REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells

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REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1039593705
P356DOI10.1038/SJ.ONC.1206397
P698PubMed publication ID12771942
P5875ResearchGate publication ID7131796

P2093author name stringJ Anton Grootegoed
Leen J Blok
Josien K Oosterhoff
Albert O Brinkmann
Fred Penninkhof
P2860cites workThe human prostatic cancer cell line LNCaP and its derived sublines: an in vitro model for the study of androgen sensitivityQ37544438
Influence of dihydrotestosterone, epidermal growth factor, and basic fibroblast growth factor on the cell kinetics of the PC3, DU145, and LNCaP prostatic cancer cell lines: relationship with DNA ploidy levelQ39368327
The post-translational modifications of Ral and Rac1 are important for the action of Ral-binding protein 1, a putative effector protein of Ral.Q41103610
Control of EGF receptor signaling by clathrin-mediated endocytosis.Q45345953
Endocytosis proteins and cancer: a potential link?Q47686987
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAsQ22066003
Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of RalQ24318512
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activityQ24337472
Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptorsQ24534185
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPasesQ24651430
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factorQ28288345
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathwayQ29614258
Endocytosis and mitogenic signalingQ33712434
Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathwaysQ33774714
Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylationQ33898116
Suppression of Ras-induced apoptosis by the Rac GTPaseQ33959056
Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survivalQ33959533
Ras and Rho regulation of the cell cycle and oncogenesisQ34326213
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)2920-2925
P577publication date2003-05-01
P1433published inOncogeneQ1568657
P1476titleREPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells
P478volume22

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cites work (P2860)
Q36857274Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling
Q43185634Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity.
Q34354134EGF signalling in prostate cancer cell lines is inhibited by a high expression level of the endocytosis protein REPS2.
Q42119540Epsins' novel role in cancer cell invasion
Q37146994Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates
Q33832517Gene expression pathways of high grade localized prostate cancer
Q36744205Hsf-1 and POB1 induce drug sensitivity and apoptosis by inhibiting Ralbp1
Q34325532Identification of REPS2 as a putative modulator of NF-kappaB activity in prostate cancer cells
Q51836057Identification of a microdeletion at Xp22.13 in a Taiwanese family presenting with Nance-Horan syndrome
Q36043833Novel Gene Expression Signature Predictive of Clinical Recurrence After Radical Prostatectomy in Early Stage Prostate Cancer Patients
Q47340259RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer
Q37741408RLIP76 Targeted Therapy for Kidney Cancer
Q38749340RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer
Q37146979RLIP76: A novel glutathione-conjugate and multi-drug transporter
Q33867008RLIP76: a versatile transporter and an emerging target for cancer therapy
Q36408355Recurrent and novel SS18-SSX fusion transcripts in synovial sarcoma: description of three new cases
Q37194622Regression of prostate cancer xenografts by RLIP76 depletion
Q30051796Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76
Q37154223Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.
Q35083727The RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery
Q24316124The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins
Q24295295The epsin family of endocytic adaptors promotes fibrosarcoma migration and invasion
Q36609767Therapeutic resistance in lung cancer
Q47095142Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection
Q37327593miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.

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