Identification of cptA, a PmrA-regulated locus required for phosphoethanolamine modification of the Salmonella enterica serovar typhimurium lipopolysaccharide core

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Identification of cptA, a PmrA-regulated locus required for phosphoethanolamine modification of the Salmonella enterica serovar typhimurium lipopolysaccharide core is …
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scholarly articleQ13442814

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P356DOI10.1128/JB.187.10.3391-3399.2005
P932PMC publication ID1112023
P698PubMed publication ID15866924

P2093author name stringR Carlson
J S Gunn
B Choudhury
M Merighi
R Tamayo
A Septer
P2860cites workOne-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
lpt6, a gene required for addition of phosphoethanolamine to inner-core lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzaeQ28484981
Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinantQ29615039
Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporationQ31006759
An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donorQ31006859
Resistance to host antimicrobial peptides is necessary for Salmonella virulenceQ31030619
A low pH-inducible, PhoPQ-dependent acid tolerance response protects Salmonella typhimurium against inorganic acid stressQ33730040
Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimuriumQ34004929
Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivoQ34007636
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensinQ34186394
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.Q34286908
The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella entericaQ34434883
Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunityQ34469853
Closing the loop: the PmrA/PmrB two-component system negatively controls expression of its posttranscriptional activator PmrD.Q34959854
Phosphorylation of the Lipid A Region of Meningococcal Lipopolysaccharide: Identification of a Family of Transferases That Add Phosphoethanolamine to LipopolysaccharideQ35006104
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity.Q35137651
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulentQ35617117
Bacterial infection as assessed by in vivo gene expressionQ35966527
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replicationQ36602184
Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genesQ36812913
Lipid A and resistance of Salmonella typhimurium to antimicrobial granule proteins of human neutrophil granulocytesQ37096862
Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomesQ37265751
Identification and functional analysis of Salmonella enterica serovar Typhimurium PmrA-regulated genesQ38331209
Neisserial lipooligosaccharide is a target for complement component C4b. Inner core phosphoethanolamine residues define C4b linkage specificity.Q38349640
Genetics of the (gram-negative) bacterial surfaceQ38999038
Two-component regulatory systems can interact to process multiple environmental signalsQ39843585
PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistanceQ39843622
Regulation of polymyxin resistance and adaptation to low-Mg2+ environmentsQ39847917
Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimuriumQ39973551
Connecting two-component regulatory systems by a protein that protects a response regulator from dephosphorylation by its cognate sensorQ40016679
A small protein that mediates the activation of a two-component system by another two-component systemQ40370371
Isolation and characterization of lipopolysaccharides, lipooligosaccharides, and lipid A.Q40687425
Identification of a gene (lpt-3) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosisQ43944920
PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistanceQ48038471
Construction of targeted single copy lac fusions using lambda Red and FLP-mediated site-specific recombination in bacteriaQ48298401
The structure of the linkage between the O-specific polysaccharide and the core region of the lipopolysaccharide from Salmonella enterica serovar Typhimurium revisitedQ50121868
Mg2+ as an extracellular signal: environmental regulation of Salmonella virulenceQ50140541
Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR studyQ50151855
A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cellsQ50195971
Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimuriumQ50216500
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectSalmonella entericaQ2264864
lipopolysaccharideQ421804
P304page(s)3391-3399
P577publication date2005-05-01
P1433published inJournal of BacteriologyQ478419
P1476titleIdentification of cptA, a PmrA-regulated locus required for phosphoethanolamine modification of the Salmonella enterica serovar typhimurium lipopolysaccharide core
P478volume187

