Matrix Metalloproteinases
Q34202064Differential spatio-temporal regulation of MMPs in the 5xFAD mouse model of Alzheimer's disease: evidence for a pro-amyloidogenic role of MT1-MMP.
Q37609680Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study
Q34017819Diffusion of MMPs on the surface of collagen fibrils: the mobile cell surface-collagen substratum interface
Q38408377Digital hypothermia inhibits early lamellar inflammatory signalling in the oligofructose laminitis model
Q38126397Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking
Q90179000ERK1/ATF-2 signaling axis contributes to interleukin-1β-induced MMP-3 expression in dermal fibroblasts
Q34105182Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: recruiting histone deacetylase and inhibiting activator protein 1 transcription factors
Q47213987Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro
Q93118372Emerging regulators of vascular smooth muscle cell migration
Q51699120Endometrial hyperplasia-related inflammation: its role in the development and progression of endometrial hyperplasia.
Q89637357Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface
Q38062851Epigenetic regulation of mmp-9 gene expression
Q36173467Euphorbia humifusa Willd exerts inhibition of breast cancer cell invasion and metastasis through inhibition of TNFα-induced MMP-9 expression.
Q61801606Evaluation of Collagen Fibers, MMP2, MMP9, 8-OHdG and Apoptosis in the Aorta of Ovariectomized LDL Knockout Mice Submitted to Aerobic Exercise
Q33794488Evolutionary Analysis Predicts Sensitive Positions of MMP20 and Validates Newly- and Previously-Identified MMP20 Mutations Causing Amelogenesis Imperfecta
Q33745045Evolutionary history of tissue kallikreins
Q36408629Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases
Q39016000Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization
Q36833684Expression and Activity of Metalloproteinases in Depression.
Q28300689Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma
Q53115663Extracellular β-NAD(+) inhibits interleukin-1-induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts.
Q48543248Fell‐Muir Lecture: Metalloproteinases: from demolition squad to master regulators
Q35643324Fetal hypoxia and programming of matrix metalloproteinases.
Q37285451Flow-induced HDAC1 phosphorylation and nuclear export in angiogenic sprouting.
Q40736375Frequency of the common promoter polymorphism MMP2 -1306 C>T in a population from central Bulgaria
Q38196442Functional polymorphisms in the matrix metalloproteinase genes and their association with bladder cancer risk and recurrence: a mini-review.
Q28817275Genetic mechanisms of bone digestion and nutrient absorption in the bone-eating worm Osedax japonicus inferred from transcriptome and gene expression analyses
Q35114053Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis
Q49719103Glioma infiltration and extracellular matrix: key players and modulators.
Q52900205Hemorrhagic metalloproteinase, Cc HSM-III, isolated from Cerastes cerastes venom: Purification and biochemical characterization.
Q51763123Histone tail cleavage as a novel epigenetic regulatory mechanism for gene expression.
Q30359755Hyperhomocysteinemia, MMPs and Cochlear Function: A Short Review.
Q51738202IL-12-mediated transcriptional regulation of matrix metalloproteinases.
Q53589745Immunohistochemical analysis on MMP-2 and MMP-9 for wound age determination.
Q58701508Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage
Q26766038Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke
Q35103645In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis
Q90230698Increased Ratio of Matrix Metalloproteinase-9 (MMP-9)/Tissue Inhibitor Metalloproteinase-1 from Alveolar Macrophages in Chronic Asthma with a Fast Decline in FEV1 at 5-Year Follow-up
Q92839001Inhibition of SERPINE2/protease nexin-1 by a monoclonal antibody attenuates airway remodeling in a murine model of asthma
Q34225110Innate immune system and tissue regeneration in planarians: an area ripe for exploration
Q49981026Interleukin-1 receptor antagonist inhibits angiogenesis in gastric cancer
Q33812663Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines.
Q40742201Investigation of the role of MMP3 -1171insA polymorphism in cutaneous malignant melanoma - a preliminary study
Q38265674Is there new hope for therapeutic matrix metalloproteinase inhibition?
