| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1517/13543784.9.10.2351 |
| P698 | PubMed publication ID | 11060812 |
| P2093 | author name string | R Goldschmidt | |
| M J Macielag | |||
| P2860 | cites work | Molecular characterization of two-component systems of Helicobacter pylori | Q24524178 |
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| NMR structure of activated CheY | Q27621814 | ||
| Structure of the Escherichia coli response regulator NarL | Q27733319 | ||
| The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor | Q27734689 | ||
| Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY | Q27748790 | ||
| Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain | Q27748852 | ||
| Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway | Q27759197 | ||
| Structure of CheA, a signal-transducing histidine kinase | Q27766893 | ||
| A two-component system that regulates an osmosensing MAP kinase cascade in yeast | Q27930757 | ||
| Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor. | Q27930940 | ||
| Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis | Q28776658 | ||
| Cell cycle control by an essential bacterial two-component signal transduction protein | Q29346643 | ||
| Signal transduction in bacteria: molecular mechanisms of stimulus-response coupling | Q33538598 | ||
| Taking the plunge. Terminal differentiation in Dictyostelium | Q33543975 | ||
| High energy exchange: proteins that make or break phosphoramidate bonds | Q33658324 | ||
| Phosphorelay signal transduction: the emerging family of plant response regulators | Q33763349 | ||
| Helicobacter pylori possesses two CheY response regulators and a histidine kinase sensor, CheA, which are essential for chemotaxis and colonization of the gastric mucosa | Q34003888 | ||
| Effects of Enterococcus faecalis fsr genes on production of gelatinase and a serine protease and virulence | Q34004200 | ||
| The response regulator PhoP is important for survival under conditions of macrophage-induced stress and virulence in Yersinia pestis | Q34004738 | ||
| A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence. | Q34286908 | ||
| The ethylene hormone response in Arabidopsis: a eukaryotic two-component signaling system | Q34306891 | ||
| Protein aspartate phosphatases control the output of two-component signal transduction systems | Q34402585 | ||
| Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence | Q34984682 | ||
| Negative control of bacterial DNA replication by a cell cycle regulatory protein that binds at the chromosome origin | Q35669148 | ||
| An essential, multicomponent signal transduction pathway required for cell cycle regulation in Caulobacter | Q35863693 | ||
| Bacterial infection as assessed by in vivo gene expression | Q35966527 | ||
| Antibacterial agents that inhibit two-component signal transduction systems | Q36069845 | ||
| Inhibitors of two-component signal transduction systems: inhibition of alginate gene activation in Pseudomonas aeruginosa | Q36083674 | ||
| Global GacA-steered control of cyanide and exoprotease production in Pseudomonas fluorescens involves specific ribosome binding sites | Q36707819 | ||
| Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators | Q36774475 | ||
| Use of recombinase gene fusions to identify Vibrio cholerae genes induced during infection | Q36805445 | ||
| AlgR2 is an ATP/GTP-dependent protein kinase involved in alginate synthesis by Pseudomonas aeruginosa | Q36914623 | ||
| Large-scale isolation of candidate virulence genes of Pseudomonas aeruginosa by in vivo selection. | Q37341926 | ||
| Covalent modification of the glnG product, NRI, by the glnL product, NRII, regulates the transcription of the glnALG operon in Escherichia coli | Q37394494 | ||
| Macrophage killing is an essential virulence mechanism of Salmonella typhimurium | Q37632625 | ||
| Hyphal development in Neurospora crassa: involvement of a two-component histidine kinase | Q37655365 | ||
| A region of the transmembrane regulatory protein ToxR that tethers the transcriptional activation domain to the cytoplasmic membrane displays wide divergence among Vibrio species | Q38316647 | ||
| Structural and genetic analysis of the bvg locus in Bordetella species | Q38333115 | ||
| vanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174. | Q39474153 | ||
| Construction and characterization of an agr deletion mutant of Staphylococcus epidermidis | Q39514344 | ||
| PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance | Q39843622 | ||
| A small protein that mediates the activation of a two-component system by another two-component system | Q40370371 | ||
| PhoP/Q regulated genes in Salmonella typhi identification of melittin sensitive mutants | Q40654923 | ||
| phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers. | Q40668237 | ||
| Substituted salicylanilides as inhibitors of two-component regulatory systems in bacteria | Q41020835 | ||
| Construction and characterisation of a Yersinia enterocolitica O:8 ompR mutant | Q41485240 | ||
| A two-component signal-transducing system is involved in competence and penicillin susceptibility in laboratory mutants of Streptococcus pneumoniae | Q42599921 | ||
| PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance | Q42613861 | ||
| Phase variation in Bordetella pertussis by frameshift mutation in a gene for a novel two-component system | Q42641359 | ||
| The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. | Q42676857 | ||
