| P50 | author | Lance Johnson | Q79714953 |
| | Robert D. Steiner | Q38325378 |
| P2093 | author name string | Jacob Raber | |
| | Nobuyo Maeda | |
| | Louise S Merkens | |
| | Reid H J Olsen | |
| | Patrick M Sullivan | |
| | Andrea DeBarber | |
| P2860 | cites work | Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease | Q22248091 |
| | Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2 | Q24310889 |
| | Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis | Q24608930 |
| | ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling | Q24616113 |
| | ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models | Q24628845 |
| | Role of apolipoprotein E in anxiety | Q24681864 |
| | Functions of lipoprotein receptors in neurons | Q28189448 |
| | Apolipoprotein E: far more than a lipid transport protein | Q28204471 |
| | Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site | Q28264429 |
| | Morris water maze: procedures for assessing spatial and related forms of learning and memory | Q28296351 |
| | A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve | Q28579544 |
| | Isoform-specific binding of apolipoprotein E to beta-amyloid | Q28596589 |
| | Neuropsychiatric associations of apolipoprotein E alleles in subjects with combat-related posttraumatic stress disorder. | Q51985840 |
| | ApoE isoform affects LTP in human targeted replacement mice. | Q51996089 |
| | Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice. | Q52051272 |
| | Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. | Q53321766 |
| | The association between insulin and low-density lipoprotein receptors. | Q53676952 |
| | The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments | Q70169929 |
| | Extrahepatic synthesis of apolipoprotein E | Q70767412 |
| | Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform | Q73186590 |
| | Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis | Q73500603 |
| | APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis | Q73905009 |
| | Association of the low-density lipoprotein receptor gene with obesity in Native American populations | Q74067058 |
| | Apolipoprotein E polymorphism--a risk factor for metabolic syndrome | Q81233537 |
| | Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants | Q83946316 |
| | Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery | Q29615235 |
| | Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance | Q30274556 |
| | Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes | Q30274560 |
| | Apo E structure determines VLDL clearance and atherosclerosis risk in mice. | Q30322098 |
| | LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease | Q33521909 |
| | Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females | Q33563135 |
| | Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice | Q33585519 |
| | Object recognition memory and the rodent hippocampus | Q33593321 |
| | Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model | Q33960315 |
| | Neurobiology of Pavlovian fear conditioning. | Q34088053 |
| | The vascular contribution to Alzheimer's disease | Q34178526 |
| | Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala | Q34361405 |
| | Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4 | Q34378904 |
| | Apolipoprotein E: From lipid transport to neurobiology | Q34497951 |
| | Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system | Q34559847 |
| | Reelin, lipoprotein receptors and synaptic plasticity | Q34575575 |
| | Structure and physiologic function of the low-density lipoprotein receptor | Q34650688 |
| | Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study | Q34655640 |
| | Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis | Q35152236 |
| | Functional interaction between APOE4 and LDL receptor isoforms in Alzheimer's disease | Q35447761 |
| | ApoE genotype accounts for the vast majority of AD risk and AD pathology | Q35789660 |
| | Impairments in spatial memory retention of GFAP-apoE4 female mice | Q35945895 |
| | Dementia and diabetes mellitus: association with apolipoprotein e4 polymorphism from a hospital in southern India. | Q36021657 |
| | Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice | Q36206696 |
| | Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis. | Q36279902 |
| | Apolipoprotein E isoform-specific binding to the low-density lipoprotein receptor | Q36327871 |
| | Expression profiling in APP23 mouse brain: inhibition of Abeta amyloidosis and inflammation in response to LXR agonist treatment | Q36407043 |
| | Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease | Q36613756 |
| | Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples | Q36635968 |
| | Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation | Q36658372 |
| | Liver X receptor-mediated gene regulation and cholesterol homeostasis in brain: relevance to Alzheimer's disease therapeutics | Q36789918 |
| | ApoE isoform-dependent deficits in extinction of contextual fear conditioning | Q36811758 |