Q42124894Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity
Q46168368Kruppel-like factor 4 regulates matrix metalloproteinase and aggrecanase gene expression in chondrocytes.
Q30635913Loss of Drosophila pseudouridine synthase triggers apoptosis-induced proliferation and promotes cell-nonautonomous EMT.
Q35991636Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid
Q34328435MMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia
Q60048644MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors
Q35543498Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats
Q52882920Matrix Metalloproteinase-9 rs17576 Gene Polymorphism and Behçet's Disease: Is There an Association?
Q89660177Matrix Metalloproteinases in Diabetic Kidney Disease
Q57082617Matrix Proteases and the Degradome
Q97528477Matrix levels of metalloproteinase-2 (MMP-2) and toxicity evaluation of carbonate apatite-based endodontic sealer in rat subcutaneous implantation
Q36097959Matrix metalloprotease-1a promotes tumorigenesis and metastasis
Q36850412Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses
Q34136881Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler's murine encephalomyelitis.
Q50218199Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.
Q51835071Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage.
Q35043525Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review.
Q37864524Matrix metalloproteinases and their clinical relevance in urinary bladder cancer
Q52639936Matrix metalloproteinases expression in spontaneous canine histiocytic sarcomas and its xenograft model.
Q34485163Matrix metalloproteinases in a sea urchin ligament with adaptable mechanical properties
Q27004621Matrix metalloproteinases in kidney homeostasis and diseases
Q38024303Matrix metalloproteinases: a review of their structure and role in systemic sclerosis
Q36960275Matrix metalloproteinases: inflammatory regulators of cell behaviors in vascular formation and remodeling
Q64057399Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis
Q51155840Matrix-metalloproteinases as targets for controlled delivery in cancer: An analysis of upregulation and expression.
Q37808263Mechanical loading, cartilage degradation, and arthritis
Q93027832Mechanisms of physiological tissue remodeling in animals: Manipulating tissue, organ, and organism morphology
Q37224415Mechanotransduction and cartilage integrity
Q39480185Metalloproteinase Changes in Diabetes
Q38237985Metastasis review: from bench to bedside
Q34768858Metzincin proteases and their inhibitors: foes or friends in nervous system physiology?
Q53063262Microvesicles shed from fibroblasts act as metalloproteinase carriers in a 3-D collagen matrix.
Q53483201Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.
Q47232003Molecular evolution of matrix metalloproteinase 20.
Q58816167Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo
Q52323503Molecular mechanisms of fission in echinoderms: Transcriptome analysis.
Q52682069Monoclonal antibodies against metzincin targets.
Q35896921Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis, and tooth eruption
Q55012871NEDD9 stimulated MMP9 secretion is required for invadopodia formation in oral squamous cell carcinoma.
Q42239363New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.
Q48145690Noncanonical Decapentaplegic Signaling Activates Matrix Metalloproteinase 1 To Restrict Hedgehog Activity and Limit Ectopic Eye Differentiation in Drosophila.
Q41373666Nuclear matrix metalloproteinases: functions resemble the evolution from the intracellular to the extracellular compartment
Q57116710Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer
Q47099030Overexpression of carbonic anhydrase IX induces cell motility by activating matrix metalloproteinase-9 in human oral squamous cell carcinoma cells
Q92635860Petunidin, a B-ring 5'-O-Methylated Derivative of Delphinidin, Stimulates Osteoblastogenesis and Reduces sRANKL-Induced Bone Loss
Q38725320Pharmacodynamic considerations in the use of matrix metalloproteinase inhibitors in cancer treatment
Q52663819Physiologic facet capsule stretch can induce pain & upregulate matrix metalloproteinase-3 in the dorsal root ganglia when preceded by a physiological mechanical or nonpainful chemical exposure.
Q28581964Physiological loading of joints prevents cartilage degradation through CITED2
Q36857921Placental membrane-type metalloproteinases (MT-MMPs): Key players in pregnancy.
