Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current.

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Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111E2281D
P356DOI10.1073/PNAS.1407133111
P932PMC publication ID4050574
P698PubMed publication ID24843134
P5875ResearchGate publication ID262536733

P50authorBertil HilleQ202480
Eamonn J DicksonQ57746640
Jill B JensenQ79291228
P2860cites workFAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)PQ24337930
A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBPQ24339494
Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulumQ24529995
Phosphoinositides: tiny lipids with giant impact on cell regulationQ27012953
Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase functionQ27660521
Phosphoinositides in cell regulation and membrane dynamicsQ27861051
Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipidsQ27931171
SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatasesQ27934132
Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domainsQ27934605
ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphologyQ27936693
Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sitesQ27937449
Growth control of Golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinaseQ27940008
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identityQ28118990
ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complexQ28137865
A novel family of phosphatidylinositol 4-kinases conserved from yeast to humansQ28204394
Nuclear localization of phosphatidylinositol 4-kinase betaQ28214594
Phosphatidylinositol 4-kinases: old enzymes with emerging functionsQ28247845
Cloning, expression, and localization of 230-kDa phosphatidylinositol 4-kinaseQ28281559
Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinasesQ28301255
Subcellular locations of phosphatidylinositol 4-kinase isoformsQ28678847
PIP2 signaling in lipid domains: a critical re-evaluationQ30475951
Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganizationQ30515754
Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in DrosophilaQ30521489
Kinetic analysis of receptor-activated phosphoinositide turnoverQ30938703
Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cellsQ33615029
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.Q33913973
Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signalingQ33929518
Modulation of High-Voltage Activated Ca2+ Channels by Membrane Phosphatidylinositol 4,5-BisphosphateQ34099484
Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartmentsQ34121202
A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipidsQ34210092
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptorQ34214128
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the GolgiQ34221739
Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its PlaceQ34264164
The role of phosphoinositides in membrane transportQ34309086
Feedback regulation of receptor-induced Ca2+ signaling mediated by E-Syt1 and Nir2 at endoplasmic reticulum-plasma membrane junctionsQ34382037
Combined Phosphoinositide and Ca2+ Signals Mediating Receptor Specificity toward Neuronal Ca2+ ChannelsQ34452803
Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptorQ34489231
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90Q34752697
Phosphoinositide phosphatases and diseaseQ34877679
Ci-VSP is a depolarization-activated phosphatidylinositol-4,5-bisphosphate and phosphatidylinositol-3,4,5-trisphosphate 5'-phosphataseQ34891762
Junctional signaling microdomains: bridging the gap between the neuronal cell surface and Ca2+ storesQ35017700
A homogeneous and nonisotopic assay for phosphatidylinositol 4-kinasesQ35127738
Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophagesQ35211011
A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranesQ35607232
An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells.Q36255652
Molecular brightness analysis reveals phosphatidylinositol 4-Kinase IIβ association with clathrin-coated vesicles in living cellsQ36330240
Segregation of PIP2 and PIP3 into distinct nanoscale regions within the plasma membraneQ36425688
Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalphaQ36438800
Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.Q36492075
Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling.Q36804632
Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signalingQ36804642
PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identityQ36822749
Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sortingQ37086712
PIP2 is a necessary cofactor for ion channel function: how and why?Q37197976
A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling techniqueQ37224281
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).Q37292741
Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.Q37608552
Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks.Q38100883
Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channelsQ40228821
Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cellsQ41056247
Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cellsQ42509322
AKAP79/150 signal complexes in G-protein modulation of neuronal ion channelsQ42756534
Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesisQ44092262
Interaction of neuronal calcium sensor-1 and ADP-ribosylation factor 1 allows bidirectional control of phosphatidylinositol 4-kinase beta and trans-Golgi network-plasma membrane trafficQ44213173
Probing the regulation of TASK potassium channels by PI4,5P₂ with switchable phosphoinositide phosphatases.Q44346271
PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currentsQ44386912
Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.Q46412703
Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIbeta.Q46957651
Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinasesQ49054230
Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p.Q50797844
Kinetic analysis of guanosine 5'-O-(3-thiotriphosphate) effects on phosphatidylinositol turnover in NRK cell homogenates.Q52605778
P4510describes a project that usesImageJQ1659584
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)E2281-90
P577publication date2014-05-19
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleGolgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current
P478volume111

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