Iron in chronic brain disorders: imaging and neurotherapeutic implications

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Iron in chronic brain disorders: imaging and neurotherapeutic implications is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1025635610
P356DOI10.1016/J.NURT.2007.05.006
P932PMC publication ID1963417
P698PubMed publication ID17599703
P5875ResearchGate publication ID6237316

P2093author name stringAshish Arora
Rohit Bakshi
Mohit Neema
S Scott Panter
James Stankiewicz
Courtney E Batt
P2860cites workHereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndromeQ24562778
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndromeQ28210032
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysisQ28290519
Iron, brain ageing and neurodegenerative disordersQ29615656
MRI evaluation of basal ganglia ferritin iron and neurotoxicity in Alzheimer's and Huntingon's diseaseQ30600007
Magnetic resonance imaging of brain ironQ30773535
Differential diagnosis of Parkinson's disease and atypical parkinsonian disorders by magnetic resonance imagingQ30798409
Unraveling the Hallervorden-Spatz syndrome: pantothenate kinase-associated neurodegeneration is the nameQ30884537
Imaging iron stores in the brain using magnetic resonance imagingQ30983609
Quantitative MR imaging R2 relaxometry in elderly participants reporting memory lossQ31032545
Magnetic resonance imaging of iron deposition in neurological disordersQ31086982
Superficial siderosis: a case report and review of the literatureQ31089897
T1- and T2-based MRI measures of diffuse gray matter and white matter damage in patients with multiple sclerosisQ31108861
Redox-active iron mediates amyloid-beta toxicityQ31967419
Iron metabolism in Parkinsonian syndromesQ33248678
Potential sources of increased iron in the substantia nigra of parkinsonian patientsQ33259219
Glycochelates and the etiology of diabetic peripheral neuropathyQ33864190
In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imagingQ33886369
Cardiotoxicity of chemotherapeutic agents: incidence, treatment and preventionQ33903066
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.Q34082498
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia diseaseQ34083035
The physiopathological significance of ceruloplasmin. A possible therapeutic approach.Q34099972
Brain iron homeostasis.Q34173240
Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoringQ34200598
Do alterations in glutathione and iron levels contribute to pathology associated with Parkinson's disease?Q34202970
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trialQ34283745
Vitamin E and donepezil for the treatment of mild cognitive impairmentQ34411313
Use of desferrioxamine in the treatment of aceruloplasminemiaQ34419336
Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitisQ34529405
A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated tau of Alzheimer's diseaseQ34530632
Prediction of longitudinal brain atrophy in multiple sclerosis by gray matter magnetic resonance imaging T2 hypointensityQ34537576
Deep grey matter "black T2" on 3 tesla magnetic resonance imaging correlates with disability in multiple sclerosisQ34624009
Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitisQ34649942
Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells.Q34744746
Iron misregulation in the brain: a primary cause of neurodegenerative disordersQ35172307
The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategyQ35545150
Iron and Parkinson's Disease: Chelators to the Rescue?Q35556960
The free radical hypothesis in idiopathic parkinsonism: evidence against itQ35626740
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron effluxQ35632453
Novel inhibitors of iron-dependent lipid peroxidation for neurodegenerative disordersQ35753865
Iron and oxygen radicals in brainQ35753872
Iron metabolism and the IRE/IRP regulatory system: an updateQ35754458
Heme oxygenase-1: transducer of pathological brain iron sequestration under oxidative stressQ35754477
Oxidative stress and redox-active iron in Alzheimer's diseaseQ35754505
Hereditary causes of disturbed iron homeostasis in the central nervous systemQ35754524
Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasisQ35754529
Novel chelators for central nervous system disorders that involve alterations in the metabolism of iron and other metal ions.Q35754533
Brain MRI in neurodegeneration with brain iron accumulation with and without PANK2 mutations.Q36177188
Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agentQ36349617
Echo-spacing optimization for the simultaneous measurement of reversible (R2') and irreversible (R2) transverse relaxation ratesQ36447501
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during agingQ36449196