Q93017651Post-Translational Modification-Dependent Activity of Matrix Metalloproteinases
Q98465022Progestins Inhibit Interleukin-1β-Induced Matrix Metalloproteinase 1 and Interleukin 8 Expression via the Glucocorticoid Receptor in Primary Human Amnion Mesenchymal Cells
Q58659036Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta
Q60110844Proteases Shape the Chlamydomonas Secretome: Comparison to Classical Neuropeptide Processing Machinery
Q54118684Protective Effects of LSGYGP from Fish Skin Gelatin Hydrolysates on UVB-Induced MEFs by Regulation of Oxidative Stress and Matrix Metalloproteinase Activity.
Q35189024Protective roles of matrix metalloproteinases: from mouse models to human cancer
Q39174470Proteolytic activity in the meibomian gland: Implications to health and disease
Q24609283Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales
Q38861547Pseudomonas aeruginosa quorum-sensing signaling molecule N-3-oxododecanoyl homoserine lactone induces matrix metalloproteinase 9 expression via the AP1 pathway in rat fibroblasts
Q64260627Recent advances in understanding the regulation of metalloproteinases
Q30008871Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)
Q33719352Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10
Q41807804Riding the metalloproteinase roller coaster
Q89848351Role of MMP-1, MMP-8 and MMP-9 gene polymorphisms in preterm birth
Q44000996Role of matrix metalloproteinases in migration and neurotrophic properties of nasal olfactory stem and ensheathing cells
Q37540188Role of microRNA-mediated MMP regulation in the treatment and diagnosis of malignant tumors
Q52722878Roles of NF-κB Signaling in the Regulation of miRNAs Impacting on Inflammation in Cancer.
Q27306938Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer
Q37707926Significance of impaired serum gelatinases activities in metabolic syndrome.
Q92543274Skullcapflavone II Inhibits Degradation of Type I Collagen by Suppressing MMP-1 Transcription in Human Skin Fibroblasts
Q55620580Some Biological Consequences of the Inhibition of Na,K-ATPase by Translationally Controlled Tumor Protein (TCTP).
Q91776664Study of Gene Expression Profiles of Breast Cancers in Indian Women
Q33598697Sulfonate-containing thiiranes as selective gelatinase inhibitors
Q39329438Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Q61804521Syzygium aromaticum aqueous extract inhibits human neutrophils myeloperoxidase and protects mice from LPS-induced lung inflammation
Q58750549TFPI-2 Protects Against Gram-Negative Bacterial Infection
Q48502109Targeting Netrin-1 in glioblastoma stem-like cells inhibits growth, invasion, and angiogenesis.
Q47748198Targeting the Hemopexin-like Domain of Latent Matrix Metalloproteinase-9 (proMMP-9) with a Small Molecule Inhibitor Prevents the Formation of Focal Adhesion Junctions.
Q92638925Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
Q50501810Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-β in renovascular hypertension-induced cardiac hypertrophy.
Q39095749The DNA hypomethylating agent, 5-aza-2'-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells.
Q47156148The association of matrix metalloproteinase-9 promoter polymorphisms with gastric cancer risk: a meta-analysis
Q33772478The evolution of extracellular matrix
Q89544588The expression of MMP-1 and MMP-9 is up-regulated by smooth muscle cells after their cross-talk with macrophages in high glucose conditions
Q42233338The first MMP in sepsis
Q36243972The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma
Q36613779The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis
Q59794870The role of matrix metalloproteinase-9 as a prognostic biomarker in papillary thyroid cancer
Q47430650Thrombin Enhanced Matrix Metalloproteinase-9 Expression and Migration of SK-N-SH Cells via PAR-1, c-Src, PYK2, EGFR, Erk1/2 and AP-1.
Q39191612Towards integrating extracellular matrix and immunological pathways.
Q85267547Treatment of dermal fibroblasts with GPI-anchored human TIMP-1 protein moderates processes linked to scar formation
Q41180159Vascular Invasion and Stromal S100A4 Expression at the Invasive Front of Colorectal Cancer are Novel Determinants and Tumor Prognostic Markers
Q38988976Zerumbone suppresses IL-1β-induced cell migration and invasion by inhibiting IL-8 and MMP-3 expression in human triple-negative breast cancer cells
Q39719008c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression
Q36286056c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases.

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