| | Cortisol and post-traumatic stress disorder in adults: systematic review and meta-analysis | Q36989327 |
| | The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction | Q37166455 |
| | Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E. | Q37497056 |
| | Apolipoprotein E synthesis in human kidney, adrenal gland, and liver | Q37601028 |
| | Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner | Q37612769 |
| | Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets | Q37672903 |
| | Brain cholesterol in normal and pathological aging | Q37722863 |
| | Proposed mechanism for lipoprotein remodelling in the brain. | Q37752606 |
| | The link between altered cholesterol metabolism and Alzheimer's disease. | Q38023563 |
| | Apolipoprotein E gene polymorphism, alcohol use, and their interactions in combat-related posttraumatic stress disorder | Q39403290 |
| | Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts | Q40224633 |
| | Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis | Q40374258 |
| | The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor | Q40428631 |
| | Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides | Q40879124 |
| | Differential neurotrophic effects of apolipoprotein E in aged transgenic mice | Q41664893 |
| | Hippocampal lesions disrupt an associative mismatch process. | Q41712827 |
| | Apolipoprotein E and cognitive performance | Q41727967 |
| | Human LDL receptor enhances sequestration of ApoE4 and VLDL remnants on the surface of hepatocytes but not their internalization in mice | Q42327899 |
| | Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology | Q42655700 |
| | Behavioural and pharmacological characterisation of the elevated "zero-maze" as an animal model of anxiety. | Q42690200 |
| | Presence of the APOE epsilon4 allele modifies the relationship between type 2 diabetes and cognitive performance: the Maine-Syracuse Study | Q43289323 |
| | Apolipoprotein E polymorphism and lipid levels differ by gender and family history of diabetes: the Rancho Bernardo Study | Q43734715 |
| | Potential genetic markers of sporadic Alzheimer's dementia | Q43794827 |
| | LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice | Q43819543 |
| | Apolipoprotein isoform E4 does not increase coronary heart disease risk in carriers of low-density lipoprotein receptor mutations | Q43833684 |
| | Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study | Q43935519 |
| | Effect of domain interaction on apolipoprotein E levels in mouse brain. | Q44267254 |
| | Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. | Q44582249 |
| | Reduced levels of human apoE4 protein in an animal model of cognitive impairment | Q44601281 |
| | Obesity and alcohol modulate the effect of apolipoprotein E polymorphism on lipids and insulin | Q44625319 |
| | Obesity modulates the association among APOE genotype, insulin, and glucose in men. | Q44705316 |
| | Frequency and Characteristics of Anxiety Among Patients With Alzheimer's Disease and Related Dementias | Q45067649 |
| | Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor | Q45079596 |
| | Genetic association of low density lipoprotein receptor and Alzheimer's disease | Q45178116 |
| | apoE isoforms and measures of anxiety in probable AD patients and Apoe-/- mice | Q45263104 |
| | Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels | Q46262337 |
| | Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. | Q46384417 |
| | Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice | Q46405880 |
| | Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus | Q47320273 |
| | Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice | Q47938732 |
| | Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent | Q48087117 |
| | Isoform-specific effects of apolipoprotein E on cognitive performance in targeted-replacement mice overexpressing human APP. | Q48382566 |
| | Genotype-related differences of hippocampal apolipoprotein E levels only in early stages of neuropathological changes in Alzheimer's disease | Q48468827 |
| | Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior | Q48493843 |
| | Severe learning deficits in apolipoprotein E-knockout mice in a water maze task. | Q48759623 |
| | ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42. | Q49149877 |
| | Anxiety affects cognition differently in healthy apolipoprotein E ε4 homozygotes and non-carriers. | Q50608039 |
| | Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis. | Q51867743 |
| P921 | main subject | apolipoproteins E | Q424728 |
| | Low density lipoprotein receptor | Q425649 |
| | spatial memory | Q3560550 |
| | Low density lipoprotein receptor | Q14872730 |
| | regulation of behavioral fear response | Q22301002 |
| P304 | page(s) | 150-162 | |
| P577 | publication date | 2014-01-09 | |
| P1433 | published in | Neurobiology of Disease | Q15716606 |
| P1476 | title | Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner | |
| P478 | volume | 64 | |