A proposed dual role of neuromelanin in the pathogenesis of Parkinson's diseaseQ36618897
Advances in the treatment of Parkinson's diseaseQ36720216
Regional metal concentrations in Parkinson's disease, other chronic neurological diseases, and control brainsQ46915316
Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeysQ46916058
Evidence for low molecular weight, non-transferrin-bound iron in rat brain and cerebrospinal fluidQ47276775
MRI evaluation of the basal ganglia size and iron content in patients with Parkinson's diseaseQ47376890
Hereditary ferritinopathy: a novel mutation, its cellular pathology, and pathogenetic insightsQ47813038
Desferrioxamine suppresses experimental allergic encephalomyelitis induced by MBP in SJL miceQ47969552
In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI.Q48149774
Increased iron in the dentate nucleus of patients with Friedrich's ataxiaQ48166308
Isoforms of ferritin have a specific cellular distribution in the brainQ48167065
Increased nigral iron content in postmortem parkinsonian brainQ48182830
T1 and T2 in the brain of healthy subjects, patients with Parkinson disease, and patients with multiple system atrophy: relation to iron contentQ48220896
Reduced signal intensity on MR images of thalamus and putamen in multiple sclerosis: increased iron content?Q48225776
MRI evaluation of brain iron in earlier- and later-onset Parkinson's disease and normal subjectsQ48228911
MR imaging of human brain at 3.0 T: preliminary report on transverse relaxation rates and relation to estimated iron contentQ48235045
Treatment of symptomatic heterozygous aceruloplasminemia with oral zinc sulphateQ48269852
Inhibition of iron-dependent and ischemia-induced brain damage by the alpha-tocopherol analogue MDL 74,722.Q48299567
T2 relaxation time in patients with Parkinson's diseaseQ48310814
Field dependent transverse relaxation rate increase may be a specific measure of tissue iron storesQ48311426
Iron deposits in the central nervous system of SJL mice with experimental allergic encephalomyelitisQ48319417
Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from alzheimer's disease patientsQ48326834
MRI of brain ironQ48328038
Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOEQ48328637
Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts.Q48346436
Clinical features and natural history of neuroferritinopathy caused by the FTL1 460InsA mutationQ48349192
MRI in chronic toluene abuse: low signal in the cerebral cortex on T2-weighted imagesQ48380452
Brain trace elements in Alzheimer's diseaseQ48401098
Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalanceQ48443119
Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosisQ48450463
Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain.Q48453211
Biological significance of iron-related magnetic resonance imaging changes in the brainQ48461384
Neuromelanin and iron in human locus coeruleus and substantia nigra during aging: consequences for neuronal vulnerabilityQ48508937
Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicityQ48524379
Magnetic field correlation imagingQ48539996
Antioxidant responses of cortex neurons to iron loading.Q48574595
Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethyl starch-conjugated deferoxamineQ48590757
Brain ferritin iron may influence age- and gender-related risks of neurodegenerationQ48606069
Deep gray matter hypointensity patterns with aging in healthy adults: MR imaging at 1.5 T.Q48612954
Iron deposits in multiple sclerosis and Alzheimer's disease brainsQ48682014
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative StudyQ48725577
The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neuronsQ48753360
MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosisQ48825761
In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damageQ48829730
FLAIR MRI of striatonigral degenerationQ48887180
Magnetic resonance imaging of corticobasal degenerationQ48904009
Iron deposits surrounding multiple sclerosis plaques.Q48917061
MR imaging of cerebral cortical involvement in aceruloplasminemia.Q48972880
Method for image-based measurement of the reversible and irreversible contribution to the transverse-relaxation rateQ49045067
Correlation of R2 with total iron concentration in the brains of rhesus monkeys.Q49120510
The pathogenesis of superficial siderosis of the central nervous system.Q50527592
The effect of age on the non-haemin iron in the human brain.Q51318963
MR detection of brain ironQ36755391
Hereditary caeruloplasmin deficiency: clinicopathological study of a patientQ36834658
In vivo measurement of T2 distributions and water contents in normal human brainQ36839935
Theory and application of static field inhomogeneity effects in gradient-echo imaging.Q36852458
Oxidative stress as a cause of Parkinson's diseaseQ37003217
