Neuropathology of mood disorders: do we see the stigmata of inflammation?

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Neuropathology of mood disorders: do we see the stigmata of inflammation? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/TP.2016.212
P932PMC publication ID5314124
P698PubMed publication ID27824355

P2093author name stringN Mechawar
J Savitz
P2860cites workGlial reduction in amygdala in major depressive disorder is due to oligodendrocytes.Q47969861
Inflammatory cytokines influence measures of white matter integrity in Bipolar DisorderQ48053565
Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicidesQ48081647
Interferon-β1a modulates glutamate neurotransmission in the CNS through CaMKII and GluN2A-containing NMDA receptorsQ48106435
Peripheral inflammation during abnormal mood states in bipolar I disorderQ36103950
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET.Q36155325
Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous SystemQ36227285
Loneliness, eudaimonia, and the human conserved transcriptional response to adversityQ36260185
Microglia in the TBI brain: The good, the bad, and the dysregulated.Q36399682
Altered Markers of Cortical γ-Aminobutyric Acid Neuronal Activity in Schizophrenia: Role of the NARP GeneQ36525031
The glutamate-glutamine cycle as an inducible, protective face of macrophage activationQ36567120
L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the 'collusion' hypothesis for increased extracellular L-glutamate concentration in neuroinflammationQ36618166
Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalitiesQ36625412
Glial reduction in the subgenual prefrontal cortex in mood disordersQ36651128
Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cordQ36691900
Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administrationQ36806349
Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorderQ36812629
Autoimmune Encephalitis in Postpartum PsychosisQ36862598
Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depressionQ36889327
Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2.Q36946523
Abnormal gene expression of proinflammatory cytokines and their membrane-bound receptors in the lymphocytes of depressed patientsQ36948381
NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J miceQ37030206
Glucose metabolism in the insula and cingulate is affected by systemic inflammation in humansQ37030301
Elevated cytokine expression in the orbitofrontal cortex of victims of suicideQ37032702
Reduced frontal-subcortical white matter connectivity in association with suicidal ideation in major depressive disorderQ37061873
Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes.Q37062133
Abnormal gene expression of proinflammatory cytokines and their receptors in the lymphocytes of patients with bipolar disorderQ37083101
Elevated levels of NR2A and PSD-95 in the lateral amygdala in depressionQ37104018
Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depressionQ37128042
Stress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behaviorQ37128151
Disease-specific alterations in glutamatergic neurotransmission on inhibitory interneurons in the prefrontal cortex in schizophreniaQ37149873
Frequency and characteristics of isolated psychiatric episodes in anti–N-methyl-d-aspartate receptor encephalitisQ37258132
A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1betaQ37300227
Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individualsQ37370987
GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depressionQ37408446
Regulation of innate immune responses in the brainQ37492253
Glutamate normalization with ECT treatment response in major depressionQ37495562
Increased levels of glutamate in brains from patients with mood disorders.Q48133783
Deficit of perineuronal oligodendrocytes in the prefrontal cortex in schizophrenia and mood disordersQ48137205
Increased plasma levels of soluble TNF receptors 1 and 2 in bipolar depression and impact of lithium treatmentQ48137846
The longitudinal association between inflammation and incident depressive symptoms in men: the effects of hs-CRP are independent of abdominal obesity and metabolic disturbancesQ48161624
Treatment-Resistant Depression and Aquaporin-4 Autoantibodies: Is There a Link?Q48166239
Increased white matter connectivity in euthymic bipolar patients: diffusion tensor tractography between the subgenual cingulate and the amygdalo-hippocampal complexQ48182423
Prenatal inhibition of the tryptophan-kynurenine pathway alters synaptic plasticity and protein expression in the rat hippocampusQ48192643
Comparison of pro-inflammatory cytokines among patients with bipolar disorder and unipolar depression and normal controlsQ48204136
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidalityQ48233112
Evidence for a neuroinflammatory mechanism in delayed effects of early life adversity in rats: relationship to cortical NMDA receptor expressionQ48269132
Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicidesQ48288128
Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicideQ48335595
Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patientsQ48357784
Elevated levels of IL-6 and IL-18 in manic and hypomanic states in rapid cycling bipolar disorder patientsQ48433920
Astrocytic complexity distinguishes the human brainQ48434985
Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokinesQ48440751
Interleukin-13 enhances cyclooxygenase-2 expression in activated rat brain microglia: implications for death of activated microgliaQ48479959
Autoimmunity in psychiatryQ48536905
Decreased glutamic acid decarboxylase(67) mRNA expression in multiple brain areas of patients with schizophrenia and mood disordersQ48689946
Electron microscopy of oligodendroglia in severe mental illness.Q48772850
Seroprevalence of autoantibodies against brain antigens in health and diseaseQ48774317
Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophreniaQ48891579
Association of high-sensitivity C-reactive protein with de novo major depressionQ48972863
Altered myelination of the hippocampal formation in subjects with schizophrenia and bipolar disorderQ49110783
Human social genomicsQ21092402
The myth of schizophrenia as a progressive brain diseaseQ24067152
Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth CohortQ24288638
In psychosis, cortical interneurons overexpress DNA-methyltransferase 1Q24556666
Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitisQ24614608
Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivityQ24634258
GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophreniaQ24642711
Differential alterations of kainate receptor subunits in inhibitory interneurons in the anterior cingulate cortex in schizophrenia and bipolar disorderQ24647600
Antibodies to Toxoplasma gondii in patients with schizophrenia: a meta-analysisQ24656702
Effects of Toxoplasma gondii infection on the brainQ24656964
Astrocyte pathology in major depressive disorder: insights from human postmortem brain tissueQ26827833
Quinolinic acid, the inescapable neurotoxinQ26991715
A putative functional role for oligodendrocytes in mood regulationQ26995174
Current approaches to enhance glutamate transporter function and expressionQ26996723
Microglial interactions with synapses are modulated by visual experienceQ27322943
The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.Q27863346
Antibody-mediated encephalitis: a treatable cause of schizophreniaQ28258673
Schizophrenia risk from complex variation of complement component 4Q28272545
White matter tractography in bipolar disorder and schizophreniaQ28295103
Physiology of microgliaQ29547414
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain studyQ29616193
A meta-analysis of cytokines in major depressionQ29617325
Microglial physiology: unique stimuli, specialized responsesQ29620417
Adult oligodendrocyte progenitor cells - Multifaceted regulators of the CNS in health and diseaseQ30277699
IL-4 in the brain: a cytokine to rememberQ30416623
Microglial displacement of inhibitory synapses provides neuroprotection in the adult brainQ30584811
Neuropathological and neuromorphometric abnormalities in bipolar disorder: view from the medial prefrontal cortical networkQ30772377
Finding the Elusive Psychiatric "Lesion" With 21st-Century Neuroanatomy: A Note of CautionQ30990470
Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy researchQ30995022
Kynurenines in the CNS: from endogenous obscurity to therapeutic importanceQ32148941
Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patientsQ33226446
Incidence of cytomegalovirus infection among the general population and pregnant women in the United States.Q33289670
Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium.Q51943076
High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure.Q51957863
Neuroinflammation in bipolar disorder - A [(11)C]-(R)-PK11195 positron emission tomography study.Q53071540
Elevated C-reactive protein and late-onset bipolar disorder in 78 809 individuals from the general population.Q53392930
White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imagingQ57316787
SnapShot: Stress and DiseaseQ61200307
Activated human microglia produce the excitotoxin quinolinic acidQ73175992
Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brainQ73447770
Are autoimmune thyroid dysfunction and depression related?Q77325012
The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNSQ77846814
Meta-analysis of 12 genomic studies in bipolar disorderQ80860524
Neuropsychiatric manifestations of multiple sclerosisQ81957990
The activation of monocyte and T cell networks in patients with bipolar disorderQ83737091
Cytokine alterations in bipolar disorder: a meta-analysis of 30 studiesQ86153175
Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migrationQ86492751
Glutamate transporters: a key piece in the glutamate puzzle of major depressive disorderQ33355898
Circuitry-based gene expression profiles in GABA cells of the trisynaptic pathway in schizophrenics versus bipolarsQ33395226
The excitotoxin quinolinic acid induces tau phosphorylation in human neuronsQ33485236
Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depressionQ33492323
Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depressionQ33553152
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkersQ33587452
IFN-alpha-induced cortical and subcortical glutamate changes assessed by magnetic resonance spectroscopyQ33620624
Uniquely hominid features of adult human astrocytesQ33644376
Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studiesQ33664090
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patientsQ33751063
High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbanceQ33814536
Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorderQ33846348
Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorderQ33978656
N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trialQ34012103
Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?Q34051382
Elevated levels of the NR2C subunit of the NMDA receptor in the locus coeruleus in depressionQ34065490
System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivoQ34073426
Microglia of prefrontal white matter in suicideQ34076322
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depressionQ34084102
Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depressionQ34084772
Toxoplasma gondii antibody titers and history of suicide attempts in patients with recurrent mood disordersQ34088066
Inflammation-associated depression: from serotonin to kynurenineQ34147377
Autoimmune diseases, bipolar disorder, and non-affective psychosisQ34179648
Peripheral inflammation acutely impairs human spatial memory via actions on medial temporal lobe glucose metabolismQ34199733
Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood DisordersQ34204211
Oligodendrocyte dysfunction in schizophrenia and bipolar disorderQ34246905
An open-label trial of riluzole in patients with treatment-resistant major depressionQ34287364
Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephaQ34323973
Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorderQ34331509
Brain glutamate levels measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta-analysisQ34352492
Antibodies to Toxoplasma gondii in individuals with maniaQ34376089
Alterations in cortical network oscillations and parvalbumin neurons in schizophreniaQ34471254
Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorderQ34480323
Morphometric characterization of microglial phenotypes in human cerebral cortexQ37532369
Phenotypic heterogeneity and plasticity of isocortical and hippocampal astrocytes in the human brainQ37555027
Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: implications for schizophreniaQ37580309
Markers of inflammation and stress distinguish subsets of individuals with schizophrenia and bipolar disorderQ37621319
Astrocytic abnormalities and global DNA methylation patterns in depression and suicideQ37626767
Familial comorbidity of bipolar disorder and multiple sclerosis: genetic susceptibility, coexistence or causal relationship?Q37627409
Toll-like receptors in the depressed and suicide brainQ37731799
Neurobiology of injury to the developing brainQ37755972
Inflammation, demyelination, and degeneration - recent insights from MS pathology.Q37773548
Clinical depression and inflammatory risk markers for coronary heart diseaseQ37870585
Inflammation, depressive symptomtology, and coronary artery diseaseQ37875574
Type 1 diabetes mellitus and major depressive disorder: evidence for a biological linkQ37905722
Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysisQ38114586
Crying and suicidal, but not depressed. Pseudobulbar affect in multiple sclerosis successfully treated with valproic acid: Case report and literature reviewQ38219309
Taking the fuel out of the fire: evidence for the use of anti-inflammatory agents in the treatment of bipolar disorders.Q38305248
Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study.Q38425887
The role of inflammation in depression: from evolutionary imperative to modern treatment targetQ38681725
Inhibiting neuroinflammation: The role and therapeutic potential of GABA in neuro-immune interactionsQ38724866
Interferon-α induces neurotoxicity through activation of the type I receptor and the GluN2A subunit of the NMDA receptorQ39396414
Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completersQ39542626
Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depressionQ39793664
Modulation of hippocampal synaptic transmission by the kynurenine pathway member xanthurenic acid and other VGLUT inhibitorsQ39921706
Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes.Q40099434
Sex differences in glutamate receptor gene expression in major depression and suicideQ40742522
Inflammatory evidence for the psychosis continuum modelQ40774386
Relationship Between Toxoplasma gondii and Mood Disturbance in Women VeteransQ41191827
Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation.Q41257707
C-reactive protein alterations in bipolar disorder: a meta-analysisQ41289839
Response of glial cells to ischemia: roles of reactive oxygen species and glutathioneQ41377079
Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brainQ41605555
Reduced GABA neuron density in auditory cerebral cortex of subjects with major depressive disorder.Q41646482
A single vesicular glutamate transporter is sufficient to fill a synaptic vesicleQ42075361
Single and combined effects of prenatal immune activation and peripubertal stress on parvalbumin and reelin expression in the hippocampal formationQ42216776
Consistent associations between measures of psychological stress and CMV antibody levels in a large occupational sample.Q42240482
Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2.Q42315823
Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorderQ42604899
Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation familyQ42683853
Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers.Q43105498
Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophreniaQ43258935
Stress-induced immune dysfunction: implications for healthQ43472077
Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorderQ43593933
Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reactionQ43621641
Striatal excitatory amino acid transporter transcript expression in schizophrenia, bipolar disorder, and major depressive disorderQ43890441
The density and spatial distribution of GABAergic neurons, labelled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia.Q43923756
Different changes in cortical tumor necrosis factor-α-related pathways in schizophrenia and mood disordersQ43997962
Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophreniaQ44014143
Low glial numbers in the amygdala in major depressive disorderQ44145406
Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytesQ44294994
Decreased N-acetylaspartate in children with familial bipolar disorderQ44466569
A novel, rapid, quantitative cell-counting method reveals oligodendroglial reduction in the frontopolar cortex in major depressive disorderQ44484522
Association of exaggerated HPA axis response to the initial injection of interferon-alpha with development of depression during interferon-alpha therapy.Q44495175
Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanismQ45081990
Preterm birth and psychiatric disorders in young adult lifeQ45368495
Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorderQ45497214
National seroprevalence and trends in herpes simplex virus type 1 in the United States, 1976-1994.Q45533092
Successful execution of working memory linked to synchronized high-frequency gamma oscillationsQ45881657
Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completersQ46174413
Immune-to-brain signalling: the role of cerebral CD163-positive macrophagesQ46318926
Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disordersQ46461905
A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes.Q46662600
A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonistsQ46703076
Down-regulation of astrocytic GLAST by microglia-related inflammation is abrogated in dibutyryl cAMP-differentiated culturesQ46734834
Lamina-specific abnormalities of NMDA receptor-associated postsynaptic protein transcripts in the prefrontal cortex in schizophrenia and bipolar disorderQ46886163
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorderQ46974964
Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder.Q47191236
Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder.Q47207451
Stress, loneliness, and changes in herpesvirus latencyQ47601943
Inflammation-induced anhedonia: endotoxin reduces ventral striatum responses to rewardQ34514025
Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytesQ34582826
Is autoimmune thyroiditis part of the genetic vulnerability (or an endophenotype) for bipolar disorder?Q34586552
Gene expression deficits in pontine locus coeruleus astrocytes in men with major depressive disorderQ34588846
Pseudobulbar affect: prevalence and managementQ34658447
The role of NMDA receptors in the pathophysiology and treatment of mood disorders.Q34664587
Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes.Q34667721
Are some cases of psychosis caused by microbial agents? A review of the evidenceQ34749296
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissueQ34754753
Immune system to brain signaling: neuropsychopharmacological implications.Q34769827
Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorderQ34979782
Treatment of cytokine-induced depressionQ34980861
Herpesviruses, inflammatory markers and incident depression in a longitudinal study of Detroit residentsQ35012816
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humansQ35017005
Distribution of vesicular glutamate transporters in the human brainQ35149796
Association of rare variation in the glutamate receptor gene SLC1A2 with susceptibility to bipolar disorder and schizophrenia.Q35154322
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathwayQ35168537
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?Q35225947
Proinflammatory cytokines in the prefrontal cortex of teenage suicide victimsQ35573452
Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identificationQ35581623
Astrocytic hypertrophy in anterior cingulate white matter of depressed suicidesQ35592026
Environmental Basis of AutoimmunityQ35638839
Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorderQ35647362
RETRACTED: Dysregulated glutamate and dopamine transporters in postmortem frontal cortex from bipolar and schizophrenic patientsQ35662070
Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4Q35705851
Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trialQ35789318
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory DemyelinationQ35815842
Cytokines and psychopathology: lessons from interferon-alphaQ35970243
Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal studyQ36032535
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
brainQ1073
bipolar disorderQ131755
nervous systemQ9404
major depressive disorderQ42844
inflammation mediatorsQ66765004
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)e946
P577publication date2016-11-08
P1433published inTranslational PsychiatryQ15716636
P1476titleNeuropathology of mood disorders: do we see the stigmata of inflammation?
