Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures

scientific article

Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FGENE.2016.00188
P932PMC publication ID5099244
P698PubMed publication ID27877192

P2093author name stringIgor Akushevich
Svetlana Ukraintseva
Anatoliy I Yashin
Deqing Wu
Irina Kulminskaya
Konstantin G Arbeev
Liubov Arbeeva
Alexander M Kulminski
Arseniy Yashkin
Eric Stallard
Mikhail Kovtun
Ilya Zhbannikov
P2860cites workLipoprotein genotype and conserved pathway for exceptional longevity in humansQ21146060
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Patterns of linkage disequilibrium in different populations: implications and opportunities for lipid-associated loci identified from genome-wide association studiesQ28272153
Failure to Replicate: Sound the AlarmQ28596536
Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only studyQ30494937
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Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevityQ30581631
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Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotypeQ33307072
Failure to replicate a genetic association may provide important clues about genetic architectureQ33463308
Prioritizing GWAS results: A review of statistical methods and recommendations for their applicationQ33571786
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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacyQ34974751
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Nonreplication in genetic studies of complex diseases--lessons learned from studies of osteoporosis and tentative remediesQ36061544
Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variantsQ36494871
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Fine mapping of type 2 diabetes susceptibility lociQ38252712
Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3BQ41838551
Confounding by linkage disequilibriumQ42385487
Linkage disequilibrium measures for fine-scale mapping of disease loci are revisitedQ42921820
Genetic flip-flop without an accompanying change in linkage disequilibriumQ43262246
Linkage disequilibrium patterns of the human genome across populationsQ46420212
Patterns of genetic variation in the hypertension candidate gene GRK4: ethnic variation and haplotype structureQ46914961
Population differences in DNA sequence variation and linkage disequilibrium at the PON1 geneQ47982239
Lack of replication of previous autism spectrum disorder GWAS hits in European populationsQ47982419
A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individualsQ57251795
Lack of Replication of Seven Pancreatic Cancer Susceptibility Loci Identified in Two Asian PopulationsQ57610440
Genes and longevity: lessons from studies of centenariansQ74012412
Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of biasQ74028329
Lack of replication of genetic associations with human longevityQ79946350
Lack of replication of common EXT2 gene variants with susceptibility to type 2 diabetes in Lebanese ArabsQ87122492
P921main subjectgenome-wide association studyQ1098876
P304page(s)188
P577publication date2016-11-08
P1433published inFrontiers in GeneticsQ2499875
P1476titlePure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures
P478volume7

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cites work (P2860)
Q46485851Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort
Q56346087Impact of demography and population dynamics on the genetic architecture of human longevity