8-(Sulfostyryl)xanthines: water-soluble A2A-selective adenosine receptor antagonists.

scientific article

8-(Sulfostyryl)xanthines: water-soluble A2A-selective adenosine receptor antagonists. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0968-0896(98)00025-X
P698PubMed publication ID9681137

P50authorChrista E MüllerQ30510483
Karl-Norbert KlotzQ42882153
P2093author name stringW Frobenius
U Geis
J Sandoval-Ramírez
U Schobert
P2860cites workMolecular cloning and characterization of the human A3 adenosine receptorQ24564442
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionQ27860958
Caffeine analogs: structure-activity relationships at adenosine receptorsQ28321859
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogsQ34169391
The in vitro pharmacology of ZM 241385, a potent, non‐xanthine, A2a selective adenosine receptor antagonistQ35872902
Adenosine receptors and their modulatorsQ40777256
Adenosine receptor subtypesQ40808680
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptorsQ42204768
Penetration of adenosine antagonists into mouse brain as determined by ex vivo bindingQ42269942
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptorsQ42286480
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.Q42545166
Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonistsQ42558334
Effects of the new A2 adenosine receptor antagonist 8FB-PTP, an 8 substituted pyrazolo-triazolo-pyrimidine, on in vitro functional modelsQ42700371
Solubilities of adenosine antagonists determined by radioreceptor assayQ45843972
(E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonistsQ46418896
Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship applicationQ48467831
Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonistsQ48561677
Aza-analogs of 8-styrylxanthines as A2A-adenosine receptor antagonistsQ48686852
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: potent and selective A(2A) adenosine antagonistsQ49097634
Configurationally stable analogs of styrylxanthines as A2A adenosine receptor antagonistQ57708674
Modulation of erythropoietin production by selective adenosine agonists and antagonists in normal and anemic ratsQ71407634
In vivo characterisation of ZM 241385, a selective adenosine A2A receptor antagonistQ71444104
Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-Dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthineQ72622175
Solubility of the Xanthines, Antipyrine, and Several Derivatives in Syrup VehiclesQ72798643
Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblastsQ72885800
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)707-719
P577publication date1998-06-01
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476title8-(Sulfostyryl)xanthines: water-soluble A2A-selective adenosine receptor antagonists
P478volume6

Reverse relations

cites work (P2860)
Q42577543Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats
Q43503760Binding of [3H]MSX-2 (3-(3-hydroxypropyl)-7-methyl-8-(m-methoxystyryl)-1-propargylxanthine) to rat striatal membranes--a new, selective antagonist radioligand for A(2A) adenosine receptors
Q40169268Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists
Q45764150Computational studies of the binding modes of A 2A adenosine receptor antagonists
Q28279556Highlights on the development of A(2A) adenosine receptor agonists and antagonists
Q38768350Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration.
Q44454321Pyrimidin-8-on[2,1-f]theophylline-9-alkylcarboxylic acids amides as A1 and A2A adenosine receptor ligands
Q40647461Recent developments in the field of A2A and A3 adenosine receptor antagonists
Q45220367Receptors subtypes involved in adenosine-mediated modulation of norepinephrine release from cardiac nerve terminals
Q42321220Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats
Q46729445Synthesis and properties of a new water-soluble prodrug of the adenosine A 2A receptor antagonist MSX-2.
Q34139398Xanthines as Adenosine Receptor Antagonists

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