PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance

scientific article published in March 1998

PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1046/J.1365-2958.1998.00757.X
P698PubMed publication ID9570402
P5875ResearchGate publication ID229860143

P2093author name stringGuo L
Kim K
Krueger J
Lim KB
Gunn JS
Miller SI
Hackett M
P2860cites workThe complete genome sequence of Escherichia coli K-12Q27860542
Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosisQ28303994
Resistance to host antimicrobial peptides is necessary for Salmonella virulenceQ31030619
Antibiotic peptides as mediators of innate immunityQ33987884
Antibiotic proteins of human neutrophilsQ34262671
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.Q34286908
Epithelial antibiotic induced in states of diseaseQ34433834
Transcriptional regulation of Salmonella virulence: a PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP.Q35616130
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulentQ35617117
Bacterial infection as assessed by in vivo gene expressionQ35966527
Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulenceQ36102441
Characterization of the rfc region of Shigella flexneriQ36105069
Rapid mapping in Salmonella typhimurium with Mud-P22 prophagesQ36120534
Structural characterization of the lipid A component of Bacteroides fragilis strain NCTC 9343 lipopolysaccharideQ36122299
Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophagesQ36162205
Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide geneQ36307069
Characterization of the cassette containing genes for type 3 capsular polysaccharide biosynthesis in Streptococcus pneumoniaeQ36364598
Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence inductionQ36833896
Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ.Q36852656
Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomesQ37265751
A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharideQ39757929
Two-component regulatory systems can interact to process multiple environmental signalsQ39843585
PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistanceQ39843622
Isolation and characterization of a gene, pmrD, from Salmonella typhimurium that confers resistance to polymyxin when expressed in multiple copiesQ39932313
phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers.Q40668237
Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menE gene from Escherichia coliQ42629525
Cloning and sequence of a region encoding a surface polysaccharide of Vibrio cholerae O139 and characterization of the insertion site in the chromosome of Vibrio cholerae O1.Q42639123
Ionizing groups in lipopolysaccharides of Pseudomonas cepacia in relation to antibiotic resistanceQ44104959
Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR studyQ50151855
A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cellsQ50195971
Characterization of Tn10d-Cam: a transposition-defective Tn10 specifying chloramphenicol resistanceQ50197602
Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimuriumQ50216500
Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. II. Properties of a high-frequency-transducing lysateQ50235878
Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A.Q54177184
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1171-1182
P577publication date1998-03-01
P1433published inMolecular MicrobiologyQ6895967
P1476titlePmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance
P478volume27

Reverse relations

cites work (P2860)
Q3442942610'(Z),13'(E)-heptadecadienylhydroquinone inhibits swarming and virulence factors and increases polymyxin B susceptibility in Proteus mirabilis
Q37734003A Klebsiella pneumoniae antibiotic resistance mechanism that subdues host defences and promotes virulence
Q34097875A Lactobacillus acidophilus strain of human gastrointestinal microbiota origin elicits killing of enterovirulent Salmonella enterica Serovar Typhimurium by triggering lethal bacterial membrane damage
Q30453404A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides.
Q30975949A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium
Q36479175A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis.
Q41857195A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.
Q35901144A connector of two-component regulatory systems promotes signal amplification and persistence of expression
Q34391736A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose
Q33319574A model of Salmonella colitis with features of diarrhea in SLC11A1 wild-type mice
Q33593645A neutrophil-derived anti-infective molecule: bactericidal/permeability-increasing protein
Q31167722A novel 3-deoxy-D-manno-octulosonic acid (Kdo) hydrolase that removes the outer Kdo sugar of Helicobacter pylori lipopolysaccharide
Q51118472A pharmacokinetic/pharmacodynamic model developed for the effect of colistin on Pseudomonas aeruginosa in vitro with evaluation of population pharmacokinetic variability on simulated bacterial killing.
Q24680372A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability
Q34711643A rapid one-step method for the characterization of membrane lipid remodeling in Francisella using matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry
Q42589283A sensitive liquid chromatography/mass spectrometry-based assay for quantitation of amino-containing moieties in lipid A.