| Stabilization of the phospho-aspartyl residue in a two-component signal transduction system in Thermotoga maritima | Q43025803 | ||
| A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active site | Q43452313 | ||
| Mechanism of membrane damage induced by the amphipathic peptides gramicidin S and melittin | Q43987660 | ||
| A genomic analysis of two-component signal transduction in Streptococcus pneumoniae | Q44768445 | ||
| A yeast protein similar to bacterial two-component regulators | Q46106065 | ||
| cis-unsaturated fatty acids specifically inhibit a signal-transducing protein kinase required for initiation of sporulation in Bacillus subtilis | Q46309599 | ||
| Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators | Q46366210 | ||
| Emergence of vancomycin tolerance in Streptococcus pneumoniae | Q47954249 | ||
| Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus | Q48014401 | ||
| PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance | Q48038471 | ||
| Isolation of CaSLN1 and CaNIK1, the genes for osmosensing histidine kinase homologues, from the pathogenic fungus Candida albicans | Q48039813 | ||
| Salmonella SsrB activates a global regulon of horizontally acquired genes | Q50120790 | ||
| Selection of bacterial virulence genes that are specifically induced in host tissues | Q50167010 | ||
| Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: pharmacophore identification based on the screening hit closantel. | Q52567484 | ||
| Genetic and physiological studies of the CiaH-CiaR two-component signal-transducing system involved in cefotaxime resistance and competence of Streptococcus pneumoniae. | Q54081069 | ||
| NMR studies of the phosphotransfer domain of the histidine kinase CheA from Escherichia coli: assignments, secondary structure, general fold, and backbone dynamics | Q54601374 | ||
| Novel streptopyrroles from Streptomyces rimosus with bacterial protein histidine kinase inhibitory and antimicrobial activities | Q73563624 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2351-2369 | |
| P577 | publication date | 2000-10-01 | |
| P1433 | published in | Expert Opinion on Investigational Drugs | Q5421208 |
| P1476 | title | Inhibitors of bacterial two-component signalling systems | |
| P478 | volume | 9 |
| Q37731045 | Anti-bacterial and Anti-biofilm Evaluation of Thiazolopyrimidinone Derivatives Targeting the Histidine Kinase YycG Protein of Staphylococcus epidermidis |
| Q39978670 | Ascochytatin, a novel bioactive spirodioxynaphthalene metabolite produced by the marine-derived fungus, Ascochyta sp. NGB4. |
| Q39457826 | Bacterial signal transduction networks via connectors and development of the inhibitors as alternative antibiotics |
| Q35917322 | Can virulence factors be viable antibacterial targets? |
| Q34274377 | Comparative transcriptomic analysis of streptococcus pseudopneumoniae with viridans group streptococci |
| Q33946287 | DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase. |
| Q33475180 | Discovery of novel inhibitors of Streptococcus pneumoniae based on the virtual screening with the homology-modeled structure of histidine kinase (VicK). |
| Q35862451 | Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell. |
| Q48157607 | Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli. |
| Q46421308 | High-throughput microplate phosphorylation assays based on DevR-DevS/Rv2027c 2-component signal transduction pathway to screen for novel antitubercular compounds |
| Q34522709 | Histidine kinases as targets for new antimicrobial agents |
| Q21194887 | Histidine protein kinases: key signal transducers outside the animal kingdom |
| Q33291875 | Identification of gene targets against dormant phase Mycobacterium tuberculosis infections |
| Q44328436 | Inhibition of the plant cytokinin transduction pathway by bacterial histidine kinase inhibitors in Catharanthus roseus cell cultures. |
| Q41811635 | Isolation and characterization of signermycin B, an antibiotic that targets the dimerization domain of histidine kinase WalK |
| Q35684970 | Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism |
| Q35056042 | Novel agents for the treatment of resistant Gram-positive infections |
| Q37276243 | Probing the roles of the two different dimers mediated by the receiver domain of the response regulator PhoB. |
| Q41874972 | Rational design of inhibitors of VirA-VirG two-component signal transduction |
| Q34823364 | Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence |
| Q36949989 | Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face |
| Q33263149 | Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections |
| Q31157461 | Targeting protein homodimerization: a novel drug discovery system |
| Q54438070 | Targeting two-component signal transduction: a novel drug discovery system. |
| Q49970485 | The FDA-approved anti-cancer drugs, streptozotocin and floxuridine, reduce the virulence of Staphylococcus aureus. |
| Q40558328 | The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases |
| Q33996907 | The effect of the potential PhoQ histidine kinase inhibitors on Shigella flexneri virulence |
| Q34792967 | Virulence- and antibiotic resistance-associated two-component signal transduction systems of Gram-positive pathogenic bacteria as targets for antimicrobial therapy |
| Q43199652 | Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth. |
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