Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.

scientific article

Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NBT.2465
P932PMC publication ID3775583
P698PubMed publication ID23242162

P50authorEduardo MarbánQ56393799
P2093author name stringWenbin Liang
Hee Cheol Cho
Nidhi Kapoor
P2860cites workAmplitude distribution of calcium sparks in confocal images: theory and studies with an automatic detection methodQ24537284
Direct conversion of fibroblasts to functional neurons by defined factorsQ24641912
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atriaQ24681355
Dedifferentiation and Proliferation of Mammalian CardiomyocytesQ27320581
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Induction of pluripotent stem cells from adult human fibroblasts by defined factorsQ27860967
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Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overloadQ28285683
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Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking developmentQ28506813
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesisQ28510707
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factorsQ28589872
Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3Q28594589
Active genes are tri-methylated at K4 of histone H3Q29547668
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytesQ29620599
A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.Q33722486
The role of the funny current in pacemaker activity.Q34099619
Direct conversion of human fibroblasts to multilineage blood progenitors.Q34148584
Biological pacemaker created by gene transferQ34149202
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.Q34290920
Transcriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytesQ34800053
Developmental changes in beta-adrenergic and cholinergic interactions on calcium-dependent slow action potentials in rat ventricular musclesQ35887811
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Genesis and regulation of the heart automaticity.Q37216067
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.Q37222054
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Development of the pacemaker tissues of the heart.Q37687712
Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices?Q37702697
Gene transfer of a synthetic pacemaker channel into the heart: a novel strategy for biological pacingQ40222088
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells.Q40479961
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.Q41067008
A myocardial lineage derives from Tbx18 epicardial cellsQ41213731
HCN212-channel biological pacemakers manifesting ventricular tachyarrhythmias are responsive to treatment with I(f) blockadeQ41875995
High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cellsQ42489642
Ectopic expression of Nkx2.5 suppresses the formation of the sinoatrial node in miceQ42840235
Cardiomyocyte cell cycle control and growth estimation in vivo--an analysis based on cardiomyocyte nucleiQ43195307
Sinoatrial nodal cell ryanodine receptor and Na(+)-Ca(2+) exchanger: molecular partners in pacemaker regulationQ43649137
Expression and function of a biological pacemaker in canine heartQ44342373
Voltage clamp measurements of the hyperpolarization-activated inward current I(f) in single cells from rabbit sino-atrial nodeQ44601829
Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakersQ45196010
Calcium cycling protein density and functional importance to automaticity of isolated sinoatrial nodal cells are independent of cell sizeQ47286609
Correlation between electrical activity and the size of rabbit sino-atrial node cellsQ47322505
Tbx18 and the fate of epicardial progenitorsQ48000607
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.Q51803470
Computer three-dimensional reconstruction of the sinoatrial node.Q51978382
Alternation of inwardly rectifying background K+ channel during development of rat fetal cardiomyocytes.Q52140737
Allelic imbalance at intragenic markers of Tbx18 is a hallmark of murine osteosarcoma.Q53381339
Atrial natriuretic factor in the vena cava and sinus node.Q53766169
Action potential and membrane currents of single pacemaker cells of the rabbit heartQ54466625
Human Biological PacemakersQ60300780
Functional and morphological organization of the rabbit sinus nodeQ71127555
Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal developmentQ71699187
ELECTRON MICROSCOPIC AND ELECTROPHYSIOLOGIC STUDY OF THE PACEMAKER IN THE SINO-ATRIAL NODE OF THE RABBIT HEARTQ76671477
Creation of a biological pacemaker by cell fusionQ80065630
P4510describes a project that usesImageJQ1659584
P433issue1
P304page(s)54-62
P577publication date2012-12-16
P1433published inNature BiotechnologyQ1893837
P1476titleDirect conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.
P478volume31