Q50118677A signal transduction system that responds to extracellular iron
Q40370371A small protein that mediates the activation of a two-component system by another two-component system
Q50006546A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system
Q50913117A two-tier model of polymyxin B resistance in Burkholderia cenocepacia.
Q42035699Absence of PmrAB-mediated phosphoethanolamine modifications of Citrobacter rodentium lipopolysaccharide affects outer membrane integrity
Q31006874Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm
Q42119116Acid pH activation of the PmrA/PmrB two-component regulatory system of Salmonella enterica
Q60916150Action of Antimicrobial Peptides against Bacterial Biofilms
Q47678624Adaptation in toxic environments: comparative genomics of loci carrying antibiotic resistance genes derived from acid mine drainage waters
Q30848228Adrenaline modulates the global transcriptional profile of Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses
Q41206980Altered host immune responses to membrane vesicles from Salmonella and Gram-negative pathogens.
Q84501547An Edwardsiella tarda mutant lacking UDP-glucose dehydrogenase shows pleiotropic phenotypes, attenuated virulence, and potential as a vaccine candidate
Q28484617An allele of an ancestral transcription factor dependent on a horizontally acquired gene product
Q34482569An altered immune response, but not individual cationic antimicrobial peptides, is associated with the oral attenuation of Ara4N-deficient Salmonella enterica serovar Typhimurium in mice
Q40311426An antimicrobial peptide-resistant minor subpopulation of Photorhabdus luminescens is responsible for virulence.
Q34868635An easy, simple inexpensive test for the specific detection of Pectobacterium carotovorum subsp. carotovorum based on sequence analysis of the pmrA gene.
Q37259730An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A.
Q31006859An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor
Q33243647An outer membrane enzyme encoded by Salmonella typhimurium lpxR that removes the 3'-acyloxyacyl moiety of lipid A.
Q24654765An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli
Q35191878Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors
Q28479229Ancestral genes can control the ability of horizontally acquired loci to confer new traits
Q54230402Antibacterial activity of class I and IIa bacteriocins combined with polymyxin E against resistant variants of Listeria monocytogenes and Escherichia coli
Q37926863Antimicrobial peptides: promising alternatives to conventional antibiotics
Q38089201Antimicrobial peptides: to membranes and beyond
Q40931605ArnT proteins that catalyze the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases.
Q36315932Bacterial danger sensing
Q43718689Bacterial modification of LPS and resistance to antimicrobial peptides
Q37874201Bacterial resistance mechanisms against host defense peptides
Q37421363Bacterial sensing of antimicrobial peptides
Q36920921Bacterial strategies of resistance to antimicrobial peptides.
Q38284259Bile salts induce resistance to polymyxin in enterohemorrhagic Escherichia coli O157:H7.
Q24807172Binding of protegrin-1 to Pseudomonas aeruginosa and Burkholderia cepacia
Q38065203Biocides--resistance, cross-resistance mechanisms and assessment
Q35723413Biosynthesis, transport, and modification of lipid A.
Q39516006Brucella abortus and its closest phylogenetic relative, Ochrobactrum spp., differ in outer membrane permeability and cationic peptide resistance
Q42800237Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo
Q35987326Burkholderia mallei expresses a unique lipopolysaccharide mixture that is a potent activator of human Toll-like receptor 4 complexes
Q24559990Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides
Q41585173Cathelicidin antimicrobial peptide expression is not induced or required for bacterial clearance during salmonella enterica infection of human monocyte-derived macrophages
Q30857151Cationic antimicrobial peptide resistance in Neisseria meningitidis
Q36159546Cationic antimicrobial peptides serve as activation signals for the Salmonella Typhimurium PhoPQ and PmrAB regulons in vitro and in vivo
Q38316595Cationic peptide antimicrobials induce selective transcription of micF and osmY in Escherichia coli
Q38659316Ceftolozane-tazobactam: A new-generation cephalosporin.
Q33826394Characterization of UDP-glucose dehydrogenase and UDP-glucose pyrophosphorylase mutants of Proteus mirabilis: defectiveness in polymyxin B resistance, swarming, and virulence.
