Using dried blood spot sampling to improve data quality and reduce animal use in mouse pharmacokinetic studies

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Using dried blood spot sampling to improve data quality and reduce animal use in mouse pharmacokinetic studies is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4382617
P698PubMed publication ID25836959

P2093author name stringEnaksha R Wickremsinhe
Everett J Perkins
P2860cites workDevelopment and validation of a dried blood spot-LC-APCI-MS assay for estimation of canrenone in paediatric samplesQ33445178
Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small moleculesQ33519108
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Capillary microsampling in the regulatory environment: validation and use of bioanalytical capillary microsampling methodsQ34619227
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Dried-blood spot screening for cystic fibrosis in the newbornQ39534705
A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokineticsQ41931661
Use of dried blood spots in drug development: pharmacokinetic considerationsQ42739574
The Application of Dried Blood Spot Sampling in Global Clinical TrialsQ43323352
Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography-mass spectrometry.Q43585792
Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studiesQ43656996
Dried blood spots improve access to HIV diagnosis and care for infants in low-resource settingsQ43708627
Validation of a bioanalytical method using capillary microsampling of 8 µl plasma samples: application to a toxicokinetic study in miceQ44514074
Capillary microsampling of 25 µl blood for the determination of toxicokinetic parameters in regulatory studies in animalsQ45750494
Utilization of DBS Within Drug Discovery: Development of a Serial Microsampling Pharmacokinetic Study in MiceQ45998866
Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: considerations for the validation of a quantitative bioanalytical method.Q46156878
Evaluation of dried blood spot (DBS) technology versus plasma analysis for the determination of MK-1775 by HILIC-MS/MS in support of clinical studiesQ46441349
Discovery pharmacokinetic studies in mice using serial microsampling, dried blood spots and microbore LC-MS/MS.Q47735810
A novel approach to capillary plasma microsampling for quantitative bioanalysis.Q50491603
Preclinical bridging studies: understanding dried blood spot and plasma exposure profiles.Q51275877
DNA microextraction from dried blood spots on filter paper blotters: potential applications to newborn screeningQ70170462
Discovery stage pharmacokinetics using dried blood spotsQ80391679
Pharmacokinetic Considerations as to When to Use Dried Blood Spot SamplingQ82483142
Perforated dried blood spot accurate microsampling: the concept and its applications in toxicokinetic sample collectionQ84108911
Application of automated serial blood sampling and dried blood spot technique with liquid chromatography-tandem mass spectrometry for pharmacokinetic studies in miceQ84588692
Development and validation of a dried blood spot LC-MS/MS assay to quantify ranitidine in paediatric samplesQ84886291
Pre-cut dried blood spot (PCDBS): an alternative to dried blood spot (DBS) technique to overcome hematocrit impactQ95383960
P433issue2
P921main subjectpharmacokineticsQ323936
data qualityQ1757694
P304page(s)139-144
P577publication date2015-03-01
P1433published inJournal of the American Association for Laboratory AnimalsQ15763143
P1476titleUsing dried blood spot sampling to improve data quality and reduce animal use in mouse pharmacokinetic studies
P478volume54

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Q43212998Special issue: global 3Rs efforts - making progress and gaining momentumcites workP2860

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