An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation.

scientific article published on 2 December 2013

An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONC.2013.515
P932PMC publication ID6662585
P698PubMed publication ID24292671
P5875ResearchGate publication ID259110321

P50authorMichael BoettcherQ52431475
Gordon B. MillsQ28086262
P2093author name stringJ Wolf
F Zhang
K Müller-Decker
C Flechtenmacher
J D Hoheisel
M Shahmoradgoli
P2860cites workEfficient tumour formation by single human melanoma cellsQ24648938
The epithelial-mesenchymal transition generates cells with properties of stem cellsQ24650786
The basics of epithelial-mesenchymal transitionQ24652992
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Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohortsQ25257621
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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
SALL1, the gene mutated in Townes-Brocks syndrome, encodes a transcriptional repressor which interacts with TRF1/PIN2 and localizes to pericentromeric heterochromatinQ28212622
Regulation and function of Spalt proteins during animal developmentQ28236610
Identification of selective inhibitors of cancer stem cells by high-throughput screeningQ28255115
Sall1 Regulates Embryonic Stem Cell Differentiation in Association with NanogQ28592145
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathwaysQ29615855
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cellsQ29617991
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma modelQ33693027
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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancerQ33933172
Sall1-dependent signals affect Wnt signaling and ureter tip fate to initiate kidney developmentQ34080638
SALL1 mutations in Townes-Brocks syndrome and related disordersQ34096518
Tazarotene-induced gene 1 (TIG1) expression in prostate carcinomas and its relationship to tumorigenicityQ34121773
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancerQ34345765
Association between tumorigenic potential and the fate of cancer cells in a syngeneic melanoma modelQ34692759
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progressionQ35029475
Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.Q35612241
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapyQ36678657
Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesisQ37013806
EMT: when epithelial cells decide to become mesenchymal-like cellsQ37504554
Genomewide scan for loss of heterozygosity and chromosomal amplification in breast carcinoma using single-nucleotide polymorphism arraysQ37678142
Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine.Q39149769
Expression of the class II tumor suppressor gene RIG1 is directly regulated by p53 tumor suppressor in cancer cell linesQ39344280
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtypeQ39523158
Bmi1 is essential in Twist1-induced epithelial–mesenchymal transitionQ39659307
Differential expression of moesin in breast cancers and its implication in epithelial-mesenchymal transition.Q42503876
Cyr61 promotes breast tumorigenesis and cancer progressionQ44224235
Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.Q48698068
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue33
P407language of work or nameEnglishQ1860
P304page(s)4273-4278
P577publication date2013-12-02
P1433published inOncogeneQ1568657
P1476titleAn in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation
P478volume33

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cites work (P2860)
Q33623668An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter
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