Q34353996Characterization of late acyltransferase genes of Yersinia pestis and their role in temperature-dependent lipid A variation
Q40264365Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages
Q33867080Characterization of the Escherichia coli AF/R1 pilus operon: novel genes necessary for transcriptional regulation and for pilus-mediated adherence
Q34959854Closing the loop: the PmrA/PmrB two-component system negatively controls expression of its posttranscriptional activator PmrD.
Q37410274Codependent and independent effects of nitric oxide-mediated suppression of PhoPQ and Salmonella pathogenicity island 2 on intracellular Salmonella enterica serovar typhimurium survival.
Q40672610Colistin: the phoenix arises
Q36095874Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections
Q33792343Comparative efficacy analysis of anti-microbial peptides, LL-37 and indolicidin upon conjugation with CNT, in human monocytes
Q90383488Comparison of Gene Expression Profiles of Uropathogenic Escherichia Coli CFT073 after Prolonged Exposure to Subinhibitory Concentrations of Different Biocides
Q50091022Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium
Q41435112Comprehensive structure characterization of lipid A extracted from Yersinia pestis for determination of its phosphorylation configuration
Q33842938Conflicting roles for a cell surface modification in Salmonella
Q30781626Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes
Q34408515Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance
Q42318156D-form KLKLLLLLKLK-NH2 peptide exerts higher antimicrobial properties than its L-form counterpart via an association with bacterial cell wall components
Q34590115Dam methylation participates in the regulation of PmrA/PmrB and RcsC/RcsD/RcsB two component regulatory systems in Salmonella enterica serovar Enteritidis
Q50424919Differences in the antibacterial activity of nisin and bovicin HC5 against Salmonella Typhimurium under different temperature and pH conditions.
Q34453619Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions
Q38608685Differential regulation by magnesium of the two MsbB paralogs of Shigella flexneri.
Q28493076Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues
Q47977407Effect of cold shock on lipid A biosynthesis in Escherichia coli. Induction At 12 degrees C of an acyltransferase specific for palmitoleoyl-acyl carrier protein
Q92437770Envelope stress responses: balancing damage repair and toxicity
Q41956528Escherichia coli mutants that synthesize dephosphorylated lipid A molecules.
Q33379088Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria
Q30965642Expression cloning and biochemical characterization of a Rhizobium leguminosarum lipid A 1-phosphatase
Q33622203Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases
Q42406450Extracellular loops of lipid A 3-O-deacylase PagL are involved in recognition of aminoarabinose-based membrane modifications in Salmonella enterica serovar typhimurium
Q37910758Extreme antimicrobial Peptide and polymyxin B resistance in the genus burkholderia
Q38037528Extreme antimicrobial peptide and polymyxin B resistance in the genus Burkholderia.
Q44078214Fe(III)-mediated cellular toxicity
Q37581576Flipping lipids: why an' what's the reason for?
Q38113080Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis.
Q33946946Functional cloning and characterization of a UDP- glucuronic acid decarboxylase: the pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis
Q88608576Gene expression kinetics governs stimulus-specific decoration of the Salmonella outer membrane
Q39063044Genetic Regulation of Virulence and Antibiotic Resistance in Acinetobacter baumannii
Q37204246Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium
Q34004929Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium
Q37488918Genome-wide transcriptional profiling of the Escherichia coli response to a proline-rich antimicrobial peptide
Q53298175Genomic variations between colistin-susceptible and -resistant Pseudomonas aeruginosa clinical isolates and their effects on colistin resistance.
Q33329463Glucosamine found as a substituent of both phosphate groups in Bordetella lipid A backbones: role of a BvgAS-activated ArnT ortholog
Q35300228Gut microbiota. Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation
Q34116838Helicobacter pylori versus the host: remodeling of the bacterial outer membrane is required for survival in the gastric mucosa
Q38532214Helicobacter pylori: expect the unexpected
Q50121309High-resolution NMR spectroscopy of lipid A molecules containing 4-amino-4-deoxy-L-arabinose and phosphoethanolamine substituents. Different attachment sites on lipid A molecules from NH4VO3-treated Escherichia coli versus kdsA mutants of Salmonella
Q56891272High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
Q34522709Histidine kinases as targets for new antimicrobial agents
Q34575973How do bacteria resist human antimicrobial peptides?