P478volume6

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cites work (P2860)
Q102323849A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder
Q96230071A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration
Q58082651Abnormal protein and mRNA expression of inflammatory cytokines in the prefrontal cortex of depressed individuals who died by suicide
Q91635047Adult neuroplasticity: A new “cure” for major depression?
Q47414228Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder
Q40147546Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: Association with sleep disturbance
Q47148667Antidepressant-Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models
Q97066977Antidepressant-Like Effects of Coumaroylspermidine Extract From Safflower Injection Residues
Q90454383Biological Mechanisms of Cancer-Induced Depression
Q64945797Buprenorphine: Therapeutic potential beyond substance abuse.
Q48192046Chemical interaction between Lilium brownii and Rhizoma Anemarrhenae, the herbal constituents of Baihe Zhimu decoction, by liquid chromatography coupled to hybrid triple quadrupole linear ion trap mass spectrometer.
Q52356865Clinical Findings Documenting Cellular and Molecular Abnormalities of Glia in Depressive Disorders.
Q64118633Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health
Q47682578Effects of acute systemic inflammation on the interplay between sad mood and affective cognition
Q47643969Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages.
Q58554142Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective
Q39335649Heterogeneous populations of neural stem cells contribute to myelin repair.
Q89658753Innate Immunity: A Common Denominator between Neurodegenerative and Neuropsychiatric Diseases
Q91856535Innate immunity in the postmortem brain of depressed and suicide subjects: Role of Toll-like receptors
Q64078645Integrative Analysis of DiseaseLand Omics Database for Disease Signatures and Treatments: A Bipolar Case Study
Q54942001Is poststroke depression the same as major depression?
Q47722395Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression
Q89723642Less NMDA Receptor Binding in Dorsolateral Prefrontal Cortex and Anterior Cingulate Cortex Associated with Reported Early Life Adversity but Not Suicide
Q47140966Modulating Neuroinflammation to Treat Neuropsychiatric Disorders
Q61816652Mood Disorders, Accelerated Aging, and Inflammation: Is the Link Hidden in Telomeres?
Q38694557Neurobehavioral comorbidities of epilepsy: Role of inflammation.
Q64108001Neurointegrity and neurophysiology: astrocyte, glutamate, and carbon monoxide interactions
Q38659366Neuropathology of suicide: recent findings and future directions.
Q49244418Neurotrophic, Cytoprotective, and Anti-inflammatory Effects of St. John's Wort Extract on Differentiated Mouse Hippocampal HT-22 Neurons
Q38799706Novel rodent model of breast cancer survival with persistent anxiety-like behavior and inflammation.
Q61449859Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse
Q41605478Open Label Trial of the Efficacy and Safety Profile of Rikkunshito used for the Treatment of Gastrointestinal Symptoms in Patients with Parkinson's Disease: A Pilot Study
Q61806045Role of Soluble Epoxide Hydrolase in Metabolism of PUFAs in Psychiatric and Neurological Disorders
Q39258097Social defeat models in animal science: What we have learned from rodent models
Q64257788Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies
Q93066099The kynurenine pathway: a finger in every pie
Q47648526Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial
Q64029499Treatment-resistant depression and peripheral C-reactive protein
Q47551793Tulsa 1000: a naturalistic study protocol for multilevel assessment and outcome prediction in a large psychiatric sample.
Q61444284Tumor resection ameliorates tumor-induced suppression of neuroinflammatory and behavioral responses to an immune challenge in a cancer survivor model
Q64923151Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder.
Q33829223cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress

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