Albumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal stroke

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Albumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal stroke is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1028226522
P356DOI10.1203/PDR.0B013E318123F757
P698PubMed publication ID17622953

P2093author name stringRong Wang
Andre Obenaus
Beatriz Tone
Hou Rou Tian
Stephen Ashwal
Jerome Badaut
Alison Rasmussen
P2860cites workCrystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sitesQ24311737
Correlation of cerebral hypoxic-ischemic T2 changes with tissue alterations in water content and protein extravasationQ30643940
Albumin therapy of transient focal cerebral ischemia: in vivo analysis of dynamic microvascular responsesQ31047774
Diffusion-weighted magnetic resonance imaging confirms marked neuroprotective efficacy of albumin therapy in focal cerebral ischemiaQ31962510
Volume expansion during neonatal intensive care: do we know what we are doing?Q33198811
NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties.Q33896104
Binding of drugs to serum albumin (first of two parts)Q34082487
Epidemiology of perinatal strokeQ34468322
The albumin controversyQ35869313
Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in ratsQ36735367
The antioxidants of human extracellular fluidsQ37931818
Hemodilution for cerebral ischemiaQ38198963
Albumin--an important extracellular antioxidant?Q39628687
The antioxidant action of human extracellular fluids. Effect of human serum and its protein components on the inactivation of alpha 1-antiproteinase by hypochlorous acid and by hydrogen peroxideQ42011048
A direct role for serum albumin in the cellular uptake of long-chain fatty acidsQ42107847
The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke--I: Physiological responses and safety resultsQ42689955
Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in ratsQ43722578
Cortical devascularization: quantitative diffusion weighted magnetic resonance imaging and histological findingsQ43762466
Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albuminQ44187177
Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in ratsQ44660986
Brain edema and cerebrovascular permeability during cerebral ischemia in ratsQ45288349
A new model of neonatal stroke: reversible middle cerebral artery occlusion in the rat pup.Q46039670
Effects of viscosity and oxygen content on cerebral blood flow in ischemic and normal rat brainQ48116745
Blood-brain barrier disruption and exacerbation of ischemic brain edema after restoration of blood flow in experimental focal cerebral ischemiaQ48127859
The effect of high-dose albumin therapy on local cerebral perfusion after transient focal cerebral ischemia in ratsQ48399986
Transient forebrain ischemia increases the blood-brain barrier permeability for albumin in stroke-prone spontaneously hypertensive ratsQ48416233
Serial magnetic resonance imaging in a rat pup filament stroke modelQ48459869
The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke--II: neurologic outcome and efficacy analysisQ48482907
Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrierQ48594689
Effect of delayed albumin hemodilution on infarction volume and brain edema after transient middle cerebral artery occlusion in ratsQ48619614
Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in ratsQ48863137
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic windowQ49076970
Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat.Q49161928
Prevention of hypoxic-ischemic damage with dexamethasone is dependent on age and not influenced by fasting.Q51590455
The ALIAS (ALbumin In Acute Stroke) Phase III randomized multicentre clinical trial: design and progress reportQ57756939
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectblood–brain barrierQ221694
P304page(s)261-266
P577publication date2007-09-01
P1433published inPediatric ResearchQ7159215
P1476titleAlbumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal stroke
P478volume62

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cites work (P2860)
Q30670310A review of current imaging methods used in stroke research
Q37698934Experimental methods and transport models for drug delivery across the blood-brain barrier
Q36165784Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
Q26998918Mechanisms of perinatal arterial ischemic stroke
Q30712180Neuroimaging of stroke and ischemia in animal models
Q34086176Polynitroxyl albumin and albumin therapy after pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic outcome
Q38731361Predicting Transport of 3,5,6-Trichloro-2-Pyridinol Into Saliva Using a Combination Experimental and Computational Approach
Q37337439Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury
Q46264188Protective role of early aquaporin 4 induction against postischemic edema formation
Q61865389The myth of the immature barrier systems in the developing brain: role in perinatal brain injury

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