| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2013PNAS..110E1361R |
| P356 | DOI | 10.1073/PNAS.1220723110 |
| P932 | PMC publication ID | 3625291 |
| P698 | PubMed publication ID | 23515331 |
| P50 | author | Michael Sheetz | Q1929376 |
| Nils C Gauthier | Q96038090 | ||
| Nicolas Biais | Q124153854 | ||
| P2093 | author name string | Pere Roca-Cusachs | |
| Eileen Puklin-Faucher | |||
| Armando del Rio | |||
| P2860 | cites work | Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers | Q24292129 |
| Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis | Q24294897 | ||
| Phosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migration | Q24295196 | ||
| Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C | Q24300550 | ||
| Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function | Q24306891 | ||
| An interaction between alpha-actinin and the beta 1 integrin subunit in vitro | Q24317203 | ||
| Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion | Q24318468 | ||
| Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin | Q24322742 | ||
| Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism | Q24679102 | ||
| Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading | Q27438144 | ||
| Integrins: bidirectional, allosteric signaling machines | Q27860700 | ||
| Tensional homeostasis and the malignant phenotype | Q27860932 | ||
| Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain | Q28298484 | ||
| Vitronectin and its receptors | Q28298613 | ||
| Nanoscale architecture of integrin-based cell adhesions | Q28299215 | ||
| Green fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding | Q28343605 | ||
| α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts | Q28476091 | ||
| Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin | Q28478502 | ||
| Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin | Q28505684 | ||
| Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging | Q28587454 | ||
| Kindlin-3 is essential for integrin activation and platelet aggregation | Q28595084 | ||
| A guided tour into subcellular colocalization analysis in light microscopy | Q29547199 | ||
| Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner | Q29616027 | ||
| Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates | Q29616030 | ||
| Stretching single talin rod molecules activates vinculin binding | Q29617762 | ||
| Investigating complexity of protein-protein interactions in focal adhesions | Q30438896 | ||
| Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells | Q30442995 | ||
| Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow | Q30478216 | ||
| Talin depletion reveals independence of initial cell spreading from integrin activation and traction | Q30490335 | ||
| Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction | Q30490566 | ||
| Cytoskeletal coherence requires myosin-IIA contractility | Q30492983 | ||
| Cells test substrate rigidity by local contractions on submicrometer pillars. | Q30513202 | ||
| Force mapping in epithelial cell migration | Q30856290 | ||
| Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation | Q31018295 | ||
| Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. | Q31044872 | ||
| The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation | Q33874977 | ||
| Differential transmission of actin motion within focal adhesions | Q34598084 | ||
| Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2 | Q36097610 | ||
| Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling | Q36117214 | ||
| The relationship between force and focal complex development | Q36323790 | ||
| Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin | Q36328433 | ||
| Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin | Q36530111 | ||
| An interaction between zyxin and alpha-actinin | Q36531106 | ||
| Integrin cytoskeletal interactions. | Q36909794 | ||
| α-Actinin: a direct link between actin and integrins | Q36974800 | ||
| Mechanotransduction gone awry | Q37158222 | ||
| Alpha-actinin structure and regulation | Q37167269 | ||
| Integrin signalling at a glance | Q37271581 | ||
| Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails | Q37360853 | ||
| Force propagation across cells: mechanical coherence of dynamic cytoskeletons | Q37390089 | ||
| Mechanical control of tissue and organ development | Q37730278 | ||
| Finding the weakest link: exploring integrin-mediated mechanical molecular pathways | Q38026498 | ||
| Phosphoinositide binding to the substrate regulates susceptibility to proteolysis by calpain. | Q39260815 | ||
| The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells | Q40358354 | ||
| Periodic lamellipodial contractions correlate with rearward actin waves | Q40579490 | ||
| Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets | Q40868085 | ||
| Identification of the vinculin-binding site in the cytoskeletal protein alpha-actinin | Q42157673 | ||
| Trimers of the fibronectin cell adhesion domain localize to actin filament bundles and undergo rearward translocation. | Q42814435 | ||
| The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase | Q43615477 | ||
| Phosphoinositide binding inhibits alpha-actinin bundling activity. | Q44418934 | ||
| Identification of the beta1-integrin binding site on alpha-actinin by cryoelectron microscopy | Q45274770 | ||
| The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins | Q46828504 | ||
| Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts | Q58022582 | ||
| Specific interaction of vinculin with alpha-actinin | Q70353415 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | extracellular matrix | Q193825 |
| P304 | page(s) | E1361-70 | |
| P577 | publication date | 2013-03-20 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation | |
| P478 | volume | 110 |
| Q38977036 | A proteomics view on integrin-mediated adhesions |
| Q41238998 | Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment. |
| Q38164987 | Advances in magnetic tweezers for single molecule and cell biophysics. |
| Q38261549 | Advances in techniques for probing mechanoregulation of tissue morphogenesis |
| Q48133926 | Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ |
| Q58058687 | An inspection of force reduction in high force electromagnetic tweezers made of FeCo-V foil by laser cutting |
| Q48061262 | Appreciating force and shape—the rise of mechanotransduction in cell biology |
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| Q37107142 | Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes |
| Q47098047 | Cell shape information is transduced through tension-independent mechanisms. |
| Q90351944 | Cellular Mechanotransduction: From Tension to Function |
