Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination

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Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination is …
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P819ADS bibcode2011PLoSO...622718S
P356DOI10.1371/JOURNAL.PONE.0022718
P932PMC publication ID3143185
P698PubMed publication ID21799939
P5875ResearchGate publication ID51531343

P50authorRama Rao AmaraQ88444844
Suraj B. SableQ55188035
P2093author name stringJames E Posey
Bonnie B Plikaytis
Sunita Sharma
Thomas M Shinnick
Subhadra Nandakumar
Kathryn L Kellar
Kakali Bandyopadhyay
Mani Cheruvu
P2860cites workIntranasal vaccination with messenger RNA as a new approach in gene therapy: use against tuberculosisQ21256673
Future Vaccination Strategies against Tuberculosis: Thinking outside the BoxQ22252427
A new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteersQ24657992
Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal modelQ24675231
Extraordinarily few organisms of a live recombinant BCG vaccine against tuberculosis induce maximal cell-mediated and protective immunityQ28269283
The population dynamics and control of tuberculosisQ28282446
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factorQ29619247
Novel bacterial delivery system with attenuated Salmonella typhimurium carrying plasmid encoding Mtb antigen 85A for mucosal immunization: establishment of proof of principle in TB mouse model.Q30352384
Decreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern.Q30804006
Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen doseQ33468422
Mycobacterium bovis BCG induces similar immune responses and protection by rectal and parenteral immunization routesQ33591737
Human T cells recognize mycobacterial heat shock proteins in the context of multiple HLA-DR molecules: studies with healthy subjects vaccinated with Mycobacterium bovis BCG and Mycobacterium lepraeQ33617454
Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in miceQ33839055
The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adultsQ33950119
Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosisQ34000833
Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responsesQ34002292
Identification of mycobacterial surface proteins released into subcellular compartments of infected macrophagesQ34005306
Lymphocyte recruitment and protective efficacy against pulmonary mycobacterial infection are independent of the route of prior Mycobacterium bovis BCG immunizationQ34120343
Improved tuberculosis DNA vaccines by formulation in cationic lipidsQ34126930
Surface expression of MPT64 as a fusion with the PE domain of PE_PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in miceQ34309667
Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humansQ34361636
Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting?Q34401214
Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria.Q34525095
T cell immunity in lymphoid and non-lymphoid tissuesQ34712720
The Apa protein of Mycobacterium tuberculosis stimulates gamma interferon-secreting CD4+ and CD8+ T cells from purified protein derivative-positive individuals and affords protection in a guinea pig modelQ34854931
Definition of the full extent of glycosylation of the 45-kilodalton glycoprotein of Mycobacterium tuberculosisQ35606285
Characterization of the internalization of bacillus Calmette-Guerin by human bladder tumor cellsQ35823499
Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosisQ35927959
The bone marrow: a nest for migratory memory T cells.Q36174862
The success and failure of BCG - implications for a novel tuberculosis vaccineQ36191944
Single intranasal mucosal Mycobacterium bovis BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosisQ36229158
Noninvasive delivery technologies: respiratory delivery of vaccinesQ36349694
Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infectionQ36593990
Tuberculosis subunit vaccine design: the conflict of antigenicity and immunogenicity.Q36701672
Should a new tuberculosis vaccine be administered intranasally?Q36744991
Primary activation of antigen-specific naive CD4+ and CD8+ T cells following intranasal vaccination with recombinant bacteriaQ36974497
Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein activates dendritic cells and induces a Th1 polarizationQ37256545
Is intranasal vaccination a feasible solution for tuberculosis?Q37316013
A heterologous DNA priming-Mycobacterium bovis BCG boosting immunization strategy using mycobacterial Hsp70, Hsp65, and Apa antigens improves protection against tuberculosis in miceQ37623702
Tuberculosis: what we don't know can, and does, hurt us.Q37751647
Aerosol vaccines for tuberculosis: A fine line between protection and pathologyQ37808562
Mycobacterium tuberculosis arabinomannan-protein conjugates protect against tuberculosisQ38451771
Lung and blood mononuclear cell responses of tuberculosis patients to mycobacterial proteinsQ40273548
Nanobead-based interventions for the treatment and prevention of tuberculosisQ44117645
Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosisQ44681127
Novel prophylactic and therapeutic vaccine against tuberculosisQ44792823
Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guérin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus AnkaraQ45722508
Comparative evaluation of intranasal and subcutaneous route of immunization for development of mucosal vaccine against experimental tuberculosisQ46572484
Intranasal bacille Calmette-Guerin (BCG) vaccine dosage needs balancing between protection and lung pathologyQ47895673
Mucosal delivery of microparticle encapsulated ESAT-6 induces robust cell-mediated responses in the lung milieu.Q51483271
Envisioning future strategies for vaccination against tuberculosis.Q53230123
Dose of BCG does not influence the efficient generation of protective immunity in mice challenged with Mycobacterium tuberculosis.Q53938703
Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity.Q54453283
Recombinant GroES in combination with CpG oligodeoxynucleotides protects mice against Mycobacterium avium infection.Q54534077
The Influence of Remaining Live BCG Organisms in Vaccinated Mice on the Maintenance of Immunity to TuberculosisQ58827830
A new vaccine against tuberculosis shows greater protection in a mouse model with progressive pulmonary tuberculosisQ62607993
Natural history of pertussis antibody in the infant and effect on vaccine responseQ68727725
Isolation and characterization of mouse nasal-associated lymphoid tissueQ73233436
Role of a bacillus Calmette-Guérin fibronectin attachment protein in BCG-induced antitumor activityQ73574127
Intranasal vaccination of mice against infection with Mycobacterium tuberculosisQ73930782
The Mycobacterium tuberculosis cell-surface glycoprotein apa as a potential adhesin to colonize target cells via the innate immune system pulmonary C-type lectin surfactant protein AQ79422100
Enhanced immunoprotective potential of Mycobacterium tuberculosis Ag85 complex protein based vaccine against airway Mycobacterium tuberculosis challenge following intranasal administrationQ79870527
Mucosal immunization with recombinant heparin-binding haemagglutinin adhesin suppresses extrapulmonary dissemination of Mycobacterium bovis bacillus Calmette-Guérin (BCG) in infected miceQ80485791
Multicomponent antituberculous subunit vaccine based on immunodominant antigens of Mycobacterium tuberculosisQ81795473
Protective efficacy of intranasal vaccination with Mycobacterium bovis BCG against airway Mycobacterium tuberculosis challenge in miceQ82406166
Airway luminal T cells: a newcomer on the stage of TB vaccination strategiesQ84393604
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium tuberculosisQ130971
P304page(s)e22718
P577publication date2011-07-25
P1433published inPLOS OneQ564954
P1476titleCellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination
P478volume6