| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M004894200 |
| P698 | PubMed publication ID | 11096068 |
| P2093 | author name string | Lavin MF | |
| Lees-Miller SP | |||
| Ye R | |||
| Khanna KK | |||
| Zhou BB | |||
| Bodero A | |||
| P2860 | cites work | Linkage of ATM to cell cycle regulation by the Chk2 protein kinase | Q22008502 |
| A role for ATR in the DNA damage-induced phosphorylation of p53 | Q22008733 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45 | Q24323084 | ||
| A single ataxia telangiectasia gene with a product similar to PI-3 kinase | Q24323579 | ||
| DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product | Q24337388 | ||
| Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro | Q24656275 | ||
| Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity | Q28140338 | ||
| Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway | Q28141324 | ||
| Interaction between ATM protein and c-Abl in response to DNA damage | Q28239339 | ||
| The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species | Q28275116 | ||
| Caffeine inhibits the checkpoint kinase ATM | Q28374785 | ||
| Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
| Caspases: killer proteases | Q29616315 | ||
| Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation | Q29871427 | ||
| ATM associates with and phosphorylates p53: mapping the region of interaction | Q30175960 | ||
| Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. | Q30450287 | ||
| Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase | Q30845708 | ||
| The role of ATM in DNA damage responses and cancer | Q34489164 | ||
| Suppression of tumour development by substances derived from the diet--mechanisms and clinical implications | Q35803133 | ||
| DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis | Q36365577 | ||
| Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death | Q36366579 | ||
| Radiosensitivity in ataxia-telangiectasia: a new explanation | Q36419108 | ||
| Soy intake and cancer risk: a review of the in vitro and in vivo data | Q36737007 | ||
| Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen | Q36774702 | ||
| Cleavage and inactivation of ATM during apoptosis. | Q38321497 | ||
| Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships | Q38531960 | ||
| When is a lipid kinase not a lipid kinase? When it is a protein kinase | Q40410589 | ||
| ATM-related genes: What do they tell us about functions of the human gene? | Q40480260 | ||
| Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. | Q40482010 | ||
| DNA-dependent protein kinase acts upstream of p53 in response to DNA damage | Q41013003 | ||
| Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints | Q41063544 | ||
| The genetic defect in ataxia-telangiectasia | Q41464274 | ||
| Dietary phytoestrogens and cancer: in vitro and in vivo studies | Q41638504 | ||
| Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. | Q42508219 | ||
| Dietary effects on breast-cancer risk in Singapore | Q45047583 | ||
| The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53. | Q45345463 | ||
| Neonatal genistein chemoprevents mammary cancer. | Q53467264 | ||
| The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit | Q64389407 | ||
| Tyrosine kinase inhibition affects type 1 angiotensin II receptor internalization | Q73113750 | ||
| The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta | Q73236678 | ||
| Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells | Q73789379 | ||
| ATM: the p53 booster | Q77534913 | ||
| Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein | Q77787501 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4828-4833 | |
| P577 | publication date | 2000-11-28 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner | |
| P478 | volume | 276 |
| Q37633188 | ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib |
| Q53581072 | Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. |
| Q53598952 | Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1. |
| Q40883583 | Degradation of p53, not telomerase activation, by E6 is required for bypass of crisis and immortalization by human papillomavirus type 16 E6/E7. |
| Q28257534 | Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells |
| Q35189038 | Direct activation of ATM by resveratrol under oxidizing conditions |
| Q38335343 | Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species |
| Q44650227 | Effects of dietary flavonoids on major signal transduction pathways in human epithelial cells |
| Q100757733 | Evaluation of Tegaran Formula ZhenHua cytotoxicity against human cancer cell lines |
| Q27919628 | Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase |
| Q39010519 | Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway |
| Q40816316 | Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. |
| Q43159491 | Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest |
| Q59193360 | Isoflavones as functional food components |
| Q33210398 | Loss of RPA1 induces Chk2 phosphorylation through a caffeine-sensitive pathway |
| Q34459467 | NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells |
| Q40644947 | P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. |
| Q35894504 | Pathway-specific effect of caffeine on protection against UV irradiation-induced apoptosis in corneal epithelial cells |
| Q33197915 | Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21. |
| Q39888783 | Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage. |
| Q34114100 | Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function |
| Q36053028 | Phytoestrogens and colorectal cancer prevention. |
| Q37520990 | Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine |
| Q42062886 | Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression |
| Q40383603 | Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin |
| Q34740058 | Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding. |
| Q36015695 | Stress-induced corneal epithelial apoptosis mediated by K+ channel activation |
| Q27639080 | Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2 |
| Q35681777 | The flavonoid beverage Haelan 951 induces growth arrest and apoptosis in pancreatic carcinoma cell lines in vitro |
| Q40118357 | Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity |
| Q54383317 | Transcriptional activation of p21(WAF¹/CIP¹) is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts. |
| Q41970188 | Ultraviolet irradiation-induced K(+) channel activity involving p53 activation in corneal epithelial cells |
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