Dynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics

scientific article

Dynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M114.553883
P8608Fatcat IDrelease_fmrhnxbmb5gj5le3nkvzyj7mde
P932PMC publication ID4148866
P698PubMed publication ID25031323

P50authorGraham D WrightQ55245086
Ai Mei ChouQ59683369
P2093author name stringSohail Ahmed
Thankiah Sudhaharan
Kai Ping Sem
P2860cites workIdentification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complexQ22010165
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane rufflingQ24290667
Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actinQ24290738
Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complexQ24291871
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasivenessQ24300415
Direct dynamin-actin interactions regulate the actin cytoskeletonQ24302210
Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structuresQ24312800
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASPQ24318478
The Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamicsQ24336730
CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASPQ24337450
Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53Q24557455
Let's go bananas: revisiting the endocytic BAR codeQ24635636
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteinsQ24678535
Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosisQ24684143
A feedback loop between dynamin and actin recruitment during clathrin-mediated endocytosisQ27319900
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)Q27330089
BAR domains as sensors of membrane curvature: the amphiphysin BAR structureQ27642663
Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2Q28144520
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexQ28505970
Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shapeQ28510777
Differential distribution of dynamin isoforms in mammalian cellsQ28564633
Modulation of Rac localization and function by dynaminQ28566981
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assemblyQ28609843
Dynasore, a cell-permeable inhibitor of dynaminQ29619881
Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminalsQ29620183
I-BAR domains, IRSp53 and filopodium formationQ30157055
The Toca-1-N-WASP complex links filopodial formation to endocytosisQ30157367
Amphiphysin I antisense oligonucleotides inhibit neurite outgrowth in cultured hippocampal neurons.Q30176317
Dynamin2 and cortactin regulate actin assembly and filament organization.Q30310193
Regulating actin dynamics at membranes: a focus on dynaminQ30433704
Dynamin2 GTPase and cortactin remodel actin filamentsQ30434848
Dynamin participates in focal extracellular matrix degradation by invasive cellsQ30477655
A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cellsQ30477658
Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closureQ30482461
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pitsQ30494265
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
Tracking retrograde flow in keratocytes: news from the frontQ30856501
Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complexQ34334221
Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.Q34610666
Cadherin-dependent filopodia control preimplantation embryo compactionQ35052017
The role of dynamin in the assembly and function of podosomes and invadopodiaQ35672887
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formationQ35763102
Role of fascin in filopodial protrusionQ36118593
Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retractionQ36316633
Dynamin, a membrane-remodelling GTPaseQ36460251
Filopodia: the fingers that do the walkingQ36915801
Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosisQ37486482
Molecular mechanisms of membrane deformation by I-BAR domain proteins.Q39894096
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Self-assembly of filopodia-like structures on supported lipid bilayersQ42360649
Filopodia: the cellular quills of hedgehog signaling?Q46593376
Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis.Q52679816
I-BAR domain proteins: linking actin and plasma membrane dynamicsQ82533830
P4510describes a project that usesImageJQ1659584
P433issue35
P407language of work or nameEnglishQ1860
P304page(s)24383-24396
P577publication date2014-07-16
P1433published inJournal of Biological ChemistryQ867727
P1476titleDynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics
P478volume289

Reverse relations

cites work (P2860)
Q93231136BAR domain proteins-a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton
Q39153850Deciphering the BAR code of membrane modulators.
Q37529495Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes
Q51631984Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation.
Q39026776Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State.
Q97522672IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules
Q26798113IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders
Q99562086Molecular architecture of postsynaptic Interactomes
Q97520122Palmitoylated Proteins in Dendritic Spine Remodeling
Q37571307Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development
Q64121943Superresolution microscopy reveals distinct localisation of full length IRSp53 and its I-BAR domain protein within filopodia

Search more.