A multicenter trial on the efficacy of using tirilazad mesylate in cases of head injury.Q40840968
The possible role of iron in the etiopathology of Parkinson's diseaseQ40868666
Relationship of iron to oligodendrocytes and myelinationQ41087116
Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's diseaseQ41117111
Inhibition of allergic encephalomyelitis by the iron chelating agent desferrioxamine: differential effect depending on type of sensitizing encephalitogenQ41251425
Oxidative stress and the pathogenesis of Parkinson's diseaseQ41262986
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in miceQ41593145
Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agentsQ41679218
Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen speciesQ41959326
Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patientsQ41981840
Decreased ferritin levels in brain in Parkinson's diseaseQ42000755
Cellular distribution of transferrin, ferritin, and iron in normal and aged human brainsQ42477389
Toluene abuse: physical basis for hypointensity of the basal ganglia on T2-weighted MR imagesQ42493486
Antioxidant treatment of patients with Friedreich ataxia: four-year follow-upQ42653222
Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritinQ42796062
Palatal tremor and cognitive decline in neuroferritinopathyQ43045073
Effects of an extracellular metal chelator on neurovascular function in diabetic ratsQ43622537
T(2) relaxation rate of basal ganglia and cortex in patients with beta-thalassaemia majorQ43627695
Proinflammatory cytokines promote glial heme oxygenase-1 expression and mitochondrial iron deposition: implications for multiple sclerosisQ43627953
Iron chelation improves endothelial function in patients with coronary artery disease.Q43636907
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.Q43638880
Iron on the brainQ43692149
Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegenerationQ43735211
Dextran-coupled deferoxamine improves outcome in a murine model of head injuryQ43898793
Aceruloplasminemia: new clinical, pathophysiological and therapeutic insightsQ44014364
A non-essential function for yeast frataxin in iron-sulfur cluster assemblyQ44159145
Use of allopurinol and deferoxamine in cellular protection during ischemiaQ44205743
Blood letting in high-ferritin type 2 diabetes: effects on vascular reactivityQ44231054
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's diseaseQ44386905
Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitisQ44554584
T2 values in the human brain: comparison with quantitative assays of iron and ferritinQ44583884
The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in experimental autoimmune encephalomyelitisQ44695275
Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in ratsQ44697081
Nutritional iron deprivation attenuates kainate-induced neurotoxicity in rats: implications for involvement of iron in neurodegenerationQ44856759
The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic miceQ45090946
Iron accumulation in the basal ganglia following severe ischemic-anoxic insults in childrenQ46557394
Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseasesQ46682421
Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP-induced striatal dopamine depletionQ46718289
A transient treatment of hippocampal neurons with alpha-tocopherol induces a long-lasting protection against oxidative damage via a genomic actionQ46730699
Desmethyl tirilazad improves neurologic function after hypoxic ischemic brain injury in piglets.Q51399003
Deferoxamine improves spatial memory performance following experimental brain injury in rats.Q52048500
Intramuscular desferrioxamine in patients with Alzheimer's diseaseQ52098584
Assessment of relative brain iron concentrations using T2-weighted and T2*-weighted MRI at 3 Tesla.Q52371728
Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence.Q52926826
Transferrin C2, metal binding and Alzheimer's disease.Q53329063
Oxidative stress, mitochondrial respiration, and Parkinson's disease.Q53909758
Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.Q55066167
Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian BrainsQ61714001
Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration?Q69436285
The relation between brain iron and NMR relaxation times: an in vitro studyQ71438088
Iron in parkinsonian and control substantia nigra--a Mössbauer spectroscopy studyQ71438170
A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS). The RANTTAS InvestigatorsQ71477273
Suppression of hyperacute and passively transferred experimental autoimmune encephalomyelitis by the anti-oxidant, butylated hydroxyanisoleQ71586083
Imaging of brain iron by magnetic resonance: T2 relaxation at different field strengthsQ71629150
Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regionsQ71894700