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cites work (P2860)
Q36479175A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis.
Q33535665A link between the assembly of flagella and lipooligosaccharide of the Gram-negative bacterium Campylobacter jejuni
Q31103972A novel plasmid-encoded serotype conversion mechanism through addition of phosphoethanolamine to the O-antigen of Shigella flexneri
Q51549048A phosphoethanolamine transferase specific for the 4'-phosphate residue of Cronobacter sakazakii lipid A.
Q42035699Absence of PmrAB-mediated phosphoethanolamine modifications of Citrobacter rodentium lipopolysaccharide affects outer membrane integrity
Q33996834Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides
Q41206980Altered host immune responses to membrane vesicles from Salmonella and Gram-negative pathogens.
Q38348964Antibacterial mechanisms of polymyxin and bacterial resistance.
Q36757725Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
Q36720179Bacterial Evasion of Host Antimicrobial Peptide Defenses
Q38026594Bacterial resistance to cationic antimicrobial peptides
Q47154422Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms
Q38835006Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Q36159546Cationic antimicrobial peptides serve as activation signals for the Salmonella Typhimurium PhoPQ and PmrAB regulons in vitro and in vivo
Q35728329Characterization of unique modification of flagellar rod protein FlgG by Campylobacter jejuni lipid A phosphoethanolamine transferase, linking bacterial locomotion and antimicrobial peptide resistance
Q33842938Conflicting roles for a cell surface modification in Salmonella
Q34088577Contribution of bacterial outer membrane vesicles to innate bacterial defense.
Q34044891Contribution of the lipopolysaccharide to resistance of Shigella flexneri 2a to extreme acidity
Q36558779EptC of Campylobacter jejuni mediates phenotypes involved in host interactions and virulence
Q48346122Expanding the paradigm for the outer membrane: Acinetobacter baumannii in the absence of endotoxin
Q54949785Experimental evolution of resistance to an antimicrobial peptide.
Q41352857Extracellular zinc induces phosphoethanolamine addition to Pseudomonas aeruginosa lipid A via the ColRS two-component system
Q37910758Extreme antimicrobial Peptide and polymyxin B resistance in the genus burkholderia
Q38037528Extreme antimicrobial peptide and polymyxin B resistance in the genus Burkholderia.
Q33580760Functional identification of Proteus mirabilis eptC gene encoding a core lipopolysaccharide phosphoethanolamine transferase.
Q28492779Genetic and functional analyses of PptA, a phospho-form transferase targeting type IV pili in Neisseria gonorrhoeae
Q35103882Identification of the lipopolysaccharide modifications controlled by the Salmonella PmrA/PmrB system mediating resistance to Fe(III) and Al(III).
Q24650951Lipid A modification systems in gram-negative bacteria
Q38287949Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria
Q47397990MgrB Alterations Mediate Colistin Resistance in Klebsiella pneumoniae Isolates from Iran
Q36804404Modulation of hexa-acyl pyrophosphate lipid A population under Escherichia coli phosphate (Pho) regulon activation
Q36708500Molecular and structural basis of inner core lipopolysaccharide alterations in Escherichia coli: incorporation of glucuronic acid and phosphoethanolamine in the heptose region
Q46304715New Features in the Lipid A Structure of Brucella suis and Brucella abortus Lipopolysaccharide
Q40046802Novel Coordination of Lipopolysaccharide Modifications in Vibrio cholerae promotes CAMP resistance.
Q35967793On the in vivo significance of bacterial resistance to antimicrobial peptides
Q42909802PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium.
Q35527834Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro
Q37099451Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum
Q64896563PmrC (EptA) and CptA Negatively Affect Outer Membrane Vesicle Production in Citrobacter rodentium.
Q38922536Polymyxin: Alternative Mechanisms of Action and Resistance.
Q92302848Polymyxins: Mode of Action
Q42077622Reciprocal control between a bacterium's regulatory system and the modification status of its lipopolysaccharide
Q26776000Regulated Control of the Assembly and Diversity of LPS by Noncoding sRNAs
Q34110005Resolvase-in vivo expression technology analysis of the Salmonella enterica serovar Typhimurium PhoP and PmrA regulons in BALB/c mice
Q34999695Review: Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa.
Q33704910Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity.
Q61806012Signal Transduction Proteins in : Role in Antibiotic Resistance, Virulence, and Potential as Drug Targets
Q90291236Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium
Q35191536The ColRS signal transduction system responds to the excess of external zinc, iron, manganese, and cadmium
Q50082682The PmrA/PmrB and RcsC/YojN/RcsB systems control expression of the Salmonella O-antigen chain length determinant.
Q36385836The PmrAB system-inducing conditions control both lipid A remodeling and O-antigen length distribution, influencing the Salmonella Typhimurium-host interactions
Q30370110The Vibrio cholerae VprA-VprB two-component system controls virulence through endotoxin modification.
Q34697528The lipid A 1-phosphatase of Helicobacter pylori is required for resistance to the antimicrobial peptide polymyxin
Q35949418pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine.

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