Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

scientific article

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.3132
P932PMC publication ID4406851
P698PubMed publication ID25822250
P5875ResearchGate publication ID274262677

P50authorAna Fernández-SesmaQ37368173
Luis Martinez-GilQ38545074
Sven HeinzQ39512651
Christopher F BaslerQ54188848
Matthew S MillerQ55762182
Ivan MarazziQ56401570
Jessica Sook Yuin HoQ56863034
Alexander RialdiQ56863035
Ana M MaestreQ79231419
Chris BennerQ79949523
Harm van BakelQ30089951
P2093author name stringMartin F Lavin
Olivier J Becherel
Joaquín Madrenas
John A T Young
Camilla Melegari
Justine Noel
Panagiotis Mitsopoulos
Alicia R Feagins
Zuleyma Peralta
Micah Tilove
Natasha P Moshkina
P2860cites workUltrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
Suppression of the antiviral response by an influenza histone mimicQ24307599
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent terminationQ24307617
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damageQ24309516
Peroxisomes are signaling platforms for antiviral innate immunityQ24310723
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)Q24533845
A scaling normalization method for differential expression analysis of RNA-seq dataQ24628783
c-Myc regulates transcriptional pause releaseQ24629119
Clinical and molecular phenotype of Aicardi-Goutieres syndromeQ24655458
Transcriptional control of the inflammatory responseQ37622051
Inducible gene expression: diverse regulatory mechanismsQ37737546
Unravelling the means to an end: RNA polymerase II transcription termination.Q37864536
Emerging roles for chromatin as a signal integration and storage platformQ38092575
The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryoQ42046257
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodelingQ42252373
Kinetic competition between RNA Polymerase II and Sen1-dependent transcription terminationQ42276193
A TAF4 coactivator function for E proteins that involves enhanced TFIID bindingQ42280074
A movie of RNA polymerase II transcriptionQ48424870
Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genesQ57634686
TopHat: discovering splice junctions with RNA-SeqQ24655505
A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcriptionQ27645941
Suppression of inflammation by a synthetic histone mimicQ27665789
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeastQ27930332
Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.Q27934234
Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicaseQ27938434
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promotersQ28302903
Progression through the RNA polymerase II CTD cycleQ29614782
Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4FQ29620295
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage responseQ30532840
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's diseaseQ33292417
Transcriptional regulation and its misregulation in disease.Q34036033
R-loop formation is a distinctive characteristic of unmethylated human CpG island promotersQ34258378
Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2.Q34295566
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infectionQ34548112
Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencingQ34672035
Type 1 interferons and the virus-host relationship: a lesson in détente .Q36475884
New approaches to the study of sepsisQ36492375
H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activationQ36657584
Triggering the innate antiviral response through IRF-3 activationQ36774934
Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rhoQ36841147
The long unwinding road of RNA helicasesQ36902461
Global regulation of promoter melting in naive lymphocytesQ36935665
Innate recognition of virusesQ36950601
Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivoQ37068274
A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infectionQ37148404
Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signalsQ37352913
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)485-494
P577publication date2015-03-30
P1433published inNature ImmunologyQ1071725
P1476titleSenataxin suppresses the antiviral transcriptional response and controls viral biogenesis
P478volume16

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cites work (P2860)
Q36089379A new model to study neurodegeneration in ataxia oculomotor apraxia type 2
Q58569508Acute microglia ablation induces neurodegeneration in the somatosensory system
Q49565575Chromatin dependencies in cancer and inflammation.
Q39641817Deep Genetic Connection Between Cancer and Developmental Disorders
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Q58697022Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation
Q91106542Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS
Q47803583PIKKing a way to regulate inflammation
Q36882769Senataxin controls meiotic silencing through ATR activation and chromatin remodeling.
Q92967078Signatures of adaptive divergence among populations of an avian species of conservation concern
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Q37540505Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
Q36082634XRN2 Links Transcription Termination to DNA Damage and Replication Stress

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