Increased iron-related MRI contrast in the substantia nigra in Parkinson's diseaseQ72319648
Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis ratsQ72556738
Oral administration of the oxidant-scavenger N-acetyl-L-cysteine inhibits acute experimental autoimmune encephalomyelitisQ72755973
MR evaluation of age-related increase of brain iron in young adult and older normal malesQ73184477
Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolitesQ73317141
An MRI method for measuring T2 in the presence of static and RF magnetic field inhomogeneitiesQ73403089
The basal ganglia in haemochromatosisQ73420750
MRI T2 shortening ('black T2') in multiple sclerosis: frequency, location, and clinical correlationQ73467304
A multiple course trial of desferrioxamine in chronic progressive multiple sclerosisQ73942282
High-dose tirilazad for acute stroke (RANTTAS II). RANTTAS II InvestigatorsQ74646450
T2 hypointensity in the deep gray matter of patients with multiple sclerosis: a quantitative magnetic resonance imaging studyQ77486197
T2-weighted MRI in Parkinson's disease; substantia nigra pars compacta hypointensity correlates with the clinical scoresQ80837762
T2rho-weighted contrast in MR images of the human brainQ81054119
Determination of transverse relaxation rate for estimating iron deposits in central nervous systemQ81133314
Ceruloplasmin in neurodegenerative diseasesQ81440799
P433issue3
P304page(s)371-386
P577publication date2007-07-01
P1433published inNeurotherapeuticsQ15716631
P1476titleIron in chronic brain disorders: imaging and neurotherapeutic implications
P478volume4

Reverse relations

cites work (P2860)
Q309033533D high spectral and spatial resolution imaging of ex vivo mouse brain
Q42149772A general analysis of calibrated BOLD methodology for measuring CMRO2 responses: comparison of a new approach with existing methods
Q98205066A preliminary study of the concentration of metallic elements in the blood of patients with multiple sclerosis as measured by ICP-MS
Q26852354A review of calibrated blood oxygenation level-dependent (BOLD) methods for the measurement of task-induced changes in brain oxygen metabolism
Q46172327A serial in vivo 7T magnetic resonance phase imaging study of white matter lesions in multiple sclerosis
Q28830683Aceruloplasminemia With Psychomotor Excitement and Neurological Sign Was Improved by Minocycline (Case Report)
Q38238656Alteration of the coenzyme A biosynthetic pathway in neurodegeneration with brain iron accumulation syndromes
Q22251261Alzheimer's disease as homeostatic responses to age-related myelin breakdown
Q44564326Analysis of multiple sclerosis lesions using a fusion of 3.0 T FLAIR and 7.0 T SWI phase: FLAIR SWI.
Q33726147Application of calibrated fMRI in Alzheimer's disease
Q26779470Appraising the Role of Iron in Brain Aging and Cognition: Promises and Limitations of MRI Methods
Q49113462Assessing global and regional iron content in deep gray matter as a function of age using susceptibility mapping
Q36215968Behavioral and Neurochemical Deficits in Aging Rats with Increased Neonatal Iron Intake: Silibinin's Neuroprotection by Maintaining Redox Balance
Q35998171Blood circulating microparticle species in relapsing-remitting and secondary progressive multiple sclerosis. A case-control, cross sectional study with conventional MRI and advanced iron content imaging outcomes
Q45404273Brain iron MRI: a biomarker for amyotrophic lateral sclerosis.
Q44615797Brain iron deposition in essential tremor: a quantitative 3-Tesla magnetic resonance imaging study.
Q57260042Brain iron levels in attention-deficit/hyperactivity disorder: A pilot MRI study
Q34568633Brain iron redistribution in mesial temporal lobe epilepsy: a susceptibility-weighted magnetic resonance imaging study
Q46301002Cerebrospinal fluid transferrin levels are reduced in patients with early multiple sclerosis
Q37921764Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives
Q28580447Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response
Q34116133Correlation of putative iron content as represented by changes in R2* and phase with age in deep gray matter of healthy adults
Q48386590Deep gray matter T2 hypointensity is present in patients with clinically isolated syndromes suggestive of multiple sclerosis
Q37388227Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis
Q57911755Deep grey matter T2 hypo-intensity in patients with paediatric multiple sclerosis
Q92577571Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis
Q48023988Differential Effect of Acute Iron Overload on Oxidative Status and Antioxidant Content in Regions of Rat Brain
Q37423548Dissociation between iron accumulation and ferritin upregulation in the aged substantia nigra: attenuation by dietary restriction.
