Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

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Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1053732038
P356DOI10.1186/1742-2094-9-132
P932PMC publication ID3419627
P698PubMed publication ID22709928
P5875ResearchGate publication ID227341623

P50authorRafaela Fernandes da SilvaQ52690298
P2093author name stringKarl Schaller
Jérôme Badaut
Yvan Gasche
Jean-Christophe Copin
Andrew M Fukuda
P2860cites workEffects of high cholesterol diet on gliosis in apolipoprotein E knockout mice. Implications for Alzheimer's disease and strokeQ45079952
Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunctionQ45166632
Neurodegeneration and cognitive impairment in apoE-deficient mice is ameliorated by infusion of recombinant apoE.Q46001228
Protective role of early aquaporin 4 induction against postischemic edema formationQ46264188
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo.Q46423511
Endothelial arginase II: a novel target for the treatment of atherosclerosisQ46726767
Knockdown of arginase I restores NO signaling in the vasculature of old rats.Q46870256
Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress.Q47334929
Regional difference of lipid distribution in brain of apolipoprotein E deficient miceQ48113011
Nitric oxide synthase and arginase in the rat hippocampus and the entorhinal, perirhinal, postrhinal, and temporal cortices: Regional variations and age‐related changesQ48144508
Alteration of nitric oxide synthase activity in young and aged apolipoprotein E-deficient miceQ48422156
ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakageQ48461941
Intracranial arteries of human fetuses are more resistant to hypercholesterolemia-induced fatty streak formation than extracranial arteries.Q54099170
Dysfunction of endothelial nitric oxide synthase and atherosclerosisQ28248441
Inflammation in atherosclerosisQ29547428
Albumin reduces blood-brain barrier permeability but does not alter infarct size in a rat model of neonatal strokeQ31118233
Brain water mobility decreases after astrocytic aquaporin-4 inhibition using RNA interferenceQ34714713
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient miceQ34794990
Recent advances in arginine metabolism: roles and regulation of the arginasesQ34985733
Atherosclerosis in the apolipoprotein-E-deficient mouse: a decade of progressQ35746990
Endothelial function: a critical determinant in atherosclerosis?Q35789874
The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosisQ35888589
ApoE deficiency compromises the blood brain barrier especially after injury.Q35944147
Inflammation and atherosclerosis: novel insights into plaque formation and destabilizationQ36495025
Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling.Q36678507
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.Q37391969
Diet and age interactions with regards to cholesterol regulation and brain pathogenesisQ37731946
Nitric oxide synthase inhibition and cerebrovascular regulationQ40386712
Regulation of arginase pathway in response to wall shear stressQ43234150
Expression of arginase isozymes in mouse brainQ43825253
Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampusQ44479832
Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood VesselsQ44601105
Age-related changes in nitric oxide synthase and arginase in the rat prefrontal cortexQ44794972
P407language of work or nameEnglishQ1860
P304page(s)132
P577publication date2012-06-18
P1433published inJournal of NeuroinflammationQ15716679
P1476titleIncrease of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
P478volume9

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cites work (P2860)
Q38563837A research update on the potential roles of aquaporin 4 in neuroinflammation.
Q46762520ApoE-deficient promotes blood-brain barrier disruption in experimental autoimmune encephalomyelitis via alteration of MMP-9.
Q47619892Apolipoprotein E as a novel therapeutic neuroprotection target after traumatic spinal cord injury
Q27022405Aquaporin 4: a player in cerebral edema and neuroinflammation
Q38082329Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?
Q37621077Dose-dependent induction of astrocyte activation and reactive astrogliosis in mouse brain following maternal exposure to carbon black nanoparticle.
Q37314780Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE-/- Mice
Q47553479Genetic dissection of the neuro-glio-vascular machinery in the adult brain
Q48349072Magnetic resonance imaging biomarkers of exercise-induced improvement of oxidative stress and inflammation in the brain of old high-fat-fed ApoE-/- mice.
Q30427103Mouse models to study the effect of cardiovascular risk factors on brain structure and cognition
Q34229644Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease
Q36346592Perivascular Accumulation of β-Sheet-Rich Proteins in Offspring Brain following Maternal Exposure to Carbon Black Nanoparticles
Q47632406Pretreatment with N-acetyl cysteine suppresses chronic reactive astrogliosis following maternal nanoparticle exposure during gestational period
Q33581243Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice
Q93159118The Arginase Pathway in Neonatal Brain Hypoxia-Ischemia

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