Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis

scientific article published on 23 March 2011

Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/IJO.2011.985
P932PMC publication ID3711677
P698PubMed publication ID21455569
P5875ResearchGate publication ID50940742

P50authorBeth KarlanQ95982319
P2093author name stringH Phillip Koeffler
Karen M Lyons
Dong Yin
Daning Lu
James O'Kelly
Jay Vadgama
Amanda Leiter
Wenwen Chien
Julia Sohn
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In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell typeQ28244685
Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulationQ28291719
The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycansQ28578872
A multigenic program mediating breast cancer metastasis to boneQ29614308
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Proviral Rearrangements and Overexpression of a New Cellular Gene (nov) in Myeloblastosis-Associated Virus Type 1-Induced NephroblastomasQ31159804
Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7.Q33179316
A novel variant of WISP1 lacking a Von Willebrand type C module overexpressed in scirrhous gastric carcinomaQ34092531
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.Q34105855
Integrin activation controls metastasis in human breast cancerQ34107054
Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasisQ34302672
Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexesQ34429805
Functional domains of CCN1 (Cyr61) regulate breast cancer progression.Q34788640
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CCN proteins: multifunctional signalling regulatorsQ35629272
Integrins in mammary gland development and differentiation of mammary epitheliumQ35676230
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-betaQ36663630
Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional proteinQ37144234
CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathwayQ38301101
A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor geneQ38359426
Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.Q39863143
CTGF enhances migration and MMP-13 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cellsQ39870517
Alternative splicing of Cyr61 is regulated by hypoxia and significantly changed in breast cancerQ39879649
Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancerQ40260972
Proteolysis of CCN1 by plasmin: functional implicationsQ40355376
Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiationQ40429853
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Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factorQ48046112
Suppression of cell proliferation and signaling transduction by connective tissue growth factor in non-small cell lung cancer cells.Q51153671
Expression of connective tissue growth factor mRNA in the fibrous stroma of mammary tumorsQ73169436
A very private TGF-beta receptor embraceQ80614706
Abundant retention and release of connective tissue growth factor (CTGF/CCN2) by plateletsQ81144479
TGF-beta and cancerQ81484456
P433issue6
P921main subjectconnective tissueQ25615
cell migrationQ189092
angiogenesisQ539568
P304page(s)1741-1747
P577publication date2011-03-23
P1433published inInternational Journal of OncologyQ6051527
P1476titleExpression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis
P478volume38

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cites work (P2860)
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