Q36508977Dopamine transporter availability in clinically normal aging is associated with individual differences in white matter integrity
Q33732997Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegeneration
Q41189468Endosome-mitochondria interactions are modulated by iron release from transferrin.
Q28731919Evaluation of brain iron content based on magnetic resonance imaging (MRI): comparison among phase value, R2* and magnitude signal intensity
Q64081176Evaluation of iron deposition in brain basal ganglia of patients with Parkinson's disease using quantitative susceptibility mapping
Q38065116Excess iron harms the brain: the syndromes of neurodegeneration with brain iron accumulation (NBIA).
Q36374574First report of co-morbidity of pantothenate kinase-associated neurodegeneration and three types of chronic hemolytic anemias.
Q50532074Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases.
Q41836301Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA).
Q43288665Getting to the "Heart" of Cardiac Disease by Decreasing Mitochondrial Iron.
Q57898104Hemoglobin as a source of iron overload in multiple sclerosis: does multiple sclerosis share risk factors with vascular disorders?
Q35243782Human brain iron mapping using atlas-based T2 relaxometry
Q40971704Imaging and quantification of iron-oxide nanoparticles (IONP) using MP-RAGE and UTE based sequences
Q33623847In vivo structural imaging of the cerebellum, the contribution of ultra-high fields
Q34543407Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease
Q48302457Increased iron accumulation occurs in the earliest stages of demyelinating disease: an ultra-high field susceptibility mapping study in Clinically Isolated Syndrome
Q34798799Inhibition of Sirtuin 2 exerts neuroprotection in aging rats with increased neonatal iron intake
Q31152127Inversion recovery ultrashort echo time magnetic resonance imaging: A method for simultaneous direct detection of myelin and high signal demonstration of iron deposition in the brain - A feasibility study
Q44443968Involvement of globus pallidus and midbrain nuclei in pantothenate kinase-associated neurodegeneration: measurement of T2 and T2* time
Q35379973Iron and neurodegeneration in multiple sclerosis
Q28388335Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Q31020168Iron deposition and inflammation in multiple sclerosis. Which one comes first?
Q48619811Iron deposition in multiple sclerosis lesions measured by susceptibility-weighted imaging filtered phase: a case control study
Q48591960Iron deposition on SWI-filtered phase in the subcortical deep gray matter of patients with clinically isolated syndrome may precede structure-specific atrophy
Q26829932Iron dysregulation in Huntington's disease
Q26771174Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping
Q36915757Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide
Q39752057Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: results of a phase II pilot trial
Q34801617Kinetics of iron import into developing mouse organs determined by a pup-swapping method
Q58587214Latent Iron Deficiency as a Marker of Negative Symptoms in Patients with First-Episode Schizophrenia Spectrum Disorder
Q38064534Limbic system pathologies associated with deficiencies and excesses of the trace elements iron, zinc, copper, and selenium.
Q38766599Longitudinal changes of cortical microstructure in Parkinson's disease assessed with T1 relaxometry
Q33941442MRI assessment of iron deposition in multiple sclerosis
Q39722043MRI findings in neuroferritinopathy
Q33345057MRI in multiple sclerosis: current status and future prospects
Q31132442MRI in multiple sclerosis: what's inside the toolbox?
Q57094839MRI-Based Quantification of Magnetic Susceptibility in Gel Phantoms: Assessment of Measurement and Calculation Accuracy
Q89938771Magnetic Resonance Imaging in Multiple Sclerosis
Q27325407Magnetic resonance imaging (MRI) to study striatal iron accumulation in a rat model of Parkinson's disease
Q36864333Magnetic resonance imaging of myelin
Q38109630Metal dyshomeostasis and inflammation in Alzheimer's and Parkinson's diseases: possible impact of environmental exposures
Q34073566Metal imaging in neurodegenerative diseases
Q48116952Metals and electrolytes in sclerotic hippocampi in patients with drug-resistant mesial temporal lobe epilepsy
Q34269043Midlife migraine and late-life parkinsonism: AGES-Reykjavik study
Q50669013Missense PANK2 mutation without "eye of the tiger" sign: MR findings in a large group of patients with pantothenate kinase-associated neurodegeneration (PKAN).
