Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76

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Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76 is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3892/IJO.22.4.713
P3181OpenCitations bibliographic resource ID4849383
P932PMC publication ID2916676
P698PubMed publication ID19424567
P5875ResearchGate publication ID10860748

P2093author name stringPiotr Zimniak
Sanjay Awasthi
Jyotsana Singhal
Jizhong Cheng
Sharad Singhal
Yogesh Awasthi
P2860cites workNovel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicinQ22254720
RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytesQ24291401
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Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activityQ24337472
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell lineQ24338329
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RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosisQ28141762
HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivoQ28181223
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76Q28182524
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicityQ28182550
Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cellsQ28203126
RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosisQ28207629
RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobioticsQ28215022
A putative effector of Ral has homology to Rho/Rac GTPase activating proteinsQ28512740
Cytocentrin is a Ral-binding protein involved in the assembly and function of the mitotic apparatusQ28579981
Biochemistry of multidrug resistance mediated by the multidrug transporterQ29616476
The multidrug resistance protein family.Q30323786
Differential expression of sphingolipids in MRP1 overexpressing HT29 cellsQ30881625
REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cellsQ30938786
Identification of membrane-anchoring domains of RLIP76 using deletion mutant analysesQ33210207
Monitoring interactions at ATP-dependent drug efflux pumpsQ34023770
Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoproteinQ34130602
POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosisQ34393707
A Ral guanine exchange factor-Ral pathway is conserved in Drosophila melanogaster and sheds new light on the connectivity of the Ral, Ras, and Rap pathwaysQ34463200
Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer.Q34608865
Small cell carcinoma of the bladder: a case report and a literature reviewQ35121537
Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistanceQ35179100
Resected non-small cell lung cancer: need for adjuvant lymph node treatment? From hope to reality.Q35581379
Linking stress-signaling, glutathione metabolism, signaling pathways and xenobiotic transportersQ36721034
Hsf-1 and POB1 induce drug sensitivity and apoptosis by inhibiting Ralbp1Q36744205
Diminished drug transport and augmented radiation sensitivity caused by loss of RLIP76Q36982690
Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugatesQ37146994
RLIP76 in defense of radiation poisoningQ37146998
Organic anion-transporting ATPase of rat liver. I. Purification, photoaffinity labeling, and regulation by phosphorylationQ38302679
Regression of melanoma in a murine model by RLIP76 depletionQ38315672
The effectiveness of the anthracycline analog 4'-epidoxorubicin in the treatment of experimental tumors: a reviewQ39818231
Mitogenic and drug-resistance mediating effects of PKCalpha require RLIP76.Q40247154
Determinants of differential doxorubicin sensitivity between SCLC and NSCLC.Q40297526
The role of PKCalpha and RLIP76 in transport-mediated doxorubicin-resistance in lung cancerQ40387322
Anthracycline antibiotics in cancer therapy. Focus on drug resistanceQ40388183
Depletion of RLIP76 sensitizes lung cancer cells to doxorubicinQ40410738
Combination therapy with probucol prevents adriamycin-induced cardiomyopathyQ40415594
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer.Q40459619
RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistanceQ40512245
Low p27Kip1 expression is an independent adverse prognostic factor in patients with multiple myeloma.Q40606160
HT1080/DR4: a P-glycoprotein-negative human fibrosarcoma cell line exhibiting resistance to topoisomerase II-reactive drugs despite the presence of a drug-sensitive topoisomerase II.Q41718693
Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequencesQ43574003
Modulation of glucose-6-phosphate dehydrogenase activity and expression is associated with aryl hydrocarbon resistance in vitroQ43681979
Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stressQ43720112
RLIP76 is a major determinant of radiation sensitivityQ46604639
ATP-Dependent colchicine transport by human erythrocyte glutathione conjugate transporter.Q52221583
Cellular predictive factors of drug resistance in non-small cell lung carcinomas.Q53953903
MDR1 gene expression in lung cancer.Q54346895
Lung cancerQ73858423
Role of paxillin in metabolic oxidative stress-induced cytoskeletal reorganization: involvement of SAPK signal transduction pathway and PTP-PEST gene expressionQ74233648
ATP-Dependent human erythrocyte glutathione-conjugate transporter. I. Purification, photoaffinity labeling, and kinetic characteristics of ATPase activityQ74457045
ATP-Dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activityQ74457048
P921main subjectdoxorubicinQ18936
lung cancerQ47912
P577publication date2003-04-01
P1433published inInternational Journal of OncologyQ6051527
P1476titleRole of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76

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cites work (P2860)
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Q41109739Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress
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Q39322595Cell type-specific effects of Adenosine 5'-triphosphate and pyrophosphate on the antitumor activity of doxorubicin
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Q92382628Knockdown of RAP2A gene expression suppresses cisplatin resistance in gastric cancer cells
Q39215770Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells
Q34167090Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma
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Q60912518Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation
Q53793272Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and doxorubicin pharmacokinetics in Asian breast cancer patients.
Q34559882Potentiation of in vitro and in vivo antitumor efficacy of doxorubicin by cyclin-dependent kinase inhibitor P276-00 in human non-small cell lung cancer cells
Q35073746Quercetin-induced cardioprotection against doxorubicin cytotoxicity
Q39042820The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cells
Q38823143Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing?
Q38649748Visfatin mediates doxorubicin resistance in human non-small-cell lung cancer via Akt-mediated up-regulation of ABCC1.

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