Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7.

scientific article

Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.274.52.37461
P698PubMed publication ID10601320

P50authorThomas LüscherQ62560161
P2093author name stringFujii T
Oemar BS
Nakaki T
Tanner FC
Hishikawa K
P2860cites workWISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumorsQ22008485
Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivoQ24554513
Expression of the Elm1 gene, a novel gene of the CCN (connective tissue growth factor, Cyr61/Cef10, and neuroblastoma overexpressed gene) family, suppresses In vivo tumor growth and metastasis of K-1735 murine melanoma cellsQ24647453
Caspase-14 is a novel developmentally regulated proteaseQ28287021
Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosisQ28296478
A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cellsQ28379602
Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosisQ28610861
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosisQ29614983
Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10Q33236833
The modular architecture of a new family of growth regulators related to connective tissue growth factorQ34306420
Relationship between tamoxifen-induced transforming growth factor beta 1 expression, cytostasis and apoptosis in human breast cancer cellsQ36081748
Transcriptional down regulation of the nov proto-oncogene in fibroblasts transformed by p60v-srcQ36557011
Human connective tissue growth factor is expressed in advanced atherosclerotic lesionsQ36849010
Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.Q37359272
Inhibition by transforming growth factor (34-43)-alpha, a TGF-alpha antagonist, of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar ratsQ39709886
RARalpha antagonist Ro 41-5253 inhibits proliferation and induces apoptosis in breast-cancer cell linesQ41011313
Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8).Q41029521
Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cellsQ41030261
ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell lineQ41065646
Transforming growth factor-beta 1 induces growth inhibition of a human medullary thyroid carcinoma cell line despite an increase in steady state c-myc messenger ribonucleic acid levelsQ41431171
Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitroQ41530456
Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2.Q41559408
Connective tissue growth factor. Friend or foe?Q41596354
Significant Correlation Between Connective Tissue Growth Factor Gene Expression and Skin Sclerosis in Tissue Sections from Patients with Systemic SclerosisQ41679291
Basic fibroblast growth factor downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells.Q42832716
P433issue52
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
apoptotic processQ14599311
connective tissueQ25615
cancer cell lineQ23058136
P304page(s)37461-37466
P577publication date1999-12-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleConnective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7.
P478volume274

Reverse relations

cites work (P2860)
Q42917229A sticky situation: CCN1 promotes both proliferation and apoptosis of cancer cells
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Q38290402Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells
Q40586177Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer.
Q37081505Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis?
Q37275225Bullatacin triggered ABCB1-overexpressing cell apoptosis via the mitochondrial-dependent pathway.
Q34537740CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins
Q36119192CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.
Q24684506CCN5 is a growth arrest-specific gene that regulates smooth muscle cell proliferation and motility
Q36621912CTGF (IGFBP-rP2) is specifically expressed in malignant lymphoblasts of patients with acute lymphoblastic leukaemia (ALL).
Q47905387CTGF and apoptosis in mouse osteocytes induced by tooth movement
Q36059683CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.
Q40765291CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK).
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Q24805678Styrylpyrone Derivative (SPD) induces apoptosis in a caspase-7-dependent manner in the human breast cancer cell line MCF-7
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Q40243666Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

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