Q40742533Human Toll-like receptor 4 recognizes host-specific LPS modifications.
Q34259685Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium
Q34008201Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection
Q92459815Identification of Primary Antimicrobial Resistance Drivers in Agricultural Nontyphoidal Salmonella enterica Serovars by Using Machine Learning
Q30992994Identification of Proteus mirabilis mutants with increased sensitivity to antimicrobial peptides
Q33726568Identification of a bifunctional UDP-4-keto-pentose/UDP-xylose synthase in the plant pathogenic bacterium Ralstonia solanacearum strain GMI1000, a distinct member of the 4,6-dehydratase and decarboxylase family
Q35015089Identification of a functionally important loop in Salmonella typhimurium ArnT
Q37256450Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity
Q33788470Identification of cptA, a PmrA-regulated locus required for phosphoethanolamine modification of the Salmonella enterica serovar typhimurium lipopolysaccharide core
Q35103882Identification of the lipopolysaccharide modifications controlled by the Salmonella PmrA/PmrB system mediating resistance to Fe(III) and Al(III).
Q43106542Identification of undecaprenyl phosphate-beta-D-galactosamine in Francisella novicida and its function in lipid A modification
Q35550509Immunogenicity against human papillomavirus type 16 virus-like particles is strongly enhanced by the PhoPc phenotype in Salmonella enterica serovar Typhimurium
Q36018883Impact of two-component regulatory systems PhoP-PhoQ and PmrA-PmrB on colistin pharmacodynamics in Pseudomonas aeruginosa
Q35662086In Vivo Selection of Pan-Drug Resistant Acinetobacter baumannii during Antibiotic Treatment
Q24807196In silico identification and experimental validation of PmrAB targets in Salmonella typhimurium by regulatory motif detection
Q28343235In vitro antibacterial properties of pexiganan, an analog of magainin
Q92764955Inactivation of Polymyxin by Hydrolytic Mechanism
Q42022967Induction of the Cpx envelope stress pathway contributes to Escherichia coli tolerance to antimicrobial peptides
Q36760658Induction of the Yersinia pestis PhoP-PhoQ regulatory system in the flea and its role in producing a transmissible infection
Q40732234Induction of {beta}-defensin resistance in the oral anaerobe Porphyromonas gingivalis
Q33716676Inhibition of Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation by aminoarabinose membrane modification
Q33181385Inhibitors of bacterial two-component signalling systems
Q89108679Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
Q39392758Intraspecies and temperature-dependent variations in susceptibility of Yersinia pestis to the bactericidal action of serum and to polymyxin B.
Q39472156Isolation of polymyxin B-susceptible mutants of Burkholderia pseudomallei and molecular characterization of genetic loci involved in polymyxin B resistance.
Q35468441Kdo2 -lipid A: structural diversity and impact on immunopharmacology
Q33558978Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence
Q41380267LPS modification promotes maintenance of Yersinia pestis in fleas
Q35988748LPS, TLR4 and infectious disease diversity.
Q42410762Latency of the Lipid A Deacylase PagL Is Involved in Producing a Robust Permeation Barrier in the Outer Membrane of Salmonella enterica
Q36899142Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides.
Q24650951Lipid A modification systems in gram-negative bacteria
Q30717098Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitate
Q31006759Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporation
Q35925899Lipopolysaccharide Phosphorylation by the WaaY Kinase Affects the Susceptibility of Escherichia coli to the Human Antimicrobial Peptide LL-37.
Q28493092Lipopolysaccharide core phosphates are required for viability and intrinsic drug resistance in Pseudomonas aeruginosa
Q24650970Lipopolysaccharide endotoxins
Q38059703Lipopolysaccharide of Yersinia pestis, the Cause of Plague: Structure, Genetics, Biological Properties
Q33784947Live attenuated Salmonella: a paradigm of mucosal vaccines.
