Mechanism of NMDA Receptor Inhibition and Activation

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Mechanism of NMDA Receptor Inhibition and Activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELL.2016.03.028
P932PMC publication ID4914038
P698PubMed publication ID27062927

P2093author name stringCraig Yoshioka
Eric Gouaux
Hassane S Mchaourab
Richard A Stein
Shujia Zhu
Chia-Hsueh Lee
April Goehring
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Structural Insights into Competitive Antagonism in NMDA ReceptorsQ27681450
Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptorsQ41051191
Heteromerization of ligand binding domains of N-methyl-D-aspartate receptor requires both coagonists, L-glutamate and glycineQ41786510
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypesQ42871027
Zinc dynamics and action at excitatory synapses.Q48726808
3H5,7-Dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sitesQ48793316
A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.Q48829389
Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro.Q48946347
Kinetics of NMDA channel opening.Q52200923
Glycine potentiates the NMDA response in cultured mouse brain neuronsQ59050531
Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domainQ86251831
Crystal structure of a heterotetrameric NMDA receptor ion channelQ27684006
NMDA receptor structures reveal subunit arrangement and pore architectureQ27684638
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
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Heteromeric NMDA receptors: molecular and functional distinction of subtypesQ28182183
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Magnesium gates glutamate-activated channels in mouse central neuronesQ29616237
Automated electron microscope tomography using robust prediction of specimen movementsQ29616585
Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces.Q30361205
Toward the fourth dimension of membrane protein structure: insight into dynamics from spin-labeling EPR spectroscopyQ30409391
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domainQ30538804
Structural mechanism of glutamate receptor activation and desensitizationQ30593263
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Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neuronesQ34255679
Subunit arrangement and function in NMDA receptorsQ34466595
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptorQ34571210
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and diseaseQ34651972
Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized statesQ34679225
Molecular cloning and characterization of the rat NMDA receptorQ34762781
Single-Particle Cryo-EM at Crystallographic ResolutionQ35537724
Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6Q35646003
Neuroenergetics and the kinetic design of excitatory synapses.Q36302344
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition.Q37184815
Control of NMDA receptor function by the NR2 subunit amino-terminal domainQ37418445
Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyaminesQ38254691
GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunctionQ39112355
Control of proton sensitivity of the NMDA receptor by RNA splicing and polyaminesQ39474796
Mechanism of differential control of NMDA receptor activity by NR2 subunitsQ39858588
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparationsQ39922896
Conformational restriction blocks glutamate receptor desensitizationQ40206387
Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.Q40782999
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)704-714
P577publication date2016-04-06
P1433published inCellQ655814
P1476titleMechanism of NMDA Receptor Inhibition and Activation
P478volume165

Reverse relations

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