Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules.

scientific article

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/MMI.12045
P932PMC publication ID3508296
P698PubMed publication ID23095033
P5875ResearchGate publication ID232698475

P50authorTara J MoriartyQ61968993
P2093author name stringJing Wu
Hong Zhou
Rhodaba Ebady
Yi-Pin Lin
George Chaconas
Pierre-Olivier Hardy
Eric H Weening
Paul Kubes
Meiqing Shi
Jon T Skare
John Leong
Tanya Odisho
Aydan Salman-Dilgimen
P2860cites workCrystal structure of a heparin- and integrin-binding segment of human fibronectin.Q22009026
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferiQ22122357
The emergence of Lyme diseaseQ22241895
Epidemiology and diagnosis of Lyme borreliosisQ22248045
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living hostQ27318431
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living hostQ27318574
Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmissionQ27347529
Structural and Functional Analysis of the Tandem  -Zipper Interaction of a Streptococcal Protein with Human FibronectinQ27671736
A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferiQ28144621
BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand bindingQ28902813
Lyme borreliosisQ29013670
Getting to the site of inflammation: the leukocyte adhesion cascade updatedQ29547271
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.Q30355212
Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticksQ30492103
The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissueQ30505529
Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritisQ33356344
Identification of loci critical for replication and compatibility of a Borrelia burgdorferi cp32 plasmid and use of a cp32-based shuttle vector for the expression of fluorescent reporters in the Lyme disease spirochaeteQ59505762
Inactivation of the fibronectin-binding adhesin genebbk32significantly attenuates the infectivity potential ofBorrelia burgdorferiQ62966001
Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen.Q64899924
Heparin binding is necessary, but not sufficient, for fibronectin aggregation. A fluorescence polarization studyQ70111626
Structural features of fibronectin synthetic peptide FN-C/H II, responsible for cell adhesion, neurite extension, and heparan sulfate bindingQ72854733
Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell bindingQ73042813
The tandem beta-zipper model defines high affinity fibronectin-binding repeats within Staphylococcus aureus FnBPAQ80557383
The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differs from other pathogensQ80832075
Identification of the determinant conferring permissive substrate usage in the telomere resolvase, ResTQ33475522
The multifunctional Staphylococcus aureus autolysin aaa mediates adherence to immobilized fibrinogen and fibronectinQ33946932
Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1.Q34005702
Mapping the ligand-binding region of Borrelia burgdorferi fibronectin-binding protein BBK32.Q34008131
Borrelia burgdorferi RevA antigen is a surface-exposed outer membrane protein whose expression is regulated in response to environmental temperature and pHQ34008806
Fibronectin at a glanceQ34150530
Isolation and cultivation of Lyme disease spirochetesQ34258685
Bgp, a secreted glycosaminoglycan-binding protein of Borrelia burgdorferi strain N40, displays nucleosidase activity and is not essential for infection of immunodeficient miceQ34601829
Borrelia burgdorferi lacking BBK32, a fibronectin-binding protein, retains full pathogenicityQ34681119
Invasion of eukaryotic cells by Borrelia burgdorferi requires β(1) integrins and Src kinase activityQ34739867
High-affinity interaction between fibronectin and the group B streptococcal C5a peptidase is unaffected by a naturally occurring four-amino-acid deletion that eliminates peptidase activityQ35073955
Analysis of Borrelia burgdorferi Surface Proteins as Determinants in Establishing Host Cell InteractionsQ35086019
Differential telomere processing by Borrelia telomere resolvases in vitro but not in vivoQ35130167
Allelic variation of the Lyme disease spirochete adhesin DbpA influences spirochetal binding to decorin, dermatan sulfate, and mammalian cellsQ35191997
Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivityQ35242498
The molecular basis of fibronectin-mediated bacterial adherence to host cellsQ35752937
Essential role for OspA/B in the life cycle of the Lyme disease spirocheteQ36403858
Complement evasion of pathogens: common strategies are shared by diverse organismsQ36927858
Borrelia burgdorferi RevA antigen binds host fibronectinQ37256541
Mechanochemistry of receptor-ligand bonds.Q37373858
Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteinsQ37778852
Adhesion mechanisms of Borrelia burgdorferi.Q37873834
Replacing a lectin domain residue in L-selectin enhances binding to P-selectin glycoprotein ligand-1 but not to 6-sulfo-sialyl Lewis xQ38293878
Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferiQ38314563
Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin.Q38315553
Interaction of heparin with fibronectin and isolated fibronectin domainsQ38337761
Epidemiology and clinical similarities of human spirochetal diseasesQ38717737
The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV.Q39656200
Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycansQ40337641
Borrelia burgdorferi binds fibronectin through a tandem beta-zipper, a common mechanism of fibronectin binding in staphylococci, streptococci, and spirochetesQ42649010
A novel fibronectin binding motif in MSCRAMMs targets F3 modulesQ43142871
The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectinQ43234542
Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responsesQ46806608
Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31.Q47988454
Electrotransformation of the spirochete Borrelia burgdorferiQ49730404
Sequential Peptide Affinity (SPA) system for the identification of mammalian and bacterial protein complexes.Q54503035
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmacromoleculeQ178593
P304page(s)1116-1131
P577publication date2012-10-24
P1433published inMolecular MicrobiologyQ6895967
P1476titleVascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules
P478volume86

Reverse relations

cites work (P2860)
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Q35947418Borrelia burgdorferi RevA Significantly Affects Pathogenicity and Host Response in the Mouse Model of Lyme Disease
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Q91725406Borrelia burgdorferi bbk13 Is Critical for Spirochete Population Expansion in the Skin during Early Infection
Q47370006Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme disease
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