Q37449126Masters of conquest and pillage: Xenorhabdus nematophila global regulators control transitions from virulence to nutrient acquisition
Q26749527Mechanisms and consequences of bacterial resistance to antimicrobial peptides
Q34873405Mechanisms and fitness costs of resistance to antimicrobial peptides LL-37, CNY100HL and wheat germ histones
Q35541353Mechanisms of Antimicrobial Peptide Resistance in Gram-Negative Bacteria
Q92302854Mechanisms of Polymyxin Resistance
Q91580928Mechanisms of Salmonella pathogenesis in animal models
Q34016418Mechanisms of bacterial resistance and response to bile
Q35574562Mechanisms of heme utilization by Francisella tularensis
Q38287949Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria
Q46874955Membrane-active mechanism of LFchimera against Burkholderia pseudomallei and Burkholderia thailandensis.
Q34595514Microarray-based detection of Salmonella enterica serovar Enteritidis genes involved in chicken reproductive tract colonization.
Q36804404Modulation of hexa-acyl pyrophosphate lipid A population under Escherichia coli phosphate (Pho) regulon activation
Q41415945Molecular basis of Yersinia enterocolitica temperature-dependent resistance to antimicrobial peptides.
Q29616208Molecular basis of bacterial outer membrane permeability revisited
Q36370781Molecular characterization of the Mg2+-responsive PhoP-PhoQ regulon in Salmonella enterica
Q50124709Molecular characterization of the PmrA regulon.
Q55516047Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin.
Q92999146Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa
Q33206138Novel modification of lipid A of Francisella tularensis
Q34191665Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose
Q35746200Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidase
Q24794555Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria
Q37227443Outer membrane permeability and antibiotic resistance
Q34101511Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose
Q30656145Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, A new Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue
Q92953771Pathoadaptive Alteration of Salmonella Biofilm Formation in Response to the Gallbladder Environment
Q27003337Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems
Q36804699Pathogenicity of Yersinia pestis synthesis of 1-dephosphorylated lipid A.
Q28484797Periplasmic cleavage and modification of the 1-phosphate group of Helicobacter pylori lipid A
Q36436276Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate
Q34346283Pharmacology of polymyxins: new insights into an 'old' class of antibiotics
Q37693828Phenotypic differences between Salmonella and Escherichia coli resulting from the disparate regulation of homologous genes
Q42613861PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance
Q39510342PhoP-PhoQ-regulated loci are required for enhanced bile resistance in Salmonella spp
Q42909802PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium.
Q35598578PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients
Q36163168Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity
Q35527834Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro
Q33901939Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system.
Q33675769Phosphoglucomutase of Yersinia pestis is required for autoaggregation and polymyxin B resistance.
Q36158426Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity
Q33994345Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar typhimurium
Q40387809PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A
Q35689189PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients
Q35168891PmrD is required for modifications to escherichia coli endotoxin that promote antimicrobial resistance
Q34648509Polyamines induce resistance to cationic peptide, aminoglycoside, and quinolone antibiotics in Pseudomonas aeruginosa PAO1.
Q47986085Polymorphism of genes encoding PmrAB in colistin-resistant strains of Escherichia coli and Salmonella enterica isolated from poultry and swine
Q42043540Polymyxin B resistance and biofilm formation in Vibrio cholerae are controlled by the response regulator CarR.
Q39739730Polymyxin B resistance in El Tor Vibrio cholerae requires lipid acylation catalyzed by MsbB.
Q36960059Polymyxin B: similarities to and differences from colistin (polymyxin E).
Q36785850Polymyxin resistance of Pseudomonas aeruginosa phoQ mutants is dependent on additional two-component regulatory systems
Q38922536Polymyxin: Alternative Mechanisms of Action and Resistance.
Q92302848Polymyxins: Mode of Action
Q41548584Polysialic and colanic acids metabolism in Escherichia coli K92 is regulated by RcsA and RcsB.
Q30576597Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria
Q57441692Proteomic analysis of Pseudomonas aeruginosa grown under magnesium limitation
Q33768793Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion.
