Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis

scientific article

Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814
meta-analysisQ815382
systematic reviewQ1504425

External links are
P356DOI10.1093/IJE/DYW074
P932PMC publication ID5100608
P698PubMed publication ID27170764

P50authorGeorge Davey SmithQ21003878
Cesar VictoraQ30348011
Christian Loret de MolaQ56838078
Fernando P HartwigQ88113201
P2093author name stringBernardo Lessa Horta
P2860cites workThe genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expectedQ21091060
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Q21534928
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*Q22066036
Lactase persistence-related genetic variant: population substructure and health outcomesQ24601219
Impact of water intake on energy intake and weight status: a systematic reviewQ24622673
Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasiaQ24669722
Mendelian randomization: genetic anchors for causal inference in epidemiological studiesQ27002487
Primary prevention of coronary heart disease in women through diet and lifestyleQ28140155
Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory elementQ28201340
Identification of a variant associated with adult-type hypolactasiaQ28215372
An upstream polymorphism associated with lactase persistence has increased enhancer activityQ28238875
The genetically programmed down-regulation of lactase in childrenQ28272492
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiologyQ28756441
Fast model-based estimation of ancestry in unrelated individualsQ29614705
Milk intake, height and body mass index in preschool childrenQ30301110
Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysisQ30411394
Molecularly defined lactose malabsorption, peak bone mass and bone turnover rate in young finnish men.Q31111873
European lactase persistence genotype shows evidence of association with increase in body mass indexQ33697667
Lactase non-persistence and milk consumption in EstoniaQ33866496
Correlation of intestinal disaccharidase activities with the C/T-13910 variant and ageQ34098686
Mendelian randomization: prospects, potentials, and limitationsQ34312296
Association of the European lactase persistence variant (LCT-13910 C>T polymorphism) with obesity in the Canary IslandsQ34399618
Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population.Q34431378
Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on healthQ34581653
Lactose intolerance: diagnosis, genetic, and clinical factors.Q34640720
The lactase persistence genotype is a protective factor for the metabolic syndromeQ34669542
Effect of milk tripeptides on blood pressure: a meta-analysis of randomized controlled trialsQ34787114
Chronic non-communicable diseases in Brazil: burden and current challenges.Q50802881
Association between eating patterns and body mass index in a sample of children and adolescents in Northeastern Brazil.Q51102012
The lactase persistence genotype is associated with body mass index and dairy consumption in the D.E.S.I.R. study.Q51340893
Quantifying biases in causal models: classical confounding vs collider-stratification bias.Q52953016
The genetic variant of lactase persistence C (−13910) T as a risk factor for type I and II diabetes in the Finnish populationQ57365874
Demonstrating stratification in a European American populationQ57418313
Mendelian Randomization as Applied to Coronary Heart Disease, Including Recent Advances Incorporating New TechnologyQ58887142
Adult-type hypolactasia and calcium availability: decreased calcium intake or impaired calcium absorption?Q58971208
[A nationwide wealth score based on the 2000 Brazilian demographic census]Q81094372
Adult-type hypolactasia and calcium intake in polycystic ovary syndromeQ83203666
Effect of probiotic fermented milk on blood pressure: a meta-analysis of randomised controlled trialsQ34792447
Lactase persistence and milk consumption are associated with body height in Swedish preadolescents and adolescentsQ35202555
Association of the LCT-13910C>T polymorphism with obesity and its modulation by dairy products in a Mediterranean populationQ35592018
Diet, nutrition and the prevention of osteoporosisQ35670622
Cohort Profile Update: The 1982 Pelotas (Brazil) Birth Cohort StudyQ35749360
Dietary patterns and their associations with childhood obesity in ChinaQ36125756
Cohort profile: the 1982 Pelotas (Brazil) birth cohort studyQ36350857
Do the lactotripeptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trialsQ36590794
Changes in water and beverage intake and long-term weight changes: results from three prospective cohort studiesQ36774076
Associations of the lactase persistence allele and lactose intake with body composition among multiethnic childrenQ37126381
Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative).Q37744507
A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods.Q37838710
How sound is the science behind the dietary recommendations for dairy?Q38197425
Dairy consumption and pre-school, school-age and adolescent obesity in developed countries: a systematic review and meta-analysisQ38198159
The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activityQ38337282
A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?Q39094353
An association between lactose intolerance and anthropometric variables in the Sudanese Shagia tribe (East Africa).Q39127948
Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individualsQ41601635
Milk intake is not associated with ischaemic heart disease in observational or Mendelian randomization analyses in 98,529 Danish adultsQ41660814
Transcriptional downregulation of the lactase (LCT) gene during childhood.Q43004089
Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary IslandsQ43257874
Dairy consumption and incidence of hypertension: a dose-response meta-analysis of prospective cohort studiesQ43863321
Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotypeQ44606107
Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.Q44749835
Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999-2004.Q46552162
The lactase persistence -13910C>T polymorphism shows indication of association with abdominal obesity among Portuguese childrenQ46713449
Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns StudyQ46809019
Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult malesQ46813268
T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitroQ46814728
Milk feeding and dietary patterns predict weight and fat gains in infancyQ47207624
P275copyright licenseCreative Commons AttributionQ6905323
Creative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectenzymeQ8047
obesityQ12174
blood pressureQ82642
dietQ474191
birth cohortQ64532946
physiological phenomenonQ66615932
fluids and secretionsQ71417785
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)1573-1587
P577publication date2016-05-11
2016-10-01
P1433published inInternational Journal of EpidemiologyQ6051393
P1476titleAssociation of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
P478volume45

Reverse relations

cites work (P2860)
Q62516692Adaptation to milking agropastoralism in Chilean goat herders and nutritional benefit of lactase persistence
Q37640699Brazilian dietary patterns and the dietary approaches to stop hypertension (DASH) diet-relationship with metabolic syndrome and newly diagnosed diabetes in the ELSA-Brasil study.
Q30240202Causal inference in obesity research
Q49541973Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies
Q58578629Dairy Consumption and Cardiometabolic Diseases: Systematic Review and Updated Meta-Analyses of Prospective Cohort Studies
Q59333150Dairy intake revisited - associations between dairy intake and lifestyle related cardio-metabolic risk factors in a high milk consuming population
Q38661622Gene-Dairy Food Interactions and Health Outcomes: A Review of Nutrigenetic Studies
Q92221733Genetic determinants of beverage consumption: Implications for nutrition and health
Q48208845Genetically predicted milk consumption and bone health, ischemic heart disease and type 2 diabetes: a Mendelian randomization study
Q51736327Gut-microbiome-related LCT genotype and 2-year changes in body composition and fat distribution: the POUNDS Lost Trial.
Q60953843Lactose Intolerance, Dairy Avoidance, and Treatment Options
Q53109575Response to 'Challenge in interpretation of Mendelian randomization studies using lactase persistence as instrumental variable'.

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