Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter

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Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter is …
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scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(01)02192-5
P698PubMed publication ID11240128

P50authorSusan M EganQ38318359
P2093author name stringRuiz R
Ramos JL
Egan SM
P2860cites workSolution structure of the activator contact domain of the RNA polymerase alpha subunitQ27729311
Transcription activation by catabolite activator protein (CAP)Q28146199
Roles of cyclic AMP receptor protein and the carboxyl-terminal domain of the alpha subunit in transcription activation of the Escherichia coli rhaBAD operonQ30878909
Transcription activation at Class II CRP-dependent promoters: identification of determinants in the C-terminal domain of the RNA polymerase alpha subunit.Q33888985
Cra-dependent transcriptional activation of the icd gene of Escherichia coli.Q33991145
Domain organization of RNA polymerase alpha subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding.Q34334031
Purification and regulatory properties of MarA protein, a transcriptional activator of Escherichia coli multiple antibiotic and superoxide resistance promotersQ35599799
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replicationQ35606299
Amino acid residues in the alpha-subunit C-terminal domain of Escherichia coli RNA polymerase involved in activation of transcription from the mtr promoterQ35631103
Role of the RNA polymerase alpha subunit in transcription activationQ35658504
Suppressor mutations in rpoA suggest that OmpR controls transcription by direct interaction with the alpha subunit of RNA polymeraseQ36241595
Functional map of the alpha subunit of Escherichia coli RNA polymerase: two modes of transcription activation by positive factorsQ37604008
Role of the RNA polymerase alpha subunits in MetR-dependent activation of metE and metH: important residues in the C-terminal domain and orientation requirements within RNA polymeraseQ39585829
The TACAN4TGCA motif upstream from the -35 region in the sigma70-sigmaS-dependent Pm promoter of the TOL plasmid is the minimum DNA segment required for transcription stimulation by XylS regulatorsQ39843390
Function of the C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase in basal expression and integration host factor-mediated activation of the early promoter of bacteriophage MuQ39844110
Transcriptional control of the multiple catabolic pathways encoded on the TOL plasmid pWW53 of Pseudomonas putida MT53Q39846763
Mutations affecting two adjacent amino acid residues in the alpha subunit of RNA polymerase block transcriptional activation by the bacteriophage P2 Ogr proteinQ39899524
Evolutionary conservation of genes coding for meta pathway enzymes within TOL plasmids pWW0 and pWW53.Q39964378
Transposon mutagenesis analysis of meta-cleavage pathway operon genes of the TOL plasmid of Pseudomonas putida mt-2Q39965774
The Escherichia coli RNA polymerase alpha subunit: structure and functionQ40445593
Transcriptional control of the Pseudomonas TOL plasmid catabolic operons is achieved through an interplay of host factors and plasmid-encoded regulatorsQ41620651
Transcription activation at Escherichia coli promoters dependent on the cyclic AMP receptor protein: effects of binding sequences for the RNA polymerase alpha-subunitQ42016331
Transcription activation by the bacteriophage Mu Mor protein requires the C-terminal regions of both alpha and sigma70 subunits of Escherichia coli RNA polymeraseQ43601482
Ambidextrous transcriptional activation by SoxS: requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genesQ48067417
A comparison of the multiple alleles of xylS carried by TOL plasmids pWW53 and pDK1 and its implications for their evolutionary relationshipQ48129991
The RNA polymerase alpha subunit carboxyl-terminal domain is required for both basal and activated transcription from the alkA promoter.Q54563903
Chromosomal insertion of the entire Escherichia coli lactose operon, into two strains of Pseudomonas, using a modified mini-Tn5 delivery system.Q54570429
Location, structure, and function of the target of a transcriptional activator protein.Q54622283
Escherichia coli rpoA mutation which impairs transcription of positively regulated systemsQ54689579
Identification of a subunit assembly domain in the alpha subunit of Escherichia coli RNA polymerase.Q54699439
Mutational analysis of the highly conserved C-terminal residues of the XylS protein, a member of the AraC family of transcriptional regulatorsQ57340422
Critical Nucleotides in the Upstream Region of the XylS-dependent TOLmeta-Cleavage Pathway Operon Promoter as Deduced from Analysis of MutantsQ57340435
Identification of a cis-acting Sequence within the Pm Promoter of the TOL Plasmid which Confers XylS-mediated Responsiveness to Substituted BenzoatesQ57936346
Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRPQ62746930
The rpoA341 allele of Escherichia coli specifically impairs the transcription of a group of positively-regulated operonsQ67238022
DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architectureQ70888683
P433issue3
P407language of work or nameEnglishQ1860
P1104number of pages5
P304page(s)207-211
P577publication date2001-03-01
P1433published inFEBS LettersQ1388051
P1476titleInteractions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter
P478volume491

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cites work (P2860)
Q39524366AraC-XylS database: a family of positive transcriptional regulators in bacteria
Q35880920Bacterial transcriptional regulators for degradation pathways of aromatic compounds
Q36648589Differences in the mechanism of the allosteric l-rhamnose responses of the AraC/XylS family transcription activators RhaS and RhaR.
Q34436978Growing repertoire of AraC/XylS activators
Q29346604H-NS binding and repression of the ctx promoter in Vibrio cholerae
Q39749137Leucines 193 and 194 at the N-terminal domain of the XylS protein, the positive transcriptional regulator of the TOL meta-cleavage pathway, are involved in dimerization
Q39694798Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter
Q37831982Positively regulated bacterial expression systems.
Q58124900Prospects for Exploiting Bacteria for Bioremediation of Metal Pollution
Q42670941RNA polymerase holoenzymes can share a single transcription start site for the Pm promoter. Critical nucleotides in the -7 to -18 region are needed to select between RNA polymerase with sigma38 or sigma32.
Q42991149Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pm promoter
Q43829905Residues 137 and 153 at the N terminus of the XylS protein influence the effector profile of this transcriptional regulator and the sigma factor used by RNA polymerase to stimulate transcription from its cognate promoter
Q41893759Roles of effectors in XylS-dependent transcription activation: intramolecular domain derepression and DNA binding
Q40752789Sequential XylS-CTD binding to the Pm promoter induces DNA bending prior to activation
Q42779814The C-terminal domain of the Escherichia coli RNA polymerase alpha subunit plays a role in the CI-dependent activation of the bacteriophage lambda pM promoter
Q44002052XylS activator and RNA polymerase binding sites at the Pm promoter overlap

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