Q42545742Pseudomonas aeruginosa high-level resistance to polymyxins and other antimicrobial peptides requires cprA, a gene that is disrupted in the PAO1 strain
Q30880301Purification and mass spectrometry of six lipid A species from the bacterial endosymbiont Rhizobium etli. Demonstration of a conserved distal unit and a variable proximal portion
Q34808489Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways
Q41473930Quinolones sensitize gram-negative bacteria to antimicrobial peptides
Q42077622Reciprocal control between a bacterium's regulatory system and the modification status of its lipopolysaccharide
Q39306286Reclassification of the Specialized Metabolite Producer Pseudomonas mesoacidophila ATCC 31433 as a Member of the Burkholderia cepacia Complex
Q38081375Recognition of lipid A variants by the TLR4-MD-2 receptor complex
Q39127637Rediscovering the octapeptins.
Q43718691Regulated covalent modifications of lipid A.
Q33283833Release of the lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to the antimicrobial peptide polymyxin B in Salmonella enterica
Q34297729Removal of the outer Kdo from Helicobacter pylori lipopolysaccharide and its impact on the bacterial surface
Q37333088Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system
Q34425887Resistance to the antimicrobial peptide polymyxin requires myristoylation of Escherichia coli and Salmonella typhimurium lipid A.
Q35541277Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing
Q34999695Review: Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa.
Q36593938Role of RppA in the regulation of polymyxin b susceptibility, swarming, and virulence factor expression in Proteus mirabilis
Q34233310Role of Salmonella enterica serovar Typhimurium two-component system PreA/PreB in modulating PmrA-regulated gene transcription
Q34607140Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
Q40755880Role of lipid A acylation in Yersinia enterocolitica virulence
Q38341710S. Typhimurium strategies to resist killing by cationic antimicrobial peptides.
Q48364283Salmonella Typhimurium PagP- and UgtL-dependent resistance to antimicrobial peptides contributes to the gut colonization
Q39678359Salmonella enterica serovar typhimurium resistance to bile: identification and characterization of the tolQRA cluster
Q34007636Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivo
Q36938597Salmonella sensing of anti-microbial mechanisms to promote survival within macrophages.
Q36197324Salmonella stress management and its relevance to behaviour during intestinal colonisation and infection
Q34469853Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity
Q33704910Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity.
Q37008201Salmonellae interplay with host cells
Q37222605Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides
Q33427345Sensitization of outer-membrane mutants of Salmonella typhimurium and Pseudomonas aeruginosa to antimicrobial peptides under high pressure
Q34057453Serratia marcescens arn, a PhoP-regulated locus necessary for polymyxin B resistance.
Q50102611Signal-dependent Requirement for the Co-activator Protein RcsA in Transcription of the RcsB-regulated ugd Gene
Q43134448Silica deposition and phenotypic changes to Thermus thermophilus cultivated in the presence of supersaturated silicia
Q43071796SlyA, a MarR family transcriptional regulator, is essential for virulence in Dickeya dadantii 3937.
Q46697816Spotlight on Human LL-37, an Immunomodulatory Peptide with Promising Cell-Penetrating Properties.
Q39537077Stages of polymyxin B interaction with the Escherichia coli cell envelope
Q24672531Stimulus perception in bacterial signal-transducing histidine kinases
Q35098861Striking complexity of lipopolysaccharide defects in a collection of Sinorhizobium meliloti mutants
Q27681447Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria
Q27671965Structural basis for the interaction of lipopolysaccharide with outer membrane protein H (OprH) from Pseudomonas aeruginosa
Q34312726Structural characterization of bacterial lipopolysaccharides with mass spectrometry and on- and off-line separation techniques
Q34677348Structural insights into Escherichia coli polymyxin B resistance protein D with X-ray crystallography and small-angle X-ray scattering
Q24596697Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis
Q24630632Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance
Q40677648Structure of the Escherichia coli ArnA N-formyltransferase domain in complex with N(5) -formyltetrahydrofolate and UDP-Ara4N.
Q44874218Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds
Q34010143Structure--activity relationships of polymyxin antibiotics
Q35592652Structures of Bacteroides fragilis uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (BfLpxA)
Q33825974Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14
Q50041674Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium.
