Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.

scientific article

Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1998PNAS...95.6037W
P356DOI10.1073/PNAS.95.11.6037
P932PMC publication ID27581
P698PubMed publication ID9600913
P5875ResearchGate publication ID235609148

P2093author name stringWu H
Smith H
Beuerlein G
Huse WD
Watkins JD
Lee BA
Nie Y
Hensler M
P2860cites workPurification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectinQ24301078
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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vesselsQ29619679
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Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factorQ34346157
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Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune systemQ36382524
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Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesisQ36689786
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Mechanisms of angiogenesisQ38173605
Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solventsQ38359408
Unusual distributions of amino acids in complementarity-determining (hypervariable) segments of heavy and light chains of immunoglobulins and their possible roles in specificity of antibody-combining sitesQ41295516
Kinetic maturation of an immune responseQ42018143
Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogenQ43108382
The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunitQ44542390
Basic FGF and TGF-beta differentially modulate integrin expression of human microvascular endothelial cellsQ46376070
Antibody-antigen interactions: contact analysis and binding site topography.Q47628744
Application of a filamentous phage pVIII fusion protein system suitable for efficient production, screening, and mutagenesis of F(ab) antibody fragments.Q54667440
AngiogenesisQ67897095
Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sitesQ68860374
Canonical structures for the hypervariable regions of immunoglobulinsQ69450418
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)6037-6042
P577publication date1998-05-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.
P478volume95

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