In Vivo Imaging of Human Neuroinflammation

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In Vivo Imaging of Human Neuroinflammation is …
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scholarly articleQ13442814

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P356DOI10.1021/ACSCHEMNEURO.6B00056
P932PMC publication ID5433433
P698PubMed publication ID26985861
P5875ResearchGate publication ID298797698

P50authorCristina GranzieraQ42434014
Jacob M. HookerQ52280455
P2093author name stringDaniel S Albrecht
Marco L Loggia
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Spinal translocator protein alleviates chronic neuropathic pain behavior and modulates spinal astrocyte-neuronal function in rats with L5 spinal nerve ligation model.Q50942553
Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers.Q53091381
Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.Q53164158
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Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction.Q54620115
Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injuryQ57089059
Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PETQ70317910
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Reactive gliosis and monoamine oxidase BQ72728908
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The upregulation of translocator protein (18 kDa) promotes recovery from neuropathic pain in ratsQ85945587
Magnetic resonance spectroscopy of the brain: a review of physical principles and technical methodsQ30982065
Nonconventional MRI and microstructural cerebral changes in multiple sclerosis.Q31015218
MRI morphometry in Alzheimer's diseaseQ31039994
Gray matter alterations in chronic pain: A network-oriented meta-analytic approachQ33741419
Use of in vivo two-dimensional MR spectroscopy to compare the biochemistry of the human brain to that of glioblastomaQ33831506
Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV.Q33834306
Neurologic 3D MR spectroscopic imaging with low-power adiabatic pulses and fast spiral acquisitionQ34107466
MR spectroscopic studies of the brain in psychiatric disordersQ34147260
Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammationQ34171364
Induction of COX-2 enzyme and down-regulation of COX-1 expression by lipopolysaccharide (LPS) control prostaglandin E2 production in astrocytesQ34244599
Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis.Q34283368
Advanced MRI unravels the nature of tissue alterations in early multiple sclerosisQ34286763
Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implicationsQ34432388
Evidence for brain glial activation in chronic pain patientsQ34457857
Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosisQ34472457
Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndromeQ34488155
Pathophysiological Roles of Cyclooxygenases and Prostaglandins in the Central Nervous SystemQ34491870
Is there an association between peripheral immune markers and structural/functional neuroimaging findings?Q34546439
Positron emission tomography and functional characterization of a complete PBR/TSPO knockout.Q34677691
Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords.Q34709354
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Molecular imaging of apoptosis: from micro to macro.Q35227490
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Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.Q35740284
Imaging neuroinflammation? A perspective from MR spectroscopy.Q35824849
Brain tissue compartment density estimated using diffusion-weighted MRI yields tissue parameters consistent with histologyQ35985392
Noninvasive molecular imaging of neuroinflammationQ36079268
Enlargement of choroid plexus in complex regional pain syndromeQ36099117
Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyQ36186141
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Early astrocytosis in autosomal dominant Alzheimer's disease measured in vivo by multi-tracer positron emission tomographyQ36265825
TSPO in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiologyQ36396082
Altered neurochemical profile after traumatic brain injury: (1)H-MRS biomarkers of pathological mechanismsQ36459054
Activity-triggered tetrapartite neuron-glial interactions following peripheral injuryQ36474044
Brain nicotinic acetylcholine receptors: native subtypes and their relevance.Q36550823
Heat-Induced Radiolabeling of Nanoparticles for Monocyte Tracking by PET.Q36581653
The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imagingQ36677808
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammationQ36684216
Modulation of inflammation in brain: a matter of fat.Q36719738
Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study.Q36766806
Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration referenceQ36770873
Distribution volume ratios without blood sampling from graphical analysis of PET dataQ36817029
Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator ProteinQ36821286
Acetate reduces PGE2 release and modulates phospholipase and cyclooxygenase levels in neuroglia stimulated with lipopolysaccharideQ36951565
In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.Q36953874
Imaging neuroinflammation in Alzheimer's disease with radiolabeled arachidonic acid and PET.Q36983897
Adenosine A2A receptors in secondary progressive multiple sclerosis: a [(11)C]TMSX brain PET study.Q37150330
Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brainQ37221310
Non-invasive visualization of CNS inflammation with nuclear and optical imagingQ37317306
P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia.Q37364487
Labeling monocytes for imaging chronic inflammation.Q37381650
Alzheimer's disease and the Blood-Brain Barrier: Past, Present and FutureQ37422795
Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disordersQ37814088
Noninvasive cell-tracking methodsQ37938642
Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activityQ38166592
Adenosine receptor PET imaging in human brainQ38245133
Astrocyte reactivity and reactive astrogliosis: costs and benefitsQ38257345
A review of the neuro- and systemic inflammatory responses in post concussion symptoms: Introduction of the "post-inflammatory brain syndrome" PIBS.Q38367319
Immune attack: the role of inflammation in Alzheimer disease.Q38492631
The immunomodulatory oligodendrocyteQ38596122
Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and strokeQ38623025
Assessing brain immune activation in psychiatric disorders: clinical and preclinical PET imaging studies of the 18-kDa translocator proteinQ40965410
Direct absolute quantification of metabolites in the human brain with in vivo localized proton spectroscopyQ41102314
In vivo analysis of neuroinflammation in the late chronic phase after experimental strokeQ41378245
Multinuclear NMR studies on the energy metabolism of glial and neuronal cellsQ41587105
Elevated subcortical choline metabolites in cognitively and clinically asymptomatic HIV+ patientsQ41618855
P2507corrigendum / erratumCorrection to In Vivo Imaging of Human NeuroinflammationQ88511238
P433issue4
P921main subjectinflammationQ101991
neuronitisQ17157137
P304page(s)470-483
P577publication date2016-03-17
P1433published inACS Chemical NeuroscienceQ2819059
P1476titleIn Vivo Imaging of Human Neuroinflammation
P478volume7

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