Q33721943Successive emergence of Enterobacter aerogenes strains resistant to imipenem and colistin in a patient
Q35536173Survey of resistance of Pseudomonas aeruginosa from UK patients with cystic fibrosis to six commonly prescribed antimicrobial agents
Q36630395Symbiotic conversations are revealed under genetic interrogation
Q41478684Temperature-regulated efflux pump/potassium antiporter system mediates resistance to cationic antimicrobial peptides in Yersinia
Q35191536The ColRS signal transduction system responds to the excess of external zinc, iron, manganese, and cadmium
Q31069986The MisR/MisS two-component regulatory system influences inner core structure and immunotype of lipooligosaccharide in Neisseria meningitidis.
Q41011635The O-antigen negative ∆wbaV mutant of Salmonella enterica serovar Enteritidis shows adaptive resistance to antimicrobial peptides and elicits colitis in streptomycin pretreated mouse model
Q36239489The PhoP-PhoQ two-component regulatory system of Photorhabdus luminescens is essential for virulence in insects
Q34434883The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella enterica
Q50082682The PmrA/PmrB and RcsC/YojN/RcsB systems control expression of the Salmonella O-antigen chain length determinant.
Q36385836The PmrAB system-inducing conditions control both lipid A remodeling and O-antigen length distribution, influencing the Salmonella Typhimurium-host interactions
Q44581662The PmrA‐PmrB two‐component system responding to acidic pH and iron controls virulence in the plant pathogen Erwinia carotovora ssp. carotovora
Q36163103The Pseudomonas aeruginosa PhoP-PhoQ two-component regulatory system is induced upon interaction with epithelial cells and controls cytotoxicity and inflammation
Q40271896The Salmonella membrane protein IgaA modulates the activity of the RcsC-YojN-RcsB and PhoP-PhoQ regulons
Q34000770The alternative sigma factor, sigmaE, is critically important for the virulence of Salmonella typhimurium
Q35287946The broadly conserved regulator PhoP links pathogen virulence and membrane potential in Escherichia coli
Q37853852The diversity of insect-bacteria interactions and its applications for disease control
Q37410213The dlt operon of Bacillus cereus is required for resistance to cationic antimicrobial peptides and for virulence in insects.
Q34647328The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiota
Q39520595The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications
Q34697528The lipid A 1-phosphatase of Helicobacter pylori is required for resistance to the antimicrobial peptide polymyxin
Q42949034The lipopolysaccharide of Brucella abortus BvrS/BvrR mutants contains lipid A modifications and has higher affinity for bactericidal cationic peptides
Q27313421The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea
Q40730520The pbgPE operon in Photorhabdus luminescens is required for pathogenicity and symbiosis
Q24548929The pleiotropic two-component regulatory system PhoP-PhoQ
Q37254531The structurally similar, penta-acylated lipopolysaccharides of Porphyromonas gingivalis and Bacteroides elicit strikingly different innate immune responses.
Q27698393The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity
Q34757004Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes
Q28534775Toward repurposing ciclopirox as an antibiotic against drug-resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae
Q41901966Transcriptional analysis of a Photorhabdus sp. variant reveals transcriptional control of phenotypic variation and multifactorial pathogenicity in insects
Q47316351Transcriptional control of the antimicrobial peptide resistance ugtL gene by the Salmonella PhoP and SlyA regulatory proteins
Q38330625Transcriptional regulation of the 4-amino-4-deoxy-L-arabinose biosynthetic genes in Yersinia pestis
Q28344828Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria
Q36396834Transposon mutagenesis of Salmonella enterica serovar Enteritidis identifies genes that contribute to invasiveness in human and chicken cells and survival in egg albumen.
Q92633929Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis
Q33186065Unexpected catalytic site variation in phosphoprotein phosphatase homologues of cofactor-dependent phosphoglycerate mutase
Q42905654Unsaturated long chain free fatty acids are input signals of the Salmonella enterica PhoP/PhoQ regulatory system
Q46522626Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica
Q28483901Very long O-antigen chains enhance fitness during Salmonella-induced colitis by increasing bile resistance
Q37900143Virulence properties of the legionella pneumophila cell envelope.
Q34312354mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides
Q35949418pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine.

Search more.