scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1026220014 |
P356 | DOI | 10.1038/NPP.2013.71 |
P932 | PMC publication ID | 3717543 |
P698 | PubMed publication ID | 23511700 |
P5875 | ResearchGate publication ID | 236063945 |
P50 | author | Robert Dantzer | Q3434896 |
Keith W. Kelley | Q47809179 | ||
P2093 | author name string | Adam K Walker | |
Robin A Smith | |||
David P Budac | |||
Anna W Lee | |||
Brent Beenders | |||
Stephanie Bisulco | |||
P2860 | cites work | Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors | Q48099473 |
Stress- and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend on sympathetic nervous system activity | Q48635018 | ||
Acute inflammation and negative mood: mediation by cytokine activation | Q48863588 | ||
Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats | Q48880251 | ||
AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice. | Q52181935 | ||
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway | Q85047994 | ||
From inflammation to sickness and depression: when the immune system subjugates the brain | Q24633527 | ||
The role of eukaryotic elongation factor 2 kinase in rapid antidepressant action of ketamine | Q28276943 | ||
Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse | Q28317802 | ||
Human microglia convert l-tryptophan into the neurotoxin quinolinic acid | Q28379366 | ||
Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior | Q28508390 | ||
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses | Q30471587 | ||
Effects of cytokines on cerebral neurotransmission. Comparison with the effects of stress | Q33708133 | ||
Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin | Q33715452 | ||
Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: a pathway for the induction of non-specific symptoms of sickness? | Q33970888 | ||
Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior. | Q34012783 | ||
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. | Q34655648 | ||
The HPA axis in major depression: classical theories and new developments | Q34803590 | ||
Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide | Q35690505 | ||
Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior. | Q35995176 | ||
The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects | Q37067679 | ||
Regulatory role of anesthetics on heme oxygenase-1. | Q37779567 | ||
Dual roles for perivascular macrophages in immune-to-brain signaling | Q40665015 | ||
Cytokine-associated emotional and cognitive disturbances in humans | Q43601371 | ||
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection | Q43718624 | ||
Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. | Q43942974 | ||
Increase in concentration of waking salivary cortisol in recovered patients with depression | Q44599668 | ||
Conditioned taste aversion with lipopolysaccharide and peptidoglycan does not activate cytokine gene expression in the spleen and hypothalamus of mice. | Q44753772 | ||
Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains | Q46159780 | ||
Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma? | Q46515190 | ||
Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus | Q46989886 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lipopolysaccharide | Q421804 |
P304 | page(s) | 1609-1616 | |
P577 | publication date | 2013-03-19 | |
P1433 | published in | Neuropsychopharmacology | Q2261280 |
P1476 | title | NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice | |
P478 | volume | 38 |
Q92043421 | (R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism |
Q47741629 | A single dose of S-ketamine induces long-term antidepressant effects and decreases oxidative stress in adulthood rats following maternal deprivation. |
Q33553907 | Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice |
Q33635571 | Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome |
Q54966162 | Amelioration of Pentylenetetrazole-Induced Seizures by Modulators of Sigma, N-Methyl-D-Aspartate, and Ryanodine Receptors in Mice. |
Q37254521 | An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation |
Q90477448 | Animal models of major depression: drawbacks and challenges |
Q33635653 | Animal models to improve our understanding and treatment of suicidal behavior |
Q21129276 | Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants |
Q92660354 | Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression |
Q35902490 | Behavioral Deficits Are Accompanied by Immunological and Neurochemical Changes in a Mouse Model for Neuropsychiatric Lupus (NP-SLE). |
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Q37310546 | Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets |
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Q43083700 | Conceptual confluence: the kynurenine pathway as a common target for ketamine and the convergence of the inflammation and glutamate hypotheses of depression |
Q28830670 | Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression |
Q52667723 | Convergent Mechanisms Underlying Rapid Antidepressant Action. |
Q26772830 | Depression as a Glial-Based Synaptic Dysfunction |
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Q47999379 | Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide |
Q52564304 | Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice. |
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Q26781620 | Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment |
Q38954648 | Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders |
Q38366476 | Inflammation-induced activation of the indoleamine 2,3-dioxygenase pathway: Relevance to cancer-related fatigue |
Q37089253 | Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications |
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Q48362770 | Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour |
Q91652721 | Interactions between pyridostigmine bromide and stress on glutamatergic neurochemistry: Insights from a rat model of Gulf War Illness |
Q40352700 | Involvement of Host Defense Mechanisms against Toxoplasma gondii Infection in Anhedonic and Despair-Like Behaviors in Mice |
Q34051382 | Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression? |
Q55438088 | Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. |
Q38254452 | Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? |
Q37330681 | Ketamine: synaptogenesis, immunomodulation and glycogen synthase kinase-3 as underlying mechanisms of its antidepressant properties |
Q47722395 | Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression |
Q26782867 | Kynurenine 3-Monooxygenase: An Influential Mediator of Neuropathology |
Q36945317 | Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge |
Q37114639 | Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studies |
Q88591012 | Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation |
Q26773067 | Kynurenine pathway metabolites and suicidality |
Q21129356 | Kynurenines in CNS disease: regulation by inflammatory cytokines |
Q48571192 | LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain |
Q89486095 | Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice |
Q34357034 | Lipopolysaccharide reduces incentive motivation while boosting preference for high reward in mice |
Q30630772 | Lipopolysaccharide-induced depressive-like behavior is associated with α₁-adrenoceptor dependent downregulation of the membrane GluR1 subunit in the mouse medial prefrontal cortex and ventral tegmental area |
Q60304624 | Low dose aspirin blocks breast cancer-induced cognitive impairment in mice |
Q36749816 | Low-Level Stress Induces Production of Neuroprotective Factors in Wild-Type but Not BDNF+/- Mice: Interleukin-10 and Kynurenic Acid |
Q40500968 | Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis. |
Q30251615 | Mastocytosis in adulthood and neuropsychiatric disorders |
Q91868190 | Maternal immune activation in rats blunts brain cytokine and kynurenine pathway responses to a second immune challenge in early adulthood |
Q52658612 | Mechanisms of ketamine action as an antidepressant. |
Q48088648 | Microglia-dependent alteration of glutamatergic synaptic transmission and plasticity in the hippocampus during peripheral inflammation. |
Q41699494 | Microglia: An Interface between the Loss of Neuroplasticity and Depression |
Q89859733 | Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin |
Q60991606 | Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2,3 dioxygenase |
Q47744128 | NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction. |
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Q30839124 | Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation |
Q35554122 | Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice. |
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Q48061279 | Piperine Augments the Protective Effect of Curcumin Against Lipopolysaccharide-Induced Neurobehavioral and Neurochemical Deficits in Mice |
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Q26782274 | Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants |
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Q47415330 | Quantitative Analysis of Kynurenine Aminotransferase II in the Adult Rat Brain Reveals High Expression in Proliferative Zones and Corpus Callosum |
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Q39777451 | Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice. |
Q30449121 | Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behavior in mice |
Q35580361 | Rodent models of treatment-resistant depression. |
Q38893391 | Role of Adiposity-Driven Inflammation in Depressive Morbidity |
Q38885617 | Role of Inflammation in Suicide: From Mechanisms to Treatment |
Q38843536 | Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms. |
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