| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1009723838 |
| P356 | DOI | 10.1038/TP.2016.200 |
| P932 | PMC publication ID | 5315555 |
| P698 | PubMed publication ID | 27754481 |
| P2093 | author name string | X Gao | |
| J Morales | |||
| J C O'Connor | |||
| D Santana-Coelho | |||
| J M Parrott | |||
| L Redus | |||
| P2860 | cites work | Cytokines sing the blues: inflammation and the pathogenesis of depression | Q24633065 |
| From inflammation to sickness and depression: when the immune system subjugates the brain | Q24633527 | ||
| Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity | Q24634258 | ||
| Agouti C57BL/6N embryonic stem cells for mouse genetic resources | Q36562560 | ||
| Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia. | Q36699392 | ||
| Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression | Q36848923 | ||
| Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration. | Q36945216 | ||
| Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge | Q36945317 | ||
| NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice | Q37030206 | ||
| Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors | Q37071182 | ||
| Quinolinic acid: an endogenous neurotoxin with multiple targets | Q38148752 | ||
| Microglial brain region-dependent diversity and selective regional sensitivities to aging. | Q38642851 | ||
| Modulation of hippocampal synaptic transmission by the kynurenine pathway member xanthurenic acid and other VGLUT inhibitors | Q39921706 | ||
| Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. | Q40402093 | ||
| Peripheral inflammation is associated with altered substantia nigra activity and psychomotor slowing in humans | Q40428160 | ||
| Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis. | Q40500968 | ||
| Neurobiology of fear responses: the role of the amygdala | Q41580973 | ||
| Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain? | Q42500404 | ||
| Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq | Q42776227 | ||
| Conceptual confluence: the kynurenine pathway as a common target for ketamine and the convergence of the inflammation and glutamate hypotheses of depression | Q43083700 | ||
| IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity | Q45115322 | ||
| L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning. | Q46018483 | ||
| Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons | Q46636521 | ||
| Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis | Q46933332 | ||
| A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality | Q48233112 | ||
| Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus | Q48422430 | ||
| Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding | Q48580831 | ||
| Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents | Q24656267 | ||
| Kynurenine 3-Monooxygenase: An Influential Mediator of Neuropathology | Q26782867 | ||
| Kynurenines in the mammalian brain: when physiology meets pathology | Q27003296 | ||
| The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications | Q28188380 | ||
| Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus | Q28264068 | ||
| Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse | Q28317802 | ||
| Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior | Q28508390 | ||
| Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors | Q28579694 | ||
| Targeted Deletion of Kynurenine 3-Monooxygenase in Mice: A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAIN | Q29306917 | ||
| Research domain criteria (RDoC): toward a new classification framework for research on mental disorders | Q29547877 | ||
| Elevations of endogenous kynurenic acid produce spatial working memory deficits | Q30491331 | ||
| Systemic L-Kynurenine sulfate administration disrupts object recognition memory, alters open field behavior and decreases c-Fos immunopositivity in C57Bl/6 mice. | Q30654478 | ||
| Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings | Q31036547 | ||
| A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice | Q33216000 | ||
| A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder. | Q33397741 | ||
| Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin | Q33715452 | ||
| CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression | Q33751166 | ||
| Dose-dependent effects of endotoxin on neurobehavioral functions in humans | Q34099178 | ||
| Assessment of spatial memory in mice | Q34137676 | ||
| Reciprocal regulation of the neural and innate immune systems | Q34206115 | ||
| Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons | Q34351574 | ||
| Inflammation-induced anhedonia: endotoxin reduces ventral striatum responses to reward | Q34514025 | ||
| Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. | Q34655648 | ||
| The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry | Q34660881 | ||
| l-Kynurenine Its synthesis and possible regulatory function in brain | Q34661906 | ||
| Immune system to brain signaling: neuropsychopharmacological implications. | Q34769827 | ||
| The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review | Q35071470 | ||
| Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder | Q35647362 | ||
| Cytokines and psychopathology: lessons from interferon-alpha | Q35970243 | ||
| Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior. | Q35995176 | ||
| The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice | Q36125191 | ||
| Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge | Q36183347 | ||
| Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory | Q36244916 | ||
| Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice. | Q36561722 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 10 | |
| P921 | main subject | inflammation | Q101991 |
| neurotoxicity | Q3338704 | ||
| P304 | page(s) | e918 | |
| P577 | publication date | 2016-10-18 | |
| P1433 | published in | Translational Psychiatry | Q15716636 |
| P1476 | title | Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation | |
| P478 | volume | 6 |
| Q96230071 | A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration |
| Q92660354 | Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression |
| Q47678641 | Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone |
| Q61453866 | Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress |
| Q90176765 | Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer |
| Q90163291 | Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice |
| Q88591012 | Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation |
| Q47387394 | LPS-induced cortical kynurenic acid and neurogranin-NFAT signaling is associated with deficits in stimulus processing during Pavlovian conditioning |
| Q89486095 | Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice |
| Q41699494 | Microglia: An Interface between the Loss of Neuroplasticity and Depression |
| Q92345091 | Non-toxic HSC Transplantation-Based Macrophage/Microglia-Mediated GDNF Delivery for Parkinson's Disease |
| Q90138268 | Prospective study of the effects of sport-related concussion on serum kynurenine pathway metabolites |
| Q38631578 | Protective role of cellular prion protein against TNFα-mediated inflammation through TACE α-secretase |
| Q38681297 | Rescue of IL-1β-induced reduction of human neurogenesis by omega-3 fatty acids and antidepressants |
| Q90564600 | Sex differences in depression-like behavior and neuroinflammation in rats post-MI: role of estrogens |
| Q90675855 | Stress-induced impairment in fear discrimination is causally related to increased kynurenic acid formation in the prefrontal cortex |
| Q93334893 | The Impact of Stress and Major Depressive Disorder on Hippocampal and Medial Prefrontal Cortex Morphology |
| Q93066099 | The kynurenine pathway: a finger in every pie |
| Q90169426 | Therapeutic Duration and Extent Affect the Effect of Moxibustion on Depression-Like Behaviour in Rats via Regulating the Brain Tryptophan Transport and Metabolism |
| Q38828405 | Therapeutic Implications of Brain-Immune Interactions: Treatment in Translation |
| Q90355553 | Tryptophan metabolites kynurenine and serotonin regulate fibroblast activation and fibrosis |
| Q47826628 | Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain. |
Search more.