Q55383406Multi-parametric quantitative MRI reveals three different white matter subtypes.
Q57911763Multiple Sclerosis and Chronic Cerebrospinal Venous Insufficiency: The Neuroimaging Perspective
Q27023735Multiple sclerosis: molecular mechanisms and therapeutic opportunities
Q47098715Neurochemical and Behavior Deficits in Rats with Iron and Rotenone Co-treatment: Role of Redox Imbalance and Neuroprotection by Biochanin A.
Q35975904Neuroimaging in Alzheimer's disease: preclinical challenges toward clinical efficacy
Q61051564Neuroimaging in dementia
Q31166509New rapid, accurate T2 quantification detects pathology in normal-appearing brain regions of relapsing-remitting MS patients.
Q57186503Non-Carcinogenic Risk Assessment of Heavy Metals and Fluoride in Some Water Wells in the Al-Baha Region, Saudi Arabia
Q41988403On the role of physiological fluctuations in quantitative gradient echo MRI: implications for GEPCI, QSM, and SWI.
Q38124286Pathophysiology and treatment of neurodegeneration with brain iron accumulation in the pediatric population
Q34375802Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis
Q40974003Potassium as a pluripotency-associated element identified through inorganic element profiling in human pluripotent stem cells
Q47093884Quantitative Susceptibility Mapping Reveals an Association between Brain Iron Load and Depression Severity
Q36526057Quantitative Susceptibility Mapping: Contrast Mechanisms and Clinical Applications.
Q48553203Quantitative assessment of brain iron by R(2)* relaxometry in patients with clinically isolated syndrome and relapsing-remitting multiple sclerosis
Q50999549Quantitative assessment of brain iron by R2* relaxometry in patients with cervical dystonia.
Q48568405Quantitative measurement of brain iron deposition in patients with haemodialysis using susceptibility mapping
Q47906957Real-time Correction of Motion and Imager Instability Artifacts during 3D γ-Aminobutyric Acid-edited MR Spectroscopic Imaging
Q52678256Redox metals homeostasis in multiple sclerosis and amyotrophic lateral sclerosis: a review.
Q47242221Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis
Q33757630Sample size requirements for treatment effects using gray matter, white matter and whole brain volume in relapsing-remitting multiple sclerosis
Q34303664Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration
Q42448140Signal changes in cortical laminar necrosis-evidence from susceptibility-weighted magnetic resonance imaging
Q51672185Spin echo transverse relaxation and atrophy in multiple sclerosis deep gray matter: A two-year longitudinal study.
Q48553659Sub-lethal levels of amyloid β-peptide oligomers decrease non-transferrin-bound iron uptake and do not potentiate iron toxicity in primary hippocampal neurons.
Q48108134Surgical trauma induces iron accumulation and oxidative stress in a rodent model of postoperative cognitive dysfunction
Q37949887Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations
Q42454590T2 hypointensity in the deep gray matter of patients with benign multiple sclerosis
Q42454595T2' imaging indicates decreased tissue metabolism in frontal white matter of MS patients.
Q41769794Thalamic paramagnetic iron by T2* relaxometry correlates with severity of multiple sclerosis
Q37459099The Effect of Dimethyl Fumarate on Cerebral Gray Matter Atrophy in Multiple Sclerosis
Q99616848The S-nitrosylation of parkin attenuated the ubiquitination of divalent metal transporter 1 in MPP+-treated SH-SY5Y cells
Q24289511Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
Q37772026Translational research in neurology and neuroscience 2010: multiple sclerosis
Q46205383Ultra-short echo time images quantify high liver iron
Q34193600Vascular aspects of multiple sclerosis.
Q48707884White Matter Tract Injury is Associated with Deep Gray Matter Iron Deposition in Multiple Sclerosis.
Q26778937Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease

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