| Q38896354 | Cellular chirality arising from the self-organization of the actin cytoskeleton. |
| Q96136234 | Cellular contractile forces are nonmechanosensitive |
| Q58058692 | Characterization of the mechanical properties of HL-1 cardiomyocytes with high throughput magnetic tweezers |
| Q47294328 | Computational modeling of single-cell mechanics and cytoskeletal mechanobiology. |
| Q33411778 | Congenital platelet disorders and understanding of platelet function |
| Q30834256 | Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates |
| Q27313331 | Control of cell-cell forces and collective cell dynamics by the intercellular adhesome |
| Q34127549 | Direct observation of α-actinin tension and recruitment at focal adhesions during contact growth |
| Q27342751 | Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice |
| Q42858444 | Distinct focal adhesion protein modules control different aspects of mechanotransduction |
| Q36753948 | Dynamic Regulation of α-Actinin's Calponin Homology Domains on F-Actin |
| Q38796960 | Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro. |
| Q37473452 | FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration |
| Q91334253 | Filopodia and focal adhesions: An integrated system driving branching morphogenesis in neuronal pathfinding and angiogenesis |
| Q47969134 | Focal adhesions: a personal perspective on a half century of progress |
| Q34315046 | Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate |
| Q47277135 | Force loading explains spatial sensing of ligands by cells |
| Q33647687 | Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues. |
| Q47799259 | Influence of past injurious exercise on fiber type-specific acute anabolic response to resistance exercise in skeletal muscle. |
| Q92409326 | Innovative Tools for Mechanobiology: Unraveling Outside-In and Inside-Out Mechanotransduction |
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| Q30371366 | Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions |
| Q39016068 | Integrin-mediated mechanotransduction |
| Q49805162 | Integrins Were Involved in Soybean Agglutinin Induced Cell Apoptosis in IPEC-J2. |
| Q92643473 | Integrins as biomechanical sensors of the microenvironment |
| Q91743168 | Integrins: Moonlighting Proteins in Invadosome Formation |
| Q38423864 | Intracellular signaling of cardiac fibroblasts |
| Q43463526 | Job-splitting among integrins |
| Q92020137 | Kindlin Is Mechanosensitive: Force-Induced Conformational Switch Mediates Cross-Talk among Integrins |
| Q33726992 | Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer |
| Q30559231 | Matrix identity and tractional forces influence indirect cardiac reprogramming |
| Q27348613 | Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractions |
| Q37670791 | Mechanical Stress Regulates Osteogenesis and Adipogenesis of Rat Mesenchymal Stem Cells through PI3K/Akt/GSK-3β/β-Catenin Signaling Pathway |
| Q45069366 | Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of Xenopus mesendoderm tissue at gastrulation |
| Q33922295 | Mechanical checkpoint for persistent cell polarization in adhesion-naive fibroblasts |
| Q48043368 | Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. |
| Q33692515 | Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells |
| Q63408491 | Mechanisms and impact of altered tumour mechanics |
| Q38124627 | Mechanisms of talin-dependent integrin signaling and crosstalk |
| Q38619878 | Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome |
| Q35901064 | Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2. |
| Q35682348 | Mechanotransduction: use the force(s). |
| Q94140760 | Microtechnologies for Cell Microenvironment Control and Monitoring |
| Q38737459 | Mitochondrial DNA 3243A>G heteroplasmy is associated with changes in cytoskeletal protein expression and cell mechanics. |
| Q38915438 | Myoferlin depletion elevates focal adhesion kinase and paxillin phosphorylation and enhances cell-matrix adhesion in breast cancer cells. |
| Q57818449 | NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion |
| Q30590254 | Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission |
| Q48041707 | Nanopillar force measurements reveal actin-cap-mediated YAP mechanotransduction |
| Q38872068 | Non-monotonic cellular responses to heterogeneity in talin protein expression-level. |
| Q57839076 | Osteogenic differentiation on DLC-PDMS-h surface |
| Q30360988 | PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility. |
| Q54950005 | Past injurious exercise attenuates activation of primary calcium-dependent injury pathways in skeletal muscle during subsequent exercise. |
| Q47073677 | Paxillin genes and actomyosin contractility regulate myotome morphogenesis in zebrafish. |
| Q27342564 | Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement |
| Q95271962 | Phagocytic Integrins: Activation and Signaling |
| Q36017626 | Physical and functional interactions between a glioma cation channel and integrin-β1 require α-actinin |
| Q30656470 | Physical principles of membrane remodelling during cell mechanoadaptation |
| Q38182363 | Protein conformation as a regulator of cell-matrix adhesion |
| Q37735359 | Rear actomyosin contractility-driven directional cell migration in three-dimensional matrices: a mechano-chemical coupling mechanism |
| Q36264774 | Regulation of integrin-mediated adhesions. |
| Q30578644 | Rigidity sensing and adaptation through regulation of integrin types. |
| Q38747970 | Role of vinculin in cellular mechanotransduction |
| Q30405644 | Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility |
| Q27310707 | Spatiotemporal dynamics of traction forces show three contraction centers in migratory neurons |
| Q58592367 | Steps in Mechanotransduction Pathways that Control Cell Morphology |
| Q38883082 | Stiffening and unfolding of early deposited-fibronectin increase proangiogenic factor secretion by breast cancer-associated stromal cells |
| Q30667566 | Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility |
| Q30855022 | Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4. |
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| Q92453682 | Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway |
| Q30008827 | TCR Triggering Induces the Formation of Lck-RACK1-Actinin-1 Multiprotein Network Affecting Lck Redistribution |
| Q33978054 | Talins and kindlins: partners in integrin-mediated adhesion. |
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| Q27304782 | The F-actin bundler α-actinin Ain1 is tailored for ring assembly and constriction during cytokinesis in fission yeast |
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